bleeding, TTP
ADP/P2Y12 inhibitors AE's? (2)
dyspnea, high risk of intracranial bleeding, bradycardia
Ticagrelor AE's?
GI/intracranial bleeding, thrombocytopenia
Glycoprotein IIb/IIIa inhibitors AE's ?
headaches, palpitations, GI upset
PDE3 inhibitors AE's? (3)
HIT, bleeding; osteoporosis, fractures, mineralocorticoid deficiency (long-term)
Heparin AE's? (5)
HIT; allergic response
UFH has the worst _______ & ________ out of the heparin products.
TTP, HIT, bleeding, severe HTN, advanced hepatic/renal disease
Contraindications for Heparin? (5)
renal/hepatic impairment
Contraindications for Direct factor Xa inhibitors?
orthostatic hypotension, reflex tachycardia, headache, retention of salt/water
AE's of NTG? (4)
dizziness, headache, nausea, constipation
AE's of Ranolazine (4)
stroke, transient ischemic attack
CIs of Prasugrel? (2)
bleeding (mostly upper GI), GI upset, headache, tinnitus, dizzy, N/V
AE's of Aspirin? (6)
PPI, propranolol, diazepam, TCA
What drug interactions can occur with Clopidogrel? (4)
rifampin, phenytoin, carbamazepine
Which inducers of CYP3A4 do we avoid with Ticagrelor? (3)
macrolides, ketoconazole, -navirs
Which inhibitors of CYP3A4 do we avoid with Ticagrelor?