J: Quiz Stamp: None CW: Meiosis Quiz / Notebook Setup HW: Notebook Setup & Interactive Reader Pgs. Due Monday, February 2nd • Honors: 143-145 • Regular: 109-121 Left Side, pg # Right Side, pg # (31) Determining Traits Notes (32) Simple Genetics Practice Problems (33) Dihybrid Crosses Notes (34) Traits and Probability Reinforcement (35) Beyond Mendel Guided Notes (36) Incomplete/Co Dominance Examples (37) X Linked Genes Notes (38) X Linked Examples (39) Pedigree Guided Notes (40) Pedigree Practice (41) Review Questions (42) Review Answers J: How are traits passed from one generation to the next? TI: None CW: Gregor Mendel & Trait Notes / Notebook Setup • Update your table of contents. Title & number each page Left Side, pg # Right Side, pg # (31) Determining Traits Notes (32) Simple Genetics Practice Problems HW: Reader Pgs. 143-145 Due Monday, 2/2, Punnett Square wkst #1 DUE F 1/30 Copy Yellow Text into your notebooks Born in 1852 in Czech Republic Spent 14 years working in monastery and teaching Discovered genetics working with peas in monastery garden Gregor Mendel’s experiments with pea plants laid the foundation for genetics Blending Hypothesis Traits from mother and traits from father blend together These traits cannot be separated! Like coffee mixed with cream Particulate Hypothesis Traits from mother and father are kept separate from each other Some traits are hidden by more powerful traits Mendel mated true-breeding father (Yellow peas) with true-breeding mother (Green peas). True-Breeding: produce offspring identical to Punett Square: Used to test themselves (parent) for possible genecopies of traits they can Each parent has two alleles: give to child combinations (offspring) Parents Genes: DNA determines the possible alleles (traits) a parent can Ygive to the child Y- allele for yellow pea Y P1 Generation Father y Mother y y- allele for green pea Yy Yy Yellow Yellow Yy Yellow Yy Yellow Father- YY Mother- yy Why did all the peas come out yellow? Where did mothers green pea trait go? • The green pea color (mother’s trait) is recessive to the yellow pea color (father’s trait) so remains hidden behind yellow pea color. All peas appear yellow. • Dominant trait: visible trait • Recessive trait: hidden trait How do we represent a dominant trait? • Dominant trait represented with CAPITAL letter How do we represent a recessive trait? • Recessive trait represented with lower case letter Homozygous alleles- Aka: True-breeding • Homozygous Dominant-YY • Homozygous Recessive- yy Cross Heterozygous pea (Yy)alleles Heterozygous alleles: Yellow 2 different with a Heterozygous Yellow Pea (Yy) • Yy F1 Generation Y- yellow pea y- green pea Phenotype- Physical trait (yellow peas, green peas) Genotype- Genes/Alleles (YY, Yy, yy) Pod Color: Yellow vs. Green Pod Shape: Smooth vs. Constricted Plant Height: Tall vs. Short Flower Color: Purple vs. White J: 10 facts on Bozeman Genetics TI: Punett Square Worksheet #1, Journals Week 19 & 20 (50 pts) CW: Dihybrid Notes, Traits & Probability Reinforcement, Punett Square Work Day- Simple Genetics Problems Worksheet Left Side, pg # Right Side, pg # (31) Determining Traits Notes (32) Simple Genetics Practice Problems (33) Dihybrid Crosses Notes (34) Traits and Probability Reinforcement HW: • Reader Pages 143-145 DUE M 2/2 • Simple Genetics Problem Worksheet (check on M 2/2) • Dihybrid Practice DUE MON 2/2 You are still required to turn in ALL work due today. Please behave and be respectful! Mrs. Narubin will be providing you with the information for todays lecture. You are required to be on your BEST behavior! Any disturbances or rudeness will result in an immediate referral and removal from the class. J:Describe the difference between heterozygous and homozygous. Give examples of each. TI: Reader pages 143-145 & Dihybrid Wkst CW: Fill in Beyond Mendel Guided Notes (Update your Table of Contents, Title & Number each page! Pick up the two handouts and add them to appropriate page) Left Side, pg # Right Side, pg # (35) Beyond Mendel Guided Notes (36) Incomplete/Co Dominance Examples HW: Finish Incomplete/ Codominance practice Questions DUE T 2/3 Co- dominance, Incomplete dominance and multiple alleles In some cases, an intermediate phenotype is shown Neither allele is dominant In snapdragons, flower color can be red, pink, or white. The heterozygous condition results in pink flowers (or an intermediate trait) A white snapdragon crossed with a red snapdragon produces all pink offspring Two pinks crossed together • produce 1/4 white, 2/4 pink, and 1/4 red Try These Crosses in your Notes! •Sickle cell disease is incompletely dominant in humans. AA x aa = Aa (sickle cell trait), where some blood cells will have abnormal shapes Both alleles can be expressed For example, red cows crossed with white will generate roan cows. Roan refers to cows that have red coats with white blotches. This phenotype might seem to support the blending theory. (The blending theory predicts pink F1 progeny.) The phenotypic outcomes for cow color and incomplete dominance in general can be explained biochemically. One allele of the gene codes for an enzyme that functions in the production of the red color. The other allele codes for the gene to make white color. If both alleles are present, both are expressed, resulting in a cow that has some red and some white. In shorthorn cattle, when a red bull (RR) is crossed with a white cow (WW), all the offspring are roan—a spotted, red and white or milky red color. What offspring are expected from mating a roan bull and a roan cow? What phenotypes would you expect from a cross between a red bull and a white cow? In humans, there are four blood types (phenotypes): A, B, AB, and O Blood type is controlled by three alleles. A, B, O O is recessive, two O alleles must be present for the person to have type O blood A and B are co dominant. If a person receives an A allele and a B allele, their blood type is type AB Crosses involving blood type often use an I to denote the alleles - see chart. When doing blood type crosses, you will need to know whether a type A or B person is heterozygous or homozygous. Type O's are automatically OO and type AB is automatically AB. Crosses are performed the same as any other. Blood type determines what antibodies are located within the blood. • Type A =B antibodies. • If type B blood is put into their bodies, their immune system reacts as if it were a foreign invader, the antibodies clump the blood - can cause death. Type AB blood has no antibodies, any blood can be donated to them="universal acceptors" Type O blood has no surface markers on it, antibodies in the blood do not react to type O blood, ="universal donors" J:Complete the cross: • BB= Black / BW= Black with White Spots / WW = White • BB x BW • List the genotypes and phenotypes once done with the cross. TI: none CW: Oompa Loompa Worksheet Practice Day Left Side, pg # Right Side, pg # (35) Beyond Mendel Guided Notes (36) Incomplete/Co Dominance Examples HW: Oompa Loompa DUE W 2/4 J: Explain the difference between co dominance and incomplete dominance. Give an example of each TI: Oompa Loompa wkst CW: Sex-linked (37) X Linked Genes Notes HW: Sex Genetics Notes & Practice (38) X Linked Examples Linked Wkst DUE Th 2/5 Chromosomal Theory of Inheritance: simply states that chromosomes are carriers of genetic information (Walter Sutton) Humans have 22 pairs of autosomes, 1 pair of sex chromosomes Fruit flies have 3 pairs of autosomes, 1 pair of sex chromosomes What is the sex of this person? Female eggs = XX Male sperm = XY Possible offspring are shown in square: 50% male 50% female What happens when an allele is located on the X chromosome? Males only get ONE ! These are a few of the known alleles located on the X chromosome Disorders that are recessive are masked in females by the other X chromosome. Sex Linked Genes •Genes located on the X chromosome are inherited with that X. •When doing crosses you must include the sex chromosomes in your cross. •Use superscript letters for the allele. Example: In fruit flies, eye color is a sex linked trait. Red is dominant to white. Females XRXR XRXr XrXr Males XR Y Xr Y Thomas Morgan used crosses with fruit flies. Why do you think he used them? What is an autosome? Show the cross between a white eyed male and a red eyed female: XrY x XRXR Show the cross between a red eyed male and a white eyed female: 1. Colorblindness 2. Muscular Dystrophy 3. Hemophilia 4. Fragile X Syndrome Muscular Dystrophy • characterized by the wasting away of muscles • life expectancy: ~20 yrs • females can be carriers for the disease, where they pass the disease to their sons only Show the cross of a female who is a carrier and a normal male: Fragile X Syndrome • caused by triplet repeats in a gene on the X chromosome • causes mental retardation • named because the X chromosome had an odd appearance - the tip of the chromosome seemed to be attached only by a small thread • the number of repeats of the gene determines the severity of the disease • also known as "bleeder's disease", blood does not clot properly • disease was present in the royal family, starting with Queen Victoria Show the cross between a female with hemophilia and a normal man: J: Complete the sex linked cross: • B= Not bald / b = bald • A bald man with a carrier female • List the genotypes and phenotypes for both sexes. TI: Sex Linked Wkst CW: New Seats, Pass back all work, Pedigree Notes And Practice (39) Pedigree Guided Notes (40) Pedigree Practice (41) Review Topic 1 & 2 (42) Review Topic 3&4 HW: Review for Unit 4: Genetics Test T 2/10 *** If you are new to class you will need to have 5 3 prong folders by next Tues 2/10*** (See me if you have any concerns) Unit 4 Genetics Folder DUE W 2/11- Make sure all pages are complete, table of contents updated, pages are titled and numbered, essential questions are answered, and concept map is complete Squares represent males Circles are used for females A horizontal line from male to female represents mates that have produced offspring The offspring are listed below their parents from oldest to youngest A fully shaded individual posses the trait being studied • If the condition being studied is a monogenic recessive condition (rr), then those shaded gray have the genotype rr • If the condition being studied is dominant condition (Rr or RR), then those that are unshaded have the genotype rr A line through a symbol indicated that the person is deceased J: Is this a sex linked trait? What must the identified mother’s genotype be? TI: none CW: Unit 4 Review HW: Finish Review / Test Monday J- NONE TI- none CW- Science Course Assembly • Expectations (39) Pedigree Guided Notes (40) Pedigree Practice (41) Review Topic 1 & 2 (42) Review Topic 3&4 HW- Unit 4: Genetics Test T 2/10 (200 pts) Complete reviews on pgs 39 & 40 DUE T 2/10 (40 pts) *** If you are new to class you will need to have 5 3 prong folders by next Tues 2/10*** (See me if you have any concerns) Unit 4 Genetics Folder DUE W 2/11• Make sure all pages are complete, table of contents updated, pages are titled and numbered, essential questions are answered, and concept map is complete J-What were the two topics covered on the review that you understood the best? What two topics do you understand the least? TI- none CW- Partner Test Review (14 pts) Left Side, pg # Right Side, pg # (43) Partner Review Questions (44) Partner Review Answers HW- Unit 4: Genetics Test T 2/10 (200 pts) Complete reviews on pgs 39 & 40 DUE T 2/10 (40 pts) *** If you are new to class you will need to have 5 3 prong folders by next Tues 2/10*** (See me if you have any concerns) Unit 4 Genetics Folder DUE W 2/11• Make sure all pages are complete, table of contents updated, pages are titled and numbered, essential questions are answered, and concept map is complete J- Test reflection. (3 sentence minimum) • What did you struggle on? What did you do well on? Any strategies you plan to use next test? TI- Checking Review pages 41 & 42 CW- Unit 4 Genetics Test (200pts) HW- Bring in Unit 5 folder • *** If you are new to class you will need to have 5 3 prong folders by next Tues 2/10*** (See me if you have any concerns) • Unit 4 Genetics Folder DUE W 2/11 Make sure all pages are complete, table of contents updated, pages are titled and numbered, essential questions are answered, and concept map is complete