Medicines and Drugs Unit (Option D – Chapter 15) The options are different than the core units. They represent application of the core units into specific topic areas. Reading and processing what you read is very important. Memorizing information will be a key to your success on Paper 3 questions. Try something new… read the section BEFORE you come to class. This may allow you to reach better understanding than waiting until after the lecture . A number of students find this a helpful technique for college classes. Topic D.1 Pharmaceutical Products IB Syllabus D.1.1: List the effects of drugs and medicines on the functioning of the body. D.1.2: Outline the stages involved in research, development and testing of new pharmaceutical products. D.1.3: Describe the different methods of administering drugs. D.1.4: Discuss the terms therapeutic window, tolerance, and side effects. Expert = Ms. Smith D.2 Antacids D.2.1: State and explain how excess acidity in the stomach can be reduced by the use of different bases. Expert = 1. Victoria D.3 Analgesics D.3.1: Describe and explain the different ways in which analgesics prevent pain. D.3.2: Describe the use of derivatives of salicylic acid as mild analgesics and compare the advantages and disadvantages of using aspirin and paracetamol (acetaminophen). D.3.3: Compare the structures of morphine, codeine, and diamorphine (heroin, the semi-synthetic opiate). D.3.4: Discuss the adv and disadvantages of using morphine and its derivatives as strong analgesics. Experts= 2. Jonathan 3. Alex D.4 Depressants D.4.1: Describe the effects of depressants. D.4.2: Discuss the social and physiological effects of the use and abuse of ethanol. D.4.3: Describe and explain the techniques used for the detection of ethanol in the breath and in the blood or urine. D.4.4: Describe the synergistic effects of ethanol with other drugs. D.4.5: List other commonly used depressants and describe their structures. Experts = 4. Mickella 5. Ryan D.5 Stimulants D.5.1: List the physiological effects of stimulants. D.5.2: Compare amphetamines and adrenaline (epinephrine). D.5.3: Discuss the short-and long-term effects of nicotine consumption. D.5.4: Describe the effects of caffeine and compare its structure with that of nicotine. Experts = 6. Adie 7. Sarah Reading and Related Questions Read pp. 405-410 Take NOTES and/or Do Qs 1 & 2 on p 434 and/or Practice with online flash cards * Make online flashcards Read pp. 410-411 Take NOTES or Do Q 3 on p 434 * Make online flashcards Read pp. 412-414 Take NOTES or Do Qs 4,5,& 6 on p 434 * Make online flashcards Read pp. 415-419 Take NOTES or Do Qs 7,8,9,& 10 on p 435 * Make online flashcards Read pp. 419-421 Take NOTES or Do Qs 11 & 12 on p 435 * Make online flashcards D.6 Anti-Bacterials D.6.1: Outline the historical development of penicillins. D.6.2: Explain how penicillins work and discuss the effects of modifying the side chain. D.6.3: Discuss and explain the importance of patient compliance and the effect of penicillin overprescription. Experts = 8. Abbie 9. Leann D.7 Anti-Virals D.7.1: State how viruses differ from bacteria. D.7.2: Describe the different ways in which antiviral drugs work. D.7.3: Discuss the difficulties associated with solving the AIDS problem. Experts = 10. Molly 11. D.8 Drug Action D.8.1: Describe the importance of geometrical isomerism in drug action D.8.2: Discuss the importance of chirality in drug action. D.8.3: Explain the importance of beta-lactam ring action of penicillin. D.8.4: Explain the increased potency of diamorphine (heroin) compared to morphine. Experts = 12. Tyler 13. D.9 Drug Design D.9.1: Discuss the use of a compound library in drug design D.9.2: Explain the use of combinatorial and parallel chemistry to synthesize new drugs. D.9.3: Describe how computers are used in drug design D.9.4: Discuss how the polarity of a molecule can be modified to increase its aqueous solubility and how this facilitates its distribution around the body. D.9.5 Describe the use of chiral auxillaries to form the desired enantiomer. Experts = 14. Luca 15. Diana D.10 Mind-Altering Drugs D.10.1: Describe the effects of lysergic acid diethylamide (LSD), mescaline, psilocybin and tetrahydrocannabinol (THC). D.10.2: Discuss the structural similarities and differences between LSD, mescaline and psilocybin. D.10.3: Discuss the arguments for and against the legalization of cannabis. Experts = 16. Lee 17. Hunter Read pp. 422-424 Take NOTES or Do Q 13 on p 435 * Make online flashcards Read pp. 424-425 Take NOTES or Do Q 14 on p 435 * Make online flashcards Read pp. 425-427 Take NOTES or Do Qs 15,16,&17 on p 436 * Make online flashcards Read pp. 427-431 Take NOTES or Do Qs 18,19,&20 on p 436 * Make online flashcards Read pp. 431-434 Take NOTES or Do Qs 21 & 22 on p 436 * Make online flashcards Flashcards …. Use QUIZLET… set up free account at http://quizlet.com/ I’ve put flashcards for D1 in this group… PHS IB HL Chemistry… …. you will need a password to access (smith). You must create your flashcards in this same group… add a set… name needs to include section! Let me know if you have trouble… smithsj@d11.org or 719-963-2973.