AMINO ACIDS Amino acids are the monomers from which proteins are made. The general structure of an amino acid as: where NH2 represents an amine group, COOH represents a carboxyl group and R represents a carbon-containing side chain. The twenty amino acids that are common in all organisms differ only in their side group. Amino acids https://www.youtube.com/watch?v=MYmCGMQkCb0 During the clip, try and name some of the Amino acids they mention – competition for the most got! Amino acids are the monomers that make up proteins. All Proteins (also called polypeptides) are made up from the 20 different amino acids. Outcomes: - Name the monomers that polymerise to form proteins - Describe the chemical groups of an amino acid - Name and draw some different amino acids with the R groups. - Explain how peptide bonds are formed and broken between amino acids to form/break dipeptides. - Use structural formula to show condensation and hydrolysis reactions of amino acids. Amino acid structure All amino acids have this structure. The R group (side chain) differs for each amino acid. Task: Draw this and find the side groups of 3 amino acids and draw and label these too. Outcomes: - Name the monomers that polymerise to form proteins - Describe the chemical groups of an amino acid - Name and draw some different amino acids with the R groups. - Explain how peptide bonds are formed and broken between amino acids to form/break dipeptides. - Use structural formula to show condensation and hydrolysis reactions of amino acids. There are 20 amino acids, how many proteins are there? Proteins (polypeptides) are made of large amounts of amino acids joined up together in a specific order. Because of this you can make millions of different proteins just using the 20 different amino acids. Task: How many polypeptides can you make from just 3 amino acids. Outcomes: - Name the monomers that polymerise to form proteins - Describe the chemical groups of an amino acid - Name and draw some different amino acids with the R groups. - Explain how peptide bonds are formed and broken between amino acids to form/break dipeptides. - Use structural formula to show condensation and hydrolysis reactions of amino acids. Alanine Glycine Alanine Glycine Alanine Glycine Alanine Glycine Leucine Leucine Leucine Leucine Forming – joining FormingDipeptides polypeptides (making proteins): amino acids Breaking down polypeptides (making amino acids): Outcomes: - Name the monomers that polymerise to form proteins - Describe the chemical groups of an amino acid - Name and draw some different amino acids with the R groups. - Explain how peptide bonds are formed and broken between amino acids to form/break dipeptides. - Use structural formula to show condensation and hydrolysis reactions of amino acids. The Peptide bond Q: What was the bond between two monosaccharides called? Q: What do you think the bond between two amino acids will be called? Outcomes: - Name the monomers that polymerise to form proteins - Describe the chemical groups of an amino acid - Name and draw some different amino acids with the R groups. - Explain how peptide bonds are formed and broken between amino acids to form/break dipeptides. - Use structural formula to show condensation and hydrolysis reactions of amino acids. HW: Testing for Amino Acids Research how to identify amino acids/separate a solution of amino acids using Thin Layer Chromatography paper. In your Lab books: Title: Testing for Amino acids in an unknown solution. Write an aim, equipment list, method and risk assessment. Next lesson we are going to do this! Outcomes: - Name the monomers that polymerise to form proteins - Describe the chemical groups of an amino acid - Name and draw some different amino acids with the R groups. - Explain how peptide bonds are formed and broken between amino acids to form/break dipeptides. - Use structural formula to show condensation and hydrolysis reactions of amino acids.