Objectives 1. To identify the ways of preventing diseases. 2. To investigate symptoms, prevention and treatment of common animal diseases. 3. To learn to diagnose common animal diseases. 2 Table of Contents Terminology Disease Treatment & Prevention Methods Nutritional Diseases Bacterial Diseases Viral Diseases Fungal Diseases Parasitic Diseases 3 4 Diseases • Prevent or impair an animal’s daily functioning and can be harmful to development • Can be caused by the following: – nutrient deficiencies – pathogens 5 Nutrient Deficiencies • Result from under consumption of key nutrients • Can affect the internal processes of animals • Lower an animal’s immune system and increase chances of illness 6 Process of Immunity in Animals • Passive immunity – antibodies come from outside the body – not permanent • Active immunity – body produces own antibodies – permanent • Protects animals from – bacteria, viruses and parasites 7 Nutritional Requirements • • • Depend on an animal’s age and function Allow animals to receive a well-balanced diet Include: – – – – – vitamins fats carbohydrates protein minerals 8 Pathogens • Are any organism causing a disease • Can be microscopic or macroscopic Microscopic: an organism too small to be seen by the unaided eye, but large enough to be studied under a microscope. Example: bacteria, viruses Macroscopic: an organism large enough to be perceived or examined by the unaided eye such as a worm or tick 9 Pathogens • Are classified as follows: – viruses – bacteria – parasites – fungi – protozoa Source: www.ars.usda.gov 10 Pathogens 11 Viruses • Cannot reproduce without a host • Consist of DNA and RNA • Can take over the functions of the host cell 12 Bacteria • • • • Are single celled organisms May produce toxins harmful to the body Multiply rapidly without a host Can be identified by shape 13 Bacteria Shapes • Include: – cocci: spherical-shaped – bacilli: rod-shaped – spirilli: spiral-shaped 14 Parasites • Can be external or internal • Effect host animals through contact or ingestion • Have various life cycles • Are living organisms 15 Internal Parasite Life Cycle 16 External Parasite Life Cycle 17 Fungi • Studies are known as mycology • Live in air, soil, plants and water • Produce transmittable spores which can cause fungal diseases Mycology: the study of the characteristics of fungi 18 Protozoa • Greek for first animal • Is a single-celled organism • Breath, move and reproduce similar to multi-cellular animals • Can be classified into many different types 19 20 Parasitic Treatments • • • • Usually involve a type of Anthelmintics Vary depending on the parasite and host Can cause parasite resistance May require a veterinarian's prescription and extended withdrawal time Anthelmintics: an agent which destroys or causes the expulsion of parasitic intestinal worms 21 Vital Signs • Help in early detection of health problems • Vary with activity and environmental conditions • Include: – temperature – pulse rate – respiration rate 22 Vital Signs Species Temperature, °F Pulse Rate, heart beats/min Respiration Rate, breaths/min Cattle 100.4-102.8 60-70 10-30 Sheep 100.9-103.8 70-80 12-20 Goats 101.7-105.3 70-80 12-20 Swine 102.0-103.6 60-80 8-13 Horses 99-100.8 32-44 8-16 23 Prevention • Starts with proper management • Reduces chance of disease • Results in a healthy, productive herd 24 Proper Management • Allows producers to prevent causes, prevent symptoms and treat diseases • Involves the following techniques: – providing shelter – cleaning and sanitizing facilities and equipment – rationing adequate diets – monitoring herd health daily – isolating new animals before introduction to the herd 25 26 Milk Fever • Is a metabolic disorder • Is also known as hypocalcemia • Affects cattle, sheep and goats • Occurs when the animal has low blood calcium levels during lactation 27 Milk Fever • Symptoms include: – muscle tremors – wobbly – downer cow • inability to stand – low body temperature – unconscious/coma 28 Milk Fever • Treatments include: – injecting a solution of calcium borogluconate subcutaneously or intravenously – providing a combined mineral solution Subcutaneously: located or placed just beneath the skin Intravenously: entering by way of vein 29 Milk Fever • Prevention options include: – providing vitamin D, five to seven days before parturition – keeping animals on a low calcium diet while not lactating – providing high doses of calcium one day before and one day after calving • alfalfa hay is high in calcium 30 White Muscle Disease • Is generalized as nutritional muscular dystrophy • Affects young, rapidly growing lambs/kids (from dams with selenium deficient diets) • Affects calves and foals • Is the result of a selenium and/or vitamin E deficiency 31 White Muscle Disease • Affects two different muscle groups, cardiac and skeletal • Cardiac symptoms include: – sudden death – respiratory distress • Skeletal symptoms include: – muscular weakness – inability to stand – muscle tremors Source: www.ars.usda.gov 32 White Muscle Disease • Treatments include: – injections of selenium – oral drenches of selenium/vitamin E • Can be prevented by: – supplementing the diet of susceptible animals with selenium and vitamin E Warning: too much selenium can cause toxicity in animals 33 Bloat • Can occur in all ruminants • Refers to rapid fermentation, producing excess gas or foam in the rumen • Is caused by consuming highly concentrated rations and lush legume pastures Fermentation: breakdown of carbohydrates by enzymes 34 Bloat • Symptoms include: – – – – abdominal distention on left side loss of appetite respiratory distress difficulty walking or moving 35 Bloat • Treatments include: – keeping animal on feet and moving – drenching with mineral oil or poloxalene – putting stomach tube down throat to relieve pressure from gas • Can be prevented by: – feeding dry roughage with a mix of grasses – keeping animals from eating an excess of lush green grass, especially alfalfa • Is difficult to prevent 36 Colic • Is the general term referring to abdominal pain • Mainly impacts horses because they are unable to vomit • Is caused by a wide range of conditions affecting the digestive tract, including: – sudden changes in feed – a predominantly concentrate diet – cribbing – lack of water – presence of bloodworms 37 Colic • Symptoms include: – distended abdomen – rolling and kicking – excruciating pain – sweating – constipation • Can result in a twisted intestine Source: Tiffanie Brooks, D.V.M. Texas Tech University 38 Colic • Treatments include: – – • walking the horse taking to veterinarian—animal might need sedatives, laxatives, pain medicine or surgery Can be prevented by: – – – – – feeding small rations feeding good quality roughages providing clean water monitoring eating habits controlling internal parasites 39 Entertoxemia (Overeating Disease) • Commonly affects sheep and goats • Is caused by toxins produced by naturally occuring intestinal bacteria – Clostridium perfringens types C & D • Occurs usually when an animal consumes excessive amounts of high energy feeds or milk • Produces a quickly absorbed toxin • Can cause acute death 40 Entertoxemia (Overeating Disease) • Symptoms include: – sudden death – diarrhea – neurologic signs • • • • circling head pressing incoordination convulsions 41 Entertoxemia (Overeating Disease) • If caught early, can be treated by: – administering antitoxins – administering oral antibiotics – feeding hay Source: www.ars.usda.gov 42 Entertoxemia (Overeating Disease) • Can be prevented by: – slowly introducing concentrates – careful regulation of energy intake – administering a vaccination against Clostridium perfringens types C & D to pregnant and young animals at approximately four weeks of age Vaccination: injection of a killed microbe in order to stimulate the immune system against the microbe, thereby preventing disease 43 Lactic Acidosis • Also known as carbohydrate engorgement • Affects cattle • Is caused by a sudden shift from a forage-based to a high concentrate diet • Results from low rumen pH due to an increase of propionic acid production Propionic Acid: an acid produced by bacteria in the rumen with a very low pH 44 Lactic Acidosis • Symptoms include: – abdominal distension or bloat – dehydration – diarrhea – sore hooves – liver abscesses – decreased milk production 45 Source: www.ars.usda.gov Lactic Acidosis • Includes the following treatments: – gradually adding more roughages to the diet – adding feed additives to help raise the rumen pH – giving oral antacids – giving oral fluids 46 Lactic Acidosis • Can be prevented by: – maintaining a roughage diet of 10 percent or more – utilizing ionophores as feed additives Ionophores: a group of organic compounds, facilitate the transport of ions across the cell membrane 47 48 Johne’s Disease • Is an incurable wasting disease of adult cattle • Is caused by organisms in the intestinal cells and lymph nodes – organisms are passed out in feces and easily survive in manure • Causes progressive thickening of the intestinal walls • Affects young animals and may not show symptoms until adulthood 49 Johne’s Disease • Can be determined with tests performed by a veterinarian • Symptoms may not be present • Symptoms can include: Source: www.ars.usda.gov – chronic diarrhea – weight loss – lowered milk production 50 Johne’s Disease • Has no effective treatment • Can be prevented by checking health history of animals before purchase 51 Blackleg • Is caused by a spore forming bacterium attacking skeletal muscles • Spores can live in soil for years • Can cause death without any symptoms 52 Blackleg • Symptoms include: – lameness – swelling over neck, shoulder and thighs • will make a crackling sound when rubbed – wounds and bruises occurring in young calves from four months to two years old – death occurs in one or two days 53 Blackleg • Treatment: – massive doses of antibiotics may save animals if detected early, not always effective • Can be prevented by: – administering a vaccination at three to four months of age 54 Foot Rot • Is a contagious disease of sheep, goats and cattle • Is caused by an interaction of two anaerobic bacteria – Fusobacterium necrophorum – Bacteroides nodosus Anaerobic: organisms living without oxygen 55 Foot Rot • Bacteria must penetrate the interdigital epidermis • Causes severe lameness • Contributing factors include: – mud – manure – stones 56 Foot Rot • Symptoms include: – moist and reddened hooves – inflamed interdigital space and coronary band – foul odor – lameness 57 Foot Rot • Treatments include: – foot trimming – antibiotics – zinc sulfate or copper sulfate footbaths – zinc sulfate as a dry chemical 58 Foot Rot • Can be prevented by: – avoid using facilities used by infected animals in the last two weeks prior to foot trimming – trimming and treating the feet of all new animals 59 60 Bluetongue • Is a viral disease mainly affecting sheep and goats but can affect cattle • Can be transmitted by: – – – – insects in utero infected needles semen Source: Dr. CV Kimberling, CSU Veterinary Extension 61 Bluetongue – abortion – weak, “dummy lamb” births – fever – excessive salivation – nasal discharge – inflamed mouths – swelling of muzzle and ears – blue tongue Source: Dr. CV Kimberling, CSU Veterinary Extension • Symptoms include: 62 Bluetongue – controlling vectors – using insecticides Source: Dr. CV Kimberling, CSU Veterinary Extension • Does not have a known cure • Can be prevented by the following: 63 Bovine Virus Diarrhea • Is a viral disease affecting cattle of all ages • Spreads by contact • Is a transplacental pathogen Transplacental: relating to or involving passage through or across the placenta 64 Bovine Virus Diarrhea • Transmitted by blood feeding flies and contact with fomites • Can appear in the following forms: – mild – acute – chronic Fomite: any inanimate object or substance capable of carrying infectious organisms Examples: soil, holding pens, chutes, feeding troughs 65 Bovine Virus Diarrhea • Symptoms of an acute infection: – lethargy – poor appetite – diarrhea – fever – nasal discharge – oral erosions – abortions Source: www.aphis.usda.gov 66 Bovine Virus Diarrhea • Has no cure • Treatments are given to control symptoms • Prevention methods include: – vaccinating animals with a modified live virus 67 Foot-and-Mouth Disease Source: Dr. A.P. Knight, CSU Veterinary Extension • Is a severe, highly contagious viral disease affecting cloven hoofed animals • Leaves recovered animals debilitated • Virus survives in lymph nodes and bone marrow at neutral pH 68 Foot-and-Mouth Disease • Can be spread by physical contact with the virus by susceptible animals • Virus includes more than 60 subtypes Source: Dr. A.P. Knight, CSU Veterinary Extension 69 Foot-and-Mouth Disease – blisters – erosions in the mouth, on teats and hooves – excessive salivation – fever – lameness Source: Dr. A.P. Knight, CSU Veterinary Extension • Symptoms include: 70 Foot-and-Mouth Disease • Treatment: – vaccines must be matched to the specific type and subtype of the virus • Prevention: – observe excessive salivation, or lameness – report any signs of disease to your veterinarian – do not bring prohibited animal products or other at-risk materials from other countries into the United States 71 Porcine Circovirus • Is an emerging problem in the United States • Has two strains including: – PCVD1 – PCVD2 • Is a member of the virus family Circoviridae • Type II is the strain which affects pigs 72 Porcine Circovirus • Symptoms include: – – – – – • poor growth increased mortality weight loss enlarged lymph nodes jaundice Can be present with no symptoms 73 Porcine Circovirus • Includes the following treatment: – vaccines administered to piglets three to five weeks of age in two doses • Can be controlled by: – sanitizing facilities – quarantine new and sick animals from the herd – lowering stress of animals – increasing immune system through proper nutrition 74 Avian Influenza • Affects turkeys and chickens • Is transmitted through inhalation of feces from an infected bird • Ranges from a mild to a highly fatal disease depending on the strain 75 Avian Influenza • Symptoms include: – – – • coughing sneezing weight loss Treatment: – antibiotics for infected birds 76 Avian Influenza • Can be prevented by: – – – decreasing contact with feces of wild birds avoiding live markets using good sanitation practices 77 Sore Mouth (Orf) • Is the most common skin disease affecting sheep and goats • Is a viral infection • Can produce painful human infections • Affects young animals more frequently Source: Dr. CV Kimberling, CSU Veterinary Extension 78 Sore Mouth (Orf) • Symptoms include: – loss of appetite – vesicles appear on lips, gums and tongue, causing redness or swelling – vesicles break and form sores 79 Sore Mouth (Orf) • Is a self-limiting infection • Treatments include: – applying antibiotic ointment to the sores – tube feeding young individuals if not nursing • Can be prevented by: – good sanitation – vaccination Source: Dr. CV Kimberling, CSU Veterinary Extension 80 81 Ringworm • • • • • Known as Club Lamb Fungus Affects all animals Is highly contagious Can be transmitted to humans Is a fungus which invades the skin and hair (wool) 82 Ringworm • Symptoms include: – lesions appearing on the head, neck and back – hair loss around infected area Source: Dr. C.V. Kimberling, CSU Veterinary Extension Source: Dr. A.P. Knight, CSU Veterinary Extension 83 Ringworm • Treatment: – applying anti-fungal ointments to lesions • Can be prevented by: – proper sanitation of brushes, clippers and bedding – minimizing contact with infected animals 84 Facial Eczema • Is a type of sunburn • Affects grazing animals • Is caused by a poisonous substance "sporidesmin” produced by fungus on pasture plants • Causes liver damage 85 Facial Eczema • Symptoms include: – sunburn – puffy eyes – puffy face – rapid weight loss – jaundice 86 Facial Eczema • Includes the following treatments: – sheltering animals from direct sunlight – removing animal from infected field – contacting a veterinary practitioner 87 Facial Eczema • Prevention methods include: – keeping track of fungi counts in pastures – minimizing close grazing of pasture – shifting livestock to the pastures with low fungi counts 88 89 Mange • Affects all animals • Is caused by an external parasite • Can be identified in various types, including: – sarcoptic mange – psoroptic mange – chorioptic mange – demodectic mange – psorergatic mange • Is most commonly identified as Chorioptic Mange in the United States 90 Mange • Symptoms include: – lesions – itchiness – crusts and scabs – hair loss – ulcerations on the legs Source: Dr. A.P. Knight, CSU Veterinary Extension – weight loss – decreased milk production – increased susceptibility to other diseases 91 Mange • Treatments include: – spraying the animal with a medicated solution at high pressure – using a lime-sulfur dip weekly in cattle • Can be prevented by: – avoiding close confinement – keeping animals outdoors as much as possible – quarantining new animals 92 Coccidiosis • Is caused by a number of protozoan from the family Coccidia • Is caused by protozoan rupturing the intestinal cell lining • Can be found in all animals, mostly in poultry and cattle Protozoan: predominately single cell organism housing a membrane bound nucleus and belonging to the protista kingdom 93 Coccidiosis • Symptoms include: – diarrhea (bloody at times) – straining – loss of appetite – fever 94 Coccidiosis • Includes the following treatment: – sulfonamides is the drug mostly used • Can be prevented by: – good sanitation – placing sulfa guanidine or nitrofurazone in feed or water – using a feed with correct minerals and antibiotics 95 Ostertagious • Is the principal worm parasite of beef and dairy cattle • Attacks the lining of the abomasum • Causes irritation and interferes with the digestive function 96 Ostertagious • Symptoms include: – decreased weight gain – decreased milk production – Ioss of blood protein – diarrhea 97 Ostertagious • Includes the following treatments: – administered at three-week intervals • Thiabendazole • Ivermectin • Can be prevented by: – administering one or more anthelmintic treatments during a production cycle – providing higher levels of protein in the diet – late turnout onto pasture in the spring 98 Haemonchus Contortus • Is better known as the "barber pole" or wire worm • Is the single most deadly stomach worm • Affects sheep in warm, moist climates • Pierces the lining of the abomasum, causing protein loss 99 Haemonchus Contortus • Symptoms include: – anemia – pale mucous membranes – swelling under the jaw 100 Haemonchus Contortus • Treatment: – deworming using: • Levamisole • Ivermectin • Thiabendazole • Can be prevented by: – deworming at birth – carefully monitoring herds 101 Ascaris • Is a common parasite affecting swine of two to three months of age • Is generally known as roundworms • Resides in the stomach, intestinal tract and even the lungs of swine • Can be transmitted to humans through ingestion 102 Ascaris • Symptoms include: – weight loss – slow weight gain – abdominal pain – coughing or trouble breathing – pneumonia 103 Ascaris • Includes the following treatments: – deworming animals using medicines such as: • Fenbendazole • Doramectin • Levamisole • Can be prevented by: – – – – thorough cleaning and sanitation control of pests and rodents minimizing traffic good nutrition 104 105 Assessment 1. Which of the following CANNOT can cause disease? A. Fungi B. Viruses C. Vitamins D. Parasites 2. Nutrient deficiencies are caused by a lack of all but which of the following? A. Liquids B. Vitamins C. Minerals D. Protein 106 Assessment 3. A cocci bacterium is shaped like which of the following? A. Rod B. Spiral C. Spherical D. Circular 4. Which of the following is the study of fungi? A. Organism B. Mycology C. Polypore D. Mushroom 107 Assessment 5. Which of the following is a metabolic disorder occurring when an animal has a low blood calcium level? A. White muscle disease B. Milk fever C. Colic D. Bloat 6. Which of the following digestive tract disease mainly affects horses? A. Colic B. Bloat C. Johne’s disease D. Acidosis 108 Assessment 7. Which of the following is NOT a vital sign? A. Blood sugar level B. Temperature C. Pulse rate D. Respiration rate 8. Which of the following is a nutritional disease relating to the process of fermentation? A. Entertoxemia B. Colic C. Milk fever D. Bloat 109 Assessment 9. White muscle disease affects cardiac as well as which of the following muscles? A. Vascular B. Skeletal C. Muscular D. Vervous 10. Which disease is caused by a spore forming bacterium? A. Blackleg B. Lactic acidosis C. Foot-and-mouth disease D. Bovine virus diarrhea 110 Assessment 11. Foot rot is caused by which of the following? A. Anaerobic bacteria B. Proper management C. Soil fungus D. Poor digestive health 12. Which of the following is a disease which can only be transmitted through insects? A. Blackleg B. Ringworm C. Bluetongue D. Foot rot 111 Assessment 13. Which viral disease has no known cure? A. Ringworm B. Bovine virus diarrhea C. Avian influenza D. Foot rot 14. Foot-and-mouth disease has more than how many subtypes? A. 20 B. 30 C. 50 D. 60 112 Assessment 15. Avian influenza can be prevented by avoiding which of the following? A. Live markets B. Antibiotics C. Pesticides D. Vitamins 16. Which viral disease can also infect humans? A. Sore mouth B. Bovine virus diarrhea C. Acidosis D. Avian influenza 113 Assessment 17. Which of the following is a common symptom among viral diseases? A. Fever B. Frequent urination C. Hyperactivity D. Vomiting 18. Club lamb fungus is another name for which of the following? A. Facial eczema B. Mange C. Ringworm D. Sore mouth 114 Assessment 19. The main symptom of facial eczema is which of the following? A. Weight gain B. Lesions C. Diarrhea D. Sunburn 20. The most common form of mange in the Untied States is which of the following? A. Psoroptic mange B. Chorioptic mange C. Demodectic mange D. Sarcoptic mange 115 Assessment 21. The principle worm parasite in beef interferes with what functions? A. Respiratory B. Cardiac C. Muscular D. Digestive 22. Which of the following is NOT the most deadly stomach worm affecting sheep? A. Haemonchus contortus B. Barber pole worm C. Wire worm D. Ring worm 116 Assessment 23. Ascaris is a common parasite found in which species? A. Horses B. Sheep C. Chickens D. Swine 24. Which of the following is NOT a common prevention method for parasitic diseases? A. Deworming at birth B. Good sanitation C. Contacting a veterinarian D. Isolating infected animals 117 Assessment 25. Which of the following is commonly known as roundworms? A. Ringworm B. Ascaris C. Barber pole D. Blackleg 118 Resources • Animal Disease Information. (2010). Retrieved from http://www.cfsph.iastate.edu • Pond, Wilson G. Pond, Kevin R.(2000). Introduction to Animal Science. John Wiley & Sons, Inc. • National Animal Disease Center.(2009). Retrieved from http://ars.usda.gov/ • United States Animal Health Report. (2008). Retrieved from http://www.aphis.usda.gov • Weaver, David Johne's Disease or Paratuberculosis. (2010). Retrieved from the http://extension.missouri.edu • Photos Courtesy of: – Dr. AP Knight, CSU Veterinary Extension – Dr. CV Kimberling, CSU Veterinary Extension – Tiffanie Brooks, D. V. M. Texas Tech University 119 Acknowledgements Collaborator: Tiffanie Brooks, D.V.M. Production Coordinator: Amber Krause Project Coordinator: Meghan Williams Graphic Designer: Melody Rowell Production Manager: Maggie Bigham V.P. of Brand Management Clayton Franklin Executive Producers: Gordon W. Davis, Ph.D. © MMXIV CEV Multimedia, Ltd. 120