Mind-Body Medicine Tara Saenz Learning Objectives 1. Define mind-body medicine. 2. According to the national survey, what are the most common mind-body medicine techniques (besides prayer) used by adults in the U.S.? 3. Why is the western world less accepting of mind-body medicine? 4. What occurred in the early 1900s that sparked an interest in the research of mind-body medicine? 5. What two positive outcomes of mindbody medicine interventions is there considerable evidence for? Introduction Mind-body medicine focuses on the interaction among the brain, mind, body, and behavior, and the powerful ways in which emotional, mental, spiritual, and behavioral factors can directly affect health. Mind-Body Medicine Techniques •Cognitive-behavioral therapies •Relaxation •Hypnosis •Imagery •Meditation •Yoga •Biofeedback •Tai Chi •Qigong •Group Support •Autogenic Training •Spirituality Prevalence • According to a national survey* in 2002: – 30% of adults in the U.S. were currently using one or more of the following mind-body medicine techniques: • • • • Relaxation Visual/Guided Imagery Biofeedback Hypnosis – 50% of adults in the U.S. were using prayer Wolsko PM, et al. Use of mind-body medical therapies. Journal of General Internal Medicine. 2004;19:43-50 Background • The concept of mind-body medicine dates back more than 2000 years – Integral to the healing approaches of traditional Chinese and Ayurvedic medicine – Hippocrates believed that treatment could only occur with the consideration of attitude, environmental influences, and natural remedies. The East vs. The West • The acceptance of mind-body medicine is divided between eastern and western cultures – The East still value the integrated approach of mind-body medicine – Beginning in the 16th and 17th centuries, the West began to separate the dimensions of the mind from the physical body • Redirection of Science • Technological Advances • Discovery of bacteria and antibiotics • Fixing or curing an illness became a matter of science and took precedence over the healing of the soul. Stress Response and Placebo Effect • Walter Cannon – “Fight or Flight” – Sympathetic and adrenal activation in response to perceived danger • Henry Beecher, M.D. – Placebo Effect – Low supply of morphine during WWII – Found that pain could be controlled by saline injections • As a result, since the 1960s, mind-body interactions have become an extensively researched field. Focus of Research • Mind-Body Interventions and Disease Outcomes – – – – The treatment of disease Decrease pain Improve mood, QOL, and coping Improve disease or treatment related symptoms • Mind-Body Influences on Immunity – Positive and negative effects of emotions on people’s susceptibility to infection • Meditation and Imaging – Use of fMRI to investigate the effects of meditation on the activation of regions of the brain • Placebo Response – Cognitive and conditioning mechanisms • Stress and Wound Healing – Positive and negative effects of mood or stress on the rate of wound healing • Surgical Preparation – Reduce discomfort and adverse effects Study #1 The evaluation of mind/body intervention to reduce psychological distress and perceived stress in college students Journal of American College Health 2002;50:281-287 Study #1 • Specific Aim – The effectiveness of a mind-body intervention on psychological distress and perceived stress in college students • Study Design – Randomized, placebo-controlled • Subjects – – – – – 128 college students 25% freshman/sophomores 41% junior/seniors 34% graduate students Median age = 21 years old Study #1 • Treatment – Six 90-minute group-training sessions Study #1 • Outcome Measures – Symptom Checklist-90-Revised – Spielberger State-Trait Anxiety Inventory – Perceived Stress Scale – Health-Promoting Lifestyle Profile II – A demographic and health habits survey Study #1 • Results – 90 students completed the postassessment measure – Significantly greater reductions in psychological distress, state anxiety, and perceived stress were found in the experimental group Study #1 • Conclusions – A 6-week RR and CBI training program for students can significantly reduce self-reported psychological distress, anxiety, and the perception of stress. – Found a trend toward improvements for the intervention group on trait anxiety and health-promoting lifestyle profiles. Study #2 Efficacy of ‘functional relaxation’ in comparison to terbutaline and a ‘placebo relaxation’ method in patients with acute asthma Psychotherapy and Psychosomatics 2001;70:151-157 Study #2 • Specific Aim – The effectiveness of functional relaxation (FR) on pulmonary function in patients with acute asthma in comparison to inhaled terbutaline (IT) and a placebo relaxation technique (PRT) • Study Design – Randomized, prospective, single-blind, placebo-controlled, crossover experimental investigation • Subjects – 21 asthmatics with acute bronchoconstriction – 7 male; 14 female – Average age: 48.9 years Study #2 • Treatment – On 3 consecutive days they were given either: • A 5-minute verbal standard instruction in elementary exercises of FR, which they were to practice during subsequent body plethysmographic measurement • IT (a fast-acting bronchodilator) • An unspecific PRT – Each subjects tried all 3 treatments in random order Study #2 • Outcome Measures – Standard pulmonary function measurements measured by a body plethysmograph Study #2 • Results – There was a significant decrease in specific airway resistance with FR, which was not as pronounced as IT, but it was significantly greater than with the PRT Study #2 • Conclusions – This study shows that clinically relevant effects can be achieved for patients with asthma through mindbody interaction, which can be triggered by reproducible procedures – Further development of the FR approach could lead to a nonpharmacological and effective supplementary treatment for asthma Other Evidence • Evidence from randomized controlled trials and systematic reviews of the literature suggest: – Mechanisms may exist by which the brain and central nervous system influence immune, endocrine, and autonomic functioning, which is known to have an impact on health. – Multi-component mind-body interventions may be appropriate adjunctive treatments for coronary artery disease and certain pain-related disorders, such as arthritis. Continued – Multimodal mind-body approaches, such as cognitive-behavioral therapy, can be effective adjuncts in the management of chronic conditions – An array of mind-body therapies when employed pre-surgically, may improve recovery time and reduce pain following surgical procedures. – Neurochemical and anatomical bases may exist for some of the effects of mind-body approaches. Summary & Recommendations • Considerable evidence that mindbody interventions have positive effects on psychological functioning and QOL • Physical and emotional risks are minimal • Mind-body interventions can be taught easily • Mind-body medicine should be used in conjunction with modern medicine as a combined approach to improving health Questions?