Human Anatomy & Physiology Chapter 1: Introduction Panda Wilson 1 II. Introduction A. The beginnings of the study of human anatomy and physiology were most likely concerned with treating illnesses and injuries that interrupted a person’s ability to function. B. Early healers began by relying heavily on superstition & magic. But, as they begin to try to heal their patients, they observed the effects of injuries and how wounds healed. Their observations & investigations would have included examining the bodies of the dead. Certain potions & herbs were discovered that could be used to treat common symptoms of illnesses. So observation led to experimentation – TA DA – modern science! Panda Wilson 2 III. Anatomy & Physiology Useful Information • Anatomy deals with the structure (morphology) of the body and its parts. • Physiology studies the functions of these parts • Anatomists rely on observation while physiologists employ experimentation • Function of a part depends on construction Panda Wilson 3 III. Anatomy & Physiology Anatomy (structure) is related to Physiology (function): A. The function of the hand is to grasp & manipulate objects of various sizes: • the structure of the fingers allow flexion & extension, enabling them to wrap around an object in order to grasp it • the joints of the thumb allow rotation as well as flexion & extension permitting the thumb to oppose the other fingers; this allows a pincer grasp B. New discoveries are more likely in physiology since it depends more on the development of scientific disciplines such as biochemistry and molecular sciences. Panda Wilson 4 IV. Levels of Organization Panda Wilson 5 V. 1.3 Characteristics of Life A. The following are characteristics shared by all organisms: • Movement – change in the position of the body or of a body part; may be internal or gross • Responsiveness – reaction to an external or internal change • Growth - an increase in body size without a change in shape • Reproduction – production of new cells or new organisms • Respiration – to obtain oxygen (O2), to release carbon dioxide (CO2), and to release energy from food • Digestion – to break down food substances into simpler forms that can be absorbed & used Panda Wilson 6 V. 1.3 Characteristics of Life A. The following are characteristics shared by all organisms: • Absorption – to move substances through membranes and into body fluids • Assimilation – to change absorbed substances into chemically different forms • Circulation – to move substances from place-to-place in body fluids • Excretion – to remove wastes produced by metabolic reactions B. Metabolism Panda Wilson 7 V. 1.3 Characteristics of Life B. Metabolism is the sum total of chemical reactions in the body. Includes reactions that breakdown substances (catabolism) and those that build substances (anabolism). Panda Wilson 8 VI. Maintenance of Life A. Life depends on the availability (quantity & quality) of the following 1. Water is required for metabolic reactions, for transport of substances, for temperature regulation 2. Food supplies nutrients necessary for energy and raw materials for building new living matter 3. Oxygen is used in chemical reactions that release energy from nutrients 4. Heat is a by-product of metabolism; its presence governs the rate at which reactions occur 5. Pressure is a compressing force required to facilitate movement of air or fluids Panda Wilson 9 VI. Maintenance of Life B. Vital signs (temperature, pulse, respiration, & blood pressure) indicate that a person is alive. Vital signs can also be helpful in forming a diagnosis on a patient. Panda Wilson 10 VI. Maintenance of Life C. Homeostasis 1. Maintenance of a stable internal environment is called homeostasis. • Receptors provide information about the internal environment • A set point is the value to be maintained • Effectors produce changes necessary to maintain the set point value Panda Wilson 11 VI. Maintenance of Life C. Homeostasis 2. The set point for a human’s body temperature is 98.6°F. • If body temperature falls below the set point receptors sense the drop in temperature and effectors are stimulated to increase metabolic processes so that more heat is produced until the body temperature reaches the set point. • If body temperature increases above the set point receptors sense the elevation in temperature and effectors are stimulated to increase vasodilation (blood moves to the surface of the skin and heat is lost to the environment, body temperature falls) and sweat glands are stimulated to produce sweat (evaporation of sweat from the skin's surface causes an additional drop in temperature). Panda Wilson 12 VI. Maintenance of Life C. Homeostasis 3. Negative feedback vs Positive feedback • In a negative feedback system, the deviation from the set point causes a response which leads to a return to the set point (reducing the difference / deviation between the set point & the actual condition of the body) for example: body temperature • A positive feedback system causes the deviation between set point and actual to increase. For example: nursing an infant – a loss of milk to a nursing infant leads to an increase in milk production Panda Wilson 13 VII. Organization of the Human Body Axial vs Appendicular: • The appendicular portion of the human body consists of the appendages: upper & lower limbs (arms & legs) • The axial portion of the human body includes the head, neck, & trunk. Panda Wilson 14 VII. Organization of the Human Body A. The axial portion of the body contains 4 major cavities and 4 smaller cavities of the head. 4 Major Cavities: 1. Cranial cavity – contains the skull / brain 2. Vertebral canal which contains the spinal cord & the vertebrae 3. Thoracic cavity – contains the heart & lungs 4. Abdominopelvic cavity – which is further divided into an upper abdominal cavity and a lower pelvic cavity Panda Wilson 15 The Axial Portion of the Human Body Panda Wilson 16 VII. Organization of the Human Body B. 1. The thoracic cavity • is divided by the mediastinum into right and left cavities which contain the right & left lungs; • the mediastinum contains the heart, esophagus, trachea, & the thymus gland. • The thoracic cavity is separated from the abdominopelvic cavity by a broad, thin muscle called the diaphragm. Panda Wilson 17 VII. Organization of the Human Body B. 2. The abdominopelvic cavity • The upper abdominal cavity contains the following viscera: stomach, liver, gallbladder, kidneys, and most of the small & large intestines • The lower pelvic cavity contains the following viscera: the terminal portions of the large intestines, urinary bladder, and internal reproductive organs Panda Wilson 18 VII. Organization of the Human Body C. The four smaller cavities of the body are found in the head: 1. Oral cavity – contains the teeth & tongue 2. Nasal cavity - within the nose; contain the sinuses (air-filled chambers); 3. Orbital cavities – contain the eyes and associated skeletal muscles & nerves; 4. Middle ear cavities – contain the middle ear bones. Panda Wilson 19 VII. Organization of the Human Body D. Thoracic & Abdominopelvic Membranes Parietal membrane refers to membranes attached to the wall of a cavity. Visceral membrane refers to the deeper membrane that covers an internal organ Panda Wilson 20 VII. Organization of the Human Body D. Thoracic & Abdominopelvic Membranes 1. Membranes of the thoracic cavity are called pleura: a. The walls of the thoracic cavity are lined with membranes referred to as the parietal pleura. b. The lungs are covered by visceral pleura. c. The parietal & visceral pleura are separated by a “potential” space called the pleural cavity (there is no actual space because the area is filled with a thin, watery fluid called the serous fluid) Panda Wilson 21 VII. Organization of the Human Body D. Thoracic & Abdominopelvic Membranes 2. The heart is located in the mediastinum of the thoracic cavity and is surrounded by pericardial membranes. • The walls of the mediastinum is covered by a thick parietal pericardium; • The surface of the heart is covered by a thinner visceral pericardium. • The parietal & visceral pericardium are separated by a “potential” space called the pericardial cavity that contains small amount of serous fluid Panda Wilson 22 VII. Organization of the Human Body D. Thoracic & Abdominopelvic Membranes 3. In the abdominopelvic cavity the lining membranes are called peritoneal membranes. • A parietal peritoneum lines the walls of the cavity • The surface of each organ is covered by a visceral peritoneum. • The parietal & visceral peritoneum are separated by a “potential” space called the peritoneal cavity Panda Wilson 23 VII. Organization of the Human Body E. Organ systems 1.Integumentary system 2. Skeletal system 3. Muscular system 4. Nervous system 5. Endocrine system 6. Cardiovascular system 7. Lymphatic system, 8. Digestive system 9. Respiratory system 10. Urinary system 11.Reproductive system Panda Wilson 24 Integumentary System Function: Body Covering Body Covering The integumentary system (including skin, hair, nails, and various glands): • covers the body, • senses changes outside the body, • and helps regulate body temperature. Panda Wilson 25 Skeletal & Muscular System Function: Support & Movement a. The skeletal system is made up of bones and ligaments. It supports, protects, provides frameworks, stores inorganic salts, and houses blood-forming tissues; b. The muscular system consists of the muscles that cause body movement, maintain posture, and is the main source of body heat. Panda Wilson 26 Nervous & Endocrine System Function: Integration & Coordination a. The nervous system consists of the brain, spinal cord, nerves, and sense organs. It integrates incoming information from receptors and sends impulses to muscles and glands. (Sense & Respond) b. The endocrine system (including all of the glands that secrete hormones), helps to integrate metabolic functions by secreting chemical messengers called hormones. Panda Wilson 27 Cardiovascular& Lymphatic System Function: Transport a. The cardiovascular system, made up of the heart and blood vessels, distributes oxygen and nutrients throughout the body while removing wastes from the cells. b. The lymphatic system, consisting of lymphatic vessels, lymph nodes, thymus, and spleen, drains excess tissue fluid and includes cells of immunity that help protect the body from pathogens. Panda Wilson 28 Digestive, Respiratory, & Urinary System Function: Absorption & Excretion a. The digestive system is made up of the mouth, esophagus, stomach, intestines, and accessory organs. It receives food, breaks it down, absorbs nutrients, & excretes waste. b. The respiratory system (lungs, respiratory passages, nose, & pharynx) exchanges gases between the blood & air. c. The urinary system (consisting of the kidneys, ureters, bladder, & urethra) removes wastes from the blood and helps to maintain fluid and electrolyte balances. Panda Wilson 29 Reproductive System Function: Reproduction The reproductive system produces new organisms. a. The male reproductive system consists of the testes, accessory organs, and vessels that produce sperm & conduct it to the penis. b. The female reproductive system consists of ovaries, uterine tubes, uterus, vagina, and external genitalia. The female reproductive system produces ova & also houses the developing offspring. Panda Wilson 30 Anatomical Terminology • Relative Positions: 1. Terms of relative position are used to describe the location of a part relative to another part. 2. Terms of relative position include: • superior, inferior, anterior, posterior, medial, lateral, proximal, distal, superficial (peripheral), and deep. Panda Wilson 31 Body Sections 1. A sagittal section divides the body into right & left portions. 2. A transverse section divides the body into superior & inferior portions. It is often called a “cross section”. 3. A coronal section divides the body into anterior & posterior sections. Panda Wilson 32 CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. Body Sections, cont Sometimes a cylindrical organ (a long bone, the trachea), in such cases: 1. A cut across the structure is called a cross-section. 2. An angular cut across the structure is called an oblique section. 3. A lengthwise cut on the structure is called a longitudinal section. Panda Wilson 34 CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. • Body Regions 1. The abdominal area can be divided into nine regions. 2. Terms used to refer to various body regions are depicted in Fig. 1.15.