Physiological Psychology – Module 3 Genetic Influences – Module 5 General Psych 2 Februaty 3, 2004 Class #3 Biological Roots of Behavior Franz Gall (1758-1828) – Austrian physicist who invented phrenology He felt that bumps on the skull could reveal our mental abilities and character traits Introduced as being scientific but its use was exploited by quacks on gullible individuals Phrenology Became similar to that of astrology, palmreading and tarot Although, ill-fated theory was laughed at by scientific community of that day – it may have had some validity Localization of brain functions somehow hit the mark The Nervous System Electrochemical communication system that enables us to think, feel, and behave Complex beyond comprehension Although, human brains are more complex our nervous systems and those of animals operate in a similar fashion Allows researchers to study simple animals such as squids and sea slugs to help us better understand the organization of our own brains Advantage of this is experimentation Divisions of the Nervous System Consists of two systems Central Nervous System (CNS) (brain and spinal cord) Peripheral Nervous System (PNS) which connects the CNS to the rest of the body Organization of the Nervous System Peripheral Nervous System Two components: Somatic Nervous System Transmits sensory input to the CNS from the outside world and directs motor output Autonomic Nervous System Controls glands and muscles of our internal organs “automatic pilot” Autonomic Nervous System Dual system: Sympathetic Nervous System Arouses the body Parasympathetic Nervous System Calms us down Neurons Nerve cells (building blocks) Ours are essentially identical to animals Small samples of brain tissue from a person and a monkey are basically indistinguishable Neural Communication How does a neuron communicate with other cells to influence our behavior? In a complicated process a neuron fires an impulse when it receives signals from sense receptors… The impulse is called the action potential which is a brief electrical charge that travels down the axon which pass messages away from the cell body to other neurons, muscles, or glands Neurons are like batteries in that they generate electricity from chemical events This process involves the exchange of electrically charged atoms called ions Neural Communication When the action potential reaches the terminals at an axon’s end, it triggers the release of chemical messengers (neurotransmitters) some of which are then sent to different parts of the brain while others are reabsorbed by the sending neuron in a process called reuptake See pages 46-49 in the text for a more detailed description of this process Neurotransmitters Neurotransmitters are chemicals made by neurons and used by them to transmit signals to the other neurons A chemical message telling the next cell to fire or not to fire its own action potential More than 200 in our body all with different functions Lets briefly discuss some of the most important ones… Serotonin Facilitates a relaxed, sleepy feeling Tryptophan which is an amino acid found in dairy products and turkey is converted into serotonin in the body So, insomnia sufferers may be smart to listen to grandmother’s suggestion to drink a warm glass of milk before going to bed Some Illnesses Associated With Serotonin Too low levels in depression and anxiety sufferers Obesity may also be associated with low levels Linked to aggression as well -- low levels in the brains of suicide victims Dopamine High levels lead to pleasure Makes person feel happy and active Dopamine raises the body's temperature and increases metabolic rate Gives you euphoric feelings and allows you to be active Drug and alcohol abuse will block dopamine receptors and therefore a person needs to take more to get the same effect Illnesses Associated With Dopamine Parkinson’s Disease – too low levels Schizophrenia – too high levels Tourette’s disorder – too high levels Huntington’s disease – too high levels Norepinephrine Plays a role in attention and arousal Used by sympathetic nervous system to prepare us for action Illnesses Associated With Norepinephrine Depression Chronic stress depletes this neurotransmitter and can lead to depression Note: Aerobic Exercise is found to protect the brain from this depletion – so go out and run a mile or two if your down in the dumps Epinephrine Involved in energy and glucose metabolism Illnesses Associated With Epinephrine Depression – too low levels Acetylcholine Involved in voluntary movement, learning, memory, and sleep Helps parasympathetic nervous system to slow our heart rate Illnesses Associated With Acetylcholine Alzheimer’s disease – too low levels Note: Unfortunately, drugs used to increase acetylcholine to help restore normal levels appear to have small effects on improving memory GABA Inhibits excitation and anxiety Appears directly related to anxiety reduction Illnesses Associated With GABA Anxiety disorders – too low levels Huntington’s Disease – too low levels GABA systems aren’t working and this allows dopamine systems to run wild Huntington's disease is a hereditary disorder characterized by memory loss, abnormal movement and premature death It affects 1 in 10,000 people, and children with an affected parent have a 50 percent chance of developing the disease Epilepsy – too low levels Glutamate Main excitatory neurotransmitter in the brain Very important in learning and memory Illnesses Associated With Glutamate Alzheimer’s disease Strokes Too low levels in hippocampus Too high levels can cause neurons to die ALS (Lou Gehrig’s Disease) Causes death in neurons in the spinal cord and brainstem Endorphins Involved in pain reduction and pleasure They enhance the release of dopamine These natural opiates are released in response to pain and vigorous exercise Illnesses Associated With Endorphins Use of artificial opiates can cause body to stop manufacturing its own – this can lead to drug addiction Endocrine System: Taking the Slow Lane Unlike the speedy nervous system which zips messages from eyes to brain to hand in a fraction of a second, endocrine messages use the slow lane May take several seconds or more as bloodstream carries a hormone from an endocrine gland to its target tissue Endocrine System Hormones are chemical messengers Influence all aspects of our lives – growth, metabolism, reproduction, moods, etc. Strives for homeostasis (balance) by responding to stress, exertion, internal thoughts, etc. Module 5: Genetic influences What influences one’s behavior: Nature or Nurture? The age-old debate: Is it genes or is it the environment? Principle of Genetics 23 chromosomes carried in the egg are paired with 23 chromosomes brought to it by the sperm 46 chromosomes – master plan for your body Each is composed of a molecule called DNA DNA is made up of thousands of segments which are called genes Principle of Genetics Your sex is determined by the 23rd pair – the sex chromosomes From your mother always an “x” From your father, you have a 50/50 chance of receiving an x making you a female From your father, you have a 50/50 chance of receiving an xy making you a male XX = female XY = male Twin Studies Monozygotic: identical twins (one-egg) Dizygotic: not identical – resemble one another as much as any brother or sister would. Question: Do identical twins who are adopted by separate families act like one another more than say two adopted children into the same family who have no genetic influences? “The Jim Twins” Thomas Bouchard’s University of Minnesota twin studies – extraordinary similarities between Jim Springer and Jim Lewis (Bouchard, 1979) Uncanny coincidences? Any limitations to this study? Bouchard (1979) Oskar Stohl and Jack Yulfe were raised in environments with more obvious differences Adoption Studies Surprising finding from hundred’s of studies: people who grow up together, whether biologically related or not – DO NOT much resemble one another in personality… Adoptee’s more similar to biological parents than adoptive parents Developmental Psych’s big puzzle: Why are children in the same family so different???