Supplemental Tables
Predictors of adherence to safe handling practices for antineoplastic drugs: survey of hospital nurses
Sharon R. Silver
Division of Surveillance, Hazard Evaluation and Field Studies
National Institute for Occupational Safety and Health
1090 Tusculum Avenue, MS R-15
Cincinnati, Ohio 45226
U.S. ssilver@cdc.gov
(513) 841-4313
Andrea L. Steege
Division of Surveillance, Hazard Evaluation and Field Studies, National Institute for Occupational
Safety and Health, Cincinnati, Ohio, U.S.
James M. Boiano
Division of Surveillance, Hazard Evaluation and Field Studies, National Institute for Occupational
Safety and Health, Cincinnati, Ohio, U.S.
Keywords:
Healthcare; exposure controls; nurses; hospital; antineoplastic drugs
Word count: 3990

APPENDIX
Table A. Demographics and work characteristics, hospital nurses who administered antineoplastic drugs (ADs) during past week
Characteristic (n A )
Total
Sex (1094)
Male
Female
Race (1082) C
White
African American
Asian
Other
Hispanic ethnicity (1091)
Age – mean (standard deviation)
Education (1085)
High school grad/general equivalency diploma (GED)
Vocational certificate
Associate’s degree
Bachelor’s degree
Master’s degree
Doctoral or professional degree
Nursing level (1089)
Staff nurse (RN, LPN, LVN)
Advanced practice nurse (NP, CRNA, CNS, CNM)
Nursing specialty
Hematology/oncology nurse
Other
Paid (1092)
Salaried
Hourly/fee-for-service/other
Duration working for current employer (1094)
< 1 year
1–5 years
6–10 years
11–20 years
< 20 years
Duration in current occupation (1094)
< 1 year
1–5 years
6–10 years
11–20 years
20–30 years
>30 years
Duration administering ADs (1093)
< 1 year
1–5 years
6–10 years
11–20 years
>20 years
Location of primary place of employment (1093)
Large city (>=50,000 people)
Small city (<50,000 people)
Suburb
Rural
Number of employees at primary workplace (1093)
2–9
246 (22.5)
299 (27.3)
23 (2.1)
266 (24.3)
216 (19.7)
314 (28.7)
213 (19.5)
62 (5.7)
30 (2.7)
250 (22.9)
212 (19.4)
301 (27.5)
300 (27.4)
745 (68.2)
173 (15.8)
114 (10.4)
61 (5.6)
35 (3.2)
562 (51.8)
257 (23.7)
15 (1.4)
953 (87.5)
136 (12.5)
723 (66.1)
371 (33.9)
333 (30.5)
759 (69.5)
43 (4.1)
281 (25.7)
225 (20.6)
Number (% B )
1094 (100)
43 (3.9)
1051 (96.1)
978 (90.4)
42 (3.9)
60 (5.6)
15 (1.4)
34 (3.1)
49.0 (10.8)
3 (0.3)
8 (0.7)
240 (22.1)

10–99
100–249
250–1000
>1000
Type of employer (1094)
For-profit
87 (8.0)
52 (4.8)
319 (29.2)
800 (54.9)
179 (16.4)
Non-profit/not-for-profit
Local or federal government, public university, other
697 (63.7)
228 (20.8)
RN= registered nurse; LPN=licensed practical nurse; LVN=licensed vocational nurse; NP=nurse practitioner;
CRNA=certified registered nurse anesthetist; CNS=clinical nurse specialist
A Number of respondents varied for individual items (i.e., number of eligible respondents less number who elected not to answer).
B Percents may not total 100 exactly due to rounding.
C Percents may add to more than 100 because respondents could select more than one answer.

Table B. Work hours
Characteristic (n A )
# healthcare employers (1091)
1
2
3
>3
Percent of time spent in direct patient care (1093)
1–25%
1
2
3
26–50%
51–75%
76–100%
# days worked past week (1094)
Number (%
885 (81.1)
63 (5.8)
9 (0.8)
134 (12.3)
108 (9.9)
98 (9.0)
149 (13.6)
738 (67.5)
6 (0.6)
46 (4.2)
233 (21.3)
B )
4
5
6
7
Number of hours worked for primary employer during past week (1072) -- mean (standard deviation)
Worked overtime past week (1091)
Mandatory overtime last week (387)
Usual shift (1080)
Regular daytime/evening
Regular nights
Regular shift including on-call
Rotating shift
Split shift/irregular shift/other
Length of usual shift (1094)
< 8 hours
8 hours
9–10 hours
11–12 hours
>12 hours
300 (27.4)
455 (41.6)
45 (4.1)
9 (0.8)
40.6 (11.6)
336 (30.8)
51 (15.2 of those with overtime)
843 (78.0)
110 (10.2)
43 (4.0)
68 (6.3)
16 (1.5)
9 (0.8)
415 (37.9)
238 (21.8)
312 (28.5)
63 (5.8)
Variable number of hours/other 57 (5.2)
A Number of respondents varied for individual items (i.e., number of eligible respondents less number who elected not to answer).
B Percents may not total 100 exactly due to rounding.

Table C. Training in administration of antineoplastic drugs (ADs) and perception of work environment
Characteristic (n A )
Employer has procedures that address safe administration of ADs (1087)
Yes
No
Very familiar with guidance on administering ADs from at least one of four specified organizations: American Society of Health-System Pharmacists; the National Institute for
Occupational Safety and Health; the Oncology Nursing Society; the Occupational Safety and Health Administration (1094)
Yes
No
Ever trained in safe handling for administering ADs (1091)
Yes
No
Trained in safe handling for administering ADs during past year (1091)
Yes
Number (%
1042 (95.2)
52 (4.8)
850 (77.7)
244 (22.3)
1041 (95.4)
50 (4.6)
715 (65.5)
No
I usually have enough time to take safety precautions while completing my duties (1050)
376 (34.5)
Strongly agree 308 (29.4)
Agree
Disagree
Strongly disagree
Not applicable
Proper personal protective equipment is available to me (1054)
590 (56.4)
130 (12.4)
19 (1.8)
3 (0.3)
B )
Strongly agree
Agree
Disagree
Strongly disagree
Not applicable
I feel that there is adequate staffing to perform my job duties (1049)
Strongly agree
Agree
555 (52.7)
418 (39.7)
54 (5.1)
14 (1.3)
13 (1.3)
199 (19.0)
462 (44.0)
Disagree
Strongly disagree
295 (28.1)
92 (8.8)
Not applicable 1 (0.1)
A Number of respondents varied for individual items (i.e., number of eligible respondents less number who elected not to answer).
B Percents may not total 100 exactly due to rounding.

Table D. Characteristics of administration of antineoplastic drugs (ADs) and outcome variables
Characteristic (n A )
Total number of AD treatments administered past week (1090)
1–2
3–4
5–9
10–20
21–40
>40
Days administered ADs past week (1092)
1
2
3
4
5
6–7
Administered liquid ADs past 7 days (1086)
Yes
No
Of those administering liquid ADs
How received liquid ADs from pharmacy (1037)
IV tubing primed with ADs
IV tubing primed with diluents
IV tubing not primed
Not applicable (not received from pharmacy)
Of respondent priming tubing themselves (352), primed with
Antineoplastic agent
Diluents
Used a closed-system drug transfer device (1024)
Always
Sometimes
Never
Number (%
386 (35.4)
304 (27.9)
194 (17.8)
128 (11.8)
60 (5.5)
17 (1.6)
249 (22.8)
290 (26.6)
251 (23.0)
148 (13.6)
151 (13.8)
3 (0.3)
1045 (96.2)
41 (3.8)
124 (12.3)
607 (58.5)
274 (26.4)
32 (3.1)
58 (16.5)
307 (87.2)
494 (48.2)
60 (5.9)
470 (45.9)
B )
Used luer-lock fittings (1039)
Always
Sometimes
Never
Used needleless system (1037)
Always
Sometimes
Never
961 (92.7)
32 (3.1)
44 (4.2)
A Number of respondents varied for individual items (i.e., number of eligible respondents less number who elected not to answer).
B Percents may not total 100 exactly due to rounding.
984 (94.7)
20 (1.9)
35 (3.4)