Karyotypes The diagram below shows the karyotype of a normal human. Karyotypes are prepared from the nuclei of cultured white blood cells that are “frozen” at the metaphase stage of mitosis. They are matched up from the biggest chromosomes to the smallest. The bigger the chromosome the more information it carries. VOCAB: Nuclei-plural form of nucleus. Many nucleuses. Cultured cell-a living cell that scientists use in laboratories White Blood Cell-Cells that are part of the immune system. They protect you from infections. Vocab practice: Use each word in a separate ORIGINAL sentence 1. 2. 3. What is the purpose of mitosis?___________________________________________________________ Draw what a cell in metaphase looks like. Make sure to include centrioles, spindle fibers and chromosomes. Photographs of the chromosomes are arranged on a grid so that the homologous pairs are placed together. Homologous pairs are identified by their general shape, length and the pattern of banding produced by a special staining technique. VOCAB: Chromosome-Made of DNA tightly coiled together. Carries genetic information. Homologous pairs-Pairs of chromosomes that are the same size, shape, and carry the same genetic information Staining technique-A way for scientists to color only the parts of a cell that they are looking for, in this case, chromosomes. Vocab practice: Use each word in a separate ORIGINAL sentence 1. 2. 3. Karyotypes for a human male and female are shown below. The male karyotype has 44 autosomes, a single X chromosome and a Y chromosome (written 44 +XY), a female karyotype has 44 autosomes and 2 X chromosomes (written 44 + XX). VOCAB: Autosome-any chromosome that is NOT a sex chromosome. The first 22 pairs of chromosomes on a karyotype Label the 2 karyotypes as either male or female Circle the sex chromosomes Put a square around the homologous pairs of chromosomes Males have _________________autosomes and ________ are their sex chromosomes Females have________________autosomes and ________are their sex chromosomes 1. Explain what a karyotype is and what information you can find________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ Chromosome numbers for different species: Human Chimpanzee Gorilla Horse Goldfish Fruit Fly Potato 46 48 48 64 94 8 48