Module Five: Interactive Lesson: Storyboard
Katherine M. Wright
Grand Canyon University
TEC-542
March 12, 2011
The Cell Cycle
Picture of animal cell --
Picture of plant cell --
http://www.cellsalive.com/cells/cell_model.htm
http://www.cellsalive.com/cells/cell_model.htm
OR
How cells make new cells
(Sullivan, J. 2010)
Two major parts
of the cell cycle:
Interphase –
resting and growing
http://micro.magnet.fsu.edu/micro/gallery/
mitosis/mitosis.html
http://www.biology.arizona.edu/cell_bio/
activities/cell_cycle/cell_cycle.html
Mitosis –
dividing
(University of Arizona, 2005)
Interphase
usually lasts 10-30 hours in mammals
Three stages:
GAP 1 (G1) – growing
Cells increase in size, produce RNA and synthesize
proteins,
S Phase (S) – synthesizing Duplication of Chromosomes
or DNA, forming chromatids connected with centromere
http://education.kings.edu/dsmith/
Lesson%206.html
http://education.kings.edu/dsmith/Lesson%206.html
GAP 2 (G2) – checking
Cell continues to grow and synthesize proteins
at the end it double checks before starting mitosis
(Sullivan, J. 2010;
University of Arizona, 2005)
Cell Cycle Animation
http://www.cellsalive.com/cell_cycle.htm
(Sullivan, J. 2010)
Mitosis – cell division
Mitosis (M phase)
Shorter -- lasts 2-3 minutes in mammals
Growth and protein production stops
All cell’s energy is focused on the complex steps of cell division
End result is two similar (identical DNA) daughter cells
(Sullivan, J. 2010;
University of Arizona, 2005)
Go to
http://www.youtube.com/watch?v=3kpR5RSJ7SA&feature=related
http://movies-tigernathanielvladimir.blogspot.com/2011/03/cell-cycle-mitosis.html
Prophase – first phase
http://www.wpclipart.com/medical/anatomy
/cells/mitosis/Mitotic_Prophase.png.html
The nucleolus fades.
http://www.biology.arizona.edu/cell
_bio/tutorials/cell_cycle/cells3.html
Chromatin (replicated DNA and associated proteins) condenses into chromosomes. Each
replicated chromosome has two identical chromatids.
Microtubules of the cytoskeleton disassemble and centrioles move to opposite sides of
the cell
(during interphase are responsible for cell shape, motility and attachment to other cells)
The microtubules are grow the mitotic spindle from the region of the centrosomes to the
centrioles.
(Sullivan, J. 2010;
University of Arizona, 2005)
Prometaphase
http://www.wpclipart.com/medical/anatomy/ce
lls/mitosis/Mitotic_Prometaphase.png.html
http://www.biology.arizona.edu/cell
_bio/tutorials/cell_cycle/cells3.html
Nuclear membrane dissolves
Proteins attach to the centromeres creating the kinetochores.
Microtubules (spindle fibers) attach at the kinetochores and the chromosomes
begin moving.
Other Microtubules (spindle fibers) elongate but instead of attaching to
chromosomes, overlap each other at the cell center.
(Sullivan, J. 2010;
University of Arizona, 2005)
Metaphase
http://www.wpclipart.com/medical/anatomy
/cells/mitosis/Mitotic_Metaphase.png.html
http://www.biology.arizona.edu/cell
_bio/tutorials/cell_cycle/cells3.html
Spindle fibers align the chromosomes along the middle of the cell nucleus.
This line is referred to as the metaphase plate.
This organization helps to ensure that when the chromosomes are separated, each
new nucleus will receive one copy of each chromosome.
A check is conducted insuring that the cell is ready to complete cell division
(Sullivan, J. 2010;
University of Arizona, 2005)
Anaphase
http://www.wpclipart.com/medical/anatomy
/cells/mitosis/Mitotic_Anaphase.png.html
http://www.biology.arizona.edu/cell
_bio/tutorials/cell_cycle/cells3.html
Paired chromosomes separate at the kinetochores and move to opposite sides of the cell.
****Spindle fibers shorten
****Kinetochores separate
****Chromatids (daughter chromosomes) are pulled apart and begin moving to the cell
poles.
Motion results from a combination of kinetochore movement along the spindle
microtubules and through the physical interaction of polar microtubules.
(Sullivan, J. 2010;
University of Arizona, 2005)
Telophase
http://www.biology.arizona.edu/cell
_bio/tutorials/cell_cycle/cells3.html
http://www.wpclipart.com/medical/anatomy
/cells/mitosis/Mitotic_Telophase.png.html
Chromatids arrive at opposite poles of cell
New membranes form around the daughter nuclei
The chromosomes disperse and are no longer visible under the light microscope.
The spindle fibers disperse,
Cytokinesis (the division of the cell) may also begin during this stage.
(Sullivan, J. 2010;
University of Arizona, 2005)
Cytokinesis
http://www.wpclipart.com/medical/anatomy
/cells/mitosis/Mitotic_Cytokinesis.png.html
http://www.biology.arizona.edu/cell
_bio/tutorials/cell_cycle/cells3.html
Spindle fibers not attached to chromosomes begin breaking down (until only that
portion of overlap is left.
In this region a contractile ring cleaves the cell into two daughter cells.
Microtubules then reorganize into a new cytoskeleton for the return to interphase.
In plant cells, the rigid wall requires that a cell plate be synthesized between the
two daughter cells.
(Sullivan, J. 2010;
University of Arizona, 2005)
Mitosis
http://www.wpclipart.com/medical/anatomy/cells/mitosis/Mitosis_cells_sequence_large.jpg
Mitosis Animation
http://www.cellsalive.com/mitosis.htm
(Sullivan, J. 2010)
Let’s practice!!
Label the stages game -http://www.purposegames.com/
game/cell-mitosis-quiz/info
Control the stages game -http://nobelprize.org/educational/
medicine/2001/
For your viewing pleasure!
The Cell Rap-- here are the
lyrics, you add the tunes!!
http://bizzarroworld.homestead
.com/songs.html
These gals sing their hearts out -www.youtube.com/watch?v=sa0u
WNlqKyc&feature=related%20%20
Follow Bob on his most epic life journey-http://www.youtube.com/watch?v=2xeEd
n8EXyk&feature=related%20%20
Grading!
From the Website: Cellsalive -- http://www.cellsalive.com
Cells Alive Mitosis Crossword Puzzle -http://www.cellsalive.com/puzzles/mitosis/index.html
Complete Online quiz: http://quizstar.4teachers.org/ CRA
Biology classes -- The Cell Cycle Posttest
your grade will also be based on the application of this information in the Onion Root Tip
Lab, to be completed in the future.
http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/
cell_cycle.html
(You will need to identify the different stages of the cell cycle.)
References
Angier, Natalie (2002). Lesson 6: mitosis. Retrieved February 26, 2011
from: http://education.kings.edu/dsmith/Lesson%206.html
Davidson, Michael M. (2004) Molecular expressions. Retrieved February
26, 2011 from: The University of Florida
http://micro.magnet.fsu.edu/micro/gallery/mitosis/mitosis.html
Nobel Prize.Org. Games (2011) Control of the cell cycle. Retrieved
February 26, 2011 from: http://nobelprize.org/educational/medicine/2001/
RierroTheCoolest (2008) Cell mitosis game. Retrieved February 26, 2011
from: http://www.purposegames.com/game/cell-mitosis-quiz/info
Srokes, Ms. (2007) The cell cycle featuring: mitosis. Retrieved February
26, 2011 from:
http://www.youtube.com/watch?v=3kpR5RSJ7SA&feature=related
References
Sullivan, Jim. (2010) Cells alive. Retrieved February 26, 2011 from:
http://www.cellsalive.com/cells/cell_model.htm
The University of Arizona (2005). The Biology project. Retrieved
February 26, 2011 from:
http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/cell_cycle.
html
Valdimir, Nathanial (2011) The cell cycle mitosis. (Retrieved February
26, 2011 from: http://moviestigernathanielvladimir.blogspot.com/2011/03/cell-cycle-mitosis.html
WP Clipart (n.d.). Medical section: mitosis. Retrieved February 26,
2011 from: http://www.wpclipart.com/medical/anatomy/cells/mitosis/