Unit Lesson Plan – Gene Expression
Teacher:
Grade:
Subject:
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Time Frame:
12
15 days
School:
AP Biology
AP
Instructional Objective:
(condition, behavior, standard)
Instructional Objective:
(condition, behavior, standard)
Instructional Objective:
(condition, behavior, standard)
Instructional Objective:
(condition, behavior, standard)
Instructional Objective:
(condition, behavior, standard)
EK 2.C.1 Organisms use feedback mechanisms to maintain their internal
environments and respond to external environmental changes.
EK 3.A.1 DNA, and in some cases RNA, is the primary source of heritable
information.
EK 3.B.1 Gene regulation results in differential gene expression, leading to cell
specialization.
EK 4.A.3 Interactions between external stimuli and regulated gene expression result
in specialization of cells, tissues, and organs.
EK 4.C.2 Environmental factors influence the expression of the genotype in an
organism
Essential Questions
(What questions will the student be able to answer as a result of the instruction?)
1. What lead to the discovery of nucleic acids as the hereditary material of the cell?
2. How do cells insure all progeny have the same hereditary information?
3. How does the environment affect protein production in cells?
Knowledge & Skills
(What skills are needed to achieve the desired results?)
By the end of this unit, students can:
By the end of this unit, students will be able to:
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 LO 2.15 Justify a claim made about the effect(s) on a
biological system at the molecular, physiological, or
organismal level when given a scenario in which one
ore more components within a negative regulatory
system is altered. (SP 6.1)
 LO 2.16 Connect how organisms use negative
feedback to maintain their internal environments. (SP
7.2)
 LO 2.17 Evaluate data that show the effect(s) of
changes in concentration of key molecules on negative
feedback mechanisms. (SP 5.3)
 LO 2.18 Make predictions about how organisms use
negative feedback mechanisms to maintain their
internal environments. (SP 6.4)
 LO 2.19 Make predictions about how positive
feedback mechanisms amplify activities and processes
in organisms based on scientific theories and models.
(SP 6.4)
 LO 2.20 Justify that positive feedback mechanisms
amplify responses in organelles. (SP 6.1)
 LO 3.1 Construct scientific explanations that use the
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SP 1.2 Describe representations and models of
natural or man-made phenomena and systems in the
domain.
SP 1.3 Refine representations and models of natural
or man-made phenomena and systems in the domain.
SP 1.4 Use representations and models to analyze
situations or solve problems qualitatively and
quantitatively.
SP 4.1 Justify the selection of the kind of data needed
to answer a particular scientific question.
SP 5.3 Evaluate the evidence proved by data sets in
relation to a particular scientific question.
SP 6.1 Justify claims with evidence.
SP 6.2 Construct explanations of phenomena based
on evidence produced through scientific practices.
SP 6.4 Make claims and predictions about natural
phenomena based on scientific theories and models.
SP 7.2 Connect concepts in and across domain(s) to
generalize or extrapolate in and/or across enduring
understandings and/or big ideas.
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PSI AP Biology
Gene Expression
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structures and mechanisms of DNA and RNA to
support the claim that DNA and, in some cases, that
RNA are the primary sources of heritable information.
(SP 6.5)
LO 3.2 Justify the selection of data from historical
investigations that support the claim that DNA is the
source of heritable material. (SP 4.1)
LO 3.3 Describe representation and models that
illustrate how genetic information is copied for
transmission between generations. (SP 1.2)
LO 3.4 Describe representations and models
illustrating how genetic information is translated into
polypeptides. (SP 1.2)
LO 3.5 Justify the claim that humans can manipulate
heritable information by identifying at least two
commonly used technologies. (SP 6.4)
LO 3.6 Predict how a change in a specific DNA or
RNA sequence can result in changes in gene
expression. (SP 6.4)
LO 3.18 Describe the connection between regulation
of gene expression and observed differences
between different kinds of organisms. (SP 7.1)
LO 3.19 Describe the connection between regulation
of gene expression and observed difference between
individuals in a population. (SP 7.1)
LO 3.20 Explain how regulation of gene expression is
essential for the processes and structures that
support essential cell functions. (SP 6.2)
LO 3.21 Use representations to describe how gene
regulation influences cell products and functions. (SP
1.4)
LO 4.7 Refine representations to illustrate how
interactions between external stimuli and gene
expression result in specialization of cells, tissues,
and organs. (SP 1.3)
LO 4.23 Construct explanations of the influence of
environmental factors on the phenotype of an
organism. (SP 6.2)
LO 4.24 Predict the effects of a change in a
environmental factor on the genotypic expression of a
phenotype. (SP 6.4)
Assessment
(What is acceptable evidence to show desired results (rubrics, exam, etc.)? Attach Copy
During the Smart Notebook lesson designed to introduce concepts, students will be continually questioned on these
concepts using a combination of class work/homework questions and the SMART Response system. Classwork and
Homework questions will be discussed as a class and misconceptions will be addressed by the teacher prior to the
formal evaluations listed below.
Formative Evaluations:
Summative Evaluations:
Signal Transduction – Ethylene Activity
Discovery of DNA Quiz
Bacterial Transformation Lab
Replication & Gene Expression Quiz
Lab #8 Quiz
Unit Test
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PSI AP Biology
Gene Expression
(What is the sequence of activities, learning experiences, etc, that will lead to desired results (the plan)?
Topic
Classwork
Homework
1
Discovery of DNA
SMART Notebook Slides 426; Questions #1-4
#9-11
2
Discovery of DNA
SMART Notebook Slides
27-44; Questions #5-6
#12-13
3
Nucleic Acid Structure
SMART Notebook Slides
45-69; Questions #7-8
#14-15
4
Replication
Quiz 1: Discovery of DNA
SMART Notebook Slides
70-99; Questions #16-22
#23-29
5
Prokaryotic Gene
Expression - Transcription
SMART Notebook Slides
100-135; Questions #30-32
#40-42
6
Eukaryotic Gene
Expression - Transcription
SMART Notebook Slides
135-154; Questions #33-35
#43-45
7
Eukaryotic Gene
Expression - Translation
SMART Notebook Slides
155-180; Questions #36-39
#46-50
8
Signal Transduction Ethylene
Signal Transduction Activity
9
Recombinant DNA
Quiz 2: Gene Expression
SMART Notebook Slides
181-199; Questions #5153;
#54-56
Pre-Lab: Background
10 (lab)
Bacterial Transformation
Lab
Lab 8: Bacterial
Transformation
Analyzing Results
11
Bacterial Transformation
Lab
Lab 8: Calculations &
Evaluating Results
Experimental Design
12
Bacterial Transformation
Lab
Lab 8: Independent
Investigation
13
Bacterial Transformation
Lab
Lab 8: Independent
Investigation Analysis &
Discussion
Day
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Review for Lab Quiz
Gene Expression
14
Review
Lab 8 Quiz
MC/FR Review
MC/FR
15
Test
Test
MC/FR
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PSI AP Biology
Gene Expression