Water And The Major Minerals Copyright 2005 Wadsworth Group, a division of Thomson Learning Water And The Body Fluids • Functions of water: –Transport –Structural support for molecules –Participates in metabolic reactions –Solvent –Lubricant –Body temperature regulation –Maintains blood volume Copyright 2005 Wadsworth Group, a division of Thomson Learning Water And The Body Fluids • Water balance and recommended intakes –Intracellular fluid –Extracellular fluid •Interstitial fluid Copyright 2005 Wadsworth Group, a division of Thomson Learning One Cell And Its Associated Fluids Copyright 2005 Wadsworth Group, a division of Thomson Learning Water And The Body Fluids • Water balance and recommended intakes –Water intake •Dehydration •Water intoxication Copyright 2005 Wadsworth Group, a division of Thomson Learning Water And The Body Fluids • Water balance and recommended intakes –Water sources –Water losses –Water recommendations Copyright 2005 Wadsworth Group, a division of Thomson Learning • Water balance and recommended intakes –Health effects of water •Hard water vs. soft water •Bottled water Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning How The Body Regulates Blood Volume Copyright 2005 Wadsworth Group, a division of Thomson Learning Fluid And Electrolyte Balance • Dissociation of salt in water –Ions •Cations •Anions –Electrolyte solution Copyright 2005 Wadsworth Group, a division of Thomson Learning Water Dissolves Salts And Follows Electrolytes Copyright 2005 Wadsworth Group, a division of Thomson Learning Fluid And Electrolyte Balance • Electrolytes attract water • Water follows electrolytes –Solutes –Osmosis –Osmotic pressure Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning • Vegetables “sweat” when sprinkled with salt • Raisins plump up when immersed in water Fluid And Electrolyte Balance • Proteins regulate flow of fluids and ions • Regulation of fluid and electrolyte balance Copyright 2005 Wadsworth Group, a division of Thomson Learning Fluid And Electrolyte Imbalance • Sodium and chloride most easily lost • Different solutes lost by different routes Copyright 2005 Wadsworth Group, a division of Thomson Learning Fluid And Electrolyte Imbalance • Replacing lost fluids and electrolytes –Oral rehydration therapy (ORT) Copyright 2005 Wadsworth Group, a division of Thomson Learning Acid-Base Balance • pH Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Acid-Base Balance • Regulation by the buffers –Bicarbonate –Carbonic acid • Regulation by the lungs • Regulation by the kidneys Copyright 2005 Wadsworth Group, a division of Thomson Learning The Minerals An Overview The Minerals An Overview • Inorganic elements • The body’s handling of minerals Copyright 2005 Wadsworth Group, a division of Thomson Learning The Minerals An Overview • Variable bioavailability –Binders •Phytates •Oxalates Copyright 2005 Wadsworth Group, a division of Thomson Learning The Minerals An Overview • Nutrient interactions • Varied roles Copyright 2005 Wadsworth Group, a division of Thomson Learning Sodium • Roles in the body –Principal extracellular cation Copyright 2005 Wadsworth Group, a division of Thomson Learning Sodium • Hypertension –Salt sensitivity • Osteoporosis • Foods Copyright 2005 Wadsworth Group, a division of Thomson Learning Sodium Copyright 2005 Wadsworth Group, a division of Thomson Learning Sodium: In Summary • 1989 estimated minimum requirement for adults: 500 mg/day • Chief functions in the body – Maintains normal fluid and electrolyte balance – Assists in nerve impulse transmission and muscle contraction Copyright 2005 Wadsworth Group, a division of Thomson Learning Sodium: In Summary • Deficiency symptoms – Muscle cramps, mental apathy, loss of appetite • Toxicity symptoms – Edema, acute hypertension • Significant source – Table salt, soy sauce – Moderate amounts in meats, milks, breads, and vegetables – Large amounts in processed foods Copyright 2005 Wadsworth Group, a division of Thomson Learning Chloride • Chlorine (Cl2) vs. chloride ion (Cl-) • Roles in body –Principal extracellular anion Copyright 2005 Wadsworth Group, a division of Thomson Learning Chloride: In Summary • 1989 estimated minimum requirement for adults: 750 mg/day • Chief functions in the body – Maintains normal fluid and electrolyte balance – Part of hydrochloric acid found in the stomach, necessary for proper digestion Copyright 2005 Wadsworth Group, a division of Thomson Learning Chloride: In Summary • Deficiency symptoms – Do not occur under normal circumstances • Toxicity symptom – Vomiting • Significant sources – Table salt, soy sauce – Moderate amounts in meats, milks, eggs – Large amounts in processed foods Copyright 2005 Wadsworth Group, a division of Thomson Learning Potassium • Principal intracellular cation Copyright 2005 Wadsworth Group, a division of Thomson Learning Potassium: In Summary • 1989 estimated minimum requirement for adults: 2000 mg/day • Chief functions in the body – Maintains normal fluid and electrolyte balance – Facilitates many reactions – Supports cell integrity – Assists in nerve impulse transmission and muscle contractions Copyright 2005 Wadsworth Group, a division of Thomson Learning Potassium: In Summary • Deficiency symptoms – Muscular weakness – Paralysis – Confusion • Toxicity symptoms – Muscular weakness – Vomiting – If given into a vein, can stop the heart Copyright 2005 Wadsworth Group, a division of Thomson Learning Potassium: In Summary • Significant sources – All whole foods – Meats, milks, fruits, vegetables, grains, legumes Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium Balance Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium • Calcium rigor vs. calcium tetany Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium: In Summary • 1997 adequate intake (AI) –Adults 19-50 years: 100 mg/day –Adults 51 and older: 1200 mg/day • Upper level for adults: 2500 mg/day Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium: In Summary • Chief functions in the body –Mineralization of bones and teeth –Involved in muscle contraction and relaxation, nerve functioning, blood clotting –Blood pressure, immune defenses Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium: In Summary • Deficiency symptoms –Stunted growth in children –Bone loss (osteoporosis) in adults Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium: In Summary • Toxicity symptoms –Constipation –Increased risk of urinary stone formation and kidney dysfunction –Interference with absorption of other minerals Copyright 2005 Wadsworth Group, a division of Thomson Learning Calcium: In Summary • Significant sources –Milk and milk products –Small fish (with bones) –Tofu (bean curd), greens (broccoli, chard), legumes Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Phosphorus • 1997 RDA for adults: 700 mg/day • Upper level for adults (19-70 years): 4000 mg/day • Chief functions in the body –Mineralization of bones and teeth –Part of every cell –Important in genetic material, part of phospholipids Copyright 2005 Wadsworth Group, a division of Thomson Learning Phosphorus • Chief functions in the body (continued) –Used in energy transfer and in buffer systems that maintain acid-base balance • Deficiency symptoms –Muscular weakness, bone pain Copyright 2005 Wadsworth Group, a division of Thomson Learning Phosphorus • Toxicity symptoms –Calcification of nonskeletal tissues, particularly the kidneys • Significant sources –All animal tissues (meat, fish, poultry, eggs, milk) Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • Bone development and disintegration –Cortical bone –Trabecular bone Copyright 2005 Wadsworth Group, a division of Thomson Learning Healthy vs. Osteoporotic Trabecular Bones Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • Bone development and disintegration –Bone density Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • Age and bone calcium • Maximizing bone mass Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • Minimizing bone loss • Gender and hormones • Genetics and ethnicity Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • Physical activity and body weight • Smoking and alcohol Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • Dietary calcium is the key to prevention • Other nutrients play a supporting role Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium Copyright 2005 Wadsworth Group, a division of Thomson Learning Osteoporosis And Calcium • A perspective on supplements –Antacids –Bone meal –Oyster shell –Dolomite (limestone) Copyright 2005 Wadsworth Group, a division of Thomson Learning