Chapter 6 Opener Human blastocyst (at right) emerging from its zona pelucida Figure 6.1 An unfertilized ovum Figure 6.2 Maturation of sperm Figure 6.2 Maturation of sperm Figure 6.3 Fertilization and production of the conceptus Figure 6.3 Fertilization and production of the conceptus Figure 6.4 Development of the human conceptus Figure 6.5 Blastocyst in the process of implanting itself Figure 6.6 Stages of prenatal development Figure 6.7 Alfred Jost’s experiments on rabbits Figure 6.8 The genetic basis of sex determination Box 6.1 Biology of Sex: Atypical Development: Chromosomal Anomalies Figure 6.9 Sex determination Box 6.2 Biology of Sex: Atypical Development: Gonadal Intersexuality Figure 6.10 Migrating germ cells Figure 6.11 Development of the male and female reproductive tracts Figure 6.11 Development of the male and female reproductive tracts Box 6.3 Biology of Sex: Atypical Development: Androgen Insensitivity Syndrome Figure 6.12 Development of the male and female external genitalia Figure 6.12 Development of the male and female external genitalia (Part 1) Figure 6.12 Development of the male and female external genitalia (Part 2) Figure 6.12 Development of the male and female external genitalia (Part 3) Box 6.4 Biology of Sex: Atypical Development: Congenital Adrenal Hyperplasia Figure 6.13 Descent of the testes Figure 6.13 Descent of the testes Figure 6.13 Descent of the testes (Part 1) Figure 6.13 Descent of the testes (Part 2) Box 6.5 Biology of Sex: Atypical Development: 5α-Reductase Deficiency Box 6.6 Biology of Sex: Atypical Development: Hypospadias and Micropenis Figure 6.14 The third interstitial nucleus of the anterior hypothalamus (INAH3) Figure 6.15 Sexual differentiation in the hypothalamus Figure 6.15 Sexual differentiation in the hypothalamus Figure 6.16 Copulating rats Figure 6.17 Hormones and sexual behavior in rats Figure 6.17 Hormones and sexual behavior in rats Figure 6.18 When monkeys copulate, the male often grasps the feet or legs of the female with his own feet Photo, p. 177 1957 advertisement for DES in a medical journal Photo, p. 178 Because of variations in the timing of puberty, these 12-year-old girls vary a great deal in their physical development Figure 6.19 Growth velocity curves for boys and girls Figure 6.20 Typical development of pubic hair in girls at puberty Figure 6.21 Typical development of breasts in girls at puberty Figure 6.22 Puberty is starting earlier Figure 6.23 Typical development of male external genitalia at puberty Figure 6.24 Hormonal control of puberty Figure 6.24 Hormonal control of puberty Box 6.7 Biology of Sex: Atypical Development: Precocious and Delayed Puberty Figure 6.25 MRI slice through the human brain showing some of the regions whose size is affected by sex hormone levels at puberty Box 6.8 Personal Points of View: My Life with Androgen Insensitivity Syndrome