The Effect Size The effect size (ES) makes meta-analysis possible The ES encodes the selected research findings on a numeric scale There are many different types of ES measures, each suited to different research situations Each ES type may also have multiple methods of computation Practical Meta-Analysis -- D. B. Wilson 1 Examples of Different Types of Effect Sizes Standardized mean difference Odds-ratio Group contrast research Treatment groups Naturally occurring groups Inherently continuous construct Group contrast research Treatment groups Naturally occurring groups Inherently dichotomous construct Correlation coefficient Association between variables research Practical Meta-Analysis -- D. B. Wilson 2 Examples of Different Types of Effect Sizes Risk ratio Group differences research (naturally occurring groups) Commonly used by epidemiologist and medical meta-analyses Inherently dichotomous construct Easier to interpret than the odds-ratio Practical Meta-Analysis -- D. B. Wilson 3 Examples of Different Types of Effect Sizes Proportion Standardized gain score Central tendency research HIV/AIDS prevalence rates Proportion of homeless persons found to be alcohol abusers Gain or change between two measurement points on the same variable Reading speed before and after a reading improvement class Others? Practical Meta-Analysis -- D. B. Wilson 4 What Makes Something an Effect Size for Meta-analytic Purposes The type of ES must be comparable across the collection of studies of interest This is generally accomplished through standardization Must be able to calculate a standard error for that type of ES The standard error is needed to calculate the ES weights, called inverse variance weights (more on this latter) All meta-analytic analyses are weighted Practical Meta-Analysis -- D. B. Wilson 5 The Standardized Mean Difference X X G2 ES G1 s pooled s pooled s12 n1 1 s22 n2 1 n1 n2 2 Represents a standardized group contrast on an inherently continuous measure Uses the pooled standard deviation (some situations use control group standard deviation) Commonly called “d” or occasionally “g” Practical Meta-Analysis -- D. B. Wilson 6 The Correlation Coefficient ES r Represents the strength of association between two inherently continuous measures Generally reported directly as “r” (the Pearson product moment coefficient) Practical Meta-Analysis -- D. B. Wilson 7 The Odds-Ratio The odds-ratio is based on a 2 by 2 contingency table, such as the one below Frequencies Success Failure Treatment Group a b Control Group c d ad ES bc The Odds-Ratio is the odds of success in the treatment group relative to the odds of success in the control group. Practical Meta-Analysis -- D. B. Wilson 8 The Risk Ratio The risk ratio is also based on data from a 2 by 2 contingency table, and is the ratio of the probability of success (or failure) for each group a / ( a b) ES c / (c d ) Practical Meta-Analysis -- D. B. Wilson 9 Unstandardized Effect Size Metric If you are synthesizing are research domain that using a common measure across studies, you may wish to use an effect size that is unstandardized, such as a simple mean difference (e.g., dollars expended) Multi-site evaluations or evaluation contracted by a single granting agency Practical Meta-Analysis -- D. B. Wilson 10 Effect Size Decision Tree for Group Differences Research (Page 58 of Book) All dependent variables are inherently dichotomous Difference between proportions as ES [see Note 1] Group contrast on dependent variable Odds ratio; Log of the odds ratio as ES All dependent variables are inherently continuous All dependent variables measured on a continuous scale All studies involve same measure/scale Unstandardized mean difference ES Studies use different measures/scales Standardized mean difference ES Some dependent variables measured on a continuous scale, some artificially dichotomized Some dependent variables are inherently dichotomous, some are inherently continuous Practical Meta-Analysis -- D. B. Wilson Standardized mean difference ES; those involving dichotomies computed using probit [see Note 2] or arcsine [see Note 3] Do separate meta-analyses for dichotomous and continuous variables 11 Methods of Calculating the Standardized Mean Difference The standardized mean difference probably has more methods of calculation than any other effect size type See Appendix B of book for numerous formulas and methods. Practical Meta-Analysis -- D. B. Wilson 12 Degrees of Approximation to the ES Value Depending of Method of Computation Great Poor Good Direct calculation based on means and standard deviations Algebraically equivalent formulas (t-test) Exact probability value for a t-test Approximations based on continuous data (correlation coefficient) Estimates of the mean difference (adjusted means, regression B weight, gain score means) Estimates of the pooled standard deviation (gain score standard deviation, one-way ANOVA with 3 or more groups, ANCOVA) Approximations based on dichotomous data Practical Meta-Analysis -- D. B. Wilson 13 Methods of Calculating the Standardized Mean Difference Direction Calculation Method ES X1 X 2 X1 X 2 2 2 s pooled s1 (n1 1) s2 (n2 1) n1 n2 2 Practical Meta-Analysis -- D. B. Wilson 14 Methods of Calculating the Standardized Mean Difference Algebraically Equivalent Formulas: n1 n2 ES t n1n2 ES F (n1 n2 ) n1n2 independent t-test two-group one-way ANOVA exact p-values from a t-test or F-ratio can be converted into t-value and the above formula applied Practical Meta-Analysis -- D. B. Wilson 15 Methods of Calculating the Standardized Mean Difference A study may report a grouped frequency distribution from which you can calculate means and standard deviations and apply to direct calculation method. Practical Meta-Analysis -- D. B. Wilson 16 Methods of Calculating the Standardized Mean Difference Close Approximation Based on Continuous Data -Point-Biserial Correlation. For example, the correlation between treatment/no treatment and outcome measured on a continuous scale. ES 2r 1 r 2 Practical Meta-Analysis -- D. B. Wilson 17 Methods of Calculating the Standardized Mean Difference Estimates of the Numerator of ES -- The Mean Difference difference between gain scores difference between covariance adjusted means unstandardized regression coefficient for group membership Practical Meta-Analysis -- D. B. Wilson 18 Methods of Calculating the Standardized Mean Difference Estimates of the Denominator of ES -Pooled Standard Deviation s pooled se n 1 standard error of the mean Practical Meta-Analysis -- D. B. Wilson 19 Methods of Calculating the Standardized Mean Difference Estimates of the Denominator of ES -Pooled Standard Deviation s pooled MS between F MS between one-way ANOVA >2 groups 2 X j nj ( X j n j ) 2 k 1 Practical Meta-Analysis -- D. B. Wilson n j 20 Methods of Calculating the Standardized Mean Difference Estimates of the Denominator of ES -Pooled Standard Deviation s pooled s gain 2(1 r ) standard deviation of gain scores, where r is the correlation between pretest and posttest scores Practical Meta-Analysis -- D. B. Wilson 21 Methods of Calculating the Standardized Mean Difference Estimates of the Denominator of ES -Pooled Standard Deviation s pooled MS error df error 1 2 1 r df error 2 ANCOVA, where r is the correlation between the covariate and the DV Practical Meta-Analysis -- D. B. Wilson 22 Methods of Calculating the Standardized Mean Difference Estimates of the Denominator of ES -Pooled Standard Deviation s pooled SS B SS AB SSW df B df AB dfW A two-way factorial ANOVA where B is the irrelevant factor and AB is the interaction between the irrelevant factor and group membership (factor A). Practical Meta-Analysis -- D. B. Wilson 23 Methods of Calculating the Standardized Mean Difference Approximations Based on Dichotomous Data ES probit ( p group1 ) probit ( p group2 ) the difference between the probits transformation of the proportion successful in each group converts proportion into a z-value Practical Meta-Analysis -- D. B. Wilson 24 Methods of Calculating the Standardized Mean Difference Approximations Based on Dichotomous Data ES 3 log Odds ratio this represents the rescaling of the logged odds-ratio (see Sanchez-Meca et al 2004 Psychological Methods article) Practical Meta-Analysis -- D. B. Wilson 25 Methods of Calculating the Standardized Mean Difference Approximations Based on Dichotomous Data 2 ES 2 N 2 ES 2r 1 r 2 chi-square must be based on a 2 by 2 contingency table (i.e., have only 1 df) phi coefficient Practical Meta-Analysis -- D. B. Wilson 26 Practical Meta-Analysis -- D. B. Wilson 27 Practical Meta-Analysis -- D. B. Wilson 28 Formulas for the Correlation Coefficient Results typically reported directly as a correlation Any data for which you can calculate a standardized mean difference effect size, you can also calculate a correlation type effect size See appendix B for formulas Practical Meta-Analysis -- D. B. Wilson 29 Formulas for the Odds Ratio Results typically reported in one of three forms: Frequency of successes in each group Proportion of successes in each group 2 by 2 contingency table Appendix B provides formulas for each situation Practical Meta-Analysis -- D. B. Wilson 30 Data to Code Along With the ES The effect size May want to code the data from which the ES is calculated Confidence in ES calculation Method of calculation Any additional data needed for calculation of the inverse variance weight Sample size ES specific attrition Construct measured Point in time when variable measured Reliability of measure Type of statistical test used Practical Meta-Analysis -- D. B. Wilson 31 Issues in Coding Effect Sizes Which formula to use when data are available for multiple formulas Multiple documents/publications reporting the same data (not always in agreement) How much guessing should be allowed sample size is important but may not be presented for both groups some numbers matter more than others Practical Meta-Analysis -- D. B. Wilson 32