Cell Division GOAL: To make cells w/ SAME amount of DNA 46 1. Interphase Cell copies DNA 92 2. Mitosis 46 Divides DNA Equally 46 3. Cytokinesis 46 Cytoplasm divides/Cell splits 46 BIG PICTURE: Cell Division of Human Cells Why do cells divide? To create new life: zygote divides to become ball of cells Why do cells divide? Rarely divides To replace old cells: Different cells divided at different rates Divides once/day How fast do Cells divide? Never divides Divides once/year Rarely divides Why do cells divide? To help an organism grow: adding cells makes organism bigger Why do cells divide? To heal from injury: new cells fill in to help repair Learning Terms Thin/Stringy DNA seen in interphase Tightly coiled DNA Seen in mitosis Exact copies centromere Chromatin Chromosome Duplicated Chromosome Interphase THINK! – What 2 things happen during interphase? Cell grows Cell copies (doubles) its DNA Mitosis (4 Phases) The cell divides the DNA molecules equally THINK! – A mosquito normally has 6 DNA molecules. How many molecules will each cell have after mitosis? 6 THINK! – Humans normally have 46 DNA molecules. How many molecules will each cell have after mitosis? 46 Phase 1: Prophase (P= Prepare) Chromatin coils into chromosomes Nucleus disappears Spindle fibers appear Phase 2: Metaphase (M= Middle) Spindle fibers move the duplicated chromosomes into the middle of the cell Phase 3: Anaphase (A=Apart) Duplicated chromosomes split at the centromere Spindle fibers pull chromosomes to opposite sides of the cell Phase 4: Telophase (T= Tear/Two Nuclei) Chromosomes uncoil into chromatin Nucleus reappears Spindle fibers disappear Cytokinesis THINK! – What happens? Cytoplasm and organelles divided (cell splits) Cytokinesis: Animal vs. Plant Animal Cells Cell membrane pinches inward Plant Cells Hard Cell plate forms in center Visualizing Mitosis! ACTIVITY INTERACTIVE ACTIVITY TO TRY WITH THE CLASS! Mitosis Hybrid Medical Animation http://hybridmedicalanimation.com/anim_mitosis.html Mitosis with Music http://www.loci.wisc.edu/outreach/bioclips/CDBio.html Brain-Pop Clip (Mitosis) http://glencoe.mcgraw-hill.com/sites/007877800x/student_view0/brainpop_movies.html# Streaming Animations Glencoe Mitosis Animation United Streaming (Mitosis_ 1:18) Real-Time Animations Animal Cell Mitosis (Just click on “LIVE ANIMAL MITOSIS”) http://iknow.net/CDROMs/cell_cdrom/index.html Plant Cell Mitosis (Just click on “PLANT CELL MITOSIS”) http://iknow.net/CDROMs/cell_cdrom/index.html Helpful Websites Cells Alive - http://www.cellsalive.com/mitosis.htm Biology Corner http://www.biologycorner.com/bio1/cellcycle.html