Breast Cancer Screening Guidelines Across Canada Environmental Scan July 2015 July 2015 Background • Quarterly, the Canadian Partnership Against Cancer collects information from the provinces/territories and international organizations on the status of population-based breast cancer screening programs and/or strategies. • This information compares current guidelines and evidence-based recommendations in order to identify leading practices. July 2015 Presentation Outline Canadian Task Force on Preventive Health Care Guidelines Provincial and Territorial Screening Guidelines Breast Cancer Screening Programs in Canada Recall Following a Normal Mammogram High Breast Density Recommendations High Risk Screening Guidelines (Breast MRI) Quality Assurance Measures July 2015 Canadian Task Force on Preventive Health Care Guidelines The Canadian Task Force on Preventive Health Care (2011) recommends the following for breast cancer screening amongst average risk women: Mammography • For women aged 40-49, routine screening not recommended (Weak recommendation; moderate quality evidence) • For women aged 50-69, routine screening every 2 to 3 years (Weak recommendation; moderate quality evidence) • For women aged 70-74, routine screening every 2 to 3 years (Weak recommendation; low quality evidence) Magnetic Resonance Imaging • Routine screening not recommended (Weak recommendation; no evidence) July 2015 Canadian Task Force on Preventive Health Care Guidelines, cont’d Clinical Breast Exam • Routine screening for breast cancer is not recommended when performing clinical breast exam alone or in conjunction with mammography (Weak recommendation; low quality evidence) Breast Self Exam • Routine practice of breast self exam is not advised by the Task Force (Weak recommendation; moderate quality evidence) For more information please visit: http://canadiantaskforce.ca/ July 2015 Breast Cancer Screening Programs: Provincial and Territorial Clinical Practice Guidelines For asymptomatic women at average risk: Start Age Nunavut* Interval Stop Age Current guidelines under review Begin at age 50 (age 40 – 49 accepted by physician referral for initial screen but not actively recruited) For women aged 40-49 – annual recall For women aged 50-74 - biennial recall 75 Yukon Begin at age 50 (age 40-49 accepted by self referral but not actively recruited) For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall 75+ British Columbia Begin at age 50 (age 40-49 accepted by self referral but not actively recruited) For women aged 40-49 - biennial recall For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall For higher than average risk women aged 40-74 – annual recall Alberta Begin at age 50 (age 40-49 accepted with physician referral for the first screen) For women aged 40-49 - annual recall For women aged 50-74 - biennial recall** Saskatchewan Begin at age 50 (age 49 accepted on the mobile if turning 50 in same calendar year) For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall (only if previously enrolled in the program) Manitoba Begin at 50 (ages 40-49 accepted to mobile unit only with physician referral) For women aged 40-49 - biennial recall For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall 74 (age 75+ accepted by self referral but not actively recruited or recalled) For high risk women aged 30-49 - annual recall For high risk women aged 50-69 – annual recall For women aged 50-69 - biennial recall** For women aged 70-74 - biennial recall** 74 (75+ only with a primary care provider referral) Northwest Territories Ontario Begin at age 50 (ages 30-49 accepted if high risk and referred by physician) *No screening program available in Nunavut but guidelines are under review **Women who meet specific criteria that may put them at increased risk for breast cancer will be recalled annually 74 (age 75+ accepted by self referral but not actively recruited or recalled) 75+ ** (Since September 2013) 75+ Breast Cancer Screening Programs: Provincial and Territorial Clinical Practice Guidelines, cont’d For asymptomatic women at average risk: Start Age Québec New Brunswick Begin at age 50 (accept ages 35-49 only with physician referral, at a program designated screening or referral center) Interval For women aged 50-69 - biennial recall Stop Age 69 (age 70+ only with a physician referral, at a program designated screening or referral center) Begin at age 50 (age 40-49 accepted only with physician or nurse practitioner referral) For women aged 50-74- biennial recall 74 (age 74+ only with a physician or nurse practitioner referral) (Since June 1, 2013) Nova Scotia Begin at age 40 For women aged 40-49 - annual recall For women aged 50-69 - biennial recall 70+ Prince Edward Island Begin at age 40 For women aged 40-49 - annual recall For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall 74 Begin at age 50 (age 40-49 accepted only with physician referral) For women aged 50-74 - biennial recall Newfoundland & Labrador 74 (age 74+ only if previously enrolled in the program) Distribution of mammography and CBE among breast screening programs Province/Territory (Program Distribution) Yukon Territory (1990) British Columbia (1988) Mammography alone Northwest Territories (2003) Clinical Breast Examination & Mammography No Organized Program Nunavut Newfoundland & Labrador (1996) Alberta (1990) Saskatchewan (1990) Manitoba (1995) Quebec (1998) Ontario (1990) Prince Edward Island (1998) New Brunswick (1995) Nova Scotia (1991) Breast Cancer Screening Programs in Canada Program Start Date Program Name Agency Responsible for Program Administration Nunavut* Northwest Territories 2003 2008 Breast Screening Program, Stanton Territorial Health Authority Breast Screening Program, Hay River Health and Social Services Authority Stanton Territorial Health Authority Hay River Health and Social Services Authority Yukon 1990 Yukon Mammography Program Government of Yukon (Yukon Hospital Corporation) British Columbia 1988 Screening Mammography Program of British Columbia BC Cancer Agency Alberta 1990 Alberta Breast Cancer Screening Program Alberta Health Services Saskatchewan 1990 Screening Program for Breast Cancer Saskatchewan Cancer Agency Manitoba 1995 BreastCheck CancerCare Manitoba Ontario 1990 Ontario Breast Screening Program Cancer Care Ontario Québec 1998 Programme québécois de dépistage du cancer du sein (PQDCS) Ministère de la Santé et des Services sociaux New Brunswick 1995 New Brunswick Breast Cancer Screening Services New Brunswick Cancer Network (NB Department of Health) Nova Scotia 1991 Nova Scotia Breast Screening Program Government of Nova Scotia Prince Edward Island 1998 PEI Breast Screening Program Government of Prince Edward Island Newfoundland and Labrador 1996 Breast Screening Program for Newfoundland and Labrador Eastern Health, Cancer Care Program *No screening program available in Nunavut but guidelines are under review Recall Following a Normal Mammogram Send out recall letters Coordination of recall for women following a normal screening episode performed by Any additional follow-up to first recall letter after no reply Age group for recall Nunavut* Northwest Territories Regional Coordination Centres Yukon Screening centre British Columbia Centralized management (Program or Agency) 40-74 (AHS Screen Test only) Centralized management (Program or Agency) 40-74 Saskatchewan Centralized management (Program or Agency) 50-74 Manitoba Centralized management (Program or Agency) 50-74 Ontario Centralized management (Program or Agency) 50-74** Québec Regional coordination centres 50-69 (not all regions) Screening centre 50-74 (postcard) Centralized management (Program or Agency) 40-69 Prince Edward Island Screening centre 40-74 Newfoundland and Labrador Screening centre 50-74 Alberta New Brunswick Nova Scotia *No screening program available in Nunavut **includes ages 30-49 if part of the high risk screening program 40-74 40-74 High Breast Density Recall and Recommendations Five provinces and territories recall women based on high breast density. Recommendations following a high breast density reading varies across the country. Automatic annual recall based on breast density Value considered high breast density Recommendation for high breast density levels > 75% Annual recall >75% Annual recall > 75% Annual recall Nova Scotia >75% Annual recall Newfoundland and Labrador >75% Annual recall Northwest Territories Saskatchewan Ontario July 2015 High Risk Screening: MRI Referral Guidelines Currently there are five provinces (British Columbia, Alberta, Ontario, Nova Scotia, Newfoundland and Labrador) that have developed standard guidelines for MRI referral. Table: The criteria or evidence that MRI referral is based upon per province Self-reported family history (>=2) of breast cancer (first degree relative) Selfreported family history of BRCA 1/2 Alberta ⱡ (>=3) Chest irradiation between the ages of 10 and 30 years Li-Fraumeni syndrome, Cowden syndrome, or Bannayan-RileyRuvalcaba syndrome ** *** **** ***** ⱡ **** Nova Scotia Newfoundland and Labrador Risk of breast cancer >20% (scored by validated assessment tools) * British Columbia Ontario Genetic testing BRCA 1 or 2 *British Columbia allows women with a 50% risk of BRCA mutation who have not yet received their BRCA testing ** British Columbia includes the following syndromes: Li Fraumeni Syndrome, Cowden’s Syndrome, HDGC (CDH-1), Peutz-Jegher’s Syndrome ***First degree relative, and have declined genetic testing themselves **** ≥25% using validated assessment tool ***** Chest irradiation before age 30 and at least 8 years prior to the screen ⱡ Upon confirmation of high risk status after genetic assessment e-cadherin mutation ⱡ High Risk Screening: MRI Referral Guidelines, cont’d Ontario has implemented an MRI screening component to its organized screening program for women considered at high risk for breast cancer. British Columbia, Nova Scotia and Alberta have established guidelines for the use of MRI among women considered to be at high risk (i.e. in British Columbia the women considered are confirmed cases of BRCA1 and BRCA2 mutation only). For more information on MRI guidelines for Nova Scotia please visit http://breastscreening.nshealth.ca/guidelines.pdf Newfoundland and Labrador is exploring the appropriateness of using MRI among women considered to be at high risk July 2015 Quality Assurance: Client Satisfaction Surveys Northwest Territories, British Columbia, Alberta, Manitoba, Nova Scotia and Newfoundland and Labrador evaluate client satisfaction on an ongoing basis. Table: Specific information collected when evaluating client satisfaction per province/territory Mammography exam Particular Screening Centre Organized Screening Program Northwest Territories (STHA site) British Columbia Alberta Manitoba Nova Scotia Newfoundland and Labrador July 2015 Quality Assurance: Evaluation of Radiologist Performance Most provinces and territories evaluate radiologists on their level of performance on an annual basis with the exceptions of Yukon and Prince Edward Island. New Brunswick collects this data but does not report on it. Table: Specific information collected when evaluating radiologist performance per province/territory Positive Predictive Value (PPV) Abnormal call rate Cancer detection rate Interval cancers Specific volume requirements for radiologists Northwest Territories (STHA site)ᶲ British Columbia Alberta Saskatchewan 1,000 / year Manitoba 1,000 / year** Ontario 1,000 / year*† Québec 480 / year 2,500 / year 480 / year*† 750/ year New Brunswick*** 1,200/ year* Nova Scotia Newfoundland and Labrador 2,000 / year 2,000 / year *Includes diagnostic and screening mammograms **All radiologists greatly exceed this number *** New Brunswick program policies stipulate that the RHAs must have a system for the annual review of mammography screening outcome data with Radiologists † This figure is currently under review and will likely be changed to align with CAR MAP requirements. ᶲ For Northwest Territories, the level of performance is done on the program as a whole (not specific radiologist) due to small volume numbers. Reference Slide Please use the following reference when citing information from this presentation: Cancerview.ca. Breast Cancer Screening Guidelines Across Canada: Environmental Scan. Toronto: Canadian Partnership Against Cancer; [enter date]. Available from: [enter URL link] July 2015