Cell Growth & Division Your Life Story 2 cells to ~75 trillion How much is a trillion? $100 dollars Largest bill in circulation $10,000 dollars Less than half an inch thick 100 $100 bills $1 million dollars 100 packets of $10,000 $100 million dollars 100 packets of $1 million $1 billion dollars 10 $100 million pallets $1 trillion dollars • There are only 7.2 billion people in the world • There are about 100 billion stars in the galaxy YOUR BODY = 75 trillion cells Each cell has the SAME copy of DNA in it How do we make sure those DNA copies are right? What if it goes wrong? Chromosomes Genetic information (DNA) is bundled into packages called chromosomes Chromatid: one copy of newly replicated chromosome Joined to the other chromatid by a centromere Why do cells replicate THEMSELVES? Cells go through mitosis for development, growth, and repair. The Cell Cycle 1. Interphase (preparing) (80% of time) Cell Cycle 1. Growth 2. DNA replication, twice as much Mitosis (division) Interphase DNA at the end of this phase (20% of time) 2. 3. Preparing for cell division Cell Division 1. Mitosis (cell division) 2. Cytokinesis (Division of cytoplasm) The Cell Cycle 4 Phases: G1, S, G2, M Interphase Cell Cycle G1 – Growth S – “Synthesis” – DNA replication, twice as much DNA at the end of this phase G2 – Preparing for cell division Cell Division M – 1. Mitosis (cell division) - 2. Cytokinesis (Division of cytoplasm) The Cell Cycle Warm Up Label this chromosome! 3.___________ 2.___________ 1.___________ 1. PROPHASE Chromosomes condense & coil. Nuclear membrane disintegrates. Spindle fibers form. 2. METAPHASE Chromosomes align in center by their centromeres Attach to spindle 3. ANAPHASE Chromatids separate. Chromatids pulled by the spindle fibers to opposite ends of the cell 4. TELOPHASE The cells divide into two. The chromosomes uncoil and the nucleus reforms. 5. CY TOKINESIS Cytoplasm pinches in half Each daughter cell has an identical set of duplicate chromosomes DNA Replication then Mitosis MITOSIS (Cell Division) STOP-MOTION MITOSIS Move objects very slowly and take several photos You can adjust the speed Make sure the phases are labelled with paper!