THE FUNCTIONS OF THE NERVOUS SYSTEM The Central Nervous System THE CENTRAL NERVOUS SYSTEM • The nervous system is divided into two subunits • Central nervous system (CNS) – Brain – spinal cord. • Peripheral nervous system – Any part of nervous system outside of CNS – Afferent and efferent. THE Cells of the CENTRAL NERVOUS SYSTEM • Contains neurons: obviously single neural cells. • Nucleus – A group of cell bodies (somas) in the CNS and a • Ganglion – Group of cell bodies in the peripheral nervous system. THE Cells of the CENTRAL NERVOUS SYSTEM • Contains neurons: obviously single neural cells. • Nerve : – is a bundle of axons running together – like a multi-wire cable. – Nerve is used only in the peripheral nervous system. • Tracts. – Bundles of neurons – Inside the CNS – Tracts = nerves Divisions of the CNS • Forebrain – Cerebral hemispheres • Frontal lobe • Parietal lobe • Occipital lobe • Temporal lobe – Thalamus and hypothalamus – Corpus callosum – Ventricles • Midbrain and Hindbrain – – – – Superior colliculi Thalamus Pineal gland Hindbrain • Pons; • Medulla; • Reticular activating system • Spinal Cord Let’s start at the top! The Forebrain! THE Forebrain • Forebrain – two cerebral hemispheres, – the thalamus, – the hypothalamus. • The large, wrinkled cerebral hemispheres dominate the brain’s appearance. • The longitudinal fissure – that runs the length of the brain – separates the two cerebral hemispheres, – Two cerebral hemispheres are mirror images of each other in appearance. • Remember: – Left hemisphere brain controls right side of body – Right brain hemisphere controls left side of body Gyri and sulci • The brain’s surface has many ridges and grooves that give it a very wrinkled appearance. • Several geographic landmarks: – gyrus. Each ridge – a sulcus The groove or space between two – Fissure: large sulcus Gyrus Sulcus convolutions of the cortex • The outer surface is the cortex, which is made up mostly of the cell bodies of neurons. – Because cell bodies are not myelinated, the cortex looks grayish in color, – Thus referred to as gray matter. • The cortex is only 1.5 – 4 mm thick, • Convolutions (folds) increase the amount of cortex by tripling the surface area. – Also provides axons easier access to cell bodies – Axons come together at central core of each gyrus – Here the brain appears white Organization of the CENTRAL NERVOUS SYSTEM • The central nervous system is arranged in a hierarchy. • As you ascend from the spinal cord through the hindbrain and midbrain to the forebrain, the neural structures become more complex and so do the behaviors they control. • The hemispheres are divided into four lobes – – – – – – frontal parietal, occipital temporal each named after the bone of the skull above it. Is size important? • Relation of brain size to body size versus intelligence – Brain size more related to body size – Brains of elephants and sperm whales 5-6x larger than human brain • What is important? – – – – Convolutions are the important variable! Greater number of gyri = more cortex Also; more gyri in cerebral hemispheres than lower brain parts More surface area = more connections THE frontal lobe • Frontal lobe – anterior to (in front of) the central sulcus – superior to (above) the lateral fissure. • Precentral gyrus, – extends the length of the central sulcus – Contains primary motor cortex, which controls voluntary (nonreflexive) movement. – The parts of the body are “mapped onto” the motor area of each hemisphere – Can be illustrated in the form of a homunculus, which means “little man.” • The secondary motor areas are located just anterior to the primary area. THE motor homunculus •More brain area is devoted to parts of body with greater/finer motor movement •Fingers •Hands •Lips •Legs •Arms •Little brain area devoted to motor movement of back, toes, etc. broca’s area • Broca’s area is located anterior to the motor area and along the lateral fissure. • Broca’s area controls speech production • contributes the movements involved in speech and grammatical structure. THE prefrontal cortex • Prefrontal Cortex – – – – – The most anterior part of the frontal lobes largest region in the human brain, Twice as large as in chimpanzees, Accounts for 29% of the total cortex. • The prefrontal cortex is involved in – – – – Planning and organization, Impulse control, Adjusting behavior in response to rewards and punishments, Some forms of decision making. THE prefrontal cortex Prefrontal Cortex THE prefrontal cortex • How know the effects of the Prefrontal cortex? – During the 1940s and 1950s surgeons performed tens of thousands of lobotomies, a surgical procedure that disconnected the prefrontal area from the rest of the brain. – Initially the surgeries were performed on very disordered schizophrenics, but many overly enthusiastic doctors lobotomized patients with much milder problems. • Effects? – The surgery calmed agitated patients, – Benefits came at a high price in that patients often became: • emotionally blunted • distractible • childlike in behavior. • Psychosurgery rarely used today to treat psychiatric problems THE parietal lobes • Parietal lobes – located superior to the lateral fissure – between the central sulcus and the occipital lobe. • Primary somatosensory cortex – located on the postcentral gyrus, – processes the skin senses (touch, warmth, cold, and pain), – Also senses that inform us about body position and movement. THE somatosensory homunculus • The somatosensory cortex also is organized as a homunculus, – size of each area depends on the sensitivity in that part of the body. THE parietal association areas • Association areas – Contained in each of the lobes – carry out further processing beyond what the primary area does – often combine information from other senses. • Parietal lobe association areas: – – – – receive input from the body senses and from vision. Help a person identify objects by touch help determine the location of the limbs Help locate objects in space. • Damage to the posterior parietal cortex may produce sensory neglect: a disorder in which the person ignores – – – – objects, people, activity on the side opposite the damage. Why the opposite side of the damage? THE temporal lobe • Temporal lobes • Separated from the frontal and parietal lobe by the lateral fissure • Three important areas: – Auditory projection area, – visual and auditory association areas – Additional language area: Wernicke’s Area. THE auditory or temporal cortex • Auditory cortex: – receives sound information from the ears – lies on the superior (uppermost) gyrus of the temporal lobe. • Wernicke’s area – Just posterior to the auditory cortex – interprets language input arriving from the nearby auditory and visual areas. – also generates spoken language through Broca’s area and written language by the way of the motor cortex. • Inferior temporal cortex – lower part of the lobe (as the name implies) – plays a major role in the visual identification of objects. THE occipital cortex • Occipital lobes – location of the visual cortex, – visual information is processed. • contains a map of visual space because adjacent receptors in the back of the eye send neurons to adjacent cells in the visual cortex.