1) What are the primary stages of wound healing in order of their occurrence?
A.
B.
C.
D.
Inflammatory, Remodeling, Proliferative
Inflammatory, Hemostatic, Proliferative, Chemotactic
Proliferative, Chemotactic, Remodeling
Inflammatory, Proliferative, Remodeling
2) Which statement best describes the Inflammatory stage?
A. It begins at the moment of injury and lasts for 2-4 days
B. It starts at the moment of injury and can last for up to 2 years
C. It starts within a week of injury and lasts 2 weeks
D. It begins when cytokines are released and ends when macrophages populate the
wound
3) What are the 2 key processes that occur during the inflammatory stage?
A.
B.
C.
D.
Collagen remodeling and wound contraction
Hemostasis and Chemotaxis
Fibroblast proliferation and wound epithelialization
All of the above
4) Which cells/cellular components are the most important during the
Inflammatory stage?
A.
B.
C.
D.
Fibroblasts, Myofibroblasts, and eosinophils
Epithelial cells, melanocytes, and platelets
Macrophages, neutrophils, and platelets
None of the above
5) Which cell is primarily responsible for stimulating fibroblast proliferation?
A.
B.
C.
D.
Macrophages
Neutrophils
Erythrocytes
Epithelial cells
6) Which stage of wound healing begins 4-5 days post-injury and lasts 2-3 weeks?
A.
B.
C.
D.
No stage of wound healing follows this timeline
Inflammatory stage
Proliferative stage
Remodeling stage
7) What is the dominant cell type of the Proliferative stage?
A.
B.
C.
D.
Neutrophils
Macrophages
Fibroblasts
Myofibroblasts
8) What is the predominant type collagen produced in the 2nd stage of wound
healing?
A.
B.
C.
D.
Type I
Type II
Type III
Type IV
9) At which week has the wound likely recovered 50% of pre-wound strength?
A.
B.
C.
D.
Week 4 post-injury
Week 6 post-injury
The wound never recovers 50% of its pre-wound strength
Week 8 post-injury
10) After sustaining a wound, what is the maximum proportion of pre-wound
strength that healing can recover?
A.
B.
C.
D.
100%
120%
50%
80%
11) What are the 3 main processes that occur during the Proliferative phase?
A.
B.
C.
D.
Collagen synthesis, Angiogenesis, and Epithialization
phagocytosis, apoptosis, and pinocytosis
imbibition and inosculation
Angiogenesis, hemostasis, chemotaxis, and collagen synthesis
12) What processes are directly involved in wound maturation?
A.
B.
C.
D.
Contracture, imbibition, and chemotaxis
Wound contraction, scarring, and scar remodeling
contraction and contracture
phagocytosis, contraction of wound, and chemotaxis
13) What happens in the 3rd stage of wound healing to increase the strength of the
wound?
1.
2.
3.
4.
Type I collagen is replaced by type III collagen
Type III collagen is replaced by type I collagen
Collagen is cross-linked
Collagen is remodeled and organized
A.
B.
C.
D.
E.
1, 3, and 4
2, 3, and 4
3 and 4 only
1 and 4 only
2 and 3 only
14) Why does a wound lose its purple-pinkish colour throughout the 3rd stage of
wound healing?
A.
B.
C.
D.
Collagen composition of the wound changes
Macrophages and neutrophils remove necrotic debris from the wound
Density of capillaries and fibroblasts declines
All of the above
15)
A.
B.
C.
D.
carry out the task of wound contraction at a rate of
/day
Myofibroblasts, < 0.75 mm
Myofibroblasts, > 0.75 mm
Macrophages, < 0.75 mm
Macrophages, < 0.75 cm
16) What is the difference between scar contraction, and scar contracture?
A. There is no difference, they refer to the same aspect of wound healing
B. Contraction is pathological, whereas contracture is physiological
C. Contraction is physiological, whereas contracture is pathological
D. Wound contraction refers to abnormal scar shortening, whereas wound
contracture refers to abnormal scar thickening
17) When should tetanus prophylaxis be administered?
A.
B.
C.
D.
Whenever a questionable vaccination history is encountered
When a patient has not had a booster in the last 10 years
If a patient has never been vaccinated for tetanus
All of the above
18) What are the pillars of wound preparation?
A. Hemostasis, and debridement
B. Irrigation and debridement
C. Irrigation, Hemostasis, and Debridement
D. Irrigation, Hemostasis, Debridement, and Primary intention closure
19) Which of the following statements are false?
A. Soaps and alcohols can damage wounded tissue further and should be avoided
B. Irrigation is important because it reduces bacterial load, and removes foreign
bodies from the wound
C. Debridement is optional depending on the status of the patient
D. Hemostasis can be achieved in a variety of ways, including applying pressure,
wound elevation, electrocautery, and ligation
20) What bacterial load precludes prompt closure by primary intention?
A. 10,000 microorganisms/g tissue
B. 100,000 microorganisms/g tissue
C. 1,000 microorganisms/g tissue
D. Primary intention closure can be implemented regardless of a wound’s bacterial
load