Post Resuscitation Care Learning outcomes To understand: • The need for continued resuscitation after return of spontaneous circulation • How to treat the post cardiac arrest syndrome • How to transfer the patient safely • The role and limitations of assessing prognosis after cardiac arrest Chain of Survival Post resuscitation care The goal is to restore: • Normal cerebral function • Stable cardiac rhythm • Adequate organ perfusion • Quality of life Post cardiac arrest syndrome • Post cardiac arrest brain injury: • Coma, seizures, myoclonus • Post cardiac arrest myocardial dysfunction • Systemic ischaemia-reperfusion response • ‘Sepsis-like’ syndrome • Persistence of precipitating pathology Airway and breathing • Ensure a clear airway, adequate oxygenation and ventilation • Consider tracheal intubation, sedation and controlled ventilation • Pulse oximetry: • Aim for SpO2 94 – 98% • Capnography: • Aim for normocapnia • Avoid hyperventilation Airway and breathing • Look, listen and feel • Consider: • • • • • • Simple/tension pneumothorax Collapse/consolidation Bronchial intubation Pulmonary oedema Aspiration Fractured ribs/flail segment Airway and breathing • Insert gastric tube to decompress stomach and improve lung compliance • Secure airway for transfer • Consider immediate extubation if patient breathing and conscious level improves quickly after ROSC Circulation • Pulse and blood pressure • Peripheral perfusion e.g. capillary refill time • Right ventricular failure • Distended neck veins • Left ventricular failure • Pulmonary oedema • ECG monitor and 12-lead ECG Disability Neurological assessment: • Glasgow Coma Scale score • Pupils • Limb tone and movement • Posture Glasgow Coma Scale score Glasgow Coma Scale score (GCS 3 – 15) Eyes (4) Verbal (5) 6 Motor (6) Obeys commands 5 Orientated Localises 4 Spontaneously Confused Normal flexion 3 To speech Inappropriate words Abnormal flexion 2 To pain Incomprehensible sounds Extension 1 Nil Nil Nil Further assessment History • Health before the cardiac arrest • Time delay before resuscitation • Duration of resuscitation • Cause of the cardiac arrest • Family history Further assessment Monitoring • • • • • • • Vital signs ECG Pulse oximetry Blood pressure e.g. arterial line Capnography Urine output Temperature Further assessment Investigations • • • • • • • Arterial blood gases Full blood count Biochemistry including blood glucose Troponin Repeat 12-lead ECG Chest X-ray Echocardiography Chest X-ray Transfer of the patient • • • • • • • • Discuss with admitting team Cannulae, drains, tubes secured Suction Oxygen supply Monitoring Documentation Reassess before leaving Talk to family Out-of-hospital VF arrest associated with Enteral nutrition AMI Insulin Cooling Inotropes Defibrillator Ventilation Pacing IABP Optimising organ function Heart • Post cardiac arrest syndrome • Ischaemia-reperfusion injury: • Reversible myocardial dysfunction for 2-3 days • Arrhythmias Optimising organ function Heart • Poor myocardial function despite optimal filling: • Echocardiography • Cardiac output monitoring • Inotropes and/or balloon pump • Mean blood pressure to achieve: • Urine output of 1 ml kg-1 hr-1 • Normalising lactate concentration Optimising organ function Brain • Impaired cerebral autoregulation – maintain • • • • • • ‘normal’ blood pressure Sedation Control seizures Glucose (4-10 mmol l-1) Normocapnia Avoid/treat hyperthermia Consider therapeutic hypothermia Therapeutic hypothermia Who to cool? • Unconscious adults with ROSC after VF arrest should be cooled to 32-34oC • May benefit patients after non-shockable/in-hospital cardiac arrest • Exclusions: severe sepsis, pre-existing medical coagulopathy • Start as soon as possible and continue for 24 h • Rewarm slowly 0.25oC h-1 Therapeutic hypothermia How to cool? • Induction - 30 ml kg-1 4oC IV fluid and/or external cooling • Maintenance - external cooling: • Ice packs, wet towels • Cooling blankets or pads • Water circulating gel-coated pads • Maintenance - internal cooling • Intravascular heat exchanger • Cardiopulmonary bypass Therapeutic hypothermia Physiological effects and complications • Shivering: sedate +/- neuromuscular blocking • • • • • • drug Bradycardia and cardiovascular instability Infection Hyperglycaemia Electrolyte abnormalities Increased amylase values Reduced clearance of drugs Assessment of prognosis • No clinical neurological signs can predict outcome < 24 h after ROSC • Poor outcome predicted at 3 days by: • Absent pupil light and corneal reflexes • Absent or extensor motor response to pain • But limited data on reliability of these criteria after therapeutic hypothermia Organ donation • Non-surviving post cardiac arrest patient may be a suitable donor: • Heart-beating donor (brainstem death) • Non-heart-beating donor Any questions? Summary • Post cardiac arrest syndrome is complex • Quality of post resuscitation care influences final outcome • Appropriate monitoring, safe transfer and continued organ support • Assessment of prognosis is difficult Advanced Life Support Course Slide set All rights reserved ©Australian Resuscitation Council and Resuscitation Council (UK) 2010