Applications of Data Mining – Dr. K. Sekar
IISc
K. SEKAR, Ph.D.
BIOINFORMATICS CENTRE
SUPERCOMPUTER EDUCATION AND RESEARCH
INDIAN INSTITUTE OF SCIENCE
BANGALORE 560 012
INDIA
sekar@physics.iisc.ernet.in
Voice: (91)-80-2932469 FAX : (91)-80-3600683
(91)-80-3601409
(91)-80-3600551
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
APPLICATIONS
OF
DATA MINING
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Abstract
Bioinformatics is one of the fastest
growing interdisciplinary areas in the
biological sciences and has explored in
such a way that we need powerful tools
to organize and analyze the data. An
overview will be presented on the general
features of data mining tools, techniques
and its applications.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics is the fashionable new
name for the field previously called
computational biology.The name is
preferred by many because it puts
the emphasis on the data storage
and analysis, rather than on the
biology, and the field is really data
driven.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
The term Bioinformatics is used to encompass almost all
computer applications in biological sciences, but was
originally coined in the mid 1980’s for the analysis of
biological sequence data.
The quantity of known sequences data outweighs protein
structural data and by virtue of the genome projects,
sequence database are doubling in size every year.
A key challenge of bioinformatics is to analyze the wealth of
sequence data in order to understand the amassed information
in term of protein structure function and evolution.
Wherever possible, a range of different methods should be
used, and the results should be married with all available
biological information.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Refers to database-like activities involving
persistent sets of data that are maintained in a
consistent state over essentially indefinite
periods of time.
Encompass the use of algorithmic tools to
facilitate biological database analyses.
Comprises the entire collection of information
management systems, analysis tools and
communication networks supporting biology.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
DATA MINING
Datamining
is
defined
as
“exploration and analysis by
automatic and semi-automatic
means, of large quantities of data
in order to discover meaningful
patterns and rules”.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
The central challenge is to derive
maximum results from the wealth
of data.This can be achieved by
establishing
and
maintaining
databases and providing search
and analysis tools to interpret the
data.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
DATABASE
IISc
Database is nothing but a collection of
quantitative
data
resulting
from
experimental
measurements
or
observations in various fields of
science.Recently interest in database
has been kindled through international
efforts to organize and analyze the data
and update the knowledge
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
A database is essentially just a store
of information.They are usually in the
form of simple files (just a flat file,
say).You can shove information into
this store or retrieve it from the store.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Derived Database
One of the greatest challenges in database
research is analyze the database in depth and
create derived databases to meet the needs
or demands without compromising the
sustainability and quality of the existing
database. Creating desired database is
expected is expected to dramatically reduce
the workload of the user community and will
serve as a highly focused database.
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Packages developed at the
Bioinformatics Centre
Raman Building
Indian Institute of Science
Bangalore 560 012
Principal Investigator
Dr. K. Sekar
E-mail sekar@physics.iisc.ernet.in
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Search Engines
144.16.71.10 / psst
144.16.71.2/bsdd
144.16.71.10/msgs
144.16.71.2/ssep
Protein Sequence Search Tool
Biomolecules Segment Display Device
Motif Search in Genome Sequence
Secondary Structural Elements in Protein
Programmers
1.
2.
3.
4.
5.
6.
7.
S.Saravanan
A.Ajmal Khan
C.K.Rajesh
T.Kamaraj
P.Selvarani
V.Shanthi
S.Sirajuddin Sheik
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
Database with Search facility
144.16.71.2/lsdb
144.16.71.2/lysdb
144.16.71.2/asdb
144.16.71.2/gsdb
IISc
Lipase Structural Database
Lysozyme Structural Database
3D-Amylase Database
Globin Structural Database
Programmers
1.
2.
3.
4.
5.
6.
7.
C.K.Rajesh
T.Kamaraj
P.Sundrarajan
P.Selvarani
V.Shanthi
A.S.Zahir Hussain
S.Sirajuddin Sheik
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
Software for
Structure analysis & manipulation
144.16.71.146/cap
144.16.71.146/rp
144.16.71.146/wap
144.16.71.146/sem
144.16.71.146/pdbgoodies
144.16.71.10/gpsm
144.16.71.146/mbd
144.16.71.146/dtf
Programmers
1.
2.
3.
4.
5.
6.
IISc
Conformation Angles Package
Ramachandran Plot
Water Analysis Package
Symmetry Equivalent Molecules Generator
PDBGOODIES
Geometrical Parameters for Small
Molecules
Measurability of Biovoet difference
Distribution of Temperature Factor
C.K.Rajesh
T.Kamaraj
P.Sundarajan
P.Selvarani
V.Shanthi
S.Sirajuddin Sheik
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Present Programmers
S.S. Sheik
S. Das
V.G. Vijay
J.J. Lakshmi
Ch. K. Kumar
C.C. Lingam
K.S. Mohan
S.A. Fernando
S.K. Raja
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
Protein Sequence Search Tool (PSST 1.1)
IISc
S.Saravanan,A.Ajmul Khan & K.Sekar
CURR.SCIENCE, (2000) 550 – 552
PDB Goodies – A Web based GUI to manipulate
Protein Data Bank files
A.S.Z.Hussain,V.Shanthi,S.S.Sheik,J.Jeyakanthan,P.Selvarani &K.Sekar
ACTA CRYST. (2002), D58, 1385 – 1386
Ramachandran Plot (RP)
S.Sheik,P. Sundararajan,A.S.Z Hussain & K.Sekar
BIOINFORMATICS (2002) 18, 1548-1549
Water Analysis Package (WAP)
V.Shanthi, C.K.Rajesh,J.Jayalakshmi,V.G.Vijay & K.Sekar
J.APPL.CRYST. (2003) 36, 167-168
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
CADB: Conformation Angles Data Base of proteins
IISc
S.S. Sheik, P. Ananthalakshmi, G. Ramya Bhargavi & K. Sekar
NUCL. ACIDS RES., (2003) 448-451
SSEP: Secondary Structural Elements of Proteins
V. Shanthi, P. Selvarani, Ch. K. Kumar, C.S. Mohire & K. Sekar
NUCL. ACIDS RES., (2003) (In the press)
SEM: Symmetry Equivalent Molecules – A web based
GUI to generate and visualize the macromolecules
A.S.Z. Hussain, V. Shanthi, Ch. K. Kumar, C.K. Rajesh, S.S. Sheik & K. Sekar
NUCL. ACIDS RES., (2003) (In the press)
Biomolecules Segment Display Device (BSDD)
P.Selvarani,V.Shanthi,C.K.Rajesh,S.Saravanan & K.Sekar
J.MOL. GRAPHICS & MODELLING (2003) (in press)
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Department of Biotechnology
Ministry of Science & Technology
Govt. of India, India
&
Jai Vigyan National Science Foundation
Govt. of India, India
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Professor M. Vijayan
Professor N. Balakrishnan
Professor S.M. Rao
Professor S. Ramakumar
Colleagues and Friends
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
President of Nagoya University
Professor Takashi Yamane
&
Other members
Biotechnology & Biomaterial Science
Bioinformatics Centre & Supercomputer Education and Research Centre
Applications of Data Mining – Dr. K. Sekar
IISc
Bioinformatics Centre & Supercomputer Education and Research Centre