Elizabeth Hanus NTR 402 Prof. FitzPatrick 10/24/14 Avocado Consumption in the Diet and Impact of Phytosterols I. INTRODUCTION: The purpose of this paper is to examine the potential beneficial effects of avocado consumption and phytosterols in the diet. Avocados can be a valuable addition to a wellbalanced diet because they contain healthy fats such as monounsaturated and polyunsaturated fatty acids. In comparison, saturated or trans fatty acids could have negative effects on blood cholesterol levels when consumed in excess. They also contain compounds called phytosterols, which are cholesterol-like substances found naturally in certain foods that have been shown to lower blood cholesterol levels by blocking intestinal cholesterol absorption and reducing hepatic cholesterol synthesis (Duester, 2001). In addition, these compounds are suggested to have a beneficial effect on heart health, weight loss, and risk of coronary heart disease (Dreher & Davenport, 2013). Avocados are the fruit that contains the highest amount of phytosterols per serving at 57mg per 68g or one-half of an avocado. It was previously believed that oranges were the fruit highest in phytosterols, but when compared with avocados ounce per ounce, avocados ranked four times higher in phytosterol content, specifically beta-sitosterol (Duester, 2001). Official serving size is one-fifth of an avocado (30g), but the National Health and Nutrition Examination Survey (NHANES) reports that a more common serving size typically consumed is one-half of an avocado (Dreher & Davenport, 2013). II. ACTIVE COMPONENTS The active components in the avocado that make them beneficial to health, as previously mentioned, are comprised of monounsaturated fatty acids, polyunsaturated fatty acids, and phytosterols. The standard serving of avocado (one fifth or 30g) consists of 4.5g of total fat, of which 3g are monounsaturated, 0.5g are polyunsaturated, and 0.5g are saturated. The main three types of phytosterols in an avocado consist primarily of betasitosterol at 74.6mg per 100g of edible avocado, campesterol at 5.1g per 100g, and the lowest stigmasterol at <3g per 100g (Duester, 2001). The structure of phytosterols is similar to that of cholesterol in animals in that it stabilizes the cell membrane in plants, providing structure to the phospholipid bilayers (Moreau, 2002). Phytosterols can also be found included in commercial dietary supplements, but a similar amount of 132mg can be found in the average California avocado weighing 173g (Duester, 2001). III. PROCESSING It is worth noting that different varieties of avocados contain different nutrient profiles, especially in relation to fat content. There are hundreds of varieties of avocados available throughout the world, but the most popular varieties seen throughout grocery stores in the United States are grown in California and Florida. The botanical name for avocados is Persia Americana, and they are a member of the Lauraceae family, which includes the plants that produce edible substances such as cinnamon, camphor, sassafras and bay leaf (USDA, 2014). The avocado is distinguished by it’s oval shape, large inner pit and surrounding light green, creamy flesh. Hass avocados, which are grown in the state of California, are a variety known for their dark, purplish black, bumpy skin and light green flesh. They are most often desired for their higher fat content and use in dips and spreads such as guacamole. Other varieties grown in California include Bacon, Fuerte, Gwen, Lamb Hass, Pinkerton, Reed, and Zutano (California Avocado Commission, 2014). The other most common variety of avocado is grown in the state of Florida, sometimes labeled as “lite” avocados due to their slightly lower fat and calorie content. This variety has a smooth, green skin when ripe, and is desired in dishes where the slices of avocado would need to hold their shape (Collins, 2013). There are over 50 varieties of Florida avocados, but the most successful commercial varieties include Doni, Lula, Bernecker, and Pollock (Specialty Produce, 2014). IV. HUMAN STUDIES It has been proposed through various research studies that compounds in the avocado, primarily different varieties of phytosterols, have had beneficial effects on blood lipid levels and cardiovascular health when consumed along with a healthful diet. Due to this research, the United States Cholesterol Education Adult Treatment Panel III has recommended that 2g of phytosterols per day should be added to the diet to reduce lowdensity lipoprotein (LDL) cholesterol levels and reduce the risk of coronary heart disease (Lin et al., 2009). Researchers such as Lin et al. have examined the effect of phytosterols in their glycosylated form on cholesterol absorption in humans in a randomized crossover study design. The study extracted phytosterol glycosides from soy lecithin, a bioactive form of free phytosterols that have been shown to reduce cholesterol, as opposed to nonsoluble crystalline forms that have not been shown to have the same effect. Subjects studied included 12 healthy individuals ranging from 18-80 years old with plasma LDL cholesterol <190mg/dL and triglyceride levels <250mg/dL. Subjects were either given a meal of phytosterol glycoside-enriched pudding, phytosterol ester-enriched pudding, or a placebo pudding without phytosterols. Cholesterol absorption tests were administered and plasma samples were taken before the start of the study and after the test meal was consumed to evaluate the potential effect of phytosterols on cholesterol absorption. The results concluded that phytosterol glycosides reduced cholesterol absorption by 37.6% and phytosterol esters reduced cholesterol absorption by 30.6%, similar to results of other studies pertaining to the subject matter. Thus, it is suggested that phytosterol glycosides and esters appear to have a beneficial effect on reducing the absorption of cholesterol into the human body. Research suggests that a diet high in fruit and vegetables shows a correlation with a decrease in body weight and lower body mass index (Fulgoni et al., 2013). While avocados are higher in fat and energy density than other fruits and vegetables, they have been shown to increase satiety and therefore it is likely the individual will eat less at mealtimes (Bes-Rastrollo et al., 2008). Despite popular belief that foods high in fat will lead to weight gain, several studies have shown that consuming healthy fats, such as those found in avocados, can lead to a more significant weight loss when consumed in moderation when compared to eating a low-fat diet (Bes-Rastrollo et al., 2008). This effect has also been seen in foods such as olive oil and tree nuts (Bes-Rastrollo et al., 2008), but a benefit of eating avocados instead of these particular foods for weight loss is that they provide a similar nutrient profile with less than half of the calories per ounce serving (USDA, 2011). Avocados can also be used in food preparation as an alternative to other high-calorie foods such as mayonnaise or other dressings on sandwiches or salads to reduce calorie content and increase nutritional value. It has also been proposed through numerous clinical trials that consumption of phytosterols can have a beneficial effect on cardiovascular health and reduced risk of coronary heart disease (Dreher & Davenport, 2013). The reasoning for this claim is such that by lowering LDL cholesterol and increasing HDL cholesterol to recommended levels, heart health improves. In addition to phytosterols, avocados contain other nutrients that are suggested to contribute to heart health, such as potassium, magnesium, antioxidant vitamins such as vitamin E and vitamin C, vitamin K, carotenoids, and phenolic compounds (Dreher & Davenport, 2013). V. CONCLUSION The cost of avocados in the United States typically ranges from 1 to 2 dollars per avocado (Hannaford Grocery, 2013), although the price may vary depending on abundance of the crops each year and proximity to the states highest in avocado production, such as California and Florida. When looking at the cost and value of phytosterol content, as previously mentioned, the amount of phytosterols in one avocado is comparable to that of a dietary phytosterol supplement (Duester, 2001). The cost of a dietary phytosterol supplement, such as Benecol, can range from approximately 4 dollars for the enriched margarine spread, which contains 0.5g of plant phytosterols per 1 tablespoon serving, or up to 27 dollars for a chewable tablet containing 0.8g of phytosterols per tablet (Hannaford Grocery, 2013). While the cost of buying a whole avocado can be slightly higher than other products based on phytosterol content per serving, the avocado has additional benefits not seen in other products such vitamin C and E, carotenoids, and the healthy fat profile of monounsaturated and polyunsaturated fatty acids. However, it would prove challenging to reach the 2g per day dose of phytosterols recommended to lower LDL cholesterol and reduce risk of coronary heart disease with avocados alone. In conclusion, based on the nutritionally dense profile of the avocado, including high quantity of monounsaturated fatty acids, polyunsaturated fatty acids, and cholesterol lowering properties of phytosterols and related impact on heart health and risk of cardiovascular disease, it is suggested that avocados are a heart-healthy and beneficial addition to a well balanced diet. In addition, avocados can have the potential to lower LDL cholesterol when consumed daily in the diet and in addition to other plant sterolcontaining products. References Avocado Nutrition Facts and Health Benefits | California Avocado. (n.d.). California Avocado. Retrieved September 2, 2014, from http://www.californiaavocado.com/nutrition Bes-Rastrollo, M., van Dam, R. M., Martinez-Gonzalez, M. A., Li, T. Y., Sampson, L. L., & Hu, F. B. (2008). Prospective study of dietary energy density and weight gain in women. The American Journal of Clinical Nutrition, 88(3), 769-777. Collins, K. (2013, September 11). Differences Between Types of Avocados | American Institute for Cancer Research (AICR). AICR All. Retrieved September 1, 2014, from http://www.aicr.org/press/health-features/healthtalk/2013/09sept2013/Differences-Between-Types-of-Avocados.html Dreher, M. L., & Davenport, A. J. (2013). Hass avocado composition and potential health effects. Critical Reviews in Food Science and Nutrition, 53(7), 738-750. Duester, K. C. (2001). Avocado fruit is a rich source of beta-sitosterol. Journal of the American Dietetic Association, 101(4), 404-405. Florida Avocados. (n.d.). Information, Recipes and Facts. Retrieved October 23, 2014, from http://www.specialtyproduce.com/produce/Florida_Avocados_365.php Food Group. (n.d.). Foods List. Retrieved October 23, 2014, from http://ndb.nal.usda.gov/ndb/ Fulgoni, V. L., Dreher, M., & Davenport, A. J. (2013). Avocado consumption is associated with better diet quality and nutrient intake, and lower metabolic syndrome risk in US adults: results from the National Health and Nutrition Examination Survey (NHANES) 2001‚Äì2008. Nutrition Journal, 12(1), 1. Lin, X., Ma, L., Racette, S. B., Spearie, C. L., & Ostlund, R. E. (2009). Phytosterol glycosides reduce cholesterol absorption in humans. AJP: Gastrointestinal and Liver Physiology, 296(4), G931-G935. Moreau, R. A., Whitaker, B. D., & Hicks, K. B. (2002). Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and healthpromoting uses. Progress in Lipid Research, 41(6), 457-500. Plants Profile for Persea americana (avocado). (n.d.). Plants Profile for Persea americana (avocado). Retrieved October 23, 2014, from http://plants.usda.gov/core/profile?symbol=PEAM3 Supermarket, Grocery, Coupons, Pharmacy & Recipes. (n.d.). Supermarket, Grocery, Coupons, Pharmacy & Recipes. Retrieved October 23, 2014, from http://www.hannaford.com/home.jsp