Naturopathic Medicine Renaissance Holistic Health Philosophy of Naturopathic Medicine Naturopathic Medicine is a distinctively natural approach to health and healing that recognizes the integrity of the whole person. Naturopathic Medicine is heir to the vitalistic tradition of medicine in the Western world, emphasizing the treatment of disease through the stimulation, enhancement, and support of the inherent healing capacity of the person. The practice of Naturopathic Medicine emerges from six underlying principles of healing. These principles are based on the objective observation of the nature of health and disease, and are continually reexamined in light of scientific analysis. It is these principles that distinguish the profession from other medical approaches. 1. The healing power of nature. vis medicatrix naturae The body has the inherent ability to establish, maintain, and restore health. The physician's role is to facilitate and augment this process, to act to identify and remove obstacles to health and recovery, and to support the creation of a healthy internal and external environment. 2. Identify and treat the cause. tolle causam Illness does not occur without cause. Underlying causes of disease must be discovered and removed or treated before a person can recover completely from illness. Symptoms are expressions of the body's attempt to heal, but are not the cause of disease. Symptoms, therefore, should not be suppressed by treatment. Causes may occur on many levels including physical, mental, emotional, and spiritual. The physician must evaluate fundamental underlying causes on all levels, directing treatment at root causes rather than at symptomatic expression. 3. First do no harm. primum no nocere Illness is a purposeful process of the organism. Therapeutic actions should be complimentary to and synergistic with this healing process. The physician's actions can support or antagonize the actions of the vis medicatrix naturae. Therefore, methods designed to suppress symptoms without removing underlying causes are considered harmful and are avoided or minimized. 4. Treat the whole person. The multifactorial nature of health and disease Health and disease are conditions of the whole organism, a whole involving a complex interaction of physical, spiritual, mental, emotional, genetic, environmental, social, and other factors. The physician must treat the whole person by taking all of these factors into account. The harmonious functioning of all aspects of the individual is essential to recovery from and prevention of disease, and requires a personalized and comprehensive approach to diagnosis and treatment. 5. The physician as teacher. docere Beyond an accurate diagnosis and appropriate prescription, the physician must work to create a healthy, sensitive interpersonal relationship with the patient. The physician's major role is to educate and encourage the patient to take responsibility for health. The physician is a catalyst for healthful change, empowering and motivating the patient to assume responsibility. It is the patient, not the doctor, who ultimately creates/accomplishes healing. The physician must also make a commitment to his/her personal and spiritual development in order to be a good teacher. 6. Prevention. Prevention is the best "cure" The ultimate goal of any health care system should be prevention. This is accomplished through education and promotion of lifehabits that create good health. The physician assesses risk factors and hereditary susceptibility to disease and makes appropriate interventions to avoid further harm and risk to the patient. The emphasis is on building health rather than on fighting disease. Naturopathic Education Naturopathic medical colleges are four-year postgraduate schools with admission requirements comparable to those of conventional medical schools. Fourth year students must complete 12 months of clinic internship where they treat patients under the supervision of licensed Naturopathic Doctors. Naturopathic Education Naturopathic education may be completed at one of six four-year postgraduate schools in North America that are part of the A.A.N.M.C. (Association of Accredited Naturopathic Medical Colleges) including: •Canadian College of Naturopathic Medicine in Toronto •Boucher Institute of Naturopathic Medicine in British Columbia •National College of Naturopathic Medicine in Oregon •Bastyr University in Washington •Southwest College of Naturopathic Medicine in Arizona •The University of Bridgeport, College of Naturopathic Medicine in Connecticut Naturopathic Education The degree of Doctor of Naturopathic Medicine requires four years of graduate level study in the medical sciences including: • anatomy • physiology • biochemistry • pathology • microbiology • immunology • pharmacology • laboratory diagnosis • clinical and physical diagnosis • cardiology • neurology • radiology • minor surgery • obstetrics • gynecology • pediatrics • dermatology • other clinical sciences Naturopathic Regulation Professional Licensing / Regulatory Boards Canadian Association of Naturopathic Doctors (CAND) www.cand.ca The College of Naturopathic Physicians of British Columbia (CNPBC) www.cnpbc.bc.ca Ontario Board of Directors of Drugless Therapy - Naturopathy (BDDT-N) www.BoardofNaturopathicMedicine.on.ca Manitoba Naturopathic Association www.mbnd.ca Saskatchewan Association of Naturopathic Practitioners www.sanp.com Alberta Association of Naturopathic Practitioners www.naturopathic-alberta.com Provincial Naturopathic Associations British Columbia Naturopathic Association (BCNA) www.bcna.ca Alberta Association of Naturopathic Practitioners (AANP) www.naturopathic-alberta.com Saskatchewan Association of Naturopathic Practitioners (SANP) www.sanp.ca Manitoba Naturopathic Association (MNA) www.mbnd.ca Ontario Association of Naturopathic Doctors (OAND) www.oand.org Quebec Association of Naturopathic Medicine (QANM) www.qanm.org New Brunswick Association of Naturopathic Doctors (NBAND) www.nband.ca Newfoundland and Labrador Association of Naturopathic Doctors (NLAND) Nova Scotia Association of Naturopathic Doctors (NSAND) www.nsand.ca Prince Edward Island Association of Naturopathic Doctors (PEIAND) United States Affiliate: American Association of Naturopathic Physicians (AANP) www.naturopathic.org Naturopathic Accreditation and Examinations Council on Naturopathic Medical Education (CNME) www.cnme.org North American Board of Naturopathic Examiners (NABNE) www.nabne.org Naturopathic Physicians Licensing Examination Board (NPLEX) www.nabne.org Naturopathic Regulation Change in regulation from DPA (Drugless Practitioners Act) to the RHPA (Regulated Health Practitioners Act) May 28, 2007 Naturopathy Act is passed as part of Bill 171, Health Systems Improvements Act to ensure regulation under the RHPA Other professions regulated by the RHPA: College of Midwives College of Dental Technologists College of Pharmacists College of Chiropractors College of Respiratory Therapists College of Dental Surgeons College of Optometrists College of Dieticians College of Occupational Therapists College of Physicians and Surgeons College of Psychologists College of Chiropodists College of Massage Therapists Research Peer-reviewed Medical Journals Journal of Integrative Medicine Integrative Medicine: A Clinicians Journal (IMCJ) The Journal of Alternative and Complementary Therapies The Journal of Alternative Therapies in Health and Medicine International Journal of Naturopathic Medicine American Journal of Clinical Nutrition Journal of Orthomolecular Medicine The Alternative Medicine Review Journal of Environmental Medicine Applied Nutritional Science Reports (ANSR) Naturopathic Modalities Clinical Nutrition That food is the best medicine is a cornerstone of naturopathic practice. Many medical conditions can be treated more effectively with foods and nutritional supplements than they can by other means, with fewer complications and side effects. Naturopathic physicians use dietetics, natural hygiene, detoxification, and nutritional supplementation in practice. Naturopathic Modalities Botanical Medicine Many plant substances are powerful medicines. Where single chemicallyderived drugs may only address a single problem, botanical medicines are able to address a variety of problems simultaneously. Their organic nature makes botanicals compatible with the body's own chemistry; hence, they can be gently effective with few toxic side effects. Naturopathic Modalities Homeopathic Medicine Homeopathic medicine is based on the principle of "like cures like." It works on a subtle yet powerful energetic level, gently acting to strengthen the healing capacity of the body. Naturopathic Modalities Traditional Chinese Medicine Oriental medicine is a complimentary healing philosophy to naturopathic medicine. Meridian theory offers an important understanding of the unity of the body and mind, and adds to the Western understanding of physiology. Acupuncture provides a method of treatment which can unify and harmonize the imbalances present in disease conditions, which, if untreated, can result in illness. Naturopathic Modalities Traditional Chinese Medicine Element: Fire Organ: Heart Function: Houses the mind (emotions) Emotion: Grief Analogy: Give someone your heart Example: Adam Sandler in Reign Over Me Western Diagnosis: Bipolar Disorder TCM Diagnosis: Fire Harassing the Heart Naturopathic Modalities Psychological Medicine Mental attitudes and emotional states may influence, or even cause, physical illness. Counseling, nutritional balancing, stress management, and other therapies are used to help patients heal on the psychological level. Naturopathic Medicine Intravenous Therapy IV therapy allows therapeutic doses of vitamins and minerals to be administered to an individual in an acute state of illness, or a chronically debilitated state so as to more rapidly bring upon healing. Intravenous therapy is an effective tool to use in chelating heavy metals, and as well may be used as adjunctive cancer therapy. Naturopathic Medicine and Autism Prevalence of Autism Autism now estimated to affect 1 in 166 children Frequency of autism estimated to have increased 3.8%/year from 1966-1997 Ratio of 3:1 boys:girls Causes of Autism Autism undoubtedly has a multifactorial causation profile. 1. Genetic 2. Environmental - Toxins Infections (vaccinations) Inflammation Oxidative stress Adverse reactions to foods Treatment Objectives To remove offending substances from the diet; introduce only hypoallergenic foods into the diet. To repair damage in the gastrointestinal system. To control the immune system. To eliminate any presence of yeast. To address possible heavy metal toxicity. To minimize oxidative stress and repair free radical damage. To introduce systemic (whole body) antiinflammatory agents. To address possible impact of vaccinations. Typical Naturopathic Treatment Plan Heavy Metal Toxicity Asses presence of heavy metals Investigate heavy metal exposure Undergo chelation therapy for removal of heavy metals Gastrointestinal Health Wheat (gluten) and milk (casein) free diet Candida diet (sugar, arabinose, tartaric acid) Hypoallergic diet to prevent autoimmunity Anti-inflammatory diet to control inflammation Supplements including EFA, probiotics, glutamine, MCT Brain Chemisty Evaluate levels of Glutamate/GABA, serotonin and dopamine Nutrition Why does food matter? Anecdotal evidence of over 30 years demonstrates high incidence of impaired GI tract function and food intolerance in autistic children. Goodwin et al, 1971 In a survey of 500 parents of autistic children, over 50% reported loos stools or frequent periods of diarrhea. Lightdale et al, 2001 In a survey of parents of 116 autistic children the following data was collected (see next slide): Horvath & Perman, 2002 Nutrition Intestinal Disorders Associated Autism Autistic child (% of 116 aged 3-10) Sibling (% of 43) Number of GI Symptoms 0 1 2 3 4 17 10 17 15 41 72 16 7 0 5 Specific Symptoms Abdominal Discomfort Gas (2-3 events/week) Bloating Belching Reflux 44 54 34 24 16 9 19 5 9 5 Frequency of Bowel Movements > 3/day 2-3/day 1-2/day 3-4/week 1-2/week 20 25 35 7 6 2 13 72 2 7 Stool Characteristics Loose/watery Soft Normal Changing Foul Smelling Sour Smelling Normal Smelling 32 18 13 23 49 8 43 2 21 81 0 0 7 93 Nutrition Why does food matter? The Intestine as a protective barrier Miller AL. “The pathogenesis, clinical implications and treatment of intestinal hyperpermeability.” Alternative Medicine Review, 1997; 2(5):365-376. Walker M. “The leaky gut syndrome.” Explore!, 1996;7(3):9-12. IgG Food Allergies and the symptoms of an overactive immune system Gaby AR. “The role of hidden food allergy/intolerance in health and disease.” Alternative Medicine Review, 1998;3(2):90-1000. Jacobson MB, Aukrust P, Kittang E, et al. “Relation between food provocation and systemic immune activation in patients with food intolerance.” The Lancet, 2000; 356:400-401. Rudat K-H. “Intestine-specific overstress diseases – concerning the functional utility of the intestinal tract and the immune system.” Explore!, 1996;7(3):24-28. Contribution to chronic inflammation and therefore further destruction Sutter, Frederick T. “Natural Therapies for Rheumatoid Arthritis and Other Chronic Inflammatory Conditions.” Applied Nutritional Science Reports, 2000;419. Lerman, Robert H. “A Case Study Evaluating the Effects of an Inflammatory-Modulating Medical Food and a Nutritional Supplement Containing a Proprietary Blend of RIAA, Vitamin D3, Selenium, and Zinc in a Patient with Crohn’s Disease.” Applied Nutritional Science Reports, 2005;1271. Nutrition Why does food matter? Opium, gluten and milk in Autism Breakdown of gluten and casein by secretions of the pancreas and the intestines create peptides (small proteins) that are similar in structure to endorphins (the body’s natural pain killer). These peptides have opiate-like qualities. Normally, these peptides are degraded and excreted with little effect. In autistic patients, these peptides can lead to reduced brain electrical activity and thus altered behavioural changes. This activity is improved by naltrexone administration (an opioid antagonist) therefore proving opioid action. Much anecdotal evidence exists of significant improvement in autistic symptoms when milk and wheat are eliminated from the diet. A study using 15 autistic children correlated significantly increased urine exorphin level with autistic spectrum patients. Elimination of milk and gluten from the diet resulted in improvement of social, cognitive and communications sills, commensurate with reduction of urinary exorphin level. Knivsberg et al, 1990 Nutrition WhyWhat does food matter? is the deal with yeast? Byproducts of yeast, including arabinose and tartaric acid, are frequently elevated in urine samples of people with autism. History of frequent ear infections, and therefore anti-biotic use, strongly correlates with presence of these byproducts – kill bacteria, more food for yeast to thrive on. Arabinose is found in greatest amounts in apples. Values may be significantly increased after drinking apple juice or eating apples/applesauce. Several parents have reported worsening of symptoms within a short time after their children ate apples. One child with a very high urine arabinose was examined by MRI and found to have diffuse demyelination. Without an intact myelin cover, the nerve impulses in the brain are “short-circuited.” Tartaric acid is most likely a product of the breakdown of arabinose. It is available as a food additive (from the wine making industry) in baking powder, grape and lime flavoured beverages, and poultry. It may also be found in grapes and grape products. Cream of tartar is nearly pure tartaric acid. Tartaric acid disallows the formation of malic acid which then interrupts the process of gluconeogenesis which then decreases the amount of glucose available to the brain leading to foggy thinking and decreased energy. Shaw, William PhD. Biological Treatments for Autism and PDD. Lenexa: The Great Plains Laboratory, 2002. Nutrition Autism and Brain Chemistry Balancing glutamate and GABA Glutamate is an excitatory neurotransmitter that plays a role in cellular memory and pain perception. When glutamate is imbalanced symptoms such as chronic pain, mood lability, and mania are existent and signs such as neurodegeneration become apparent. GABA is the primary inhibitory neurotransmitter of the brain and is of utmost importance for cell to cell contact. It can be thought of as enhancing communication by quieting the noise caused by excitatory neurotransmitters, as the case would be in a bar where it is difficult to communicate because of so much excitation and background noise, while in a quiet living room by the fire communication may be enhanced simply by listening. When GABA is out of range (high or low), it is likely that an excitatory neurotransmitter is firing too often in the brain. GABA is said to be the ‘radiator fluid’ for the brain in that it is meant to cool the heat caused by the metabolic function of the excitatory neurotransmitters. GABA receptors mediate anxiolytic, sedative, and anti-convulsant activity. When GABA is imbalanced symptoms such as anxiety, depression, restlessness, excessive worrying, sleep disturbances, and insomnia result. Magnesium, B6, Green Tea Extract, taurine and NAC balance glutamate and GABA activity Lombard, Jay. “The Neurobiology of Mood and Cognitive Disorders”. Lecture. Metagenics Educational Programs. Syracuse, New York. 7 October 2007 Nutrition Heavy Metal Toxicity Individual and cumulative amounts of mercury in vaccinations exceed safety guidelines Is a byproduct of industrial waste transformed by microorganisms in the environment, bioaccumulates in water organisms (largest amount in salmon and tuna) Toxic to all tissues and organs Important in those with candida as mercury inhibits an enzyme that produces an ion that is one of the key defense mechanisms against candida Treatment by chelation including garlic, cilantro, vitamin C, calcium, NAC, selenium, lipoic acid Shaw, William PhD. Biological Treatments for Autism and PDD. Lenexa: The Great Plains Laboratory, 2002. Supplements Essential Fatty Acids (EFA) Simoppulos AP. “Omega-3 fatty acids in inflammation and autoimmune diseases. “J Am Coll Nutr. (2002):495-505. Review. Probiotics (Saccharomyces boulardii, bifidobacteria, Lactobacillus reuteri and casei) Bongaerts GPA, Severijnen RSVM. “The beneficial, antimicrobrial effect of probiotics.” Medical Hypothesis, (2001):174177 Erickson KL, Hubbard NE: Probiotic immunomodulation in health and disease. Journal of Nutrition, (2000):403S-409S. Glutamine – fuel for cells of the colon; production of ATP used as energy by cells of colon Souba, Smith, and Wilmour. “ Glutamine metabolism by the intestinal tract.” JPEN (1985):608-17. Magnesium and Vitamin B6 – as cofactors bound to lysine sites that are blocked because of pentosidine formation on that site; promotes GABA formation Mousain-Bosc et al. “Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. II. Pervasive developmental disorder-autism.” Magnesium Research, (2006):53-62. Calcium – prevention against calcium deficiency from milk-free diet (Symptom – itchy eyes) Shaw, William PhD. Biological Treatments for Autism and PDD. Lenexa: The Great Plains Laboratory, 2002. MTC (Medium Chain Triglycerides) – contains mostly caprylic acid which is an antifungal Shaw, William PhD. Biological Treatments for Autism and PDD. Lenexa: The Great Plains Laboratory, 2002. Vitamin B12 – absorbed in the ileum where damage may be apparent (as study sited 93% autistic children had ileal lymph node hyperplasia and 8% of subjects had ileitis) Wakefield et al, 2002 Pharmaceutical Treatment Neuroleptics - Reduction of aggression and irritability Drugs: Haloperidol; (atypical – risperidone) Nutrient Depletions: Co Q-10, melatonin and vitamin E Serotonin Reuptake Inhibitors - Children having co-existing depression or with obsessive or ritualistic behaviours Drugs: Fluoxetine, Clomipramine, Sertaline, Paroxetine Nutrient Depletions: Sodium, folic acid and melatonin Opioid Receptor Antagonist - Children with self-injurious behaviours Drugs: Naltrexone Nutrient Depletions: unknown Anti-convulsant - Seizure Control Drugs: Valproic acid and carbamazepine Nutrient Depletions: Biotin, niacin, L-carnitine, folic acid, zinc, calcium and all fat soluble vitamins (A,D,E and K) Naturopathic Doctors are not legally permitted to provide information on pharmaceuticals regarding their continued use or changes in dosage. Naturopathic Doctors are however, knowledgeable about pharmaceuticals in terms of their mechanism of action, their interactions with other drugs or supplements, and nutritional depletions they may cause. Consider the care of a Naturopathic Doctor Lorraine Stuyt BSc., N.D. While we may not be able to control all that happens to us, we can control what happens inside us. Ben Franklin