EDEN
Integrated Project proposal
Florence Putterman
Emerging Diseases in a changing
European Environment
FP6 call
“The aim is to identify, evaluate and catalogue European
ecosystems and environmental conditions linked to global change,
which can influence the spatial and temporal distribution and
dynamics of pathogenic agents.
A co-ordinated European approach is needed to provide predictive
emergence and spread models including global and regional
prevention, early warning, surveillance, and monitoring tools and
scenarios.
Co-ordination with international organizations and third world
countries is essential.”
Keywords
The aim is to
identify,
evaluate and
catalogue
European
ecosystems and
environmental conditions
linked to global change and which can
influence
the spatial distribution
the temporal distribution and
the dynamics
of pathogenic agents.
Coordinated European
approach
Predictive emergeance
and spread models
including the following
tools and scenarios:
- Global and Regional
prevention
- Early warning
- Surveillance
- Monitoring
Coordination with
international
organisations and third
world countries.
PUB/HEALTH & SOCIO
ECONOMY
AGRO/ECOLOGY
Ecosystème
Regional/local
developpment
landscapes
economical /
social conditions
FOCI
Climat
Vectors
Pathogens
PATHOGENIC CYCLE
Human
activities
hosts
‘‘indicator diseases’’
•Tick-borne Disease –diseases already present in Europe that have shown significant recent
increases in incidence, at least partly due to changes in human behaviour in relation to the
environment.
•Rodent-borne viruses (hanta, arena, cowpox) – widespread but under-reported diseases
within Europe, with strong links with habitat and landscape structures.
•Leishmanioses – persistent on the southern fringes of Europe and beyond (southern
Mediterranean basin), with the potential to expand as environments change.
•West Nile Virus – periodic and occasionally severe local outbreaks, especially on the eastern
fringes of Europe, currently showing strong associations with landscape patterns.
•Malaria – an ancient scourge of Europe, currently now on her southern and eastern fringes,
with the potential for re-emergence following environmental changes.
•Maladies Africaines – new strains of West Nile Virus and new diseases such as Rift Valley
Fever may be introduced to Europe from tropical regions linked by bird and other (e.g. traded
livestock) migratory routes to Europe.
A common approach for all Sub-Projects
WP / Tasks
Patterns
Processes
Landscape,
biotopes and
Habitats
Description of the
environmental components
and habitats
Monitoring of major
environmental events and
their consequences on the
cycles components
Vector Bionomics
and Competence
Inventory, vectorial
capacity and competence
of vector populations
Monitoring introduction,
establishment and spread
of vectors
Public Health and
Human Activities
Public health demography
of the human populations
at risk
Monitoring of significant
population flows between
and in countries
Animal reservoirs
Epidemiological inventory
of the receptive wild and
domestic animal
populations
Monitoring migrations
(avifauna), movements and
transport (livestock) of
the animal reservoirs
African Platform
Leishmaniasis
Malaria
Rodent borne diseases
Tick borne diseases
West Nile Virus
Environmental Change
Biodiversity
Data Management
LR Spatial Modelling
African Platform
Leishmaniasis
Malaria
Rodent borne diseases
Tick borne diseases
West Nile Virus
Disease Modelling
Africa
Platform
Malaria
West Nile
Leishmania
Rodent
borne
Tick
borne
Ecosystem components
studies
WP1: Landscape, habitat, climate
Pattern
Process
WP2: Vector
Pattern
Process
WP3: Public Health
Pattern
Process
WP4: Animal Reservoir
Pattern
Process
WP5: Individual disease
Data management
& Modelling
Data management &
information systems
Low resolution
spatial modeling
WP6 Horizontal
activities
WP6.2
RS tools
Africa
Platform
Process
WP2: Vector
Pattern
Disease transmission
modeling
Malaria
WP1: Landscape, habitat, climate
Pattern
WP6.1 Data
management
West Nile
Rodent
borne
Leishmania
Ecosystem components
studies
Tick
borne
Horizontal integration
Process
WP3: Public Health
Pattern
Process
Environmental
change monitoring
Biodiversity
WP6.3
PhD program
WP4: Animal Reservoir
Pattern
Process
WP5: Individual disease
Data management
& Modelling
Data management &
information systems
Low resolution
spatial modeling
WP6 Horizontal
activities
WP6.2
RS tools
Africa
Platform
Malaria
Process
WP2: Vector
Pattern
Disease transmission
modeling
Process
WP3: Public Health
Pattern
Process
Environmental
change monitoring
Biodiversity
WP6.3
PhD program
Emergence
& spread models
WP1: Landscape, habitat, climate
Pattern
WP6.1 Data
management
West Nile
Rodent
borne
Leishmania
Ecosystem components
studies
Tick
borne
Horizontal integration
WP4: Animal Reservoir
Pattern
Process
WP5: Individual disease
Data management
& Modelling
WP7
Overall
Integration:
Tools
&
scenarios
Data management &
information systems
Low resolution
spatial modeling
WP6 Horizontal
activities
WP6.2
RS tools
Africa
Platform
Malaria
Process
WP2: Vector
Pattern
Disease transmission
modeling
Emergence
& spread models
WP1: Landscape, habitat, climate
Pattern
WP6.1 Data
management
West Nile
Rodent
borne
Leishmania
Ecosystem components
studies
Tick
borne
Horizontal integration
Process
WP3: Public Health
Pattern
Process
WP7
Overall
Integration:
Tools
&
scenarios
Environmental
change monitoring
Biodiversity
WP6.3
PhD program
WP4: Animal Reservoir
Pattern
Process
WP5: Individual disease
Data management
& Modelling
WP8: Training, Dissemination, Management & Coordination
HEALTH/ENVIRONMENT
RESEARCH
of model diseases in a variety of
representative environmental settings
Characterise (new)
transmission cycles
Identify factors
triggering emergence
and spread
Project strategy
TOOLS and POLICIES
Catalogue of ecosystems
and environmental
conditions at risk:
“emerging disease hotspots”
Develop predictive
emergence and spread
models
Develop early warning,
surveillance and
monitoring tools
Identify environmental
changes likely to favour
emergence
Contribute to decision
support and policy making
HEALTH/ENVIRONMENT
RESEARCH
Project strategy
of model diseases in a variety of
representative environmental settings
TOOLS and POLICIES
Characterise (new)
transmission cycles
Identify factors
triggering emergence
and spread
Develop predictive
emergence and spread
models
Identify environmental
changes likely to favour
emergence
EDEN strategy
document
integrated ‘transdisciplinary’
health/environment
approach.
Catalogue of ecosystems
and environmental
conditions at risk:
“emerging disease hotspots”
Develop early warning,
surveillance and
monitoring tools
Contribute to decision
support and policy making
EDEN strategy document
A key deliverable produced by the Steering Committee and with
back-up from the advisory group, specialists with internationally
recognised skills in (i) biodiversity monitoring and assessment, (ii)
environmental change detection, (iii) disease modelling, remote
sensing, image processing and interpretation, and (iv) public health.
The EDEN strategy document will propose an innovative integrated
‘trans-disciplinary’ health/environment approach for the unified
analysis of the various EDEN outputs. The development of such an
approach will be a major breakthrough of EDEN.
Objectives timeframe
1
2
3
4
5
SD
H&E
T&P
Dissemination
SD: EDEN Strategy document
H&E: Health/Environment research
T&P: Tools and policies
External
sources
EDEN Indicator
Diseases
Individual
diseases
models
EDEN Steering
Committee
Advisory
group
integrated models
health-environment
Knowledge Flow
DMEWS
Disease Monitoring &
Early Warning Systems
conclusion
Annex1, chap 4.1 Contribution to the objectives of the sub-priority
“EDEN’s bold ambition is to enable a multi-DMEWS system on a solid scientific
foundation running from the theoretical understanding of the reasons for the
emergence of new diseases in vulnerable ecosystems, through an understanding of
complex disease dynamics, to the practical application of such knowledge to
disease control.
We do not know the precise shape of this future yet: EDEN presents a chance to
Europe to invest in some of the ‘brightest and best’ researchers to ensure success with
this vision, and in doing so to advance significantly the state-of-the-art and put
Europe firmly at the forefront of DMEWS.”