Sensory Receptor Organs Detect Energy or Substances • Sensory receptor organs are organs specialized to detect a certain stimulus. • Receptor cells within the organ convert the stimulus into an electrical signal a “transduction” process. • Receptor organs are very diverse because they specialize in detecting different types of stimuli in the environment. • An adequate stimulus is the type of stimulus to which a sensory organ is particularly adapted. • photic (light) energy for the eye • mechanical energy for touch The Variety of Eyes Classification based on type of information detected by specialized sensory receptors each of which has an adequate stimulus type. Do You Hear What I Hear? Evolutionary influence on auditory perception. What do bees see? Regular photograph Photograph with Ultraviolet filter to simulate bee vision Different types of sensory information comes in on different pathways the so called “Labeled Lines” concept. Receptors in Skin are Transducers They can change mechanical energy into action potentinals. The Structure and Function of the Pacinian Corpuscle as an example of transduction of mechanical to action potentials Intensity Coding correlated to amount “intensity” of stimulus detected by the receptors measured by frequency of action potentials. Sensory Adaptation occurs even with constant stimulation so frequency of action potentials decreases after an initial high frequency at the onset of the stimulus. Sensory information is processed through several levels of Sensory Circuits Somatosensory Receptive Field is the area on the skin with receptors that send touch information to particular neurons in the somatosensory cortex. Representation of the Body Surface in Somatosensory Cortex The Chemical Senses: Taste and Smell • The Human Tongue Discriminates at least Five Basic Tastes • salty, sour, sweet, bitter, umami and maybe • Taste receptor cells are located within taste buds on papillae on the tongue. • Taste cells extend cilia into the taste pore to contact tastants. • Chemicals in the Air Elicit Odor Sensations • Flavor is the perception of taste and smell together. Figure 9.22 A Taste Bud and Taste Receptor Cells Figure 9.21 A Cross Section of the Tongue Salty and Sour Transduction Maybe TRPV1 May require PKD2L1 ion channel Sweet and Bitter Transduction T1R2 + T1R3 T2R 30 different types It’s All a Matter of Taste Buds Number of taste buds and type of T2R receptors determine sensitivity to bitter taste. Is Oleogustus the sixth taste ? • Criteria for “primary tastes,” including that the sensation: • • • • • • 1) has ecological consequence 2) is elicited by a distinctive class of chemicals 3) stems from activation of specialized receptors 4) is detected through gustatory nerves and is processed in taste centers 5) has a quality nonoverlapping with other primary qualities 6) evokes a behavioral and/or physiological response • Oleogustus “fat taste” is triggered by nonesterified fatty acids (NEFA) • medium and long-chain NEFA • oleic acid, linoleic acid or 9-decenoic acid • have a taste sensation that is distinct from other basic tastes Oleogustus: The Unique Taste of Fat. Cordelia A. Running, Bruce A. Craig, and Richard D. Mattes. Chemical Senses, 2015, 1–10. Anatomy and Main Pathways of the Human Gustatory System Chemicals in the Air Elicit Odor Sensations The sense of smell starts with receptor neurons in the nose-within the olfactory epithelium. Three types of cells in the epithelium: – Receptor neurons – supporting cells – basal cells From the receptor cell an apical dendrite extends to the mucosal surface. Cilia emerge from the dendritic knob. An axon extends from the other end of the receptor cell to the olfactory bulb. Anatomy and Main Pathways of the Human Olfactory System Steps in Olfactory Sensory Transduction Different Kinds of Olfactory Receptor Molecules on the Olfactory Epithelium ~ 1000 different receptor proteins which can be divided into four different subfamilies of about 250 receptors each Each subfamily of receptors is synthesized in a separate band of the epithelium. Organization of Odor Projections in the Brain