Chapter 14: The Male Reproductive System Chapter Objectives Male reproductive tract and the function of each part. Contents and functions of semen. Roots pertaining to the male reproductive system. Main disorders of the male reproductive system. Abbreviations used in referring to the reproductive system. Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function (cont’d) epididymis A coiled tube on the surface of the testis that stores sperm until ejaculation (root: epididym/o) erection The stiffening or hardening of the penis or the clitoris, usually because of sexual excitement follicle-stimulating hormone (FSH) A hormone secreted by the anterior pituitary that acts on the gonads. In the male, FSH stimulates Sertoli cells and promotes sperm cell development gamete A mature reproductive cell, the spermatozoon in the male and the ovum in the female glans penis The bulbous end of the penis gonad A sex gland; testis or ovary inguinal canal The channel through which the testis descends into the scrotum in the male Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function androgen Any hormone that produces male characteristics; root andr/o means “male” bulbourethral gland A small gland beside the urethra below the prostate that secretes part of the seminal fluid. Also called Cowper gland. circumcision Surgical removal of the end of the prepuce (foreskin) coitus Sexual intercourse ductus deferens The duct that conveys spermatozoa from the epididymis to the ejaculatory duct. Also called vas deferens. ejaculation Ejection of semen from the male urethra ejaculatory duct The duct formed by union of the ductus deferens and the duct of the seminal vesicle; it carries spermatozoa and seminal fluid into the urethra Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function (cont’d) interstitial cells Cells located between the seminiferous tubules of the testes that produce hormones, mainly testosterone. Also called cells of Leydig (LI -dig). luteinizing hormone (LH) A hormone secreted by the anterior pituitary that acts on the gonads meiosis The type of cell division that forms the gametes; it results in cells with 23 chromosomes, half the number found in other body cells (from the Greek word meiosis meaning “diminution”) penis The male organ of copulation and urination (adjective: penile) pituitary gland An endocrine gland at the base of the brain prepuce The fold of skin over the glans penis; the foreskin prostate gland A gland that surrounds the urethra below the bladder in males and contributes secretions to the semen (root: prostat/o) Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function (cont’d) puberty Period during which the ability for sexual reproduction is attained and secondary sex characteristics begin to develop scrotum A double pouch that contains the testes (root: osche/o) semen The thick secretion that transports spermatozoa (roots: semin, sperm/I, spermat/o) seminal vesicle A saclike gland behind the bladder that contributes secretions to the semen (root: vesicul/o) Sertoli cells Cells in the seminiferous tubules that aid in the development of spermatozoa; sustentacular (sus-ten-TAK-ū-lar) cells spermatic cord Cord attached to the testis that contains the ductus deferens, blood vessels, and nerves enclosed within a fibrous sheath Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Normal Structure and Function (cont’d) spermatozoon Mature male sex cells (plural: spermatozoa) (root: sperm/i, spermat/o) testis The male reproductive gland (plural: testes); also called testicle testosterone The main male sex hormone urethra The duct that carries urine out of the body and also transports semen in the male vas deferens The duct that conveys spermatozoa from the epididymis to the ejaculatory duct. Also called ductus deferens. Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Disorders benign prostatic hyperplasia (BPH) Nonmalignant enlargement of the prostate; frequently develops with age; also called benign prostatic hypertrophy cryptorchidism Failure of the testis to descend into the scrotum epididymitis Inflammation of the epididymis. Common causes are UTIs and STIs. erectile dysfunction A lack of ability to perform intercourse in males because of failure to initiate or maintain an erection until ejaculation; impotence impotence Erectile dysfunction infertility Decreased capacity to produce offspring inguinal hernia Protrusion of the intestine or other abdominal organ through the inguinal canal or through the wall of the abdomen into the scrotum Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Disorders (cont’d) orchitis Inflammation of a testis. May be caused by injury, mumps virus, or other infections. prostatitis Inflammation of the prostate gland. Often appears with UTI, STI, and a variety of other stresses. sexually transmitted infection (STI) Infection spread through sexual activity; also called sexually transmitted disease (STD) and formerly venereal (ve-NE-R-ē-al) disease (VD) (from Venus, the goddess of love) sterility Complete inability to produce offspring urethritis Inflammation of the urethra; often caused by gonorrhea and chlamydial infections Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Key Terms Surgery herniorrhaphy Surgical repair of a hernia prostatectomy Surgical removal of the prostate vasectomy Excision of the vas deferens. Usually done bilaterally to produce sterility. May be accomplished through the urethra (transurethral resection) Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Normal Structure and Function emission The discharge of semen genitalia The organs concerned with reproduction, divided into internal and external components insemination Introduction of semen into a woman's vagina orgasm A state of physical and emotional excitement, especially that which occurs at the climax of sexual intercourse phallus The penis Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Disorders balanitis Inflammation of the glans penis and mucous membrane beneath it (root balan/o means “glans penis”) bladder neck obstruction (BNO) Blockage of urine flow at the outlet of the bladder. The common cause is benign prostatic hyperplasia hydrocele The accumulation of fluid in a saclike cavity, especially within the covering of the testis or spermatic cord phimosis Narrowing of the prepuce’s opening so that the foreskin cannot be pushed back over the glans penis priapism Abnormal, painful, continuous erection of the penis, as may be caused by drugs or specific damage to the spinal cord seminoma A tumor of the testis spermatocele An epididymal cyst containing spermatozoa varicocele Enlargement of the veins of the spermatic cord Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Supplementary Terms Diagnosis and Treatment brachytherapy Radiation therapy by placement of encapsulated radiation sources, such as seeds, directly into a tumor or nearby tissue (from Greek brachy-, meaning “short”) castration Surgical removal of the testes or ovaries. Hormones and drugs can inhibit the gonads, to produce functional castration Gleason tumor grade A system for assessing the severity of cancerous changes in the prostate; reported as a Gleason score Whitmore-Jewett staging A method for staging prostatic tumors; and alternate to TNM staging Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Abbreviations AIDS Acquired immunodeficiency syndrome BNO Bladder neck obstruction BPH Benign prostatic hyperplasia (hypertrophy) DRE Digital rectal examination ED Erectile dysfunction FSH Follicle-stimulating hormone GC Gonococcus GU Genitourinary HBV Hepatitis B virus HIV Human immunodeficiency virus HSV Herpes simplex virus LH Luteinizing hormone Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Abbreviations (cont’d) NGU Nongonococcal urethritis PSA Prostate-specific antigen STD Sexually transmitted disease STI Sexually transmitted infection TPUR Transperineal urethral resection TSE Testicular self-examination TUIP Transurethral incision of prostate TURP Transurethral resection of prostate UG Urogenital UTI Urinary tract infection VD Venereal disease (sexually transmitted infection) VDRL Venereal Disease Research Laboratory (test for syphilis) Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Roots Pertaining to Male Reproduction Root Meaning Example Definition of Example test/o testis, testicle testosterone hormone produced in the testis orchi/o, orchid/o testis anorchism absence of a testis osche/o scrotum oscheal pertaining to the scrotum semin semen inseminate to introduce semen into a vagina sperm/i, spermat/o semen, spermatozoa polyspermia secretion of excess semen Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Roots Pertaining to Male Reproduction (cont’d) Root Meaning Example Definition of Example epididym/o epididymis epididymitis inflammation of the epididymis vas/o vas deferens, vasostomy ductus deferens; also vessel surgical creation of an opening in the ductus deferens vesicul/o seminal vesicle vesiculogram radiograph of a seminal vesicle prostat/o prostate prostatometer instrument for measuring the prostate Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Male Reproductive System • Function: – Produce gametes (reproductive cells) • Generated by meiosis • Number of chromosomes cut in half • Fertilization restores chromosome number – Produce hormones • Aid production of gametes • Used in pregnancy and lactation • Regulate secondary sex characteristics Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins The Testes • Male germ cells (spermatozoa) produced inside • Testes suspended outside body in scrotum • Spermatozoa form within testes starting at puberty • Gonads are stimulated by FSH and LH which are released from the pituitary Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Male Genitourinary System Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Transport of Spermatozoa • Sperm cells stored in epididymis • Ejaculation propels them out through series of ducts – Vas deferens – Ejaculatory duct – Urethra – Penis • Transports both semen and urine • Enlarged at tip to form glans penis Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Formation of Semen • Spermatozoa transported in semen • Thick, whitish fluid containing: – Sperm cells – Secretion from: • Seminal vesicles • Prostrate gland • Bulbourethral (Cowper) glands Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Clinical Aspects of the Male Reproductive System • Infections • Most are sexually transmitted – Most common is caused by bacterium Chlamydia trachomatis – Gonorrhea caused by Neisseria gonorrhoeae – Herpes caused by a virus • Non-sexually transmitted – Mumps caused by a virus, infects testes Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Benign Prostatic Hyperplasia • Prostate gland normally enlarges as men age • Can press on urethra near bladder • Can cause: – Urinary retention – Infection Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Benign Prostatic Hyperplasia (cont’d) • Treatments include: – Medications for relaxing smooth muscle in prostate – Drugs that interfere with testosterone activity – Saw palmetto (herbal remedy) – Prostatectomy (removal of prostate) Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Cancer of the Prostate • Most common malignancy in U.S. men • Third leading cause of cancer-related deaths • May metastasize rapidly • Difficult to remove surgically • Possible treatments – Radiation – Measures to reduce androgens (stimulates prostatic growth) – Chemotherapy Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Testicular Cancer • Represents less than 1% of cancer in men • Appears between ages 25 and 45 with no signs of genetic inheritance • Treatment: – Removal of testis – Radiation – Chemotherapy Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Cryptorchidism • Testes normally descend into scrotum by birth • If not termed cryptorchidism from: – (Crypt/o) hidden – (Orchid/o) testis • May correct itself within first year of life • Must be surgically corrected to avoid: – Sterility – Increased risk of cancer Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Cryptorchidism Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Infertility • Inability or diminished ability to reproduce • Causes include: – Hereditary – Hormones – Related to disease – Exposure to chemical or physical agents – Sexually transmitted diseases • Total inability to reproduce termed sterility • Voluntary sterility done with vasectomy Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Erectile Dysfunction • Also known as impotence • Lack of ability to perform intercourse due to inability to: – Initiate erection – Maintain erection until ejaculation • Causes: – Psychogenic – Physical – Neurogenic – Pharmacological Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Erectile Dysfunction (cont’d) • Possible treatments: – Drugs to dilate arteries in penis to increase blood flow • Sildenafil (Viagra) – Penile vacuum pumps – Penile prostheses Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Inguinal Hernia • Testes descend through inguinal canal • Canal may represent weakness in abdominal wall • Can lead to hernia – Indirect (external) hernia – Direct (internal) hernia – Strangulated hernia • Treatment – Herniorrhaphy (surgery to correct) Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Inguinal Hernia Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 1. The male germ cell, or gamete, is the: (a) ovum (b) testis (c) spermatozoon (d) semen Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 1. The male germ cell, or gamete, is the: (a) ovum (b) testis (c) spermatozoon (d) semen Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 2. Gametes develop in a gonad, which in males is called the: (a) testis (b) seminal vesicle (c) vas deferens (d) penis Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 2. Gametes develop in a gonad, which in males is called the: (a) testis (b) seminal vesicle (c) vas deferens (d) penis Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 3. The main male sex hormone is: (a) estrogen (b) amylase (c) renin (d) testosterone Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 3. The main male sex hormone is: (a) estrogen (b) amylase (c) renin (d) testosterone Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 4. The secretion that transports gametes in males is: (a) bile (b) semen (c) urine (d) pepsin Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 4. The secretion that transports gametes in males is: (a) bile (b) semen (c) urine (d) pepsin Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 5. The gland below the bladder in males is the: (a) adrenal (b) scrotum (c) submandibular (d) prostate Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 5. The gland below the bladder in males is the: (a) adrenal (b) scrotum (c) submandibular (d) prostate Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 6. Protrusion of an organ or tissue through an abnormal body opening is a(n): (a) hernia (b) occlusion (c) stenosis (d) embolus Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 6. Protrusion of an organ or tissue through an abnormal body opening is a(n): (a) hernia (b) occlusion (c) stenosis (d) embolus Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 7. Orchitis is inflammation of the: (a) bladder (b) kidney (c) penis (d) testis Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Pretest 7. Orchitis is inflammation of the: (a) bladder (b) kidney (c) penis (d) testis Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins