Digestion System & Nutrition By: Kreauna Bonner, Shalana Hunter, and Jazelle Jackson http://www.studyblue.com/notes/note/n/nutrition-final/deck/4816060 What is Digestion? Digestion: Is the chemical and mechanical break down of food and the absorption of the resulting nutrients by cells. Mechanical Digestion: Breaks large pieces into smaller ones without altering their chemical composition. Chemical Digestion: Breaks food into simpler chemicals The Digestive System The digestive system consists of the alimentary canal. The alimentary canal extends about 8 meters from the mouth to the anus, and several accessory organs that secrete substances used in the process of digestion into the canal. The Digestion System The Alimentary canal includes: Mouth Pharynx Esophagus Stomach Small intestine Large intestine Rectum Anus Accessory organs include: Salivary glands Liver Gallbladder Pancreas Alimentary Canal The alimentary canal consists of four distinct layers that are developed to different degrees from region to region. These layers are: Mucosa (mucous membrane): surface epithelium, underlying connective tissue, and a small amount of smooth muscle form this layer Submucosa: consists of considerable loose connective tissue as well as glands, blood vessels, lymphatic vessels, and nerves organized into a network called a plexus. Muscular layer: produces movements of the tube Serosa (serous layer): The visceral peritoneum comprises the serous layer, or outer covering, of the tube. Movements of the Tube The motor functions of the alimentary canal are of two basic types: Mixing Movements and Propelling Movements Mixing occurs when smooth muscles in small sections of the tube contract rhythmically Example: When your stomach is full, waves of muscular contractions move along its walls from one end to the other. Propelling includes a wavelike motion called peristalsis. Peristalsis occurs when a ring of contraction appears in the wall of the tube, while this happens the muscular wall just ahead the rings relaxes When the peristalsis waves move along, it will push the tubular contents ahead of it Tube Movement Mixing movements occur when small segments of the muscular wall of the alimentary canal contract rapidly Peristalic waves move the contents along the canal Mouth The Mouth It receives food and begins mechanically reducing the size of solids and mixing them with saliva. The lips, cheeks, tongue, and palate surround the mouth to help with the breakdown of food. Cheeks and Lips The cheeks consist of outer layer of skin, pads of hypodermic fat, muscles associated with the expression of chewing, and inner layers of moist stratified squamous epithelium. The lips are very highly mobile structures. They consists of skeletal muscles and sensory receptors, that are useful in the judgment of temperature and texture of various foods. Mouth (cont.) Tongue The tongue nearly fills the mouth when closed. Mucous membranes cover the tongue. A membranous fold called the frenulum connects the midline of the tongue to the top of the mouth Tongue is also useful because it has the ability of moving food underneath the teeth for chewing. The tongue consists of rough projections called papillae on the surface of the tongue which provides friction, which helps handle the food. Papillae also bare taste buds The roof of the tongue is also known as the posterior region, it is anchored to the hyoid bone Posterior region is covered with round masses of lymphatic tissue these are called lingual tonsils Mouth (cont.) Palate: Forms the roof of the oral cavity, and consist of a hard anterior (hard palate) part and a soft posterior (soft palate) part Soft palate forms a muscular arch which extends posteriorly and downwards as a cone shaped projection called the uvula While swallowing the soft palate and uvula draw upward to prevent food from entering the nasal cavity Palatine tonsils are masses of lymphatic tissue on either side of the tongue that are closely associated with the palate The palatine tonsils lie beneath the epithelial lining of the mouth they protect against infection The Pharyngeal tonsils or adenoids are above the border of the soft palate on the posterior wall of the pharynx. Mouth (cont.) Teeth There are two different sets of teeth during development primary and secondary teeth Primary teeth erupt through the gums between the ages of six months to 2 years old. The secondary teeth usually appear around the age of six years old Salivary glands The salivary glands secrete saliva. Saliva moistens food particles helping to bind them so they can start the process of chemical digestion of carbohydrates. Saliva is a solvent Saliva dissolves foods so that they can be tasted and it helps cleanse the mouth and teeth With in each salivary gland there are two types of secretory cells the Serous cell and the Mucous cell Serous cells produce watery fluid the contains amylase, this enzyme splits starch and glycogen molecules into disaccharides which is the first step of the chemical digestion of carbohydrates. Mucous cells secretes a thick liquid called mucous this liquid binds food particles and lubricates during swallowing. Salivary Glands (cont.) The three major parts of the Salivary Glands are the parotid, submandibular, and sublingual glands Parotid Glands : are the largest of the major Salivary glands each of these glands lies anterior to the ear between the cheek and the masseter muscle. The parotid glands secrete a clear fluid that is rich in amylase. Submandibular Glands: are located in the floor of the mouth on the inside surface of the lower jaw. The secretory cells of the these glands are predominantly serous, containing a few mucous cells. Submandibular glands secrete a viscous fluid than the parotid. Sublingual Glands: is the smallest of the salivary glands are on the floor of the mouth inferior to the tongue. Secretary cells are primarily the mucous type making their secretions thick and stringy. Pharynx and Esophagus Pharynx connects to the nasal and oral cavities with the larynx and esophagus. There are three different parts. Nasopharynx: communicates with the nasal cavity and provides a passageway for air during breathing Oropharynx: is posterior to the soft palate and the inferior to the nasopharynx. It is a passageway for food moving downward from the mouth and for air moving to and from the nasal cavity. Laryngopharynx: just inferior to the orophaynx is a passage to the esophagus. There are three stages of swallowing. Food is mixed with the saliva and forced into the pharynx Involuntary reflex actions move the food into the esophagus Peristalsis transports food to the stomach Pharynx and Esophagus Esophagus is a a straight, collapsible tube about 25 centimeters long, is a food passageway from the pharynx to the stomach The esophagus begins at the bottom of the pharynx and goes down the posterior to the trachea, that passes through the the mediastinum. Circular muscle fibers at the distal end of the esophagus that helps prevent regurgitation of food from the stomach Stomach The stomach receives food, mixes it with gastric juice carries on a limited amount of absorption and moves food into the small intestine. Parts of the stomach The stomach is divided into cardiac, fundic, body, and small intestine The cardiac regions is a small area near the esophageal opening The fundic region which balloons superior to the cardiac portion is a temporary storage area Main part of the stomach lines between the fundic and pyloric portions Pyloric region narrows and becomes the pyloric canal as it approaches the small intestine. At the end of the pyloric canal, the muscular wall thickens, forming a powerful circular muscle, the pyloric sphincter. This muscle is a valve that controls gastric emptying Stomach (cont.) Regulation of Gastric Secretion: gastric glands secrete gastric juice. Gastric juice contains pepsin. This begins the chemical digestion of protein hydrochioricacid and intrinsic factor. The regulation of gastric secretions is the parasympathetic impulses and the hormone gastrin that enhances gastric secretion. Food in the small intestine reflexly inhibits gastric secretions Gastric Absorption: when the stomach absorbs a few substances, such as water and other small molecules Mixing and Emptying Actions: after a meal the mixing movement of the stomach wall acid in producing a semi fluid paste of food particles and gastric juice called chyme. Peristaltic waves push the chyme closer to the pyloric sphincter then the muscles begin to relax, during stomach contractions chyme is pushed little by little into the small intestine Stomach (cont.) The rate of which the stomach empties depends upon the fluidity of the chyme and the type of food present When liquids are passed through the stomach, it is moved along rapidly. Whereas solids stay until they are well mixed with gastric juice Fatty foods will stay in the stomach for three to six hours Foods high in proteins move through more quickly Carbohydrates pass through faster than fats and proteins Pancreas The pancreas also has an exocrine function - secretion of a digestive juice called pancreatic juice The pancreas is closely associated with small intestine. It is located horizontally across the posterior abdominal wall in the C-shaped of the duodenum Pancreatic juice contains enzymes that can split carbohydrates, fats, nucleic acids, and proteins. Pancreatic juice has a high bicarbonate ion concentration that helps neutralize chyme and causes intestinal contents to be alkaline Hormones regulate pancreatic secretion Secretin stimulates the release of pancreatic juice with a high bicarbonate ion concentration Cholecystokinin stimulates the release of pancreatic juice with a high concentration of digestive enzymes Liver The liver is located in the upper right quadrant of the abdominal cavity, just inferior to the diaphragm The right and left lobes of the liver consist of hepatic lobules, the functional units of the gland. Biles canals carry the bile from hepatic ducts The liver mobilizes carbohydrates, lipids, and proteins; stores some substances it filters blood, destroys toxins and secretes bile. The only liver secretion there is is bile that also directly affects digestion. The liver plays a specific part in carbohydrate metabolism by maintaining the normal concentration of blood glucose. Liver cells that are responding to hormones such as insulin and glucagons lower the blood glucose level by breaking down glycogen or by converting noncarbohydrates into glucose Liver (cont.) Most vital liver functions concern protein metabolism. This includes deaminating amino acids forming urea, synthesizing plasma proteins (clotting factors) and converting certain amino acids to other amino acids The liver also stores glycogen, iron, and vitamins A, D, and B12 Macrophages in the liver help destroy damaged red blood cells and phagocytize foreign antigens. The liver also removes alcohol from the blood and secretes bile Bile contains bile salt, bile pigments, cholesterol, and electrolytes. Only the bile salts have digestive functions The gallbladder is a pear-shaped sac located in a depression on the livers inferior surface. Its attached to the cystic duct which in turn joins the common hepatic duct. Liver (cont.) The gallbladder is lined with epithelial calls and has a strong, muscular layer in the wall that stores bile between meals, reabsorbs water to concentrate bile, and contracts to release bile into the small intestine A sphincter muscle controls the release of bile from the common bile duct The sphincter muscle at the base of the common bile duct relaxes as a peristaltic wave in the duodenal wall approaches Small Intestine The small intestine is a tubular organ that extends from the pyloric sphincter to the beginning of the large intestine, with its many loops and coils it fills much of the pancreas and liver It completes digestion of the nutrients in chyme, absorbs the products of digestion and transports the residues to the large intestine The small intestine consists of of three portions: the duodenum, the jejunum, and the ileum The duodenum is 25 centimeters long and 5 centimeters in diameter, lies posterior to the parietal peritoneum and is the most fixed portion of the small intestine The proximal two filths of this portion is the jejunum and the remainder is the ileum A double-layered fold of peritoneal membrane called mesentery suspends these portions from the posterior abdominal wall Small Intestine Diagram Small Intestine (cont.) The wall is lined with villi that greatly increase the surface area and aid in mixing and absorption Secretions from the small intestine include mucus and digestive enzymes. Digestive enzymes split molecules of sugars, proteins, and fats into simpler forms Mechanical and chemical stimulation from chyme causes goblet cells to secrete mucus. Distention of the intestinal wall stimulates parasympathetic reflexes that stimulate secretions from the small intestine Enzymes in microvilli perform the final steps in digestion. Villi absorb monosaccharides, amino acids, fatty acids and glycerol. Monosaccharide are absorbed by the villi through active transport or facilitated diffusion and enter blood capillaries Small Intestine (cont.) Amino acids are absorbed into the villi by active transport and are carried away in the blood Fatty acids are absorbed and transported differently than the other nutrients The small intestine carries on segmentation and peristaltic waves The ileocecal sphincter at the junction of the small and large intestines usually remains closed unless a gastroileal reflex is elicited after a meal. Large Intestine The large intestine absorbs water and electrolytes and forms and stores feces The large intestine consists of the cecum, colon, the rectum, and the anal canal. The anal canal opens to the outside as the anus; it is guarded by an involuntary internal anal sphincter and a voluntary external anal sphincter muscle The large intestinal wall has the same four layers found in other areas of the alimentary canal, but lacks many of the features of the small intestinal mucosa such as villi Fibers of longitudinal muscle are arranged in teniae coli that extend the entire length of the colon, creating a series of pouches Large Intestine (cont.) The large intestine does NOT digest or absorb nutrients, but it does secrete mucus; absorbs electrolytes and water; and contains important bacteria that synthesize vitamins and use cellulose. Peristaltic waves happen only two or three times during the day in the large intestine Defecation is stimulated by a defecation reflex that forces feces into the rectum where they can be expelled. Feces are composed of undigested material, water, electrolytes, mucus, and bacteria. Both the color of feces and its odor is due to the action of bacteria Nutrition and Nutrients Nutrition is the process by which the body takes in and uses nutrients Essential nutrients are those that cannot be synthesized by human cells Carbohydrates, such as sugars and starches, are organic compounds used for sources of energy in the diet. Carbohydrates can be consumed in a variety of ways: starch from grains, glycogen from meat, and disaccharide and monosaccharide sugars from fruits and vegetables. Complex carbohydrates are broken down into monosaccharides Monosaccharides that are absorbed in the small intestine are fructose, galactose, and glucose; the liver converts the first two into glucose Excess glucose is stored as glycogen in the liver then converted into fat and stored adipose tissue The need for carbohydrates varies with a person's energy requirements; the minimum requirement is unknown Nutrition and Nutrients Lipids are organic substances that supply energy for cellular processes and to build structures. Lipids include fats, phospholipids, and cholesterol Most common of lips are triglycerides. Triglycerides are found in plantand animal-based foods. Digestion breaks down triglycerides into fatty acids and glycerol. A normally based human diet varies widely in lipid content. A typical diet consisting of a variety of foods usually provides adequate fats Proteins are polymers of amino acids. Foods rich in protein include meats, fish, poultry, cheese, nuts, eggs, and cereal. Legumes include beans and peas, contain lesser amounts Cells in an adult can synthesize all but eight required amino acids, whereas children can produce all but ten Nutrition and Nutrients Amino acids that the body can synthesize are considered nonessential, whereas those that cannot are essential amino acids This refers to only to dietary intake since all amino acids are required for normal protein synthesize A protein called gliadin in wheat is an example of partially complete protein which does not contain enough lysine to promote growth, but contains enough to maintain life. Nutrition and Nutrients Vitamins are classified in two different basis of solubility, one that involves fats and the other with water Fat-soluble vitamins: this includes vitamins A, D, E, and K. These are carried in lipids and are influenced by the same factors that affect lipid absorption Water-soluble vitamins: this includes vitamins B, and C. B vitamins make up a group and oxidize carbohydrates, lipids, and proteins. C vitamins is the least stable, and widespread in plant foods, and is necessary for collagen production Minerals are elements other than carbon that are essential in human metabolism. Plants usually extract minerals from soil, and humans obtain minerals from plant foods or from animals that have eaten plants Adequate Diets An adequate diet is based upon sufficient energy, essential fatty acids, essential amino acids, vitamins, and minerals that will support optimal growth and maintain and repair body tissues. Because an adequate diet requirements are greatly dependent upon age, sex, growth rate, amount of physical activity, and level of stress, designing a diet adequate for everyone is impossible Because of this a Department of Agriculture in the U.S has created a series of food pyramids based upon age, medical conditions, ethnicity, food preferences, vegetarianism, and weight loss goals. Food Pyramid Adequate Diets There are highly different diets for someone who is a normally active person compared to someone who is athlete such as a weight lifter. Someone who lifts weights on a regular basis would stick to a high protein low carb diet. For example a normally active person would endure around 50 grams of protein a day whereas a weight lifter would consume around 100 grams Diseases/Disorders Appendicitis: Is caused by, in some cases, when small objects block the opening. Which then creates bacteria that grows and causes and infection. It is most common in people 10-30. Symptom is belly pain, pain can become severe while moving coughing or walking. Crohn’s Disease: Caused by inflammation of the digestive (or gastrointestinal) tract. 500,000 people are affected in the U.S which tends to run in families. Symptoms are upset stomach, bouts of diarrehea, and bowel obstruction. Treatments are eating helthy, regular exercise, medications, nutritional supplementation, and surgery. Colitis: Is inflammation of the colon leaving sores, or ulcers, on the inside lining that can bring on frequent bouts of diarreha and abdominal cramps. Usually occurs between the ages of 15 and 30. Possible causes are genetics, environmental factors, and immune system responses. Works Cited Page http://okinawa-diet.com/okinawa_diet/food_pyramid.html http://glencoe.mcgrawhill.com/sites/0218378151/student_view0/chapter15/textbook_images.html http://glencoe.mcgrawhill.com/sites/0218378151/student_view0/chapter15/study_outline.html http://www.everydayhealth.com/health-center/appendicitis.aspx http://www.everydayhealth.com/crohns-disease/index.aspx http://www.everydayhealth.com/ulcerative-colitis/ulcerative-colitiscauses.aspx Shier, David. Hole’s Essentials of Human Anatomy and Physiology. Boston: Mc Graw Hill Higher Education. 2006. 386-420. Print