Systematic Literature Searching VETM 601 Professional Skills UCVM Graduate Students Nov 29, Dec 13 2012 Lorraine Toews MLIS Librarian, Veterinary Medicine ,UC Health Sciences Library libguides.ucalgary.ca/vetmed My background Masters Library & Information Studies (MLIS) U of A UC Library Subject Librarian – academic staff 1997 – 2006 UME, PGME Faculty of Medicine 2006 – pres Faculty of Veterinary Medicine 2011- pres Bachelor of Health Sciences, Faculty of Medicine Adjunct appointment – UCVM Ecosystem & Public Health Co-author reviews Author Registered Nurse - 7 years Workshop Overview Search continuum Standards for systematic searches Search process Developing search questions Selecting databases & search engines Search strategies • Textword vs Subject Heading • Broaden & Focus Searches Saving search strategies Reporting searches Publishing your research Search Continuum Focused search for Comprehensive … search for … Exhaustive search for … Clinical decision support Dissertations Systematic reviews Current awareness Research Proposal Policy reviews Systematic Reviews vs Narrative Reviews Feature Narrative Review Systematic Review Question Often broad Focused clinical question Search Often not specified Comprehensive, explicit search Selection of Studies Often not specified Potentially biased Explicit criteria used to minimize bias Evaluation of Studies Variable, not specified Rigorous, explicit evaluation of studies Synthesis Often not specified Often qualitative Often quantitative Meta-analysis Recommendations Sometimes evidence based Evidence-based if well conducted review Standards for Systematic Literature Search Cochrane Collaboration Handbook http://www.cochrane-handbook.org/ US Institute of Medicine Standards for Systematic Reviews http://www.iom.edu/ Systematic review searches aim to minimize bias by Doing an exhaustive search for all the evidence in … Peer reviewed journal literature Grey literature • • • • • Conference proceedings Dissertations & theses Government documents Data & statistics Professional organization reports Unpublished studies – clinical trial & research in progress registries 1. Translate your Research Question into Searchable Questions 2. Develop Search Terms Ask a Searchable Question How does the metaphylactic use of antimicrobials in beef cattle affect the emergence of antimicrobial resistance in a feedlot setting? Key concepts & Search terms Concepts Search terms metaphylactic OR metaphylaxis metaphylaxis beef cattle OR prophylactic OR prophylaxis cattle OR bovine antimicrobial resistance OR antimicrobial resistance feedlots antibiotic resistance OR AMR Feedlot OR concentrated animal feeding operation OR CAFO Ask a Searchable Clinical Question Among dairy cattle, is the complement fixation test vs the Elisa test more accurate in screening for Johne’s disease? Key Concepts & Search Terms Concepts Search terms P = Population/Species Dairy cattle P = Problem/ Disease I = Intervention ELISA OR enzyme linked immunosorbent assay C = Comparison Intervention Cft OR complement fixation test O = Clinical Outcome Johne’s disease OR paratuberculosis Define Search Limits Publication Date Language Type of document – review, RCT Age group Gender Geographic Location 3. Select Appropriate Databases for Your Topic and Task Veterinary Medicine Interdisciplinary 3.1 Locate journal literature Google Scholar - background, scoping search, cited by - find known article CAB Abs – vet med, animal science PubMed / MEDLINE – medicine, vet med Scopus, Web of Science Citation – multidisciplinary, citation tracking Wildlife & Ecology Studies BIOSIS – basic science Environment Complete - environment Agricola – animal science CAB Abs vs PubMed CAB Abstracts Content Comprehensive index of veterinary medicine journals* Indexes many vet medicine conference proceedings PubMed | MEDLINE Indexes 110 vet med journals + human medicine journals Not index conference proceedings Quality of Indexing Less depth, less consistency than PubMed Consistent, in-depth, granular indexing Search interface More complex than PubMed Easier, more intuitive Evidence-based medicine No Clinical Queries Clinical Queries feature Access Subscription required Free CAB Abstracts Subject Coverage CABI Publishing http://www.cabi.org/default.aspx?site=170&page=1016&pid=125 Some Vet Med Journals in CAB Abs not in PubMed Bovine Bovine Practitioner Cattle Practice Livestock Science UK Vet: Livestock Equine Australian Equine Veterinarian Equine Veterinary Education Journal of Equine Science Journal of Equine Veterinary Science Exotics Exotic DVM Journal of Exotic Pet Medicine Swine Journal of Swine Health & Production Pig Journal Some Vet Med Journals in CAB Abs not in PubMed Poultry Journal of Poultry Science Poultry International Public Health Journal of Veterinary Epidemiology Journal of Veterinary Public Health Wildlife European Journal of Wildlife Research Journal of Wildlife Health Journal of Wildlife Management Other Journal of Veterinary Cardiology CAB Abs, BIOSIS Web of Science Scopus & Web of Science Scopus Web of Science Multidisciplinary Multidisciplinary Citation tracking Citation tracking More journals More conference proceedings 1996 - present 1898 - present Scopus Coverage Scopus Coverage Wildlife & Ecology Studies Subject Coverage Environment Complete Subject Coverage 3.2 Locate conference proceedings CAB Abstracts – vet med IVIS International Veterinary Info System Web of Science Scopus BIOSIS – basic science UC Library Catalogue – selective Interlibrary loan Purchase from Proquest Dissertations Express 3.3 Locate dissertations & theses Proquest Dissertations & Theses Full-text PDFs 1997 – present Can take 1 year to appear in Proquest Interlibrary loan if not in Proquest Purchase Proquest Dissertations - credit card 3.4 Locate data & statistics UC Library Spatial & Numeric Data Services http://library.ucalgary.ca/sands Phone: 403-220-6822 libdata@ucalgary.ca maps@ucalgary.ca Twitter: @UofCLibData 3.6 Locate unpublished clinical trials Cochrane Collaboration Handbook Chap 6.2.3 Unpublished and ongoing studies Clinical trial registries http://handbook.cochrane.org/ Mainly human, but have animal studies related to human disease Off-Campus Authentication Barcode: first 9 digits of barcode on back (leave off last digit) Password/PIN: UCID number leave off zeros at front of number http://thoth.lib.ucalgary.ca/loginhelp.html 4. Search Strategies A Cautionary Note Databases like CAB Abstracts, Scopus … • Do not work like Google • Quality varies • Consistency, depth indexing • Search software functionality • Subject coverage varies • Effort to learn search skills > quality of results Broaden or Focus your Search Concept Search Terms A AND Cft OR complement fixation test “AND” in a concept NARROWS search B elisa OR enzyme linked immunosorbent assay AND C AND “OR” in synonyms within a concept BROADENS search Johne’s disease OR paratuberculosis Strategies to Broaden Searches Reframe your question to make it broader Use broader search terms Remove the least important concept Add synonyms within a concept (Boolean OR) Use truncation in textword searches – therap* retrieves therapy, therapist, therapeutic Apply fewer, or no limits Use the Explode feature (only in CAB Abs, OVID MEDLINE) Use both subject headings & textwords for the broadest search Strategies to Focus Searches Reframe your question to make it narrower Use more specific search terms Add another concept Use less/no synonyms within a concept Use less/no truncation in textword searches Apply more limits Do not use the Explode feature (only in CAB Abs, OVID MEDLINE) Subject Heading vs Keyword Searching Subject Heading Textword |Keyword What is searched? Search subject headings assigned by indexer Search word(s) in title, abstract Advantages Retrieves more relevant results Retrieves new topics in literature + very specific topics Enables use of Explode, Focus features Easier to learn and use Enables retrieval abstract, multi-faceted concepts Disadvantages New terms (eg. New drugs) may not be in subject headings yet Often retrieves more irrelevant records (word match) Searcher must include synonyms, plurals, spelling variations in strategy Search Mode Depends on Task PubMed Default or Advanced Need only the key articles on topic Topic covered by journals indexed in PubMed CAB Abs Multi-Field • Topic not covered in PubMed journals • Need only the key articles on topic • You do not need a comprehensive search CAB Abs or MEDLINE Advanced Need a comprehensive, precise search Your topic is abstract, multi-faceted Search Mechanics Boolean Operators AND, OR, NOT (see separate slide) Parentheses ( ) Enclose synonyms for a concept in parentheses Search boxes in CAB Abs Multi-Field does automatically Exact phrase search Varies depending on database Many databases use quote marks “_” around a phrase Truncation Asterisk at end of word stem retrieves plurals, word variants - therap* retrieves therapy, therapist, therapeutic Boolean Operators AND OR NOT Connects concepts Connects synonyms or similar terms within a concept Excludes all records that contain the term after NOT Finds records with EITHER or BOTH search terms Narrows search Broadens search Dementia NOT Alzheimers Finds records with ALL search terms Narrows search Dementia AND treatment Dementia OR Alzheimers Use with care Textword Search (OVID Multi-Field) CAB Abstracts CAB Abstracts Record Textword Search Multi-Field OVID Find Review articles in CAB Abstracts Type the following in the search box: Exp Reviews/ or meta-analysis/ Combine with your final subject search set using AND Subject Heading Search (OVID Advanced) CAB Abstracts CAB Abstracts Record CAB Abstracts Record Subject Heading search (OVID Advanced Search) searches this part of record Subject Heading Search OVID Advanced Purpose of Subject Headings Account for synonyms, plural, alternate spelling Increased Relevance Purpose of Subject Headings Use the Explode function Purpose of Subject Headings Retrieval of abstract, multi-faceted topics Getting Full-Text Articles E-Journals Full-text Articles SFX SFX Citation linker Links database search results with full-text articles Indicates if item is available in print in UC Library Interlibrary loan link if UC Library not have online or print Interlibrary Loan Order articles UC Library does not have Journal articles desktop delivery 2-4 business days Must have email in library patron database Full-Text Article: Via Database SFX Link I Interlibrary Loan Link on SFX in Database Interlibrary Loan Login Interlibrary Loan Journal Request 5. Save Search Strategy http://www.library.ualberta.ca/uploads/HealthSciences/documents/OvidSP SaveHistory.pdf Save Search History OVID Save Search History OVID Save Search History OVID Save Search History PubMed Save Search History PubMed Save Search History PubMed 6. Save and Format References Reference Management Software Support http://library.ucalgary.ca/citing-and-writing-health-sciences 7. Search Reporting Standards Why does reporting the search matter? In reviews – literature search is the data collection method If search incomplete or biased > quality, conclusions of review in doubt Transparent, complete reporting assists consumer of research in assessing quality, validity of review Best Practice Reporting Standards PRISMA Preferred Reporting Items of Systematic reviews & Meta-Analyses http://www.prisma-statement.org/history.htm Cochrane Collaboration Handbook http://www.cochrane-handbook.org/ Institute of Medicine Standards for Systematic Reviews http://www.iom.edu/ Equator Network http://www.equator-network.org/ Reporting the Search in Methods section Describe all information sources searched Databases with dates of coverage, limits Grey literature sources Reference lists, hand searches Contact with study authors to identify additional studies Date last search done Full electronic search strategy One database > All databases …such that it could be repeated Flow diagram PRISMA Flow Diagram 8. Publish Your Research Publish Your Research Instruction to Authors Check online journal or Google journal website Journal impact factors Journal Citation Reports database LCR Open Access Author’s Fund Helps pay fees to publish in OA journals How can I as a librarian help you? As a Consultant … advise you on … Choice of databases Optimizing search strategies for your purpose Choosing & using reference management software In the future … as a Co-author … International Council Medical Journal Editors – Authorship http://www.icmje.org/ethical_1author.html Develop, conduct reproducible search, minimize bias Document search strategies, archive references Report search in Methods section & flow diagram Review final draft article Need Help? Contact Lorraine Toews MLIS Veterinary Medicine Librarian Health Sciences Library ltoews@ucalgary.ca | 403.220.3750 libguides.ucalgary.ca/vetmed Health Sciences Library Information Desk hslibr@ucalgary.ca | 403.220.6857 M-F 8 am – 4:30 pm (general help) Your feedback, please How did you find today’s workshop? libguides.ucalgary.ca/vetmed VETM601 Grad Student workshop evaluation