Psychopharmacology
[Instructor name]
[Class name section number]
Overview
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Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
Introduction
Psychoactive Drugs
 Communication between neurons
Neurotransmitter Activity
 Agonists – increase
 Antagonists – decrease
Side Effects
Overview
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Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
Pharmacokinetics
Drug effects in the body
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Absorption
Distribution
Metabolism
Excretion
Overview
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Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
Drug Administration
Absorption
 Slowest: Oral
 Fastest: Intravenous/Inhalation
Rapid Absorption =
high abuse potential
Overview
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•
•
Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
Drug Metabolism
 Liver enzymes
 Repeated exposure  Tolerance
 Enzyme induction
 Dangers of grapefruit juice
Overview
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Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
Treatment Approaches
Pharmacology + Therapy
= Most Effective
Medication can be
problematic due to
individual variations.
Discussion
What is the best
treatment for depression?
Overview
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Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
Juveniles
and Psychopharmacology
 High prevalence  Increase in diagnoses
 Difficult to prescribe and research
The Elderly and
Psychopharmacology
 Rapidly aging population
 Polypharmacy
 Risks
Overview
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Introduction
Pharmacokinetics
Drug Administration
Drug Metabolism
Treatment Approaches
– Discussion
• Special Populations and Psychopharmacology
• Activity
SSRIs, Suicidality, Violence, and
Mania
 Why doesn’t everyone
just take a “happy pill”?
 Serious side-effects
 What are other barriers
to drug therapies?
Medication Adherence
Easy as can be… right?
Diagnosis: HIV
Treatment: Kool-Aid
packets/tic-tac mints
Must adhere to the
assigned treatment
protocol
What will make treatment
easier/harder?
Photo Attribution
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