Supply Chain Modeling: Analysis of Demand Variability and Volumetric Capacity Needs for Contraceptives and MCH Products James Gibney Anabella Sánchez Carlos Lamadrid February 20, 2009 Agenda Introduction: Overview of Unmet Need and Areas of Interest Part A: Volumetrics of Guatemala’s Integrated Supply Chain Part B: Effect of Demand Variability on Contraceptive Logistics Introduction: Low Unmet Demand in 2007 For Contraceptives – But Analysis Still Needed to Ensure Success in 2008/9 100% Observation: No significant stock-out problems existed in 2007 for contraceptives 1% 3% 2% 1% 3% 1% 1% 6% 3% 90% 80% 70% 60% 99% 97% 98% 97% 100% 100% 100% 99% 100% 100% 100% 100% 99% 94% 99% 97% 40% 30% 20% 10% Guatemala Total Jutiapa Consumption Totonicapán Unfulfilled Demand Source: MSPAS National RH Program, “Real Demand for Contraceptive Methods (2007)” Sololá Or al s s Inj ec t abl e IUD oms Cond Or al s s Inj ec t abl e IUD oms Cond Or al s s Inj ec t abl e IUD oms Cond Or al s s Inj ec t abl e IUD 0% oms B. What is the effect that variability has on the system? Are stock-outs being avoided due to high level of emergency orders? 50% Cond Areas of Interest: A. Given the integrated supply system, what are the volume requirements needed to ensure full supply for contraceptives and MCH products? Part A: Volumetrics of Guatemala’s Integrated Supply Chain Background: With little exception, the distribution network (warehousing and transport) of products in Guatemala’s public health system is integrated. To better understand the volume capacity needs of this system, data on all products from Jutiapa and Totonicapán was analyzed. A special focus was placed on contraceptives and MCH products. Questions this section answers: 1. In terms of volumes, what does the average monthly demand for all products that flow through a DAS warehouse look like? How does this differ for health centers, health posts, NGO’s, and hospitals? What are the products that take up the most space? 2. What are the space requirements needed for the family planning products? How do these products compare to each other? What are the different requirements per SDP site type? How to they compare to non family planning products? 3. What are the space requirements needed for the MCH products? How do these products compare in space needs to each other? How to they compare to non MCH products? Volumes of Product Types in the Integrated System Volume by % of Average Monthly Demand -- All Products 100% • Contraceptives represent less than 1% of volume for Totonicapán and 3% for Jutiapa 0.5% 1.3% 3.1% 2.3% 32.0% 28.4% 30.1% 66.6% 68.5% 67.6% Health Posts Health Centers 0.8% 0.6% 90% 29.5% 38.4% 80% 33.6% 70% 60% • Difference is attributed to higher demand of condoms in Jutiapa 50% 40% 69.9% 60.8% 30% • MCH accounts for approximately 1/3 and other products take 2/3 of volume capacity 65.8% 20% 10% 0% Health Posts and Health Centers Health Posts Jutiapa Other Products Source: MSPAS Logistics Module (January 2007 to April 2008) Health Centers Totonicapán Maternal & Child Health Contraceptives Health Posts and Health Centers Volumetric Composition of Average Monthly Demand By Products (Combined Average Monthly Real Demand for Totonicpán and Jutiapa) • • 80% volume • • Table provides 105 products Contraceptives are highlighted blue, Condoms take 1.3% of total Volume composition follows 80/20 rule Acetaminofen syrup and Bromexina take approx. 20% of volume Volume (cubic cm) Requirements of Average Monthly Demand • • Jutiapa has double the capacity need at SDP’s than Totonicapán In Totonicapán Health Posts require more volume capacity than health centers for MCH and Other Drugs, but not Contraceptives 253,399 8,000,000 7,000,000 89,559 2,309,746 6,000,000 2,182,770 5,000,000 21,660 4,000,000 1,187,586 • In Jutiapa, the Health Centers require more volume capacity for all product types, with Contraceptives requiring significantly more volumetric capacity (approx. 3x) 3,000,000 5,565,604 25,633 1,286,735 4,540,039 2,000,000 2,814,298 2,035,063 1,000,000 Health Posts Health Centers 27,321 14,177 NGOs Hospital Health Posts Jutiapa Other Products Source: MSPAS Logistics Module (January 2007 to April 2008) Health Centers 15,984 3,287 NGOs Hospital Totonicapán Maternal & Child Health Contraceptives Contraceptive Volumes – Monthly Demand Averages For SDP Types •Percentages show relative capacity needs for storage and transport •Commonalities between Jutiapa and Totonicapan: •Same order of magnitude (Hospitals, then NGO’s, then Health Posts, then Health Centers) •Hospital percentages most similar •Health Post percentages are 2nd most similar •Differences between Jutiapa and Totonicapan 100% 90% 80% 3.7% 7.1% 4.9% 24.0% 23.3% 70% 60% 32.5% 50% 40% 30% 65.9% 20% •Totonicapan higher relative flow to NGO’s •Jutiapa higher relative flow to Health Centers (almost 2 times that of Totonicipan) 38.5% 10% 0% Jutiapa Health Centers Totonicapán Health Posts Source: MSPAS Logistics Module (January 2007 to April 2008) NGOs Hospital For the contraceptives part of the integrated order (1%-3% of total volume, what is the volumetric composition by product? Volume by % of Average Monthly Demand -- Contraceptives 100% 0.0% 0.6% 11.6% 7.7% 90% 0.4% 8.8% 3.5% 0.0% 17.3% 0.0% 9.2% 5.0% 0.0% 3.9% 10.0% 19.6% 25.7% 36.9% 31.4% 22.1% 36.3% 70% 6.9% 25.6% 12.4% 80% 0.5% 33.2% 42.1% 39.7% 19.0% 60% 27.4% 51.1% 21.0% 50% 30.6% 24.1% 22.7% 79.3% 40% 71.3% 67.4% 30% 37.6% 55.4% 48.7% 43.4% 20% 42.6% 31.6% 32.5% 31.8% 10% 38.7% 13.4% 0% Health Posts Health Centers Health Hospital Posts and Health Centers NGOs All Sites Jutiapa CONDOM Health Posts Health Centers Health Hospital Posts and Health Centers NGOs Totonicapán LOFEMENAL Source: MSPAS Logistics Module (January 2007 to April 2008) DEPO PROVERA IUD All Sites What is the Average Monthly MCH Demand By Volume? Totonicapan - MCH Average Monthly Demand by Volume Jutiapa - MCH Average Monthly Demand by Volume 100% LIDOCAINA CLORHIDRATO (SIMPLE) 2 % Vial 90% 80% 70% 60% 50% 40% LIDOCAINA CLORHIDRATO (SIMPLE) 2 % Vial 100% ALBENDAZOL 200 mg Tableta ACIDO FOLICO 5 mg Tableta 90% ALBENDAZOL 200 mg Tableta 7.7% 4.5% 9.1% 11.1% 11.6% 13.5% 5.2% 3.8% 8.7% 13.3% 11.5% 12.5% 9.5% 9.1% 11.8% ACIDO FOLICO 5 mg Tableta PRENATALES 0 Sin Concentración Gragea ALBENDAZOL 200/5 mg/ml Frasco suspensión HARTMAN (RINGER LACTATO) 1000 ml Bolsa/Frasco 6.1% 6.6% 70% AMOXICILINA 500 mg Tableta ACETAMINOFEN 500 mg Tableta 14.4% 80% 60% 50% 40% 6.7% 7.5% 11.0% 11.6% 7.6% 4.6% 5.6% ALBENDAZOL 200/5 mg/ml Frasco suspensión 8.0% AMOXICILINA 500 mg Tableta 5.1% AMOXICILINA + ACIDO CLAVULANICO 125/5 mg/ml Frasco suspensión 9.6% ACETAMINOFEN 500 mg Tableta 10.3% AMOXICILINA + ACIDO CLAVULANICO 250+62.5/5 mg/ml Frasco suspensión 5.2% 10.1% 12.6% 13.0% PRENATALES 0 Sin Concentración Gragea ERITROMICINA 250/5 mg/ml Frasco suspensión 30% TRIMETROPRIMA SULFAMETOXAZOL 40-200/5 mg/ml Frasco suspensión 20% 30.5% 30.8% 30.2% 10% SALBUTAMOL 2/5 mg/ml Frasco Jarabe AMOXICILINA 250/5 mg/ml Frasco suspensión SALES DE REHIDRATACION ORAL 55.8 g Sobre 0% Health Posts Health Posts and Health Centers Health Centers ACETAMINOFEN 120/5 mg/ml Frasco Jarabe SALBUTAMOL 2/5 mg/ml Frasco Jarabe 30% 20% HARTMAN (RINGER LACTATO) 1000 ml Bolsa/Frasco 34.3% 36.8% 31.5% 10% TRIMETROPRIMA SULFAMETOXAZOL 40200/5 mg/ml Frasco suspensión ACETAMINOFEN 125/5 mg/ml Frasco Jarabe ERITROMICINA 250/5 mg/ml Frasco suspensión AMOXICILINA 250/5 mg/ml Frasco suspensión 0% Health Posts Health Posts and Health Centers Health Centers Acetaminofen takes up over 30% in both Departments SALES DE REHIDRATACION ORAL 55.8 g Sobre ACETAMINOFEN 120/5 mg/ml Frasco Jarabe Effect of Demand Variability on Contraceptive Logistics Background: Given the complexity of large logistical networks, such as the MSPAS system, the effect of high variability on a supply chains can be both significant and hard to measure. Accordingly, it is necessary to measure the variability levels and use advanced analysis methods, such as modeling, to determine the effect. Questions this section answers: 1. Does the use of 3 months historical averages in making orders reduce the variation to insignificant amounts? 2. How does variability effect service levels? Can there still be a stock-out even if 1/3 min/max levels are followed? Does an increase in variability increase the propensity for emergency orders? Does it increase the propensity to be overstocked? Variability in Contraceptive Monthly Real Demand Observations: • Real demand changes significantly on a monthly basis • Jutiapa shows lowest variability in all products • High IUD variability partially attributed to low order amounts (ie. change from 4 to 8 represents 100%) Average Change in Monthly Real Demand for 2007 Jutiapa Totonicapan Solola 31% 37% orales 30% 18% inyectable 39% 14% Ramifications: • Variability levels can significantly effect service rates of logistics system, even if system follows the min/max ordering system • Causes of Variability should be addressed – Are reporting procedures being followed – or are there really high swings in real demand? 101% 99% tdecobre 91% 28% 29% condones 15% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% 110% Does Using 3-Month Historical Average Smooth-away Variability? • • • • Table below compares projected demand based on 3 month historical averages to the actual demand for 2007 Red highlights represent projected under-estimating by more than 20% Yellow highlights represent projected demand over-estimating by more than 20% Results: 50% of the time the projected was either over or under by more than 20%. Using projections based on 3-months historical data does not necessarily remove variability. Complexity of system requires the use of advanced supply chain modeling software. BR E E IEM BR VIE M RE TU B SE PT IEM B -23% 22% 3% -8% -5% -63% -10% -22% 5% 44% 2% 8% -21% -64% -8% -13% 13% 0% 1% 13% 46% 700% 64% 104% Totonicapan condones tdecobre inyectable orales -17% -47% -24% -50% -12% 11% 12% 27% 7% 33% -17% -4% 4% 22% -10% -5% 35% -70% 28% 10% -18% -41% -23% -19% -26% 267% 19% -6% -47% -22% -13% -8% 171% 67% 32% 29% 88% 67% 19% 32% Solola condones tdecobre inyectable orales 52% -70% -11% -8% -3% 33% 31% 44% 9% -33% 24% 31% 18% 0% -9% -10% 7% -10% -14% -31% 50% -39% -61% -5% -12% -20% -37% 27% -17% 8% -77% 6% 4% 10% 157% -23% 4% 22% 97% AB MA DIC -12% 183% 7% 13% NO 5% 33% -7% 2% OC AG OS TO JU 3% 0% 5% 51% LIO NIO JU -13% -38% -11% -40% MA condones tdecobre inyectable orales RIL Jutiapa RZ YO O RE Projected Demand as Percentage of Actual Demand For Aggregated 2007 Quantities *Projected amounts calculated using average of previous 3 months Modeling The Department of Sololá Structure • 1 National Warehouse • 1 Department Warehouses • 10 District Warehouses • 33 Health Centers • 10 NGOs • 1 Hospital Rules • Products • Inventory Policies • Sourcing Policies • Transportation Policies Effect of Variability on Sololá Health Center Condom Stock Outs and Emergency Orders Scenario Outputs 25% Variability in Monthly Demand for Condoms 500 Inventory Stock Out Periods – no variability scenario – 0 – 25% variability scenario – 1 – 50% variability scenario – 5 Instances Crossing Above Max (overstocked) – No variability scenario – 0 – 25% variability scenario – 5 – 50% variability scenario – 2 Instances Crossing Below Min (emergency order) – No variability scenario – 0 – 25% variability scenario – 8 – 50% variability scenario – 6 400 300 200 100 0 Aug-07 Nov-07 Feb-08 May-08 Aug-08 Nov-08 Feb-09 May-09 Aug-09 (Settings: 106 condoms/month; 1/3 month min/max; 2 year period, reorder quantity based on previous 3 month demand) 50% Variability in Monthly Demand for Condoms 500 500 400 400 300 200 100 0 Aug-07 Nov-07 Feb-08 May-08 Aug-08 Nov-08 Feb-09 May-09 Aug-09 Inventory Inventory No Variability in Monthly Demand for Condoms 300 200 100 0 Aug-07 Nov-07 Feb-08 May-08 Aug-08 Nov-08 Feb-09 May-09 Aug-09 How variable is the data? Examples of condom real demand - Jutiapa Agua Blanca - Health Center 450 Mean: 214 Standard Deviation: 103 (48% of mean) Asunción Mita - Health Center 4500 3500 300 3000 250 2500 200 2000 150 1500 100 1000 50 500 0 0 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 4000 350 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 400 Mean: 2,564 Standard Deviation: 826 (32% of mean) Source: MSPAS Logistics Module data Atescatempa - Health Center 1800 Mean: 1,059 Standard Deviation: 311 (29% of mean) 1600 1400 1200 Jutiapa - Health Center 4000 Mean: 2,245 Standard Deviation: 709 (32% of mean) 3500 3000 2500 1000 800 600 2000 1500 200 500 0 0 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 1000 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju lAu 07 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 400 How variable is the data? Examples of depo real demand - Jutiapa Moyuta - Health Center 300 Mean: 170 Standard Deviation: 37 (22% of mean) Yupiltepeque - Health Center 100 Mean: 73 Standard Deviation: 11 (15% of mean) 90 250 80 70 200 60 150 50 40 100 30 20 50 10 0 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 0 Source: MSPAS Logistics Module data Comapa - Health Center 200 Mean: 156 Standard Deviation: 14 (9% of mean) 180 160 140 120 El Adelanto - Health Center 140 Mean: 79 Standard Deviation:21 (26% of mean) 120 100 80 100 80 60 60 40 40 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 0 20 0 Ja n0 Fe 7 b0 M 7 ar -0 Ap 7 r0 M 7 ay -0 Ju 7 n07 Ju l-0 Au 7 g0 Se 7 p0 O 7 ct -0 N 7 ov -0 D 7 ec -0 Ja 7 n0 Fe 8 b0 M 8 ar -0 Ap 8 r08 20 Questions?