INDO-U.S. VACCINE ACTION PROGRAM (VAP) INITIATIVE ON TUBERCULOSIS (TB) RESEARCH: REGIONAL PROSPECTIVE OBSERVATIONAL RESEARCH FOR TUBERCULOSIS Letter of Intent (LOI) Template DEADLINE FOR SUBMISSION: FRIDAY, JUNE 15, 2012, 5:00 PM US EASTERN DAYLIGHT TIME (EDT) E-MAIL: TBCOHORT@CRDFGLOBAL.ORG GENERAL PROJECT INFORMATION Application Type (please select ONE): dCRU fCRU Application Title: INDIAN PRINCIPAL INVESTIGATOR INFORMATION Last Name: First: Middle: Current Position at your Institute: Institute Name: Street Address: Apartment/Unit/Office #: City: State: Phone: E-mail Address: Highest Degree Earned: Postal Code: Field of Degree: Year Awarded: U.S. PRINCIPAL INVESTIGATOR INFORMATION Last Name: First: Middle: Current Position at your Institute: Institute Name: Street Address: Apartment/Unit/Office #: City: State: Phone: E-mail Address: Highest Degree Earned: Postal Code: Field of Degree: Year Awarded: ADDITIONAL PERSONNEL Please list information for other key personnel on the Indian and U.S. research teams (Please copy the table for additional team members) Team Member 1: Indian Participant U.S. Participant Full Name: Current Position: Institute: E-mail Address: Highest Degree Awarded: Field of Degree: Year Awarded: Description of Participant’s Role on Project (2-3 sentences): 1 INDO-U.S. VACCINE ACTION PROGRAM (VAP) INITIATIVE ON TUBERCULOSIS (TB) RESEARCH: REGIONAL PROSPECTIVE OBSERVATIONAL RESEARCH FOR TUBERCULOSIS Team Member 2: Indian Participant U.S. Participant Full Name: Current Position: Institute: E-mail Address: Highest Degree Awarded: Field of Degree: Description of Participant’s Role on Project (2-3 sentences): Year Awarded: Narrative: Instructions: In the spaces below, please provide thorough but brief responses to each component of the LOI narrative. Your narrative responses may not exceed four (4) pages total (not including team member/project information requested above) and must be completely contained inside the text boxes. All answers must be typed, in English, single-spaced, with one-inch margins on all side and no less than Arial 10pt font. 1. Summary Statement: In one concise paragraph, summarize all relevant aspects of the project, with special attention to its objectives, methods, and potential results. 2. Background/Rationale: This should include a problem statement and a brief description of the current conditions in your area 3. Primary Objectives for both clinical and fundamental research aspects of the proposal: (including how these objectives relate to the objectives of the Program) 2 INDO-U.S. VACCINE ACTION PROGRAM (VAP) INITIATIVE ON TUBERCULOSIS (TB) RESEARCH: REGIONAL PROSPECTIVE OBSERVATIONAL RESEARCH FOR TUBERCULOSIS 4. Description of the proposed research site: 5. Description of the Cohort: 6. Brief research study design: (including the proposed collaboration and how the combined competences of each research team will contribute to the overall project plan) 7. Overall Budget Estimate: (*Note: For the purposes of the LOI, the budget estimate should be 2-3 lines only. At this time, applicants are not required to submit a detailed budget) We hereby certify that all information contained in this document is accurate to the best of our knowledge. We understand that knowingly submitting misrepresented or falsified information may be grounds for rejection of our application and could jeopardize our eligibility to this and future CRDF Global, NIH, and DBT programs. Indian Principal Investigator Signature: _________________________________ Date: U.S. Principal Investigator Signature: __________________________________ Date: 3 INDO-U.S. VACCINE ACTION PROGRAM (VAP) INITIATIVE ON TUBERCULOSIS (TB) RESEARCH: REGIONAL PROSPECTIVE OBSERVATIONAL RESEARCH FOR TUBERCULOSIS