DIRECTIONS FOR ITEMS 1-100: For each item, select the best answer to the question or response to complete the statement from the four provided. l. Maternal administration of which of the following tocolytic agents is MOST likely to be associated with an increased risk of hypoglycemia in the neonate? (A) (B) (C) (D) 2. When discussing fetal circulation, it is common to consider combined (right and left) ventricular output. On average, the approximate combined ventricular output flow through the ductus arteriosus is (A) (B) (C) (D) 3. 10%. 25%. 45%. 70%. A 69-year-old woman is scheduled for total hip replacement. When she arrives, she has severe dyspnea after her walk from the waiting room and insists on sitting upright. She has been taking an angiotensin-converting enzyme inhibitor and a diuretic since her myocardial infarction (MI) 6 months earlier. Her SpO2 is 87% on room air, her blood pressure is 137/67 mm Hg, and her heart rate is 114 beats/min and regular. You suspect she has an acute exacerbation of her chronic heart failure (HF). Which of the following would MOST likely confirm the diagnosis? (A) (B) (C) (D) 4. Nifedipine Terbutaline Indomethacin Magnesium sulfate B-type natriuretic peptide (BNP, also known as brain natriuretic peptide) determination Chest radiograph Electrocardiogram (ECG) C-reactive protein determination Forty-eight hours after a left upper lobectomy the patient develops dyspnea and a massive air leak via his chest tube. The diagnosis of a bronchopleural fistula is established, and he is scheduled for a thoracotomy for closure of a bronchial stump leak. Which of the following is MOST likely to be indicated in the management of this patient? (A) (B) (C) (D) Placement of a thoracostomy tube on the right Left-sided double lumen tracheal tube Continuous positive airway pressure (CPAP) to the operative lung Extubation in the operating room at the end of the procedure 5. A patient with an object embedded in the plantar surface of the medial forefoot is scheduled for foreign-body removal. Which of the following nerves is MOST important to anesthetize for this procedure? (A) (B) (C) (D) Deep peroneal nerve Superficial peroneal nerve Sural nerve Posterior tibial nerve 6. When transporting spontaneously breathing patient, which of the following semiopen breathing systems with differing positions for the fresh gas flow (FGF) inlet and adjustable pressure-limiting (APL) valve would be MOST efficient at preventing rebreathing? 7. Which of the following is MOST likely to represent an absolute indication that an anesthesia machine is obsolete according to the American Society of Anesthesiologists Guidelines for Determining Anesthesia Machine Obsolescence? (A) (B) (C) (D) 8. Presence of a vaporizer in which clockwise rotation of the rotary concentration dial results in a decreased concentration of volatile anesthetic Presence of connectors in the scavenging system that are 30 mm in diameter Notification by the manufacturer that it will no longer provide service for the anesthesia machine Absence of a vaporizer interlock system Which of the following is the MOST appropriate lasting interval for infant formula in an otherwise healthy 4-month-old infant scheduled for elective inguinal herniorrhaphy? (A) (B) (C) (D) 9. Which statement about intraoperative anaphylaxis is MOST likely true? (A) (B) (C) (D) 10. It occurs most commonly within minutes of anesthesia induction. A rash is present in all severe cases. An elevated tryptase level occurs only with an anaphylactic reaction. Anesthesia induction agents are the most common class of drugs causing this reaction. A 32-year-old man presents for knee surgery. He reports an allergy to cephalexin. After induction of general anesthesia, he inadvertently receives l g of cefazolin intravenously. Within 2 minutes his blood pressure drops from 128/72 mm Hg to 64/30 mm Hg. Ventilation is difficult due to bronchospasm. Immediate administration of which of the following medications is MOST appropriate? (A) (B) (C) (D) 11. Two hours Four hours Six hours Eight hours Hydrocortisone Vasopressin Epinephrine Diphenhydramine Which of the following graphs BEST represents the flow-time and pressure-time graphs for pressure support ventilation? 12. Which of the following is the MOST accurate formula to calculate the pulmonary vascular resistance index? Where MAP = mean arterial pressure CVP = central venous pressure CI = cardiac index MPAP = mean pulmonary artery pressure PAOP = pulmonary artery occlusion pressure SVI = stroke volume index l3. Regional anesthesia is planned for the performance of a cesarean delivery. Blockade of which of the following dermatome ranges is MOST likely to provide adequate anesthesia for cesarean delivery? (A) (B) (C) (D) l4. T4 to S4 T2 to Ll T8 to S4 T3 to L5 Which of the following nondepolarizing neuromuscular blockers is MOST likely to produce histamine induced bronchospasm? (A) (B) (C) (D) Vecuronium Atracurium Cisatracurium Rocuronium 15. Which statement about epidural labor analgesia and its relationship to maternal temperature during labor is MOST likely true? (A) (B) (C) (D) 16. A 57-year-old female with a history of open-angle glaucoma presents to the preoperative clinic for anesthesia consultation. Her glaucoma is medically managed with daily administration of a topical beta- blocker and parasympathomimetic eye drops. Which statement about the anesthetic management of this patient with open-angle glaucoma is MOST likely true? (A) (B) (C) (D) 17. Epidural analgesia is associated with a higher incidence of neonatal sepsis. Epidural analgesia typically results in a decrease in maternal core temperature. Epidural analgesia is associated with an increased risk of maternal fever (temperature >38°C) during labor. An increase in maternal temperature does not typically begin until 3 hours after initiation of epidural analgesia. Use of topical beta-blockers can result in exaggerated hypotension. Use of a defasciculating dose of nondepolarizing neuromuscular blocking agent prior to induction will reliably prevent increases in intraocular pressure associated with succinylcholine administration Parasympathomimetics should be stopped during the perioperative period. The use of atropine during the perioperative period is strictly contraindicated. A central venous catheter is being placed via the basilic vein to allow aspiration of air during a sitting craniotomy. The electrocardiographic (ECG) V lead is being used to determine position of the catheter. The ECG signal originates from the middle orifice of a multiorifice catheter. Which of the following tracings BEST indicates that the middle orifice of the catheter is in the desired position? l8. A 53-year-old woman presents to the preoperative anesthesia clinic for evaluation. She is scheduled to undergo elective parathyroidectomy for primary hyperparathyroidism. She is complaining of polyuria, polydipsia, vomiting, and muscle weakness. Administration of which of the following would he MOST appropriate at this time? (A) (B) (C) (D) l9. Which of the following is LEAST likely to be present in a patient with systemic lupus erythematosus (SLE)? (A) (B) (C) (D) 20. Initiating skin surface warming Warming intravenous fluids in the operating room Using an airway humidifier Warming the anesthesia circuit A healthy subject has indwelling arterial catheters simultaneously transducing pressure from the brachial, radial, femoral, and dorsalis pedis arteries. Which of the following catheters is likely to record the HIGHEST systolic pressure? (A) (B) (C) (D) 22. Pulmonary hypertension Cornary artery disease Renal dysfunction Thrombocytosis A 75-year-old woman is scheduled to undergo a simple abdominal hysterectomy. Which of the following is MOST effective in preventing hypothermia in this patient? (A) (B) (C) (D) 21. Hydrocortisone Hydrochlorothiazide Normal saline infusion Calcitonin Brachial Radial Femoral Dorsalis pedis Which of the following medications is MOST likely to be contraindicated in patients with pulmonary hypertension? (A) (B) (C) (D) l5-Methylprostaglandin F2alpha(Hemabate) Sildenafil (Revatio, Viagra) Nitric oxide Epoprostenol (Flolan) 23. One of the factors that determines the blood level of local anesthetic agent following regional anesthesia is the site of injection. In order of decreasing serum local anesthetic concentration after placement of a regional block, which of the following is the MOST accurate sequence? (A) (B) (C) (D) 24. Which of the following local anesthetics is combined with lidocaine to produce the eutectic mixture of local anesthetics (EMLA) cream? (A) (B) (C) (D) 25. Dobutamine Norepinephrine Vasopressin Phenylephrine Which statement about the supraclavicular approach to the brachial plexus is MOST likely true? (A) (B) (C) (D) 27. Etidocaine Mepivacaine Bupivacaine Prilocaine Which of the following vasoactive agents is MOST likely to decrease systemic vascular resistance (SVR)? (A) (B) (C) (D) 26. Lumbar epidural, femoral nerve, intercostal Caudal epidural, intercostal, brachial plexus Intercostal, femoral nerve, caudal epidural Caudal epidural, lumbar epidural, femoral nerve The point of needle entry is medial to the clavicular head of the sternocleidomastoid. Phrenic nerve block occurs in less than 5% of cases. The block provides reliable anesthesia for shoulder surgery. Ultrasound allows visualization of the nerves to be blocked. Which of the following is MOST likely to cause the oxyhemoglobin dissociation curve to shift to the right? (A) (B) (C) (D) Decrease in pH Hypothermia Carboxyhemoglobin Decreased 2,3-diphosphoglycerate (2,3-DPG) 28. A normovoleinic patient with hyponatremia who is scheduled for surgery has the following laboratory values: Test Serum sodium (mmol/L) Serum osmolality (mOsm/kg) Urine sodium (mmol/L) Patient Data 130 265 35 Normal Values 135-145 280-300 20 Which of the following medical conditions is MOST likely associated with this patient’s laboratory values? (A) (B) (C) (D) 29. Water intoxication Hyperglycemia Diabetes insipidus Syndrome of inappropriate antidiuretic hormone secretion Which of the following ventilator settings is NOT usually set during high-frequency oscillatory ventilation (HFOV)? (A) (B) (C) (D) Inspiratory time Tidal volume Frequency Amplitude 30. In a patient with a heart rate of 120 beats/min and a mean arterial pressure of 50 mm Hg, which of the following sets of hemodynamic data is MOST consistent with cardiogenic shock induced by acute right-sided heart failure? 31. Which of the following would MOST likely indicate that a 65-year-old patient scheduled for emergency exploratory laparotomy is in septic shock? (A) (B) (C) (D) Mixed venous oxygen saturation of 70% Serum lactic acid level of 4 mg/dL Base excess of 2.1 mg/dL Mean arterial pressure of 55 mm Hg 32. Which of the following is MOST likely a part of The joint Commission “time-out” verification protocol conducted before the start of surgery? (A) (B) (C) (D) 33. According to the American Congress of Obstetricians and Gynecologists, which of the following would be the MOST appropriate first-line therapy for acute treatment of hypertension in a patient with severe preeclampsia (eg, blood pressure 190/105 mm Hg)? (A) (B) (C) (D) 34. The needle should be advanced to a deeper position. The needle should he withdrawn and redirected more superiorly. The needle should be withdrawn and redirected more inferiorly. The needle is in an optimal position A patient presents with painful paresthesias radiating to the dorsal web space between the thumb and foreļ¬nger following a midhumeral fracture. Which of the following nerves is MOST likely to have been injured by the midhumeral fracture? (A) (B) (C) (D) 36. Sublingual nifedipine Intravenous magnesium sulfate Sodium nitroprusside infusion Intravenous labetalol An axillary block is being performed for surgery on the palmar aspect of the thumb. As the needle is advanced with nerve-stimulator guidance, the patient reports paresthesias in the fifth digit, and finger flexion is seen at 0.4 volts. Which statement about the needle position is MOST likely true? (A) (B) (C) (D) 35. Surgical site Administration of beta-blockers Use of a warming device Appropriate selection of antibiotics Radial nerve Musculocutaneous nerve Ulnar nerve Median nerve A woman presents with refractory pain from advanced but localized anal cancer despite optimized systemic opioid therapy and adjuvant medications. She reports burning pain in her anus radiating to her vagina, and pain to the touch upon wiping after voiding. Neurolytic block of which of the following would provide the MOST appropriate management of her pain? (A) (B) (C) (D) Celiac ganglion Superior hypogastric plexus Left lumbar sympathetic ganglion Pudendal nerves 37. A 4-year-old child scheduled for a 4-hour ear reconstruction has been intubated with an uncuffed tracheal tube. With the tube correctly positioned in the trachea, a stethoscope is placed over the larynx and auscultation is performed while positive pressure applied to the tracheal tube is gradually increased. Under which of the following conditions is extubation and reintubation with a different tracheal tube LEAST likely to be warranted? (A) (B) (C) (D) 38. Which of the following is MOST likely to be associated with an increased risk of postdural puncture headache (PDPH) in an adult? (A) (B) (C) (D) 39. Trigeminal neuralgia Complex regional pain syndrome type II Multiple sclerosis Pancreatitis You have been called to evaluate a patient with oliguria on postoperative day l. Which of the following findings is MOST consistent with an intrarenal etiology for oliguria? (A) (B) (C) (D) 41. Patient age of 20 years Increased body mass index Increased opening pressure at time of lumbar dural puncture History of migraine headaches The pain associated with which of the following is MOST likely to be classified as nociceptive pain? (A) (B) (C) (D) 40. Leak initially heard at 10 cm H2O Leak initially heard at 20 cm H2O Leak initially heard at 35 cm H2O No leak heard at 50 cm H2O Urine specific gravity greater than 1.020 Fractional excretion of sodium (FENa) less than 1% Urine osmolality greater than 1,000 mOsm/kg Urine sodium greater than 40 mEq/L. A 5-year-old boy is undergoing an orchiopexy. Assuming a normal body mass index, which of the following is the MOST appropriate rate for maintenance intravenous fluid administration? (A) (B) (C) (D) 10 mL/h 30 mL/h 60 mL/h 100 ml/h 42. You have been providing anesthesia for an emergent caesarean delivery. The neonate has just been delivered, and a colleague is now available to care for the mother. Despite opening the airway and providing tactile stimulation and positive pressure ventilation the neonate is apneic and has a heart rate of 50 beats/min. According to the 2010 American Heart Association (AHA) Neonatal Resuscitation guidelines, which of the following interventions is MOST appropriate at this time? (A) (B) (C) (D) 43. Which of the following is MOST likely associated with the administration of succinylcholine to an otherwise healthy patient with a dibucaine number of 20? (A) (B) (C) (D) 44. Prolonged onset of action Increased dose requirements Severe hyperkaleinia Prolonged duration of action Which statement about physiologic anemia of infancy is MOST likely true? (A) (B) (C) (D) 45. Administration of epinephrine Administration of atropine Administration of vasopressin Initiation of chest compressions A healthy term neonate reaches the lowest hemoglobin at 8-12 weeks of postnatal age (48-52 weeks postconceptual age). A hemoglobin of 6 g/dL would be considered normal for a term neonate at the nadir of physiologic anemia. In premature neonates, the hemoglobin concentration at the nadir is inversely proportional to gestational age at birth. Red blood cell transfusion of a premature neonate results in a higher hemoglobin value at the nadir of physiologic anemia. Which of the following drugs is the BEST choice for lowering intracranial pressure (ICP) while preserving cerebral perfusion pressure (CPP) in a patient with intact cerebral autoregulation? (A) (B) (C) (D) Propofol Thiopental Mannitol Sevoflurane 46. An unconscious patient with a systolic blood pressure of 60 mm Hg is brought into your hospital for an emergent craniotomy secondary to intracranial hemorrhage after a snowmobile accident. Which of the following would be BEST to use during laryngoscopy? (A) (B) (C) (D) 47. A patient with end-stage liver disease secondary to alcoholic cirrhosis requires general anesthesia for repair of a fractured hip. Which of the following anesthetic interventions is MOST likely to preserve hepatic blood flow? (A) (B) (C) (D) 48. Manual in-line neck stabilization Hard cervical collar Soft cervical collar In-line cervical traction Application of positive end-expiratory pressure (PEEP) Administration of isoflurane Spinal anesthesia Use of sodium thiopental for induction Arterial blood gas analysis on a patient in the intensive care unit receiving 2 L/min of oxygen by nasal cannula demonstrates the following: PaO2 PaCO2 pH HCO3- 104 mm Hg 38 mm Hg 7.42 24 mEq/L Which of the following is the BEST interpretation of this blood gas? (A) (B) (C) (D) 49. Respiratory acidosis Metabolic acidosis Respiratory alkalosis Normal Which of the following variables is MOST likely calculated (rather than measured) in a standard blood gas analyzer? (A) (B) (C) (D) PO2 pH PCO2 [HCO3-] 50. Which of the following conditions is MOST likely indicated by the presence of an isolated tall v wave on the central venous pressure (CVP) waveform? (A) (B) (C) (D) 51. A 58-year-old woman is admitted to the intensive care unit after open repair of a type-III thoracoabdominal aortic aneurysm. Preoperatively, an intrathecal catheter was placed for cerebrospinal fluid drainage. Estimated blood loss was 6 L, and packed red blood cells, cell saver blood, platelets, fresh frozen plasma, and cryoprecipitate were administered to treat anemia and coagulopathy. Postoperatively, the patient is unable to move her lower extremities. Sensation is normal. She has no back pain. Which of the following is MOST likely to account for her neurologic deficit? (A) (B) (C) (D) 52. Mitral stenosis Tricuspid regurgitation Constrictive pericarditis Tricuspid stenosis Epidural hematoma Brown-Séquard syndrome Anterior spinal artery syndrome Guillain-Barré syndrome A 55-year-old man with a history of cocaine abuse presents to the operating room with a Stanford type A aortic dissection. He is awake, alert, and complaining of chest pain. His blood pressure is 75/40 mm Hg, pulse l05 beats/min, SaO2 95% on 2 L nasal cannula. A 12-lead electrocardiogram reveals ST elevation in leads II, III, and aVF. An echocardiogram reveals large pericardial fluid with right ventricular compression during systole. Which of the following is the BEST initial management strategy for this patient? (A) (B) (C) (D) Pericardiocentesis Surgical repair Coronary angiography Toxicology screen 53. A 26-year-old woman at 39 weeks gestation acutely complains of shortness of breath while pushing during the second stage of labor. Pulse oximetry indicates an oxygen saturation of 65%. The patient becomes unresponsive and has a weak but palpable pulse. She is intubated and emergently taken to the operating room for cesarean delivery. After delivery of the infant, the parturient’s blood pressure is 62/38 mm Hg and oxygen saturation is 70%. Transesophageal echocardiography shows evidence of pulmonary artery hypertension and decreased right ventricular function. The obstetrician reports the uterus is firm but that severe vaginal bleeding and bleeding within the surgical field persists. Management of this patient’s hemorrhage should MOST likely include administration of (A) (B) (C) (D) prostaglandin F2alpha (Hemabate). cryoprecipitate. intramuscular methylergonovine maleate (Methergine). heparin infusion. 54. Which of the following umbilical artery blood gas values is MOST likely to be associated with an increased risk of neonatal complications? 55. A 65-year-old man complains of painless visual loss in his right eye 2 days after a coronary artery bypass procedure. Preoperative carotid ultrasound revealed no significant atherosclerosis. Funduscopic examination reveals optic disk swelling. Which of the following is the MOST likely diagnosis? (A) (B) (C) (D) 56. Cortical blindness Anterior ischemic optic neuropathy Temporal arteritis Posterior ischemic optic neuropathy A fiberoptic bronchoscope is inserted into a properly placed left-sided double-lumen tube. Each of the following may be visualized EXCEPT (A) (B) (C) (D) 3 orifices of the right upper lobe bronchus via the tracheal lumen. longitudinal elastic bundles extending posteriorly via the bronchial lumen left upper and lower lobe bronchi via the bronchial lumen. proximal left upper lobe bronchus via the tracheal lumen. 57. Anesthesia is being induced in a 3-year-old child with congenital heart disease using an inhalation technique. Which of the following congenital heart lesions is MOST likely to slow the rate of induction of anesthesia? (A) (B) (C) (D) 58. Which of the following is MOST likely to increase as adults age? (A) (B) (C) (D) 59. Proximal limb weakness Preservation of autonomic function Decreased muscle strength with activity Resistance to depolarizing blockers A 28-yearold woman at 39 weeks gestation presents for cesarean delivery due to breech presentation. She has a history of hypertrophic cardiomyopathy (HCM). Her only medication is metoprolol. She reports having a few presyncopal episodes before her pregnancy. Which statement about the anesthetic management of this patient is MOST likely true? (A) (B) (C) (D) 61. Closing capacity Total lung capacity Diffusion capacity Vital capacity A 56-year-old man presents for resection of a bronchial mass. He has been diagnosed with Lambert-Eaton myasthenic syndrome (LEMS). Which of the following is MOST likely to be present? (A) (B) (C) (D) 60. Ventricular septal defect Tricuspid atresia Patent ductus arteriosus Aortic coarctation Metoprolol should be discontinued before surgery. Phenylephrine is the preferred drug for treatment of hypotension. Single-injection spinal anesthesia is a preferred anesthetic technique. If general anesthesia is required, propofol is the preferred agent for induction of anesthesia. Which of the following is MOST likely to be a perioperative consideration for a 4-yearold with a history of Prader-Willi syndrome (PWS)? (A) (B) (C) (D) Postoperative monitoring for obstructive sleep apnea An increased requirement for pain medications Need to administer perioperative stress-dose steroids A resistance to nondepolarizing neuromuscular blocking drugs 62. A popliteal block is performed as the primary anesthetic for repair of an Achilles tendon rupture. During the surgery the patient begins to complain of pain along the medial aspect of his ankle. Which of the following nerves is MOST likely to be inadequately blocked? (A) (B) (C) (D) 63. Deep peroneal nerve Sural nerve Superficial peroneal nerve Saphenous nerve Major thromboelastogram parameters are shown below Which of the following interpretations of these parameters is MOST accurate? (A) (B) (C) (D) 64. After receiving an uneventful 45-mg, 5% hyperbaric lidocaine spinal anesthetic for an outpatient hysteroscopy, a patient calls on postoperative day l to complain of severe burning in her buttocks and posterior thighs. Which statement about this patient’s condition is MOST likely true? (A) (B) (C) (D) 65. R-time reflects platelet function. LY30 reflects fibrinogen formation. MA reflects clot strength. K-time reflects fibrinolysis activity. This is a dose-dependent phenomenon. The patient should be treated with nonsteroidal antiinflammatory agents. A neurologic consult should be obtained for suspected cauda equina syndrome. Use of a lower concentration of lidocaine would have reduced the risk. Epidural administration of 3% 2-chloroprocaine results in a rapid onset of neural blockade. Which of the following properties is MOST likely responsible for this drug’s rapid onset? (A) (B) (C) (D) Lipid solubility Degree of protein binding Drug concentration The pKa of the drug 66. A patient develops acute respiratory distress syndrome following aspiration of gastric contents during induction of anesthesia. Which of the following is MOST likely to be associated with a decreased risk of mortality for this patient? (A) (B) (C) (D) 67. Which of the following agents would be MOST likely to increase cardiac output and reduce pulmonary vascular resistance in a patient with end-stage heart disease? (A) (B) (C) (D) 68. Gamma-aminobutyric acid-A (GABAA) receptor agonism Gamma- aminobutyric acid-B (GABAB) receptor agonism GABAA receptor antagonism Alpha2 receptor agonism A 47-year-old man developed pain along the C6 dermatome. There is no history of injury. On physical examination, there are no sensorimotor disturbances or skin changes in the upper extremities. Which of the following BEST describes this type of pain? (A) (B) (C) (D) 70. Milrinone Epinephrine Norepinephrine Dopamine Which of the following is the MOST likely mechanism of action of baclofen? (A) (B) (C) (D) 69. Increasing FIO2, to maintain arterial oxygen saturation above 94% Increasing positive end-expiratory pressure (PEEP) to maintain a PaO2/FIO2 ratio of at least 300 Limiting plateau pressure to less than 30 cm H2O Setting tidal volume to 10 mL/kg (predicted body weight) Allodynia Complex regional pain syndrome Hyperalgesia Neuralgia Which of the following symptoms is MOST consistent with the diagnosis of severe lumbar spinal stenosis? (A) (B) (C) (D) Pain that worsens when bending forward Numbness and tingling in the toes that worsen when walking uphill Burning pain in the calves that worsens when riding a bicycle Burning pain in the thighs that worsens when walking downhill 71. A woman taking fluoxetine (Prozac) for depression does not mention this to her treating physician because she is embarrassed. Four days after being given amitriptyline for postherpetic neuralgia, she develops palpitations and is taken to the emergency department. There she is found to have a QRS complex duration greater than I60 ms and intermittent episodes of ventricular tachycardia without loss of consciousness. Which of the following is the MOST appropriate immediate therapy for her dysrhythmia? (A) (B) (C) (D) 72. Which statement about a DVIR pacemaker is MOST likely true? (A) (B) (C) (D) 73. The atrium and ventricle are sensed. The paced rate may respond to increases in minute ventilation. The paced rate is not inhibited by the patient's intrinsic heart rate. Only the ventricle is paced. A patient with known hereditary angioneurotic edema (HAE) is scheduled for an elective laparoscopic cholecystectomy. Which of the following is LEAST likely to be indicated in the preoperative prophylaxis against complications of HAE? (A) (B) (C) (D) 74. Amiodarone Calcium gluconate Sodium bicarbonate Procainamide Daily administration of an anabolic steroid (eg, danazol) beginning 5 days before surgery Single close of epsilon-aminocaproic acid on the morning of surgery Administration of fresh frozen plasma to achieve a minimum C1 esterase inhibitor level of approximately 40% normal Administration of Berinert P (C1 esterase inhibitor concentrate) on the morning or surgery An increase in which of the following is MOST likely to result in an increase in myocardial wall tension? (A) (B) (C) (D) Ventricular wall thickness Ventricular cavity size Ejection fraction Systemic venous capacitance 75. A healthy woman resents at 33 weeks gestation in preterm labor. She has a cervical dilation of 4 cm. The obstetrician plans to attempt tocolysis but also requests that epidural analgesia be provided since the patient is complaining of moderate pain. If the patient remains normotensive, which of the following will MOST likely decrease uteroplacental blood flow? (A) (B) (C) (D) 76. Compared to boys receiving postoperative caudal analgesia following circumcision, which statement about other postoperative analgesic options is MOST likely true? (A) (B) (C) (D) 77. Epidural analgesia with 0.0625% bupivacaine plus 1:200,000 epinephrine Magnesium sulfate Nifedipine Uterine contractions Boys receiving parenteral analgesia are significantly more likely to require rescue medication. Boys receiving a dorsal nerve penile block are significantly more likely to require rescue medication. Boys receiving parenteral analgesia are significantly more likely to develop postoperative nausea or vomiting. Boys receiving a dorsal nerve penile block are significantly less likely to develop motor nerve weakness. An obese man complains of pain in the right lower back and buttock radiating to the right lateral thigh and right groin but not extending below the knee. Examination reveals sensory deficits on the skin of the right lateral thigh and right upper buttock with a loss of muscle bulk in the right thigh. External rotation of the hip is not painful. Which statement about this patient is MOST likely true? (A) (B) (C) (D) Nonsteroidal antiinflammatory drugs (NSAIDs) are contraindicated in this condition. A transforaminal injection of steroid along the ipsilateral L4 nerve root may be helpful. Steroid injection at the site of the anterior superior iliac spine is likely to result in significant relief. An epidural steroid injection maybe helpful in relieving symptoms. DIRECTIONS FOR ITEMS 78 AND 79: These Items refer to the diagnosis, treatment, or management of a single patient. 78. One month following her surgery to repair a fracture of the styloid process of the distal ulna, a woman complains of pain and numbness on the dorsal surface of the hand radiating from the medial wrist to the 4th and 5th finger. She reports intermittent sweating of the hand but denies any swelling, change of skin color, or nail texture. Which of the following statements is MOST likely true? (A) (B) (C) (D) 79. The patient has an ulnar neuralgia. The patient has complex regional pain syndrome 1 (formerly known as reflex sympathetic dystrophy). The patient has complex regional pain syndrome II (formerly known as causalgia). The patient has an injury to the superficial branch of the radial nerve. Several weeks later while being: treated with oral sustained-release morphine, 30 mg three times daily, and gabapentin, l,200 mg three times daily, the woman is observed to have a new tremor in the affected hand. She reports that she is having trouble coordinating movements with that hand during activities such as buttoning her blouse. Her tremor and incoordination are MOST likely due to which of the following? (A) (B) (C) (D) Emotional distress Involvement of a motor branch of the ulnar nerve at the time of her injury Evolution of complex regional pain syndrome (CRPS) II Her pharmacologic regimen DIRECTIONS FOR ITEMS 80 AND 81: These Items refer to the diagnosis, treatment, or management of a single patient. 80. A 75-year-old woman with Parkinson disease is seen in the preoperative clinic prior to hysterectomy. Which of the following signs is MOST likely associated with Parkinson disease? (A) (B) (C) (D) 81. Lack of tone Intention tremor Hemiballismus Bradykinesia Which of the following antiemetic medications is MQST suitable for management of postoperative nausea and vomiting in this patient? (A) (B) (C) (D) Ondansetron Droperidol Metoclopramide Prochlorperazine DIRECTIONS FOR ITEMS 82 AND 83: These items refer to the diagnosis, treatment, or management of a single patlent. 82. Which of the following is MOST likely increased in a healthy parturient at term? (A) (B) (C) (D) 83. Systemic vascular resistance Central venous pressure Hematocrit Cardiac output Compared to nonpregnant patients, which statement about a parturients pulmonary status is MOST likely true? (A) (B) (C) (D) Tidal volume remains unchanged. Viral capacity increases. Closing capacity remains unchanged. Total lung capacity increases. DIRECTIONS FOR ITEMS 84 AND 85: These items refer to the diagnosis, treatment, or management of a single patient. 84. A 67-uyear-old patient with no prior history of cardiac disease is scheduled to undergo a Whipple procedure. Prior to induction of anesthesia the patient is in sinus rhythm with a heart rate of 81 beats per minute (bpm) and a blood pressure of 137/88 mm Hg. During the procedure the following is noted on the monitor. According to current Advanced Cardiac Life Support (ACLS) guidelines, which of the following is the MOST appropriate initial management? (A) (B) (C) (D) Synchronized cardioversion Intravenous lidocaine Intravenous amiodarone Intravenous magnesium 85. Despite the initial therapy the rhythm deteriorates further and, as shown on the monitor tracing below, the patient becomes pulseless. According to current Advanced Cardiac Life Support According to current Advanced Cardiac Life Support (ACLs) guidelines, which of the following is the MOST appropriate management at this time? (A) (B) (C) (D) Provide a single defibrillation shock. Provide 3 consecutive (“stacked”) defibrillation shocks. Administer intravenous epinephrine. Administer intravenous vasopressin. DIRECTIONS FOR ITEMS 86 THROUGH 88: These items refer to the diagnosis, treatment, or management of a single patient. 86. You are asked to examine a random sample of 1,000 patient charts to study whether use of paravertebral blocks prevents chronic postoperative pain after elective hernia surgery. Among the 600 patients who did not receive paravertebral blocks, 500 did not have pain. Of the 400 patients who had paravertebral blocks, 300 did not have pain. Among those who had a paravertebral block, which of the following BEST represents the odds of having pain? (A) (B) (C) (D) 87. A study involving l,000 patients assessed the efficacy of paravertebral blocks in preventing chronic pain after elective hernia surgery. Of the 400 patients who had paravertebral blocks, 300 did not have pain. Among the 600 patients who did not receive paravertebral blocks, 500 did not have pain. Which of the following BEST expresses the odds ratio describing the relationship of pain to paravertebral block exposure? (A) (B) (C) (D) 88. 0.33 0.25 3 0.2 1.65 0.61 0.33 0.2 A study involving 1,000 patients assessed the efficacy of paravertebral blocks in preventing chronic pain after elective hernia surgery. Of the 400 patients who had paravertebral blocks, 300 did not have pain. Among the 600 patients who did not receive paravertebral blocks, 500 did not have pain. The calculation MOST likely to determine if the use of paravertebral blocks is associated with a statistically significant change (P<.05) in the odds of chronic pain is (A) (B) (C) (D) a chi-square test. an odds ratio. a log-rank test. a relative risk. DIRECTIONS FOR ITEMS 89 AND 90: These items refer to the diagnosis, treatment, or management of a single patient. 89. Shortly after arrival in the emergency department a previously healthy 20-year-old athlete with an isolated closed head injury develops profound hypoxemia associated with bilateral infiltrates on his chest radiograph. Which of the following is MOST likely to be decreased in this patient? (A) (B) (C) (D) 90. Left ventricular output Pulmonary artery pressure Systemic vascular resistance Pulmonary artery occlusion pressure Following tracheal intubation and initiation of positive pressure ventilation with supplemental oxygen, the patient remains hypertensive and tachycardic. Which of the following interventions is the MOST appropriate? (A) (B) (C) (D) Furosemide Mannitol Permissive hypercapnia Esmolol DIRECTIONS FOR ITEMS 91 AND 92: These items refer to the diagnosis, treatment, or management of a single patient. 91. A 46-year-old woman presents to the preoperative anesthesia clinic in preparation for next-day elective plastic surgery. She is currently asymptomatic but does report that she has frequent episodes of facial flushing and diarrhea with the most recent episode occurring last evening. She was diagnosed with asthma 2 years ago when her other symptoms also began. She reports that she often develops an asthma attack at the same time as the flushing and diarrhea. Which statement about the preoperative evaluation of this patient is MUST likely true? (A) (B) (C) (D) 92. Surgery can proceed without any further evaluation. Spirometry should be performed. Urinary metanephrine levels can establish the likely diagnosis. An echocardiogram should be obtained. After a thorough evaluation, the patient is diagnosed with a duodenal carcinoid tumor. An echocardiogram is normal. The patient is scheduled to undergo excision of the tumor. Which statement about the perioperative management of this patient is MUST likely true? (A) (B) (C) (D) She should receive octreotide preoperatively. A rapid sequence induction with succinylcholine is recommended. Propofol is contraindicated. Ondansetron should be avoided. DIRECTIONS FOR ITEMS 93 AND 94: These items refer to the diagnosis, treatment, or management of a single patient. 93. An elderly man with urosepsis develops agitation associated with delirium while in the intensive care unit. Which of the following would be LEAST likely to be associated with a diagnosis of delirium? (A) (B) (C) (D) 94. Fluctuating level of consciousness Focal neurologic findings Reduced awareness of environment Inability to maintain attention or focus In the absence of significant physiologic derangements (eg, hypoxemia, hypoglycemia), which of the following therapies would be MOST effective in treating delirium in this patient? (A) (B) (C) (D) Fluoxetine Haloperidol Lorazepam Fentanyl DIRECTIONS FOR ITEMS 95 AND 96: These items refer to the diagnosis, treatment, or management of a single patient. 95. A 59-year-old patient complains of pain over her face extending from her cheek to temple and scalp without a history of an associated rash. The pain is sharp and stabbing in nature. Which of the following would provide the MOST appropriate initial therapy? (A) (B) (C) (D) 96. Naproxen Morphine Acyclovir Carbamazepine Unfortunately, the patient’s pain is unresponsive to a number of medication trials. Magnetic resonance imaging of the brain reveals no evidence of a neurologic tumor. Which of the following would be the MOST appropriate next therapy? (A) (B) (C) (D) Radiofrequency thermal lesioning of the maxillary (V2) nerve Application of transcutaneous electrical nerve stimulation (TENS) Glycerol gasserian ganglion block Local anesthetic gasserian ganglion block DIRECTIONS FOR ITEMS 97 AND 98: These items refer to the diagnosis, treatment, or management of a single patient. 97. A 62-year-old man is scheduled for coronary artery bypass procedure with cardiopulmonary bypass. For which of the following concomitant valvular conditions in this patient is retrograde cardioplegia MOST likely essential? (A) (B) (C) (D) 98. Tricuspid stenosis Aortic insufficiency Mitral stenosis Mitral insufficiency During cardiopulmonary bypass, the retrograde cardioplegia delivery system is monitored via a pressure transducer. During retrograde cardioplegia, pressure measured from the cardioplegia cannula is l mm Hg. Which of the following is the MOST likely position of the retrograde cardioplegia cannula tip in this scenario? (A) (B) (C) (D) Right ventricle Coronary sinus Aortic root Left atrium DIRECTIONS FOR ITEMS 99 AND 100: These items refer to the diagnosis, treatment, or management of a single patient. 99. A patient with a history of previous low transverse cesarean delivery presents to the labor floor. According to the most recent American College of Obstetricians and Gynecologists guidelines, which of the following statements about a trial of labor after cesarean delivery (TOLAC) is MOST accurate? (A) (B) (C) (D) 100. Spontaneous labor increases the likelihood of a successful TOLAC. A history of 2 previous cesarean deliveries would be an absolute contraindication to TOLAC. Epidural analgesia is considered a risk factor for unsuccessful TOLAC. The presence of twin gestations would be a contraindication to TOLAC. The patient, whose 1 previous low transverse cesarean delivery was for a breech presentation, is requesting epidural analgesia For labor and plans to attempt a trial of labor after cesarean delivery (TOLAC). Which statement about the risk to a patient of undergoing TOLAC compared to an elective repeat cesarean delivery (ERCD) is MUST likely true? (A) (B) (C) (D) The overall risk of maternal death is less. The overall risk of a peripartum hysterectomy is higher. The risk of transfusion is significantly higher. Overall hospital stay is likely to be longer.