Clinical characteristics Biological perspective – Genetic – Neurochemical Psychological perspective – Cognitive www.psychlotron.org.uk Mood Disorders Psychological symptoms: – Persistent low mood – Diminished pleasure in normal activities – Feelings of guilt or worthlessness – Suicidal ideation Physical symptoms: – Fatigue/loss of energy – Changes in weight/appetite – Insomnia or hypersomnia www.psychlotron.org.uk Depression Psychological symptoms – Inflated self-esteem/grandiosity – Flight or ideas/racing thoughts – Extreme distractibility – Increased goal-directed behaviour – High risk hedonistic behaviour Physical symptoms – Psychomotor agitation – Decreased need for sleep www.psychlotron.org.uk Mania Unipolar (depression) – Major depressive disorder (Endogenous or reactive) – Disthymic disorder – Psychotic depression Bipolar (alternating depression and mania) – Major bipolar disorder – Cyclothymia www.psychlotron.org.uk Mood Disorder Types Unipolar – Lifetime prevalence of 5-9% in population – About 2x more likely in women – Increased rates in adolescence, old age Bipolar – Lifetime prevalence of about 1% in population (possible underestimate) – MBD more slightly common in men, cyclothymia slightly more common in women NIMH data for US population www.psychlotron.org.uk Prevalence