MEDICAL TECHNOLOGIES IN THE GREATER MONTREAL AREA : A BUOYANT SECTOR OF ACTIVITY November 2013 TABLE OF SECTOR | MEDICAL TECHNOLOGIES 2 CONTENT EXECUTIVE SUMMARY 3 REASONS TO INVEST IN GREATER MONTREAL 4 An ideal location to conquer the North-American market 5 Montreal, a hub in biomedical research and healthcare-related technologies 6 At the junction of IT and life sciences 8 Industry leaders, news and recent announcements 10 Skilled manpower from a diversified academic environment An environment conducive to innovation Incubators, business coaching and counselling 16 University based technology transfer organisations 17 The Quebec National Policy on Research and Innovation (PNRI) 18 A hot spot of open innovation and collaborative research 19 Metropolitan Montreal, a leading Venture Capital center in Canada 20 Competitive financial incentives 21 MONTRÉAL INTERNATIONAL : A PERSONAL TOUCH 24 EXECUTIVE SECTOR | MEDICAL TECHNOLOGIES 3 SUMMARY Perfect timing for Metropolitan Montreal : • Up to date medical technologies are needed to improve the quality of healthcare while reducing costs and increasing accessibility in the context of aging population • The biomedical technology sector is maturing as multinational corporations settle in Montreal following the acquisition of innovative platforms: Medtronic-Cryocath, ZimmerCAS, Elekta, Masimo • Large investments are currently taking place in three new university hospital complexes • The healthcare systems of Quebec and of Canada are transiting towards informatics and large scale data management; the electronic patient record is being implemented A long tradition of excellence in biomedical research and in the execution of clinical trials • The Montreal cluster combines research institutes, public and private laboratories, suppliers, CROs, service providers and innovative companies, all working in close interaction A dense network of colleges and universities, including two faculties of medicine, four schools of engineering and numerous research centers renown internationally Strong support by the Quebec Government to innovation and innovative companies • Implementation of the National Policy on Research and Innovation (PNRI) ( 3,7 G$) along seven strategic areas including: life science and personalized medicine • Funds for open innovation and projects carried out by research consortia • Highly competitive financial incentives 4 REASONS TO INVEST IN THE GREATER MONTREAL REGION THE GREATER MONTREAL AREA: SECTOR | MEDICAL TECHNOLOGIES 5 AN IDEAL SITE TO CONQUER THE NORTH AMERICAN MARKET Direct access to the market of the North American Free Trade Agreement (NAFTA), representing approximately ● 460 million consumers ● A total GDP of USD 17 trillion A strategic location in North America • Flying time less than 2 hours from Toronto, Boston and New York • 70 km from the U.S. border High quality transportation infrastructure Signing of the free trade agreement between • Two international airports (Montreal-Trudeau Canada and the European Union and Montreal-Mirabel) ● Better harmonization of the regulatory • One sea port amongst the busiest ports in process North America, open all year round and linked ● Increased commercial trade to more than 100 countries Economic engine of Quebec, representing 50% of the population, GDP and employment in the province ● Population : nearly 4 M ● Real GDP (in 2012) : 161 G ($ of 2007) ● Employment : nearly 2 M Source : The Conference Board of Canada, 2013 • A major logistic hub linking port-rail-road-air THE GREATER MONTREAL AREA: SECTOR | MEDICAL TECHNOLOGIES 6 A HUB IN BIOMEDICAL RESEARCH AND HEALTHCARE-RELATED TECHNOLOGIES LONG TRADITION OF EXCELLENCE EXPERTISE IN ENABLING IN BIOMEDICAL RESEARCH TECHNOLOGIES ● ● Computer graphics and 3D animation ● Medical imaging Cluster made up of world-class universities, research centers and university hospitals ● Internationally renown center for conducting clinical research ● Information technology ● Comprehensive research activities in: ● Data management ● Hosting servers and data warehousing ● Systems engineering ● Nanotechnologies & advanced materials Cardiology Neuroscience Oncology Geriatrics Metabolic diseases & nutritional disorders Genetic diseases & genomics Biomedical engineering A HUB IN BIOMEDICAL RESEARCH AND HEALTHCARE SCIENCE SECTOR | MEDICAL TECHNOLOGIES 7 RESEARCH CENTERS AND INSTITUTES RESEARCH CENTERS LINKED TO HOSPITALS ● Centre de recherche Fernand-Seguin (Institut universitaire en santé mentale de Montréal) ● Centre hospitalier de l'Université de Montréal (CHUM) ● McGill University Health Center (MUHC) ● CHU Sainte-Justine (pædiatric hospital) ● Jewish General Hospital (Lady Davis Institute) ● Hôpital Maisonneuve-Rosemont ● RESEARCH INSTITUTES ● Centre for interdisciplinary research in Rehabilitation of Greater Montreal (CRIR) ● Montreal Cardiology Institute ● Institut de réadaptation Gingras-Lindsay-deMontréal (IRGLM) ● Institut de recherches cliniques de Montréal (IRCM) ● Douglas Mental Health University Institute ● Institut de recherche Robert Sauvé en santé et en sécurité du travail du Québec (IRSST) Montreal Children Hospital ● Institut du cancer de Montréal (ICM) ● Hôpital du Sacré-Cœur ● Montreal Chest Institute ● Montreal Neurological Institute and Hospital ● Institut universitaire de gériatrie de Montréal ● Institut Philippe-Pinel de Montréal Source : Montreal InVivo Interactive Map http://www.montreal-invivo.com/web/la-grappe/cartographie/ THE GREATER MONTREAL AREA: SECTOR | MEDICAL TECHNOLOGIES 8 AT THE JUNCTION OF IT AND LIFE SCIENCES LIFE SCIENCES AND HEALTH TECHNOLOGIES (LSHT) INFORMATION AND COMMUNICATION TECHNOLOGIES (ICT) ● 45,000 employments in 600 establishments ● ● With more than 12,000 researchers and professionals More than 92,000 skilled employees in nearly 5,000 organizations3 ● 400 subsidiaries of foreign corporations4 ● 12 500 positions in R-D activities5 : ● In 300 public agencies and government-own organisations1 ● 235 companies including 80 subsidiaries of foreign corporations2 7 500 researchers in centers own by private corporations 5 000 researchers in more than 100 university research centers 1 : Statistics Canada 2012 and Expertise recherche Québec 2012 2 : http://www.montrealinternational.com/sciences-de-la-vie/ 3 : Statistics Canada 2012 4 : http://www.montrealinternational.com/technologies-de-linformation-et-des-communications/ 5 : http://www.montrealinternational.com/innovation-technologies-de-linformation-et-des-communications/ THE GREATER MONTREAL AREA: SECTOR | MEDICAL TECHNOLOGIES 9 MULTIPLE BRIDGES BETWEEN SECTORS OF THE ECONOMY CROSS-FERTILISATION ● ICT (Information and Communication Technologies) Telemedecine and e-health ● Video games industry virtual reality, training platforms, improving patient’s experience ● Aeronautics simulators, high precision machining and manufacturing ● Genomics & bio-informatics diagnostics, personalized medicine ● Logistics inventory management, optimization of logistic chains, traceability MONTREAL, «VILLE UNESCO DU DESIGN» ● A node of the UNESCO cities of design network (2006) – web site ● Unique creativity centre (scenic arts, media arts and technology, industrial design) ● Contribution of design and creativity to the medical technology sector : Ergonomy, 3D simulation, motion tracking and ambient monitoring Improving «patient’s experience», enriched health and life spaces A HUB IN BIOMEDICAL RESEARCH AND MEDICAL TECHNOLOGY SECTOR | MEDICAL TECHNOLOGIES 10 INDUSTRY LEADERS, NEWS AND ANNOUNCEMENTS Kinova Loan from Invest Québec to support the company’s effort in commercializing its Jaco platform on the U.S. and European markets. The JACO arm, for which the company holds several patents, is the first three-fingered robotic arm designed to increase the functional independence of motorized wheelchair users (October 2013). Carré Technologies Official launching of the intelligent shirt Hexoskin, a high tech garment with integrated sensors that captures body metrics including heart rate and pulse recovery, breathing rate and acceleration. Hexoskin offers an easy and more natural way of regularly capturing precise physiological data (August 2013). Emovi Emovi has signed a distribution agreement for the commercialisation overseas of KneeKG, a unique system used for precisely measuring and documenting the knee joint function in an outpatient setting. The KneeKG provides objective data regarding the function of the knee and highlights deficiencies in gait associated with knee problems (September 2013). EMcision International The company specializing in advanced radiofrequency-based medical devices used in surgery, has announced that it has sold its first units of the Habib™ RF DUO 13 catheter - a new device with immense potential to help abdominal cancer patients (August 2013). Sources : Flash InVivo http://www.montreal-invivo.com/web/ and corporate internet sites A HUB IN BIOMEDICAL RESEARCH AND MEDICAL TECHNOLOGY SECTOR | MEDICAL TECHNOLOGIES 11 INDUSTRY LEADERS, NEWS AND ANNOUNCEMENTS (CONT’D) Medtronic In 2012, the company announced an investment of 50 M$ in its Medtronic Cryocath division, more specifically into its R&D Centre, in advanced training resources and in its manufacturing unit. This follows the acquisition by the American multinational of the cryotherapy platform developed in Montreal to treat different heart conditions such as cardiac arryhtmias. Hoffmann-La Roche and the Montreal Cardiology Institute In April 2012, the Montreal Cardiology Institute has been designated a hub for translational medicine devoted to cardiometabolic disease in the global network of the multinational pharmaceutical company Roche. This novel approach aims at transposing results of clinical research into personalized treatments for improving patients’ cardio-vascular health. Piramal Life Sciences Following the acquisition of Biosyntech’s platform on biomaterials, the Indian-based multinational has initiated the commercialisation of BST-CarGel, a novel surgical biopolymer to be used for repairing knee cartilage. The gel, fluid at room temperature, is mixed in an OR setting with aulogous blood and inserted into the patient’s cartilage where it thickens and favours the reconstruction of damaged tissues. Elekta In 2010, the Swedish group Elekta has acquired Resonant Medical, a company that has developed a 3D echography technology to guide precisely radiotherapy equipment during cancer treatment procedures. Sources : Flash InVivo http://www.montreal-invivo.com/web/ and corporate internet sites A HUB IN BIOMEDICAL RESEARCH AND MEDICAL TECHNOLOGY SECTOR | MEDICAL TECHNOLOGIES 12 INDUSTRY LEADERS, NEWS AND ANNOUNCEMENTS (CONT’D) Héma-Québec (web site) Héma-Québec's mission is to efficiently provide adequate quantities of safe, optimal blood components, substitutes, human tissues and cord blood to meet the needs of all Quebecers. It provides products and services in the fields of transfusion medicine and human tissue transplantation. The only public cord blood bank in Canada, operated by Héma-Québec since 2004, has increased its activities at a sustained pace both nationally and internationally. Since September 2012, Héma-Québec has been offering its cord blood units to the international community through Bone Marrow Donors Worldwide (BMDW). MEDEC (web site) MEDEC is the national association created by and for the Canadian medical technology industry. Its goals are to advance health outcomes for patients in Canada as well as the growth and vibrancy of the industry in Canada while favoring access to proven, safe and innovative medical technology developed by its member companies. With an office and increasing presence in Quebec, MEDEC is the primary source for advocacy, information and education on the medical technology industry for members, the greater healthcare community, industry partners and the general public. MEDEC strongly supports the recent announcement by the Government of Canada of the successful conclusion of negotiations with the European Union of the surrounding the Comprehensive Economic and Trade Agreement (CETA) which will boost commercial ties between the two partners particularly the healthcare and medical technology sector. SKILLED MANPOWER SECTOR | MEDICAL TECHNOLOGIES 13 FROM A DIVERSIFIED ACADEMIC ENVIRONMENT A large university network ● 11 academic institutions ● More than 170 000 university students, of which 20 000 foreign students The largest pool of new university graduates in Canada 40 000 graduates per year The most multilingual population in Canada ● 50 % is bilingual ● 20 % is multilingual (three languages and more) Engineering schools: Faculty of Medicine: École Polytechnique de Montréal University of Montreal & McGill University École de Technologie Supérieure Management schools: McGill University HEC Montréal, UQAM, Concordia University Concordia & McGill Sources : Association d’études canadiennes, 2007 ; Ministère de l’Éducation, du Loisir et du Sport (MELS) du Québec, 2011 ; Statistique Canada, 2007 et 2012 SKILLED MANPOWER SECTOR | MEDICAL TECHNOLOGIES 14 TRAINING AND RESEARCH IN BIOMEDICAL ENGINEERING Biomedical Engineering Institute of U de M McGill University - Department of Biomedical Engineering • Linked with École Polytechnique and the University of Montreal • A pioneer in North America, part of McGill Faculty of Medicine Research Objectives: Research areas: ● Cardiac electrophysiology ● Biomedical signals, systems and imaging ● Biomechanics and biomaterials/ rehabilitation ● Biomedical modelling and simulation Web site Research Centre in Biomedical Science and Technologies (GRSTB) A multidisciplinary regrouping of labs, scientists and engineers from different institutions Web site ● Signals, systems and modelling ● Biomaterials and tissue engineering ● Artifical cells and drug delivery systems ● Lab-on-a-chip and biosensors ● Nanoparticles, nanomedecine ● Neuro-imaging ● Personalized medicine Web site SKILLED MANPOWER SECTOR | MEDICAL TECHNOLOGIES 15 TRAINING AND RESEARCH IN BIOMEDICAL ENGINEERING Biomedical Engineering program of École de technologie supérieure (ETS) Concordia University – Office of research Research axis: ● Sensors and bio-opto-electronics ● Biomechanics and biomaterials ● Cardio-vascular diagnostics ● Medical imaging and devices ● Design, testing and manufacturing ● Occupational health and safety ● Cellular imaging ● Telehealth, electronic patient records ● Lab-on-a-chip and microfluidics; MEMS Enabling technologies: ● Nanomaterials and drug delivery ● Software and informatics ● ● Nanotechnologies Mass spectrometry applied to biological studies biologie ● Prototyping and manufacturing ● Robotics Concordia Concordia – Centre PERFORM ● Material science ● Dedicated to new ways of researching better health through prevention ● Advanced clinical research facility available for multidiciplinary, interinstitutional studies Research themes: Web site Web site Web site AN ENVIRONMENT CONDUCIVE TO INNOVATION SECTOR | MEDICAL TECHNOLOGIES 16 INCUBATORS, BUSINESS COACHING AND COUNSELLING CTS (Campus des technologies de la santé) ● CTS provides services, physical facilities, a network of experts and programs for companies of the medical sector developing devices, instruments, systems and IT Web site CENTECH, ETS Business incubator ● Currently has about fifty active businesses ● Accepting projects of students and graduates from the early stage of the entrepreneurial process (emergence phase) Web site CQIB ● Incubator for companies in LSHT, operated in partnership with Laval Technopole ● Access to infrastructure (equipment and space), to consulting services and business networks, to funding sources Centre d’entreprises et d’innovation de Montréal (CEIM) ● CEIM offers customized management consulting and related services for the creation and development of companies Web site ● Sectors: information technology, new media, clean technology and life sciences NRC (Boucherville) ● Provides space for innovative companies ● Access to NRC expertise in photonics, microfluidics and material science Web site Web site AN ENVIRONMENT CONDUCIVE TO INNOVATION SECTOR | MEDICAL TECHNOLOGIES 17 UNIVERSITY BASED TECHNOLOGY TRANSFER ORGANISATIONS Univalor ● ● Accelerating the transfer of the results of research, conducted by researchers at the University of Montreal and its schools and most of its affiliated hospitals, to industry MSBi Valorisation (MSBiV) ● Achievements : 10 active spin-offs, $1,5 million in third party investment in spin-offs, 460 000 $ grant to spin-offs, 139 patents and 178 patent applications in progress Web site ● Provides capital, manpower and business sense to monetize promising technologies developed within: McGill University Université de Sherbrooke Bishop’s University As well as from affiliated hospitals and research centers Since 2001: Gestion Valeo 12 spin-out companies (6 in LSHT) ● To commercialize the results of research carried out by the member universities of the INRS-Université du Québec network 3,3 M$ invested in tech transfer and spin out companies Leverage factor above 50 ● In Montréal: École de technologie supérieure (ETS), l’Université du Québec à Montréal (UQAM), l’INRS-Institut-Armand Frappier Web site ● 5 spin-out companies (2 in LSHT) Web site AN ENVIRONMENT CONDUCIVE TO INNOVATION SECTOR | MEDICAL TECHNOLOGIES 18 THE QUEBEC NATIONAL POLICY ON RESEARCH AND INNOVATION (PNRI) The Government of Québec presents its new innovation policy in October 2013 The Politique nationale de la recherche et de l’innovation (PNRI) confirms the support offered by the Government of Quebec to different components of R&D and of the innovation process including continuing support to innovative companies and to the commercialisation of research A comprehensive innovation strategy while maintaining key programs A plan for investing $ 3,7 billion over 5 years Seven high priority fields of activities including the following two in LSHT: biotechnologies and personalized healthcare Continuing support to SR&ED tax credits, one of the most competitive programs in the world Incentives to innovative companies: support for first patent application, to hiring graduates in their first research jobs, to start-up companies Increased financial support to university research funds along with long term commitment Increased budget for the College Technology Transfer Centers (CCTT) CCTT in health technologies and related areas Centre de développement des composites du Québec (CDCQ): www.cdcq.qc.ca Centre de solutions technologiques en orthèses et prothèses (CSTOP): www.cstop.ca Institut international de logistique de Montréal – IILM: www.iilm.ca Vestechpro – Centre de recherche et d’innovation en habillement: www.vestechpro.com AN ENVIRONMENT CONDUCIVE TO INNOVATION SECTOR | MEDICAL TECHNOLOGIES 19 A HOT SPOT OF OPEN INNOVATION AND COLLABORATIVE RESEARCH Incentives to collaborative research (Government of Québec) Tax credits at the applicable rate1 : on 80% of eligible expenditures in connection with a research contract with a university or an eligible research center on half of the fees paid to a subcontractor at arm’s length who performed R&D on behalf of the corporation in Québec on contribution paid to a research consortium or expenditures made in connection with precompetitive research project based on a private partnership Creation and funding of formal research consortia, by sector, to promote pre-competitive research and enhance the transfer of knowledge between public labs and companies MEDTEQ - Le consortium de recherche industrielle et d’innovation en technologies médicales du Québec Web site Mission: to accelerate the development of new medical technologies for the benefit of clinicians and patients; validate their contribution to healthcare systems and their positioning on international markets Aims at facilitating networking between partners of the innovation process in med tech Targets inter-sectorial multidisciplinary projects, involving several partners (minimum of two companies and one public laboratory) Matches amounts invested by private companies up to 25% of the project costs 1 : «Taxation in Québec», Invest-Québec http://www.invest-quebec.com/documents/int/publications/FiscaliteQC2013_en.pdf GREATER MONTREAL, SECTOR | MEDICAL TECHNOLOGIES 20 A LEADING VENTURE CAPITAL CENTER IN CANADA Réseau Capital The only private equity association that brings together all stakeholders involved in the Quebec investment chain - Web site Key statistics Between 2001 and 2011, venture capital investments in Montreal-based companies of the LSHT sector exceeded 1,6 G$. The region collected near 33% of the Canadian total – the highest in Canada for this sector.1 Investments from venture capital funds are coming back in Quebec as shown by the following indicators 2 : ● In 2012, VC funds raised the highest amount of capital in 10 years (924 M$) 433 M$ were invested during the first half of 2013 in all sectors 41% of all funds available in Canada for the LSHT sector are to be found in Montreal In September 2013, BDC Venture Capital3 allocated $135 million in new capital to direct venture investments in innovative healthcare technology companies 1 : Profil_svts2013-1.pdf de www.montreal-invivo.com ; Thomson Reuters, 2012 2 : http://reseaucapital.com/nouvelles.php 3 http://www.bdc.ca/FR/solutions/capital_risque/salle_nouvelles/Pages/default.aspx#.Um6C2BBcnp4 TARGETED AND SECTOR | MEDICAL TECHNOLOGIES 21 HIGHLY COMPETITIVE INCENTIVES Tax burden on business in R&D: almost 5 times less than the average of 19 other major North American cities Cost-benefit due to R&D Tax credit Index of overall tax burden, average for R&D sectors (average of cities located in the United States = 100) Top 20 largest cities in North America, 2012 120 100 80 60 40 20 0 N.B. : Exchange rate 1 $ US = 1 $ CA Refer to Appendix 6 for methodology - Source : KPMG, 2012 TARGETED AND SECTOR | MEDICAL TECHNOLOGIES 22 HIGHLY COMPETITIVE INCENTIVES(CONT’D) Tax credit for scientific research and development 15 % allocated by the government of Canada and 17.5% by government of Quebec (the latter being refundable) Scenario ($) No1 Scientific research and experimental development (SR&ED), 2011 HYPOTHESIS1 The company is private under foreign control 20 eligible employees @ 50 000 $/year 100 % of their work is eligible Subcontractor : 200 000 $ Equipment : 150 000 $ Salary ($) FEDERAL QUEBEC 1 000 000 1 000 000 Proxy method for overhead @ 55 % 550 000 Subcontractors2 160 000 Equipments 150 000 SR&ED credit of Quebec3 Federal credit @ 20 % and Quebec credit @ 17,5 % TOTAL 100 000 -192 500 1 517 500 1 100 000 554 000 227 625 192 500 420 000 N.B. : 1 This model considers the recent changes to the tax credit for scientific research and development (2012) and therefore is valid from the 2014 fiscal year. 2 Only 80% federal and 50% in Quebec of the amount paid to the subcontractor is eligible for the credit. 3 In calculating the combined credit, the rate of provincial tax credit is applied to reduce the federal tax credit. Source : Deloitte, Tax Incentive Programs in Québec – IT, January 2011 TARGETED AND SECTOR | MEDICAL TECHNOLOGIES 23 HIGHLY COMPETITIVE INCENTIVES (CONT’D) Tax holiday for researchers and international experts Financial assistance for job creation and training Tax exemption on taxable income in Quebec for 25 % of eligible costs for implantation of training a period of five years: plans and 50 % of the costs for setting up a management service of human resources 1st - 2nd years : 100 % 3rd : 75 % th 4 : 50 % th 5 : 25 % And more… 24 MONTREAL INTERNATIONAL : CUSTOMIZED SERVICES MONTREAL INTERNATIONAL : SECTOR | MEDICAL TECHNOLOGIES 25 CUSTOMIZED SERVICES Strategic support for different projects (implementation, expansion or strategic alliances) Knowledge of financial and tax programs Assistance to expatriates in their approaches to obtain official documents Access to specialized professionals in knowledge-based sectors Assistance in the selection of investment site via a comprehensive range of key comparative data Linking with strategic actors of Greater Montreal CONTACT Ms. Ginette Audet, Ec. D. DIRECTOR, BUSINESS DEVELOPMENT INVESTMENT GREATER MONTREAL Life Sciences Office : Cellular : 514 987-9379 514 862-2978 Ginette.audet@montrealinternational.com 380, rue Saint-Antoine Ouest Bureau 8000 Montréal (Québec) H2Y 3X7 Business in Greater Montréal – Montréal International Téléphone : Télécopieur : @MontrealIntl @IntlOrgMontreal @talentmontreal 514 987-8191 514 987-1948 www.montrealinternational.com 27 APPENDICES SECTOR | MEDICAL TECHNOLOGIES ANNEXES 28 APPENDIX 1 : PRESENTATION OF MONTREAL-INVIVO - CLUSTER OF LSHT - Multinational pharmaceutical companies with Canadian headquarters in the Montreal area as AbbVie , Bristol Myers Squibb Canada , GlaxoSmithKline, Abbott Laboratories, Merck Canada , Novartis Pharmaceuticals Canada , Pfizer Canada , Sanofi and Servier Canada Business. - Greater Montréal’s health technologies industry: consisting Innovative, international-calibre companies such as Covidien, Elekta, Medtronic of Canada, TELUS Health Solutions, Zimmer CAS, etc. and a large number of locally based and highly creative SMEs such as Carré Technologies, Emovi, Kinova, etc.. - Biotechnology : number of companies with headquarters in Montreal as AlethiaBiotherapeutics , Bio- K Plus International Caprion, MethylGene, Theratechnologies, Vertex Pharmaceuticals (Canada). - Contract manufacturing research: offering a complete array of services ranging from preclinical studies to therapeutic drug monitoring in compliance with Good Manufacturing Practices (GMP); among which: Algorithme Pharma Cato Recherche Canada COREALIS Pharma Inc. Laboratoires Charles River Services Précliniques Montréal Laboratoires ITR Canada Quintiles Canada Recherche Clinique ICON (Canada) Uman Pharma. - Greater Montréal, a natural bridge between North America and Europe and an ideal location for companies looking to expand into foreign markets: In 2012, Greater Montréal’s LSHT industry exported over $820 million worth of goods. Between 2006 and 2012, the region’s LSHT exports represented $5 billion. Source :Profil_svts2013-1.pdf from www.montreal-invivo.com , with the collaboration of Montreal International SECTOR | MEDICAL TECHNOLOGIES ANNEXES 29 APPENDIX 2 : COMPANIES MEDICAL DEVICES & TECHNOLOGIES Company Web site Field of activity AMD Ritmed Dressings, OR supplies and specialty surgical products Analogic Canada Digital mammography imaging systems and flat panel detectors atms Traceability solutions for the reprocessing of medical devices and OR linens in healthcare facilities Bavaria Medical Technology Canada Catheters Baylis Medical Company Supplier of high-technology cardiology, endovascular and oncology devices bioMérieux Canada Diagnostic solutions (reagents, instruments, software) that determine the source of disease and contamination Biomod Vectorization technologies for the delivery of active ingredients via the skin Biomomentum Solutions for the biomechanical evaluation of tissues, biomaterials, and cartilage Biotonix Imaging system for postural analysis to ensure optimal spinal health and overall fitness Bracco Imaging Canada Contrast agents and solutions for medical imaging systems SECTOR | MEDICAL TECHNOLOGIES ANNEXES 30 APPENDIX 2 : COMPANIES MEDICAL DEVICES & TECHNOLOGIES (Cont’d) Company Web site Field of activity Cardinal Health Canada Distributor of medical and surgical products Carré Technologies Software and devices to monitor and record biosignals for real-time or delayed analysis Citagenix Devices and materials for bone regeneration Clemex Technologies Scientific image analysis solutions for quantitative microscopy CogniSens Devices for measuring, identifying and improving neurobiological activity ConvaTec Devices and supplies for stomacare, wound therapeutics and skin care Coroneo Medical devices for the field of cardiac surgery Covidien Distributor of medical devices and medical supplies DenPlus Designs, manufactures and distributes dental products Dymedso Introduction of new medical technologies to help those suffering from chronic respiratory diseases SECTOR | MEDICAL TECHNOLOGIES ANNEXES 31 APPENDIX 2 : COMPANIES MEDICAL DEVICES & TECHNOLOGIES (Cont’d) Company Web site Field of activity Elekta Canada Systems for image guided radiation therapy of soft tissues using latest generation, 3-D ultrasound technology EMcision Medical devices based on proven RF technology for the surgical community, endoscopists and interventional radiologists emd Technologies High-voltage advanced power electronics components targeted at the medical X-ray field Emovi System for dynamic 3D evaluation of knee motion Ergoresearch Markets “intelligent” foot orthotics and specialty orthotics as well as software for the orthopedics; runs a network of orthotics clinics Fresenius Medical Care Devices and supplies for kidney dialysis Gambro Products and therapies for kidney and liver dialysis Genia Photonics Laser based solutions and cost effective photonics for medical imaging Héma-Québec Supplies safe, optimal blood components, substitutes, human tissues and cord blood to meet the needs of Quebec population Invacare Canada Devices, equipment and products for rehab and home care SECTOR | MEDICAL TECHNOLOGIES ANNEXES 32 APPENDIX 2 : COMPANIES MEDICAL DEVICES & TECHNOLOGIES (Cont’d) Company Web site Field of activity Kinova Robotics Six-axis robotic manipulator arm with a three-fingered hand for persons with upper body mobility impairment Klox Technologies Therapeutic and cosmetic solutions based on a biophotonics system coupled with a light-trapping gel Laborie Medical Technologies Innovative medical equipment and catheters in urology and gynecology Lantheus Medical Imaging Diagnostic medical imaging agents and reagents Maetta Specialized in powder injection molding for implants and orthopedic instruments Masimo Canada Manufactures innovative noninvasive patient monitoring technologies, medical devices and a wide array of sensors Medical Plastic Devices Provides precision injection molding services to the healthcare industry MIT Canada Manufacturing and marketing of needle free jet injectors for veterinary and human applications Medtronic Cryocath Catheter-based cryotherapy products to treat cardiovascular diseases MedXL Designs and manufactures medical devices and prefilled syringes Menodys Market innovative medical devices for improved health care SECTOR | MEDICAL TECHNOLOGIES ANNEXES 33 APPENDIX 2 : COMPANIES MEDICAL DEVICES & TECHNOLOGIES (Cont’d) Company Web site Field of activity NexPlasmaGen Portable plasma-based medical instruments for wound healing and skin treatments Noveko International Antimicrobial surgical masks, respirators and air filters derived from its patented antimicrobial filtration technology Octostop Filters for X-ray procedures and systems for pediatric immobilisation Oligo Medic Injectable gels for joint and cartilage repair Optina Diagnostics Ocular imaging system based on super-spectral analysis pDevices Miniature portable plasma based medical diagnostic device Pega Medical Orthopedic instrumentation and pediatric implants Photon etc. Application of hyperspectral analysis to ophtalmology and dermatology Piramal Healthcare Innovation Products based on a biopolymer technology platform for enhancing the process of cartilage regeneration Positech Innovation Cushions, and postural aid systems for to improve clients’ posture while providing them with maximum comfort and autonomy SECTOR | MEDICAL TECHNOLOGIES ANNEXES 34 APPENDIX 2 : COMPANIES MEDICAL DEVICES & TECHNOLOGIES (Cont’d) Company Web site Field of activity QSD Manufacture of seamless compression apparel for post surgical recovery devices, athletic wear and orthopedic garments Rheolution Instruments for the analysis of materials mechanical performance for biomedical applications and the study of biological tissues Roche Diagnostics Canada Range of rapid, reliable instruments and tests for disease screening and diagnosis in laboratories, at the point of care, and for patient self-management Rogue Research Neuronavigation products for application in the fields of cognitive neuroscience, rehabilitation research and veterinary sciences SCIREQ Design and manufacture of precision laboratory equipment and data monitoring systems for preclinical pulmonary research Smith & Nephew Diversified medical technology company Surgmed Manufacturing and distribution of medical supplies and surgical products Synergie Médicale BRG Automated dispensing system for solid oral medication Thought Technologies Manufacturer of instruments for biofeedback, neurofeedback, and psychophysiological studies ZimmerCAS Computer assisted surgical navigation system based on the Orthosoft platform to improve the outcomes of knee and hip replacement surgery SECTOR | MEDICAL TECHNOLOGIES ANNEXES 35 APPENDIX 2 : COMPANIES e-HEALTH & TELEMEDICINE Company Web site Field of activity Aptimed e-learning platform for health professionals in Canada and abroad Bell Solutions Santé Portal for accessing computerized medical records and for the management of chronic diseases; development of mobile clinical carts for tele-health applications. CAE Santé Patient simulators, surgical simulators, imaging simulators and courseware for healthcare professionals Christie Innomed IT clinical systems and products related to medical imaging Fujitsu Canada Services, equipment and software to improve the delivery of healthcare services Groupe CGI Integrator of computerized management systems with applications to the healthcare sector Intelerad Supplier of archiving and image transmission system (PACS) as per DICOM standards Logibec Business software and computer services for the healthcare and social services sectors Manyeta Home-base patient monitoring system which allows systemic monitoring of the patient’s metabolic condition McKesson Canada A complete range of solutions to improve quality, security and cost for patient’s care SECTOR | MEDICAL TECHNOLOGIES ANNEXES 36 APPENDIX 2 : COMPANIES e-HEALTH & TELEMEDICINE (Cont’d) Company Web site Field of activity MediSolution Administrative software designed specifically to meet the operating data of laboratory computerization needs Omnimed Software for the patient’s electronic record including speedy access and management of clinical data PeriGen Provider of fetal surveillance software and systems PHD Medical Products and services to meet specific needs of the home diagnostic and telemedicine markets Purkinje Data management systems for healthcare centers Shimadzu Software Development Canada Development and maintenance of DICOM compliant medical software and image processing methods for the company’s cardiology and RF platforms SOGIQUE Branch of the MSSS to support the management of Quebec healthcare computer network TELUS Santé Specialized telecommunication services for electronic medical files; OASIS transmission systems for laboratory analyses Vigilent Telesystems Software and robotic camera systems used in telemedicine, in teletraumatology and patient’s remote monitoring ZoomMed A clinical interoperable information exchange network between physicians and various other stakeholders of the healthcare sector SECTOR | MEDICAL TECHNOLOGIES ANNEXES 37 APPENDIX 3 : RESEARCH CENTERS & INSTITUTES Centre de recherche – Centre hospitalier de l’Université de Montréal (CHUM) http://crchum.com/crchum.fr.html Contact : Jacques Turgeon, Directeur Centre de recherche – Centre universitaire de santé de McGill (CUSM) http://cusm.ca/research/dashboard Contact : Vassilios Papadopoulos,, D. Pharm., Ph.D., Directeur exécutif et scientifique en chef Centre de recherche – CHU Sainte-Justine http://www.chu-sainte-justine.org/recherche/ Contact : Alain Moreau, Ph.D., Directeur de la recherche Centre de recherche Fernand-Seguin – Institut universitaire en santé mentale de Montréal http://www.iusmm.ca/recherche.html Contact : Sonia Lupien, Ph.D., Directrice scientifique Centre de recherche - Hôpital général juif – Institut Lady Davis de recherches médicales http://ladydavis.ca/fr/home Contact: Roderick R. McInnes, MD, PhD, Directeur Centre de recherche – Hôpital Maisonneuve-Rosemont http://recherche.maisonneuve-rosemont.org/ Contact : Denis Claude Roy, M.D., Directeur SECTOR | MEDICAL TECHNOLOGIES ANNEXES 38 APPENDIX 3 : RESEARCH CENTERS & INSTITUTES Centre de recherche - Hôpital de Montréal pour enfants http://www.hopitalpourenfants.com/la-recherche Contact : Jacquetta Trasler, M.D., Ph.D., Directrice, recherche en santé de l’enfant Centre de recherche – Hôpital du Sacré-Cœur de Montréal http://www.crhscm.ca/ Contact : François Madore, M.D., Directeur de la recherche Centre de recherche – Institut et hôpital neurologiques de Montréal http://francais.mni.mcgill.ca/ Contact : Guy A. Rouleau, M.D., Ph.D., Directeur Centre de recherche – Institut Philippe-Pinel de Montréal http://www.pinel.qc.ca/GeneralList.aspx?NavID=293&CultureCode=fr-CA Contact : Gilles Côté, Ph.D., Directeur Centre de recherche – Institut de cardiologie de Montréal http://www.icm-mhi.org/fr/recherche/propos-centre-recherche Contact : Jean-Claude Tardif, M.D., Directeur Centre de recherche - Institut universitaire de gériatrie de Montréal (CRIUGM) http://www.criugm.qc.ca/ Contact : Sylvie Belleville, Ph.D. Directrice scientifique SECTOR | MEDICAL TECHNOLOGIES ANNEXES 39 APPENDIX 3 : RESEARCH CENTERS & INSTITUTES Centre de recherche - Institut universitaire en santé mentale Douglas http://www.douglas.qc.ca/ Contact : Brigitte L. Kiefer, Ph.D., Directrice scientifique Centre de recherche interdisciplinaire en réadaptation du Montréal métropolitain (CRIR) http://www.crir.ca/?84879747-0EEE-4FA6-878C-B927C1EA76A4 Contacts :Eva Kehayia & Bonnie R. Swaine, Directrices scientifiques Institut de réadaptation Gingras-Lindsay-de-Montréal (IRGLM) http://www.irglm.qc.ca/recherche/la-recherche-a-lirglm.php Contact :Lise Poissant, Directrice de la recherche Institut de recherche clinique de Montréal (IRCM) http://www.ircm.qc.ca/IRCM/Pages/default.aspx?PFLG=1036&lan=1036 Contact : Dr Tarik Möröy, Ph.D., Président et directeur scientifique Institut de recherche Robert-Sauvé en santé et en sécurité du travail du Québec (IRSST) http://www.irsst.qc.ca/ Contact : Marie Larue, Présidente-directrice générale Institut du cancer de Montréal (ICM) http://www.icm.qc.ca/cgi-cs/cs.waframe.index?lang=1 Contact : Anne-Marie Mes-Masson, Ph.D., Directrice scientifique SECTOR | MEDICAL TECHNOLOGIES ANNEXES 40 APPENDIX 3 : RESEARCH CENTERS & INSTITUTES Centre de recherche en sciences et technologies biomédicales (GRSTB) http://www.groupes.polymtl.ca/grstb/ Contact : Michael D. Buschmann, B.Eng., Ph.D., Directeur; michael.buschmann@polymtl.ca Centre PERFORM de l’Université Concordia http://performcentre.concordia.ca/fr/ Contact : Kevin Little, Directeur général; Kevin.Little@concordia.ca Département de génie biomédical de McGill http://www.bmed.mcgill.ca/ Contact: Robert E. Kearney, Président du département; robert.kearney@mcgill.ca Institut de génie biomédical http://www.igb.umontreal.ca/ Contact : Pierre Savard, Directeur; pierre.savard@polymtl.ca Laboratoire de recherche en imagerie et orthopédie (LIO) http://www.etsmtl.ca/Unites-de-recherche/lio/accueil Contact : Jacques A. de Guise, Ph.D., ing. Titulaire; jacques.deguise@etsmtl.ca Laboratoire d'imagerie, de vision et d'intelligence artificielle (LIVIA) http://www.etsmtl.ca/Unites-de-recherche/LIVIA/accueil Contact : Robert Sabourin, Directeur; robert.sabourin@etsmtl.ca SECTOR | MEDICAL TECHNOLOGIES ANNEXES 41 APPENDIX 4 : RESEARCH CHAIRS Chaire industrielle de recherche en technologies intra-auriculaires Sonomax-ÉTS – CRITIAS http://www.etsmtl.ca/Recherche/Chaires-unites-rech/Chaires/Chaire-CRITIAS Contact : Jérémie Voix, Titulaire; jeremie.voix@etsmtl.ca Chaire de recherche du Canada en imagerie 3D et ingénierie biomédicale http://chairei3dib.etsmtl.ca/ Contact : Jacques A. de Guise, Ph.D., Ing., Titulaire; jacques.deguise@etsmtl.ca Chaire de recherche du Canada sur les biomatériaux et implants endovasculaires http://www.etsmtl.ca/Chaires-de-recherche/Chaire-biomateriaux/Accueil?lang=fr-CA Contact : Sophie Lerouge, MÉC, Titulaire; sophie.lerouge@etsmtl.ca Chaire de recherche Marie-Lou et Yves Cotrel en orthopédie du CHUM et de l'Université de Montréal (Soutenue par la Fondation de l'ÉTS) http://en.etsmtl.ca/Unites-de-recherche/LIO/Recherche-et-innovation/Chaires Contact : Jacques A. de Guise, Ph.D., Ing., Titulaire; jacques.deguise@etsmtl.ca Chaire de recherche ÉTS en traumatologie vertébro-médullaire http://www.etsmtl.ca/Recherche/Chaires-unites-rech/Chaires/CRI-traumatologie Contact : Yvan Petit, Titulaire,; yvan.petit@etsmtl.ca SECTOR | MEDICAL TECHNOLOGIES ANNEXES 42 APPENDIX 4 : RESEARCH CHAIRS Chaire de recherche du Canada en communications sans fil à haute vitesse http://www.chairs-chaires.gc.ca/chairholders-titulaires/profile-fra.aspx?profileId=803 Contact : Sofiène Affes, Titulaire; affes@emt.inrs.ca Chaire de recherche du Canada en photonique ultrarapide appliquée aux matériaux et aux systèmeshttp://www.chairschaires.gc.ca/chairholders-titulaires/profile-fra.aspx?profileId=60 Contact : Jean-Claude Kieffer, Titulaire; kieffer@emt.inrs.ca Chaire de recherche du Canada en plasmas appliqués aux technologies de micro et de nanofabrication http://www.chairs-chaires.gc.ca/chairholders-titulaires/profile-fra.aspx?profileId=817 Contact: Mohamad Chaker, Titulaire; chaker@emt.inrs.ca Chaire de recherche du Canada en technologies de l’information dans le secteur de la santé (HEC Montréal) http://neumann.hec.ca/chairetisante/index2.html Contact : Guy Paré, Ph.D. Titulaire; Guy.pare@hec.ca Chaire de recherche du Canada sur les Innovations en santé http://www.medsp.umontreal.ca/crcinnovations/ Contact : Pascale Lehoux, Titulaire; pascale.lehoux@umontreal.ca Chaire de recherche du Canada sur les dispositifs médicaux intelligents (DMI) http://www.polymtl.ca/recherche/rc/unites/details.php?NoUnite=119 Contact: Mohamad Sawan, Titulaire; mohamad.sawan@polymtl.ca