Lab 1
Functional Anatomy of the Endocrine Glands
Exercise 27
Activity 1: Identifying the Endocrine Organs
Activity 2: Examining the Microscopic Structure of Endocrine Glands
Thyroid gland - colloid-filled follicles, follicle cells, and parafollicular cells.
Parathyroid gland - chief cells.
Adrenal gland - cortex and medulla.
Pancreas - islets of Langerhans and acinar cells.
Endocrine System Physiology:
PhysioEx Exercise 28B (in the back
of the lab manual – page PEx-49)
or accessed through Mastering
A&P Chapter 16 Endocrine
System Physiology
Work in groups of 2 or 3
Get a computer and power cord from the cabinet
Plug the computer in and turn it on - and wait until it asks for login information.
Login information is on the keyboard of the laptop.
Put the PhysioEx disc into the disc drive and wait for it to load, or access
Mastering A&P using the Firefox browser.
Select Endocrine System Physiology
Follow directions in the lab manual or from a lab manual at the front desk.
Name____________________________
Lab Section ________________
Review Sheet - This is due at the next scheduled meeting of the lab.
1. Draw and label the following samples: Use colored pencils.
Thyroid Gland100x
Adrenal Gland 40X
Pancreas 100X or 400X
Label using a ruler and pencil:
colloid, parafollicular cells
follicle cells
cortex and medulla
islet cells and acinar cells
2. Hormonal Action: Wet Lab Movie - Watch this movie at home and answer the
following questions.
Hormonal Action – Movie - Endocrinology Experiments
To access the movie online (via DSL or cable)
Go to A and P II in Blackboard
Select Videos and select Endocrinology Experiments
View the first two experiments only – pituitary hormones and insulin
Movie - Experiments in Hormonal Action
1. Pituitary Extract and Frog Ovulation.
a. What are the two main hormones of interest in the frog pituitary extract?
________________ and _______________
b. What is the role of pituitary extract in the frog?
c. What is the control frog in the experiment?
d. Do the data support the hypothesis that pituitary extract is necessary for ovulation?
_____
e. Explain your answer (2 points).
2. Effects of Hyperinsulinism.
a. Describe the fish swimming behavior when it is first put in the water containing insulin.
b. Describe the fish swimming behavior after swimming in the insulin and water for a few
minutes.
c. Where does insulin enter into the fish?
3. Endocrine System Physiology: Computer Simulation – Exercise 28B (in the back of the
lab manual – page PEx-49) or Access through Mastering A&P. This uses the PhysioEx
disc in the lab manual or the PhysioEx link on Mastering A&P.
Read the following instructions, complete Activities 6 and 7 and answer the following. You are
not responsible for other parts of this simulation.
Sample 1 ________________ mg glucose/deciliter
Sample 2 ________________ mg glucose/deciliter
Sample 3 ________________ mg glucose/deciliter
Sample 4 ________________ mg glucose/deciliter
Sample 5 ________________ mg glucose/deciliter
For which patient(s) is the fasting plasma glucose reading in the normal range?
__________________
For which patient(s) is the fasting plasma glucose reading in the diabetic range?
__________________
For which patient(s) is the fasting plasma glucose reading in the impaired range?
__________________
What recommendations would you make to a patient with an impaired fasting plasma glucose
reading who also tested in the impaired range with the oral glucose tolerance test?
____________________________________________________________________________
Patient 3 is pregnant. How might this change the diagnosis? What recommendations would you
make to this patient?
_____________________________________________________________________________
_____________________________________________________________________________
How does the Fasting Plasma Glucose Test differ from the Oral Glucose Tolerance Test?
_____________________________________________________________________________
_____________________________________________________________________________