Warm up • Complete the punnet square for a Tall pea plant. T= tall t=short. – The parents are Tt x tt – What are the genotypes and phenotypes? – What are the genotype and phenotype ratios? Types of Inheritances Pp 237, 242-245 Types of Inheritance • • • • • • Complete Dominance Incomplete Dominance Codominance Sex-linked Polygenic Epistasis You will be responsible to complete punnett squares for the types bolded Complete Dominance • • • • One allele is completely dominant over the other Only two phenotypes exist One phenotype is masked The heterozygous phenotype shows dominant trait – – – – Ex: Tall peas are dominant to short peas TT= tall Tt= tall tt=short Complete Dominance Autosomal Genetic Disorders. Carrier: A heterozygote for a recessive disorder (ex/ Cc). • Carrier does not show symptoms but can pass recessive allele to offspring • Affected person must inherit two recessive alleles • Example Cystic Fibrosis, Tay-sachs, sickle-cell anemia • CC &Cc = unaffected • cc = affected Incomplete Dominance • Neither allele is completely dominant over the other Incomplete Dominance • Neither allele is completely dominant over the other • Three phenotypes exist • The heterozygous phenotype shows blended trait Incomplete Dominance • Neither allele is completely dominant over the other • Three phenotypes exist • The heterozygous phenotype shows blended trait • Ex: Flowers can be pink, red, or white. – RR=red – rr= white – Rr=pink Incomplete Dominance • Cross two pink flowers – Draw Punnet Square • What percent of their offspring will have white flowers? Incomplete Dominance • Cross two pink flowers • What percent of their offspring will have white flowers? • Fish can be green (GG), blue (BB), or teal (GB) Green (GG) Teal (GB) Blue (BB) Codominance • • • • Both alleles are dominant Three phenotypes exist Neither phenotype is masked The heterozygous phenotype shows both traits at once Codominance • • • • Both alleles are dominant Three phenotypes exist Neither phentoype is masked The heterozygous phenotype shows both traits at once. X red (RR) = white (WW) Codominance • • • • Both alleles are dominant Three phenotypes exist Neither phentoype is masked The heterozygous phenotype shows both traits at once. (Not a blend) X red (RR) = white (WW) red & white(WR) Codominance EX: In Smileys, eye shape can be starred, circular, or a circle with a star. Write ALL the phenotypes and genotypes that exist. Codominance EX: In Smileys, eye shape can be starred, circular, or a circle with a star. Write ALL the phenotypes and genotypes that exist. • CC = circle SS = star SC = circle-star Homework • Incomplete Dominance WS – 3 pages – Must be colored for credit. Warm-up 12/11 • A Blue flower is crossed with a Yellow flower. – What are the offspring colors and their predictided ratios if: (Show Punnet squares) • Blue is codominant with Yellow • Blue and Yellow exhibit incomplete dominance • Blue is completely dominant over Yellow • Quiz Friday on Genetics • Study Guide Due Thursday 12/19/13 Sex Linked • Disorder/trait found on the “X” chromosome • Which gender has more instances of having an x-linked disorder? • Men-Males have no second copies of X-linked genes (XY). • Females have two X chromosomes (XX) so if one has a defect they can use the other normal X chromosome. Sex-Linked • • • • EX: color blindness Punnett square determines sex and trait First, Use X and Y to show gender Second, use a letter on the X chromosome to show which allele they inherited. • “Y” has to come from father • “XR or Xr” vs just “R or r” Sex-Linked • • • • EX: color blindness Punnett square determines sex and trait First, Use X and Y to show gender Second, as a letter on the X chromosome to show which allele they inherited. Possible genotypes and phenotypes: XR XR = Female, normal vision XR Xr = Female, normal vision Xr Xr = Female, color blind XR Y = Male, normal vision Xr Y = Male, color blind • Sex Linked What percentage of offspring would be color blind if a female carrier and a male who has normal vision had children? Sex Linked What percentage of offspring would be color blind if a female carrier and a male who has normal vision had children? Step 1: Determine genotype of parents ____________ x ____________ Sex Linked Step 2: set up and complete punnett square. What percent of their children would be colorblind? XR Y • Possible genotypes and phenotypes: XR XR = normal vision XR Xr = normal vision XR Xr Xr Xr = color blind XR Y = normal vision XRY XrY Xr Y = color blind XRXR XRXr Single gene traits • controlled by only one gene - complete, incomplete, and codominant EX. Huntington Disease (D/d), Sickle Cell Anemia (N/S) , Cystic Fibrosis (R/r) Polygenic traits • controlled by additive effects of two or more genes EX. Skin color (controlled by 3-6 genes), eye color - each gene is responsible for adding pigment Polygenic • Many genes may interact to produce one trait • Ex: Skin color result of four genes that interact to produce range of colors Epistasis • One gene controls many traits • EX: Albinism • Albinos are unable to synthesize melanin, the pigment molecule responsible for most human coloring Multiple allele trait • controlled by more than two alleles in one gene • Still only inherit one copy from each parent for a total of two alleles but have a few to combine EX. Blood type: Homework • Sex Linked Traits – In Packet Warm up 12/12 • Liking Brussels Sprouts is a recessive characteristic. – What are the possible genotypes for an individual who: • likes Brussels sprouts. • hates Brussels sprouts. – A man who hates Brussels sprouts wants to find out if he is heterozygous or homozygous. Should he find a mate who likes Brussels sprouts or one who hates Brussels sprouts. Explain your answer with a punnet square! Test Cross • Used to determine if a dominant parent’s genotype is Bb or BB • Cross with homozygous recessive (bb) • If in the offspring, there are bb, then the parent had to be Bb Blood Typing Trait controlled by multiple alleles, with two that are codominant and one “null” Dominant Allele: I 2 Dominant Alleles: A: IA B:IB Recessive Allele: i 1 Recessive Allele: O= i • Trait controlled by multiple alleles, with two that are codominant and one “null” • Trait controlled by multiple alleles, with two that are codominant and one “null” • Example: Blood Types • Trait controlled by three alleles, with two that are codominant and one recessive IA : produces A antigens on surface of cell IB : produces B antigens i: does not produce antigens Practice Problem • What possible blood types could the children of a homozygous A female and a male with AB blood have? • Parents Genotype _______X ________ • Someone with AB blood can receive blood from A, B, AB, and O because it doesn’t have antibodies to clump cells. However it can only be giving to AB because all other blood types have antibodies that can cause clumping with the AB cell. • Use serums that contain these antibodies to test blood type Testing Blood Type • Use anti-A serum and anti-B serum • If you use anti-A serum and it clumps then it has A antigens (proteins), if you use anti-B serum and it clumps then it has B antigens • No clumping = no antigens What blood type would this be? Homework • Blood Type Problems • Friday: Quiz – Genetics • Punnet Squares, Complete, Incomplete & Codominance – Mitosis & Meiosis • Know Phases, Haploid, Diploid, Nuclear State • Exam: Friday Dec. 20th – Intervention: Wednesday 12/18 @ 2:45-3:30 pm & Thursday 12/19 @ 6:50 -7:35 am Homework • Read 237 -242 • Problems p 240 #1-6 • P 251 # 1, 4, 5, 6