Arizona Department of Health Services/ Division of Behavioral Health Services Behavioral Health Drug List Effective 01/01/2014 The Arizona Department of Health Services, Division of Behavioral Health Services, the “Department”, is pleased to provide the Behavioral Health Drug List (BHDL) which will serve as the foundation for the medications prescribed by our Contractors’ Providers throughout the State. The BHDL contains all of the behavioral health medications listed on each (Tribal) Regional Behavioral Health Authority’s ((T)RBHA) behavioral health drug list and specifies which medications require prior authorization. The BHDL also specifies that there are age restrictions for some medications. Providers prescribing medications outside of the age limit parameters are required to submit a prior authorization to the recipient’s (T)RBHA. The drugs listed in the BHDL are intended to provide clinically appropriate, evidenced-based, cost-effective medication options, for all eligible recipients receiving services through the Department and its Contractors. The drugs listed on the BHDL have been reviewed and approved by our Pharmacy and Therapeutics (P&T) Committee. However, the BHDL is not intended as a comprehensive listing of all drugs that may be reimbursed by the Department. If a drug is not listed on the BHDL and is determined to be medically necessary for a behavioral health diagnosis, it may be requested through the (T)RBHA Prior Authorization process. Providers and recipients may contact the (T)RBHA that is responsible for their pharmacy benefit to request more information about the process for medications not listed on the BHDL. Pharmacy and Therapeutics (P&T) Committee The P & T Committee is composed of clinical staff from the Department and each of its Contractors. This committee meets at least quarterly to discuss a variety of clinical issues, which pertain to drug selections, including formulary additions, deletions and changes as well as pharmacy program management. The P&T Committee evaluates clinical information for newly marketed drugs within 180 days of market launch. Current medications are reviewed on an annual basis. The evaluation may include, but is not limited to, the following review categories: Safety Efficacy Comparative data and studies FDA approved indications Treatment and consensus guidelines Adverse events Contraindications/Warnings/Precautions Pharmacokinetics Dosage frequency and formulations Patient administration/compliance considerations Medical outcome and pharmacoeconomic studies When a new drug is considered for inclusion on the BHDL, it will be reviewed relative to similar drugs that are currently included on the BHDL. The review process of a therapeutic class continually promotes the most clinically appropriate, useful, and cost-effective agents. All of the information in the BHDL is provided as a reference for drug therapy selection. Specific drug selection for an individual member rests solely with the prescribing clinician. As a reminder, the (T)RBHA Providers are required to utilize the most cost-effective (least costly) clinically appropriate pharmaceutical treatment. 1 revised 8/5/2013 Generic Drugs The Department supports the use of generic medications. As a general rule, brand name medications will require Prior Authorization as noted in the BHDL and when a generic equivalent is available for a branded drug. The BHDL is organized by sections. Each section includes therapeutic groups identified by drug class. Products are listed with the generic name in lower case and brand name medications are listed in bold capitals. Generics drugs are to be considered as the first line of prescribing. The Department and its Contractors are required to use the most cost-effective (least costly) clinically appropriate pharmaceutical treatment. Quantity Limits The BHDL does not specify medication Quantity Limits. The Department allows its Contractors to develop their own Quantity Limit parameters, and these can be located on each Contractor’s website. The Department, in consultation with its Contractors, has developed prior authorization criteria for evaluation of medication dosages that exceed the FDA Allowable Maximum. Key: Drugs listed in Bold/Italic CAPITAL LETTERS indicate the medication is only available as a brand name product. (*) Indicates that medication can only be obtained from an Opioid Treatment Program (OTP) provider. (X) Indicates that the medication is only available through the (T)RBHA prior authorization process. Abbreviations: Cap = capsule Chew = chewable Conc = concentrate DR = Delayed Release Elix = Elixir ER = extended release hbr = hydrobromide hcl = hydrochloride IM = intramuscular Inj = injectable IR = Immediate release LA = long acting ODT = orally disintegrating tablet SL = sublingual SOLN = solution SR = sustained release Susp = suspension Syr = Syrup Tab = tablet TD = transdermal XL = extended release 2 revised 8/5/2013 ANTIDEPRESSANTS Alpha-2 Receptor Antagonist Antidepressants Remeron mirtazapine Remeron SolTab Monoamine Oxidase Inhibitors (MAOIs) EMSAM seligilene Marplan isocarboxazid Nardil phenelzine sulfate Parnate tranylcypromine sulfate Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs) APLENZIN bupropion hbr Wellbutrin Wellbutrin SR Wellbutrin XL bupropion hcl Selective Serotonin Reuptake Inhibitors (SSRIs) Various citalopram hbr Celexa citalopram hbr Lexapro escitalopram oxalate Lexapro escitalopram oxalate Prozac fluoxetine hcl Prozac fluoxetine hcl Prozac Weekly fluoxetine hcl Luvox fluvoxamine maleate Luvox CR fluvoxamine maleate Paxil paroxetine hcl Paxil paroxetine hcl Paxil CR paroxetine hcl tab PEXEVA Paroxetine mesylate Zoloft sertraline hcl Zoloft sertraline hcl VIIBRYD vilazodone hcl Serotonin-2 Antagonist/Reuptake Inhibitors (SARIs) Various nefazodone Various trazodone hcl OLEPTRO trazodone hcl Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) PRISTIQ desvenlafaxine CYMBALTA duloxetine hcl Effexor venlafaxine hcl Effexor venlafaxine hcl 3 Additional Information Quantity Limit Prior Authorization Required Brand Reference Name Age Limitation Generic Name Formulation(s) Medication Tab ODT TD Patch Tab Tab Tab X ER Tab IR Tab ER Tab ER Tab X Soln Tab Soln Tab Cap / Tab Soln DR Cap Tab ER Cap Susp Tab ER Tab Tab Conc Tab Tab Tab Tab ER Tab ER Tab Cap Tab ER Cap X X X X X revised 8/5/2013 Various venlafaxine hcl ER Tab Tricyclic Antidepressants & Related Non-Selective Reuptake Inhibitors Various Tab amitriptyline hcl Various Tab amoxapine tab Anafranil Cap clomipramine hcl Norpramin Tab desipramine hcl Various Cap doxepin hcl Various Conc doxepin hcl SILENOR Tab doxepin hcl Various Tab imipramine Tofranil-PM Cap imipramine hcl Various Tab maprotiline hcl Pamelor Cap nortriptyline hcl Various Soln nortriptyline hcl Vivactil Tab protriptyline hcl Surmontil Cap trimipramine maleate Combination Medications Used for the Treatment of BPAD Symbyax Cap fluoxetine hcl /olanzapine ANTIPSYCHOTICS 1st Generation Antipsychotics Various Tab haloperidol Haldol Inj haloperidol decanoate Various Conc haloperidol lactate Loxitane Cap loxapine succinate ORAP Tab pimozide Navane Cap thiothixene 2nd Generation Antipsychotics ABILIFY Tab aripiprazole ABILIFY DISCMELT ODT Tab aripiprazole ABILIFY MAINTENA Inj aripiprazole ABILIFY Soln aripiprazole Clozaril Tab clozapine FazaClo ODT Tab clozapine FANAPT Tab Iloperidone INVEGA ER Tab paliperiodone INVEGA SUSTENNA LA Susp paliperidone LATUDA Tab lurasidone hcl 4 Additional Information Quantity Limit Prior Authorization Required Brand Reference Name Age Limitation Generic Name Formulation(s) Medication X X X X X X X X X X X X X X X X X X X X X X X X X X revised 8/5/2013 olanzapine quetiapine quetiapine risperidone risperidone risperidone risperidone asenapine maleate ziprasidone hcl Phenothiazine Antipsychotics chlorpromazine hcl fluphenazine decanoate fluphenazine hcl fluphenazine hcl fluphenazine hcl perphenazine thioridazine hcl trifluoperazine hcl ANTICONVULSANTS Various Various Tab Inj Oral Conc Elix Tab Tab Tab Tab X X Various Various Various Various Various Various Tegretol, Epitol Carbatrol, Equetro Tegretol XR, Tegretol divalproex divalproex gabapentin gabapentin gabapentin gabapentin Depakote Depakote Sprinkles Neurontin HORIZANT Neurontin GRALISE Lamictal LAMICTAL XR Trileptal Tab Chew ER Cap ER Tab Susp DR & ER Tab Cap Cap ER Tab Soln Tab Tab Chew ODT ER Tab Susp Additional Information X X X X X X X X X Quantity Limit ODT Tab Tab Tab Inj ODT Soln SL Tab Cap Prior Authorization Required Zyprexa Zydis Seroquel SEROQUEL XR Risperdal RISPERDAL CONSTA Risperdal M-TAB Risperdal SAPHRIS Geodon carbamazepine carbamazepine carbamazepine carbamazepine lamotrigine lamotrigine oxcarbazepine 5 Age Limitation Generic Name Brand Reference Name Formulation(s) Medication X X X X X X X X X X X revised 8/5/2013 oxcarbazepine valproate sodium Trileptal Various valproate sodium ANTIMANIC AGENTS lithium carbonate lithium carbonate lithium citrate ADHD DRUGS Amphetamines amphetaminedextroamphetamine amphetaminedextroamphetamine dextroamphetamine sulfate dextroamphetamine sulfate lisdexamfetamine dimesylate Stimulants dexmethylphenidate hcl dexmethylphenidate hcl methylphenidate hcl Depakene Tab Soln Cap / Syrup Various Lithobid Various Cap ER Tab Soln methylphenidate hcl methylphenidate hcl methylphenidate hcl methylphenidate hcl methylphenidate hcl methylphenidate hcl methylphenidate hcl Miscellaneous Agents atomoxetine Central Alpha-Agonists clonidine hcl clonidine hcl clonidine hcl guanfacine hcl 6 Adderall Adderall XR Tab SR Cap ER Cap Dexedrine Tab Various Additional Information Quantity Limit Prior Authorization Required Age Limitation Generic Name Brand Reference Name Formulation(s) Medication X X X X VYVANSE ER Cap X Focalin FOCALIN XR Ritalin X X X METHYLIN Ritalin LA / Metadate CD Ritalin SR Concerta DAYTRANA METHYLIN QUILLIVANT XR Tab ER Cap Tab Chew Tab ER Cap SR Tab ER Tab TD Patch Soln Susp STRATTERA Cap X Catapres KAPVAY Catapres TTS Tenex Tab ER Tab TD Patch Tab X X X X X X X revised 8/5/2013 guanfacine hcl SUBSTANCE ABUSE Opiate Agonists/Partial Agonists buprenorphine hcl buprenorphine hcl / naloxone buprenorphine hcl / naloxone methadone Opiate Antagonists naltrexone naltrexone Miscellaneous Agents acamprosate disulferam ANXIOLYTICS AND HYPNOTICS Benzodiazepines alprazolam Subutex Additional Information X SL Tab SL Tab Suboxone Film SUBOXONE FILM X * Dolophine Revia VIVITROL Tab Inj CAMPRAL Antabuse DR Tab Tab Xanax Tab Conc Soln ER Tab ODT Cap Tab ODT Tab Tab Conc Soln Tab Cap Tab Conc Soln Cap Cap alprazolam intensol alprazolam alprazolam chlordiazepoxide hcl clonazepam clonazepam clorazepate dipotassium diazepam Alprazolam Intensol Xanax XR Niravam Librium Klonopin Various Tranxene-T Valium diazepam intensol estazolam flurazepam hcl lorazepam Diazepam Intensol Various Dalmane Ativan lorazepam Lorazepam Intensol Serax oxazepam Restoril temazepam Miscellaneous Anxiolytics, Sedatives & Hypnotics Various buspirone hcl 7 Quantity Limit ER Tab Prior Authorization Required INTUNIV Age Limitation Generic Name Brand Reference Name Formulation(s) Medication X Tab revised 8/5/2013 eszopiclone meprobamate ramelteon triazolam zaleplon capsule zolpidem zolpidem LUNESTA Various ROZEREM Halcion Sonata Ambien Ambien CR INTERMEZZO SL / EDULAR ZOLPIMIST zolpidem zolpidem ANTIHISTAMINES Various cyproheptadine hcl Various diphenhydramine Various diphenhydramine hcl Atarax hydroxyzine hcl Vistaril hydroxyzine pamoate DOPAMINE AGONISTS Various amantadine hcl AUTONOMIC AGONISTS Parasympathomimetic (Cholinergic) Agents Urecholine bethanechol chloride Anticholinergic Agents Cogentin benzotropine mesylate Artane trihexyphenidyl hcl CARDIOVASCULAR DRUGS Alpha-1 Adrenergic Blocking Agents Minipres prazosin hcl Beta-Adrenergic Blocking Agents Corgard nadolol tab Inderal propranolol hcl THYROID AGENTS Levothroid / Synthroid levothyroxine sodium Cytomel liothyronine VITAMINS AND OTHER MISCELLANEOUS AGENTS Vitamin E – Various alpha-tocopherol Vitamin B12 - Various cyanocobalamin Various folic acid Various omega 3 fatty acids Vitamin B6 - Various pyridoxine hcl 8 Tab Tab Tab Tab Cap Tab ER Tab SL Tab Soln Additional Information Quantity Limit Prior Authorization Required Age Limitation Generic Name Brand Reference Name Formulation(s) Medication X X X X Tab Cap / Tab Elix / Syr Tab / Syr Cap Cap / Tab Tab Tab Tab Cap Tab Tab Tab Tab Cap Tab Tab Cap Tab revised 8/5/2013 Vitamin B1 - Various thiamine hcl Various multiple vitamin multiple vitamin / Various minerals Miscellaneous Ear, Nose & Throat Drug Salivart saliva substitute Cathartics and Laxatives Colace docusate sodium Metamucil psyllium 9 Additional Information Quantity Limit Prior Authorization Required Age Limitation Generic Name Brand Reference Name Formulation(s) Medication Tab Tab Tab Spray Cap Powder revised 8/5/2013