Healthy Ways to Deal with Chronic Pain: An Acceptance and Commitment Therapy Perspective Steven C. Hayes University of Nevada My Goal • To explore briefly our view of chronic pain • To provide an alternative, evidence based approach that applies not just to pain but to behavioral health treatment generally • To show some data • To work with a very small set of methods • To interest you in exploring the area Is Pain the Issue or is it Our Relationship to Pain • In the case of acute pain, pain is clearly a focal issue • But chronic pain may be a very different issue Immersion in Struggle • For many of those with chronic pain, pain intensity has been the focus of years of struggle … and yet it seems virtually untreatable. The data are hardly reassuring. . . Chronic Pain • is extremely common e.g., Breivik et al., 2006; Gureje et al., 1998 • remits in only a minority of cases e.g., Andersson, 2004; Elliott et al., 2002 • does not reliably respond to our clinical arsenal over the longer term e.g., Eccleston et al., 2009; Hoffman et al., 2007; Martell et al., 2007; Chou et al., 2007; Armon et al., 2007; Kemler et al., 2000; 2008 • Opioids – No evidence of long-term pain reduction (i.e., > 15 weeks). Martell et al., 2007 – Ann. of Internal Medicine – Systematic Review Chou et al., 2007 - Ann. of Internal Medicine – Clinical Guidelines • Surgery - Continued pain and disability are the norm following spinal surgery (i.e., discectomies & fusions). Franklin et al., 1994; Hoffman et al., 1993; Turk, 2002; Turner et al., 1992; 1995 • Spinal Cord Stimulators - Pain reduction is relatively transient (absent @ 3, 4, & 5 year f/u). No evidence of improvement in functioning or quality of life. Kemler et al., 2000 NEJM; 2002 J Neurosurgery; 2006 NEJM; 2008 J Neurosurgery • Epidural Steroid Injections – – Lumbar - “Probably not” effective for long-term pain relief, for improving functioning, or decreasing rates of surgery. – Cervical – Not enough evidence yet available upon which to base a conclusion. Armon et al., 2007., Neurology – Systematic Review & Clinical Guidelines commissioned by the Amer. Acad. of Neurology Pain and Functioning • Studies find very limited evidence for a relationship between reported pain intensity and direct measures of – – – – daily activity medication use health care use, or observed behavior. E.g., Physical Ability ∆ Pain-Related Fear ∆ Pain Intensity 25 % Variance (r-square) 20 15 10 5 0 ∆ Floor to Waist Lift Vowles & Gross, 2003, Pain ∆ Waist to Shoulder Lift Future Work Status • Following treatment (6 months later): – Degree of pain was a nonsignificant predictor (posttreatment depression level predicted 28% of the variability) • Vowles, Gross, & Sorrell, 2004, Euro J Pain • In the absence of treatment (4 months later): – Pain accounted for 0.3% of variance (nonsignificant), while pain related acceptance accounted for 14.0% (p < .001). • McCracken & Eccleston, 2005, Pain Data Like These Raise a Question . .. • What are we treating? Treatment Options • There seem to be few evidence-based reasons to focus on pain per se • We should focus on meaningful functioning in the context of the person’s total life situation, including pain when there is pain • That is the ACT approach The Problem is That We All Normally Think Pain Suffering Therefore, for pain patients … • “Its important to keep fighting this pain.” Is endorsed by 92% of patients! McCracken, Vowles, & Eccleston, 2004, Pain That is Shocking Because Persistent Struggling With Pain is … • Single best predictor of, now and over several months prospectively: – – – – – Worse Pain Lower Levels of Activity Greater Disability Worse Depression Greater Avoidance McCracken, Eccleston & Bell, 2005, Eur J Pain McCracken, Vowles, & Gauntlett-Gilbert, 2007, J Behavioral Med Vowles & McCracken, 2010, Beh Res & Therapy Willingness and Acceptance • My tinnitus as an example A Larger System Supports This Link Pain Suffering The System Creating Suffering Pain Suffering Multiplied Struggling with Pain Lost Freedom & Opportunity Failure The Cycle of Suffering Pain Suffering Multiplied Struggling with Pain Lost Freedom & Opportunity Failure The Cycle of Suffering More Pain Suffering Multiplied Struggling with Pain Increase Pain Focus & Lost Freedom & Opportunity Failure Breaking the Cycle of Suffering SelfCompassion And Life Direction Lost Freedom & Suffering Opportunity Multiplied Pain Failure Breaking the Cycle of Suffering Pain Maintained Life Direction Freedom & Opportunity Suffering Multiplied Failure Breaking the Cycle of Suffering Pain Maintained Life Direction Freedom & Opportunity Suffering Multiplied Success Breaking the Cycle of Suffering Pain Maintained Life Direction Freedom & Opportunity Suffering Reduced Success Breaking the Cycle of Suffering Pain? Maintained Life Direction Freedom & Opportunity Suffering Reduced Success The Impact of That Approach • Listed by APA as having “strong research support” as a evidence-based approach • The only approach listed by APA as generally applicable to all kinds of pain • 7 RCTs (~ 360 patients) and 7 open trials (~950 patients, up to 3 yr follow up) Chronic Pain Dahl, Nilsson & Wilson, Behavior Therapy, 2004 20 public health caretakers at risk for developing long-term pain/stress symptoms 10 TAU, 10 ACT protocol, 4 sessions at worksite/home Baseline=60 days, intervention: 4 1-hr sessions over 30 days, FU 60 days 2 therapists: 1 experienced CBT, 1 nurse Cumulative Sick Leave Average Total # Sick Days 80 70 60 ACT TAU 50 Cohen’s d at follow-up = 1.00 40 30 20 10 6 FU m o 4 FU m o 2 o m FU rv en ti o n 5 In te B L m o 3 o m L B B L m o 1 0 Pediatric Pain Wicksell et al, 2009 • 32 patients w/ longstanding pediatric pain • 25 female; ~ 15 y o, 32 mo pain duration • Randomly assigned to ACT or multidiscipinary Rx & amitriptyline (MDT). 2 drop outs. • Pre / post / 3.5mo f-up / 6.5 mo f-up Content of Treatment • ACT = 10 individual, 1-2 parental over 4 mo; on average 13 sessions thru f-up • MDT = About 10 individual + parents sessions; medication titrated and continued for 10 mo, with addition meetings with team throughout; on average 22.8 sessions through follow up Between Effect Sizes (p eta sq) Post • • • • • • • • Fight with pain Pain intensity Pain interference Physical health Mental health Depression Fear of movement Pain related worry .29*** .13** .16** .03 .15** .12* .21*** .34*** * p < .1; **p < .05; *** p < .01; medium = .09; large = .25 F-Up .23*** .13** .09 .05 .11* .10* .12* .15** Pain Interference 6 MDT 4 ACT 2 Pre Post 3.5 mo 6.5 mo Whiplash Wicksell et al, 2008 • 21 patients with whiplash associated disorder. • 11 female; ~ 42 y o, 83 mo pain duration • Randomly assigned to ACT or wait list. One wait list drop out. • Pre / post / 4mo f-up / 7 mo f-up in Rx arm Between Effect Sizes (p eta sq) Post through F-U • • • • • • Pain disability Life satisfaction Fear of movement Depression Pain intensity Pain interference All p < .01 except as indicated; medium = .09, large = .25 .44 .40 .40 .60 .01 n.s. .31 Satisfaction w Life Scale For Example, Life Satisfaction 25 ACT 20 TAU 15 Pre Post 4 Month Follow Up Chronic Pain McCracken, Vowles, & Eccleston, BRAT, 2005 Effectiveness trial: 108 chronic pain patients Average of 132 months of Chronic pain 6.3 treatment programs Multidisciplinary in-patient program Within subject analysis: Preassessment; 3.9 months later (on average) pretreatment assessment; 3-4 week residential program; 3 month follow-up Pa in De I pre n ten sity Pa s si inon r el ( BD ate I) Ph da ys i n Ps x ie ca y ch lD ty os is a oc bili ial ty Dis ab Pa ility Pa in in Re Me s tin dic g a ti on Us e GP v is it s Tim ed Wa S it lk - St an d /m in Percent Improvement Impact on Chronic Pain Ass't to Pre (M=3.9 mo) and Pre to F-Up (M=3.9 mo) 50% 40% 30% 20% 10% 0% -10% Three Year Follow Up Vowles, McCracken & O’Brien, BRAT, 2011 108 chronic pain patients treated with ACT Follow up data at three month and 3 years Effect Sizes at 3-36 Mo. Follow Up Small Medium Large Acceptance 3 Month Follow Up Values Success 36 Month Follow Up Values Discrepancy Pain Depression Pain-Related Anxiety Physical Disability Psychosocial Disability Medical Visits .2 .5 .8 1.1 1.5 A Quick Note Before We Leave Data • One reason nurses may want to consider learning ACT: • There are good effects from very short ACT interventions in the management of diabetes, exercise, weight, epilepsy, MS, cancer treatment and many other areas in addition to mental health And by The Way • We have local projects coming together right now in post partum depression and hypertension (if you might be able to help email me: hayes@unr.edu) ACT for Diabetes Management Gregg, Callaghan, Hayes, & Glenn-Lawson, 2008, JCCP • Randomized controlled trial with poor, mostly minority clients • 40 / group: ACT plus diabetes education (one sixhour workshop) or diabetes education (also a six hour workshop) • Pre, post, 3-month follow-up 3/12/2016 Level 3 Process Evidence Change (Pre to Follow up) AAQ (Diabetes) % in Diabetic Control SelfManagement 10 50% 50% 5 25% 25% 0 0% 0% Ed’n ACT Ed’n ACT AAQD and Self-Management mediate blood glucose outcomes Ed’n ACT Psychological Adjustment Among Cancer Patients: ACT and CBT Rost, Wilson, Hildebrandt, & Mutch, in press • Stage 4 cancer patients randomly assigned either to ACT or to a form of traditional CBT (cognitive restructuring plus relaxation): 30 / group • 12 sessions with each participant during chemotherapy visits: pre and sessions 4, 8, and 12. • No follow up, in part due to the relatively high likelihood of death (12 died during the study) Impact on Distress (POMS) (change scores) CBT 0 Session 12 d = .9 -20 ACT -40 Pre Session 4 Session 8 Session 12 Wilks’ Lambda=.722, F(3,29)=3.722, p=.022 My Point: It is Worth Learning • I will give to a link to a society that will help you do just that if you are interested • Indeed, a nursing SIG is forming in that society 3/12/2016 The ACT Model Contact with the Present Moment Acceptance Values Psychological Flexibility Defusion Committed Action Self as Context The two-minute Persuasion Exercise • Speaker – Think of something you want to change, but still have some ambivalence about. – Perhaps something related to a health area (smoking, diet, exercise), recreation (TV watching, hobby), or work (study more, change jobs). – If none of this applies personally, role play someone you know but don’t say which is which • Clinician: – Put yourself in the mental state in which you have a good understanding of the speaker’s problem, and you know what he/she needs to do to address the problem. – Even if this is not your style, play this out The clinician’s task: Persuade the client to change! Try strategies such as: - Explain why it is important to change. - Warn of the consequences of not changing. - Sympathize. - Reassure your client that change is possible. - Disagree if the client argues against change (confront denial). - Try to make the patient see the damage being done by her/his current behavior. - Towards the end of the “session,” tell your client what to do. Why a “Psychological” Approach Not because pain: • Is a mental problem / in people’s heads. • Is affected by moods or thoughts • Causes distress • Leaves no other alternative But because: • People with pain want to live free and full lives • Participation in life is about action • Successful treatment entails behavioral change A Place to Start • Mindful Listening – Reflective listening that fosters perspective taking and a gradual focus on meaning and purpose – “Is this what you meant?” – Look at the person; slow the pace; take the time to share consciousness Reflect and Look for Meaning • Repetition – Repeat an element – “You want some help.” • Rephrasing – Repeat with synonyms – “Sounds like you are really suffering and want someone to do something about it.” • Reflection of feeling – paraphrase emphasizing emotional dimension. – “This sounds as if its very important to you.” • Paraphrase – best guess at meaning. – “You are hoping that the work we do here today will bring some meaning back in to your life.” Exercise – Part II • Speaker: You still want to change. • Listener: Listen reflectively. • Speaker: Can respond with elaboration. Listening Tips • Guess at what they mean. – (It’s ok to be wrong) • Experiment with statements (questions are ok too). – “Sounds like . . . ” – “You are wondering if . . . ” – “You are feeling (thinking, hoping, etc.)” – Express genuine empathy but no wallowing • Can start w/simple reflections and then use advanced • Repetition – Repeat an element • Guess at what they mean. – (It’s ok to be wrong) – “You want some help.” • Experiment with statements (questions are ok too). synonyms – “Sounds like . . . ” – “Sounds like you are really – “You are wondering if ...” suffering and want someone to do something about it.” – “You are feeling (thinking, hoping, etc.)” Reflection of feeling – – Express empathy paraphrase emphasizing emotional dimension. • Can start w/simple reflections – “This sounds as if its very important to you.” and then use advanced • Rephrasing – Repeat with • • Paraphrase – best guess at meaning. – “You are hoping that the work we do here today will bring some meaning back in to your life.” A Focus on Values – Form an answer to the questions: • “What do you want your life to stand for?” • “What brings meaning to life?” Example Values Domains • Friends • Self Development/Learning • Family Relationships • Recreation / Leisure • Intimate Relationships • Spirituality • Work / Career • Citizenship / Community • Education / Learning • Health / Well-Being Exercise – Part III • Speaker – Why is this important to you? – If you did that, what would that allow you to do? • Clinician – Listen, Reflect, Ask for clarification. • Please: – Slow down – Recognize that this is likely to be important – Listen, don’t solve A Model for Treatment Improved willingness to have the experience of pain + More frequent engagement in valued activity over the longer term = Progress Learning ACT Join ACBS www.contextualpsychology.org There are about 60 books available including three in the area of chronic pain QUESTIONS? • Email: hayes@unr.edu • ACBS www.contextualpsychology.org • The next large conference is WorldCon X in DC, July 21-25