Hardy Weinberg Analysis

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Hardy Weinberg Analysis
Due Thursday, October 8th
Case 1 Analysis
 In your lab book, compare your small population data with
your large population.
 Press F9 a few times to simulate a few different trials.
 Record all of your observations
 Describe what you are seeing (qualitative) in your computer
model. What forces could be acting upon this? Is it truly in
H-W equilibrium? Why or why not?
Case 2 Analysis- Natural Selection
 In your lab book, compare your data for Natural Selection after
5 generations with your computer model with 1000
individuals after 5 generations.
 Press F9 a few times to simulate a few different trials.
 Record all of your observations
 Describe your comparison.
Case 3 Analysis-Independent
Investigation
 Choose another condition to model. Examples include:
 Gene Flow
 Mutations (the dominant becomes recessive)
 Heterozygote Advantage
 Non-random mating
 Press F9 a few times to simulate a few different trials.
 Record all of your observations
Case 3: Independent Investigation
 You will complete a full investigation and create a mini-
poster.
1. Determine your question (non-random mating, gene flow,
mutation).
2. Record your review of literature (text book).
3. Formulate your hypothesis.
4. Record your procedure. This includes:
1.
2.
Your scenario for the change
Your formula that models that change.
Analyze your data
6. Write a brief conclusion.
5.
Example scenario…
 If I were to use natural selection:
 There is a population of bakerbugs.
 In Bakerbugs, following the proper rules of “simon says” is
dominant (A) and following the new weird rules of “Nibbly
Bibble” is recessive (a).
 All of a sudden, the environment changes. Those who are
homozygous recessive and those who are heterozygous survive,
but those who are homozygous dominant only survive 25% of
the time.
 You need to express this in a formula in order to model it
through the generations.
And formula
 Original formula:
 A alleles = AA*2+AB
 B alleles = BB*2+AB
 New Formula
 A alleles = (AA*2*.25)+AB (“.25 represents the 25% that
survived)
 B Alleles stays the same
 Tips- if your formula gives you alleles in a decimal, reformat
the cells to round them to a whole number; you can’t have part
of an allele in a population.
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