Contemporary Drug Trends – Salvia, Spice, Bath Salts, and more… Sgt. Craig Simpson Colorado Springs PD Some common “uncommon” drugs Salvia Divinorum K-2 / Spice “Bath Salts” Salvia Divinorum Salvia Divinorum A powerful (and, in many states, legal) hallucinogenic herb Referred to most commonly as “Salvia”, although terms “Magic Mint”, and “Diviner’s Sage” are used as well There are many different species and varieties within the Salvia genus The “Divinorum” variety is not found in garden stores, but other varieties of Salvia are Plant is related to Sage and Mint Quick Facts Active ingredient is Salvinorin-A which is a powerful hallucinogen “As potent as LSD, and essentially, the most potent naturally occurring hallucinogenic drug” Dr. Bryan Roth, Director National Institute of Mental Health’s Psychoactive Drug Screening Program Used recreationally since early 1990’s Use For recreational users, the dried leaves of the plant are generally smoked Fresh leaves may be chewed Dried leaves may be reconstituted and chewed Extracts A concentrated preparation of the leaf, called Salvia extract, is often used in place of natural strength leaves Extract is classified as 5x, 10x, 15x, 20x, etc. Extract reduces the total amount needed to produce results and the results are often more powerful Effects of Salvia The effects seem to span a large spectrum and may be somewhat dependant on amount ingested, method of ingestion, and individual body chemistry Range seems to go from a pleasant, dreamlike experience to a very frightening and confusing experience Low Dose Spontaneous Laughter Mild closed-eye visuals Stuttering or strobing visual effects Changes in depth perception Heightened senses of color and texture Moderate Dose Trance-like state Time distortion Open-eye visuals Fractal patterns and geometric shapes with eyes open Sensations of falling Fully formed visions of other places, people, and events High Dose Out of body experiences Dimensional Distortion Intense exhilaration or panic Sensation of wind or physical pressure Hearing voices Significant open and closed eye visuals Experiencing alternate realities Dissociation Loss of speech Merging with objects High Dose Users have reported feeling as if they have lived a lifetime as another person or as an inanimate object (experiencing a lifetime as paint on a wall for example) This is may be due to the significant time distortion that the drug causes Salvia divinorum Duration Smoked Total Duration 20 - 45 mins Onset 20 - 60 secs Coming Up 1 - 2 mins Plateau 5 - 10 mins Coming Down 15 - 30 mins After Effects 15 - 20 mins Hangover / Day After --- Marketing Often marketed to teens and young adults as producing a marijuana-like high Also sold as a “Legal Cannabis Substitute” In reality, not similar to marijuana at all Not really even a “Party Drug” Legality Colorado has a current law prohibiting manufacture and sale (July 1, 2011) – possession and use illegal Jan 1, 2012 Federal Govt. is studying the plant for scheduling U.S. Military has made it illegal Is able to be tested for in UA Driving on Salvia Synthetic Cannabinoids Spice?? Spice Spice K 2 / Spice – real or hype? Very Real – Spice is a synthetic cannabinoid that acts very similarly to THC Binds to the same receptor sites as cannabis May be anywhere from 3x – 800x the potency of THC Federal Legality The Federal Analog Act defines an analog as: a chemical that is structurally or pharmacologically similar to a Schedule I or II controlled substance and has no legitimate medical use. A substance which meets (this)definition…and is intended for human consumption is treated…as if it were a controlled substance in Schedule I. So how has it been legal? Origins 1995 – Dr. John Hoffman, professor of Organic Chemistry at Clemson University Conducting research on effects of cannabinoids on the brain Developed synthetic cannabinoid (JWH-018) for use in the research Published paper contained info on the chemical used Progression Enterprising individuals replicated the compound JWH-018 and began spraying it on dried flowers, herbs, and tobacco JWH-018 is now the most common synthetic cannabinoid found in Spice blends Progression Spice begins sales around 2006 Other unique, well designed synthetics have spun off of the original design Others include JWH-73, CP-47,497 and HU-210 (there are literally hundreds more) Spice Ingredients - Label Baybean, Blue Lotus, Lion's Tail, Lousewort, Mugwort, Indian Warrior, Dwarf Skullcap, Maconha Brava, Sassafrass, Pink Lotus, Marshmallow, Red Clover, Nutmeg, Rose, Siberian Motherwort, Damiana, Canavalia Maritime, Leonotis Leonurus, Leonurus Sibiricus, Passion Flower, Vanilla Planifolia, Zorinia Latifolia, Magnolia Officinalis, Sage, Rosa Gallica, Trifolium Spice Ingredients - Actual May contain none, some, most, or all of the listed ingredients Will also contain a synthetic or combination of synthetics sprayed onto the mixture Physical Properties Looks like mixture of plant matter Little to no chemical smell – any odor would be due to dried plants (potpourri smell) Effects of the Drug Users report experiences similar to cannabis with possibility of hallucinations In mice it has lead to lower body temp, partial paralysis, and temporary inability to feel pain May also cause seizures, anxiety, agitation, and dangerously increased blood pressure and heart rates Effects Little known regarding detailed pharmacology and toxicology Few formal, human studies published Potential for longer than normal psychoactive effects due to longer halflives of chemicals and full binding at receptor site vs partial binding of THC Variability The variability of substances present from batch to batch helps to make it virtually impossible to test for No “standard” substances and amounts Testing There are a few labs that can test for a few of the synthetics Makes this appealing to probationers, military, people in treatment facilities – anyone needing a clean UA Getting it Typically Spice is sold over the internet and in “head shops”. May also be found at convenience stores, truck stops, and smoke shops Pricing Usually $20 - $60 (1 – 3 grams) Due to potency, can last awhile Hookah? Encounters from customers at Hookah bars suggest K 2 / Spice and/or Salvia are being smoked at Hookah bars Widespread use Current Legality 26 of the synthetic cannabinoids placed in DEA Schedule I As of July 1, Colorado has made manufacture and sale illegal. Jan 1, 2012 possession and use are illegal US Military has banned possession, use Banned in Chile, France, Germany, S. Korea, Sweden, Switzerland, and others Manufacturers Response Within weeks of state bans, new varieties of the drug which skirt the legal issues are on the market K2 Sex Incense. In Compliance with Kansas Laws. Available in 3, 10, 50 gram packages The High 1/10 gram put into a bong (usually) 3-6 hits Quick onset Feels like MJ, but user may experience hallucinations 6 – 8 hour high, some feel effect for 24 hrs Addiction / Withdrawal There are numerous reports of addiction to Spice Also reports of withdrawal and OD deaths from it Withdrawal symptoms include: night sweats, internal unrest, tremors, palpitations, insomnia, headaches, diarrhea, nausea, and vomitting Synthetic Stimulants “Bath Salts” Believed to be synthesized from Cathinone Chemicals are Mephedrone and/or MDPV On par with cocaine May also be marketed as insect repellant or stain removers Bath Salts Bath Salt Reports Users relate experiences similar to cocaine and methamphetamine Some state that the experience is better than cocaine May be snorted, injected, or smoked Effects on the body As with Spice, not much known regarding long term effects since the drug is relatively new Always possibility of addiction Use may cause hyperthermia, increased heart rate and blood pressure, paranoia, agitation, dizziness, vomiting, coma, and death “Smiles” (disclaimer necessary) 2C-I or possibly 25I-NBOMe (2C-I-NBOMe) Effects seem to combine MDMA with LSD Some stimulant effects with intense, prolonged hallucinations Unable to be tested for with standard testing procedures 2C-I Schedule I 2C-I-Nbome not scheduled 2C-I or “Smiles” Due to lack of testing, OD may be overlooked in ER’s Known to cause seizures, muscular rigidity, increase temperature, kidney failure, and fatally high blood pressure Not uncommon for OD’s to result in death 2C-I or “Smiles” Comes in powder, liquid, and pill Ingested orally, sublingually, insufflated Relatively easy to make May be cooked into edibles Potentially active at sub-milligram doses New sister drugs already being seen – 25b-Nbome Outlook Synthetic variants of known drugs are becoming a rapidly growing trend Synthetics have the potential to be more potent than the parent thereby increasing appeal May cause greater changes to brain chemistry and lead to higher incidents of psychological disorders On the horizon? Krokodil (Crocodile) Very cheap heroin substitute Used extensively in Russia “How to make it” guides on the internet What is it? Krokodil Mixture of Codeine, gasoline, paint thinner, iodine, hydrochloric acid and red phosphorus After cooking, users inject the substance intravenously Name comes from the green, scaly appearance that users skin takes on Effects / Consequences Effects very similar to heroin but high is shorter lived Use causes skin to literally rot away Life expectancy of an addict is 1 yr or less Rehab possible but longer and tougher than rehab from heroin Krokodil in the U.S. As of now, no known cases of use in the U.S. It is possible that we will see it – cheaper and possibly easier to get than heroin One to watch for * Disclaimer * The following pictures / videos are very graphic. Please do not feel that you have to view them if you are uncomfortable with graphic, gross, and generally icky stuff. Contact Info Sgt. Craig Simpson Colorado Springs Police Dept craigsimpson5@gmail.com Sources www.erowid.com http://www.emcdda.europa.eu/publications/drug-profiles/syntheticcannabinoids http://www.k2-incense.com/buyktwo/international.php http://www.msnbc.msn.com/id/35444158 http://www.livescience.com/health/fake-marijuana-k2hallucinations-100303.html http://www.usatoday.com/news/nation/2010-05-24-k2_N.htm http://www.arkansasonline.com/news/2010/jul/02/health-boardoks-emergency-ban-k2/ http://www.areawidenews.com/story/1649977.html http://www.desmoinesregister.com/article/20100721/NEWS/721036 6/Pharmacy-board-bans-K2-synthetic-marijuana Colorado Springs Independent – July 22-28, 2010 “Incense Nonsense”