BME/PHYSIOLOGY 419/519 QUANTITATIVE PHYSIOLOGY Fall Semester, 2013 Course Description: Quantitative Physiology provides learning opportunities for advanced undergraduate and graduate students to understand and develop competencies in a quantitative, research oriented, systems approach to physiology. Systems examined include cellular, musculoskeletal, cardiovascular, respiratory, neurologic and reproductive. Mathematical models and engineering analyses are used to describe system performance where applicable. Lectures and problem sessions are used for instruction, and performance is based on homework problem sets and examinations. Class Schedule: BME 419: BME/Physiol 519: Lec Lec M, W M, W 1:30 – 3:30 1504 GG Brown 1:30 – 3:30 1504 GG Brown Class Website: ctools.umich.edu Course Director: James B. Grotberg, Ph.D., M.D. 2123 Gerstacker Bldg 734-936-3834 grotberg@umich.edu Faculty: Susan Brooks (muscle), James Grotberg (respiration), Ian Moench (cells and subcellular), Ariella Shikanov (reproduction), Margaret Westfall (cardiac), David Li (vascular), Ken Kozloff (orthopedic), Andrea Alford (orthopedic), and Tim Bruns (neural) Textbook: Vander’s Human Physiology: The Mechanisms of Body Function, 13th Edition; Widmaier, Raff, Strang; McGraw-Hill. GSI: Robinson Seda Office Hours: TBA robseda@umich.edu Schedule: Date Day Time Topic Lecturer Background Week 1 09/04/13 Wednesday 1:30-3:30 Cells Moench Monday Wednesday 1:30-3:30 1:30-3:30 4:00-6:00 HW 1 Assigned Moench Moench Monday 1:30-3:30 Li Wednesday 1:30-3:30 Vascular HW 1 Due HW 2 Assigned Monday 1:30-3:30 4:00-6:00 1:30-3:30 HW 1 Returned Li Office Hours Cardiac HW 2 Due Li HW 3 Assigned HW 2 Returned Review: Cell, Vascular, Cardiac Westfall Office Hours HW 3 Due (Location TBD) Westfall Westfall Moench, Li, Westfall Friday 1:30-3:30 1:30-2:30 2:30-3:30 4:00-6:00 5:00 PM Week 6 10/07/13 10/09/13 Monday Wednesday 1:30-3:30 1:30-3:30 Respiratory Exam 1: Cell, Vascular, Cardiac HW 3 Returned Grotberg Week 7 10/14/13 10/16/13 Monday Wednesday 1:30-3:30 Week 8 10/21/13 Monday General Book Chapter 1, 2 3,4,5,6 Week 2 09/09/13 09/11/13 Week 3 09/16/13 09/18/13 Week 4 09/23/13 09/25/13 Wednesday Week 5 09/30/13 10/02/13 Monday Wednesday 10/04/13 10/23/13 Wednesday 1:30-3:30 4:00-6:00 1:30-3:30 Moench Office Hours Fall Break No Class Exam 1 Returned HW 4 Assigned 12 Li Westfall 12 12 Grotberg Grotberg Grotberg Office Hours Orthopedics HW 4 Due (Location TBD) Kozloff ---- Week 9 10/28/13 10/30/13 Week 10 11/04/13 11/06/13 Week 11 11/11/13 11/12/13 11/13/13 Week 12 11/18/13 11/20/13 Week 13 11/25/13 11/27/13 1:30-3:30 1:30-2:30 4:00-6:00 2:30-3:30 HW 5 Assigned HW 4 Returned Kozloff Office Hours Muscle Alford Kozloff Monday 1:30-3:30 HW 5 Due HW 6 Assigned Brooks Wednesday 1:30-3:30 Monday Tuesday Wednesday 1:30-2:30 2:30-3:30 4:00-6:00 12:00 PM 1:30-3:30 Monday 1:30-3:30 Wednesday 1:30-3:30 Monday 1:30-3:30 4:00-6:00 1:30-3:30 Monday Wednesday Wednesday Brooks Brooks Review: Resp, Orth., Muscle Brooks Office Hours HW 6 Due (Location TBD) Exam 2: Resp., Orth., Muscle Neurophysiology HW 6 Returned Exam 2 Returned HW 7 Assigned Brooks Grotberg, Kozloff, Brooks Bruns Bruns Bruns Chestek Office Hours Reproductive Physiology HW 7 Due Shikanov Thanksgiving Recess Week 14 12/02/13 12/04/13 12/06/13 Week 15 12/09/13 Friday 1:30-3:30 1:30-2:30 2:30-3:30 4:00-6:00 5:00 PM HW 8 Assigned HW 7 Returned Review: Neur, Reprod Shikanov Office Hours HW 8 Due (Location TBD) Monday 6:00-8:00 Exam 3: Neuro + Reprod Monday Wednesday 9,10 Shikanov Shikanov Bruns, Shikanov 6,7,8 Note: Homework assignments are either due by the end of class (if class is held on the due date) or the times listed above. Solutions will be posted once the assignments are collected; HENCE NO LATE HOMEWORKS WILL BE ACCEPTED! Course grading: Exam 1 Exam 2 Exam 3 Home Works 25% 25% 20% 30%