PUBLICATIONS – 2006 The use of HAART for biological tumour therapy. Monini P, Toschi E, Sgadari C, Bacigalupo I, Palladino C, Carlei D, Barillari G, Ensoli B. J HIV Ther. 2006; 11(3):53-6. Solvent/detergent plasma for prevention of bleeding in recessively inherited coagulation disorders: dosing, pharmacokinetics and clinical efficacy. Santagostino E, Mancuso ME, Morfini M, Schiavoni M, Tagliaferri A, Barillari G, Mannucci PM. Haematologica. 2006; 91(5):634-9. HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway. Toschi E, Bacigalupo I, Strippoli R, Chiozzini C, Cereseto A, Falchi M, Nappi F, Sgadari C, Barillari G, Mainiero F, Ensoli B. Mol Biol Cell. 2006; 17(4):1985-94. Effects of a natural extract from Mangifera indica L, and its active compound, mangiferin, on energy state and lipid peroxidation of red blood cells. Rodríguez J, Di Pierro D, Gioia M, Monaco S, Delgado R, Coletta M, Marini S. Biochim Biophys Acta. 2006; 1760(9):1333-42. Human dendritic cells following Aspergillus fumigatus infection express the CCR7 receptor and a differential pattern of interleukin-12 (IL-12), IL-23, and IL-27 cytokines, which lead to a Th1 response. Gafa V, Lande R, Gagliardi MC, Severa M, Giacomini E, Remoli ME, Nisini R, Ramoni C, Di Francesco P, Aldebert D, Grillot R, Coccia EM. Infect Immun. 2006; 74(3):1480-9. A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model. Niola F, Evangelisti C, Campagnolo L, Massalini S, Buè MC, Mangiola A, Masotti A, Maira G, Farace MG, Ciafrè SA. Cancer Biol Ther. 2006;5(2):174-9. Feasibilty of in utero DNA vaccination following naked gene transfer into pig fetal muscle: transgene expression, immunity and safety. Rinaldi M, Signori E, Rosati P, Cannelli G, Parrella P, Iannace E, Monego G, Ciafrè SA, Farace MG, Iurescia S, Fioretti D, Rasi G, Fazio VM. Vaccine. 2006; 24(21):4586-91. Apoptotic cell signaling in lymphocytes from HIV+ patients during successful therapy. Grelli S, Balestrieri E, Matteucci C, Minutolo A, D'Ettorre G, Lauria F, Montella F, Vullo V, Vella S, Favalli C, Mastino A, Macchi B. Ann N Y Acad Sci. 2006; 090:130-7. Comparison of DNA sequencing and Roche Linear array in human papillomavirus (HPV) genotyping. Giuliani L, Coletti A, Syrjänen K, Favalli C, Ciotti M. Anticancer Res. 2006; 26(5B):3939-41. The p53 codon 72 arg/arg homozygous women in central Italy are at increased risk for HPV infections. Ciotti M, Coletti A, Giuliani L, Cappiello G, Syrjanen K, Favalli C. Anticancer Res. 2006; 26(5B):3745-8. Upregulation of telomerase (hTERT) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus, virus persistence, or disease outcome in cervical cancer. Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Ruutu M, Syrjänen S, Favalli C, Syrjänen K. Diagn Cytopathol. 2006; 34(11):739-48. Over-expression of topoisomerase IIalpha is related to the grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment. Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Ruutu M, Syrjänen SM, Favalli C, Syrjänen K; HPV-PathogenISS Study Group. Int J Gynecol Pathol. 2006; 25(4):383-92. Entire genome of a strain of human immunodeficiency virus type 1 with a deletion of nef that was recovered 20 years after primary infection: large pool of proviruses with deletions of env. Calugi G, Montella F, Favalli C, Benedetto A. J Virol. 2006; 80(23):11892-6. Upregulation of nuclear factor-kappaB (NF-kappaB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer. Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Ruutu M, Syrjänen S, Favalli C, Syrjänen K; HPVPthogen ISS Study Group. Diagn Cytopathol. 2006; 34(8):555-63. Down-regulation of E-cadherin is closely associated with progression of cervical intraepithelial neoplasia (CIN), but not with high-risk human papillomavirus (HPV) or disease outcome in cervical cancer. Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Syrjänen S, Favalli C, Syrjänen K; HPVPathogenISS Study Group. Eur J Gynaecol Oncol. 2006; 27(3):215-23. Detection and expression of human papillomavirus oncogenes in non-small cell lung cancer. Ciotti M, Giuliani L, Ambrogi V, Ronci C, Benedetto A, Mineo TC, Syrjänen K, Favalli C. Oncol Rep. 2006; 16(1):183-9. Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN. Branca M, Ciotti M, Giorgi C, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Syrjänen S, Favalli C, Syrjänen K; HPV-PathogenISS Study Group. Anticancer Res. 2006; 26(2B):1543-56. Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to highrisk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer. Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Ruutu M, Favalli C, Syrjänen K; HPV-Pathogen Istituto Superiore di Sanità Study Group. J Clin Pathol. 2006; 59(10):1044-51. Relationship of up-regulation of 67-kd laminin receptor to grade of cervical intraepithelial neoplasia and to high-risk HPV types and prognosis in cervical cancer. Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Syrjänen S, Favalli C, Syrjänen K; HPVPathogenISS Study Group. Acta Cytol. 2006; 50(1):6-15. Aberrant expression of VEGF-C is related to grade of cervical intraepithelial neoplasia (CIN) and high risk HPV, but does not predict virus clearance after treatment of CIN or prognosis of cervical cancer. Branca M, Giorgi C, Santini D, Di Bonito L, Ciotti M, Benedetto A, Paba P, Costa S, Bonifacio D, Di Bonito P, Accardi L, Favalli C, Syrjänen K; HPV-Pathogen ISS Study Group. J Clin Pathol. 2006; 59(1):40-7. Single or multiple HPV types in cervical cancer and associated metastases. Ciotti M, Paba P, Bonifacio D, Di Bonito L, Benedetto A, Favalli C. Oncol Rep. 2006; 15(1):143-8. Cellular and biochemical parameters of exercise-induced oxidative stress: relationship with training levels. Pittaluga M, Parisi P, Sabatini S, Ceci R, Caporossi D, Valeria Catani M, Savini I, Avigliano L. Free Radic Res. 2006; 40(6):607-14 Properties of copper-free pig kidney amine oxidase: role of TOPA quinone. Mura A, Padiglia, A, Medda, Pintus R, Finazzi Agrò A, Floris G. FEBS Lett. 2006; 580(18):4317-4324. Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells. Maccarrone M, Fiori A, Bari M, Granata F, Gasperi V, De Stefano ME, Finazzi Agrò A, Strom R. Thromb Haemost. 2006; 95: 117-127 Closing the gate to the active site: Effect of the inhibitor MAFP on the conformation and membrane binding of fatty acid amide hydrolase. Mei G, Di Venere A, Gasperi V, Nicolai E, Masuda KR, Finazzi Agrò A, Cravatt BF, Maccarrone M. J Biol Chem 2007;282(6):3829-36. Physico-chemical properties of molten dimer ascorbate oxidase. Nicolai E, Di Venere A, Rosato N, Rossi A, Finazzi Agro' A., Mei G FEBS Journal. 2006: 273: 5194-5204. The endocannabinoid system in neurodegeneration. Battista N, Fezza F, Finazzi-Agro A, Maccarrone M. Ital J Biochem. 2006; 55(3-4) 283-9. Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. Bari M, Spagnuolo P, Fezza F, Oddi S, Pasquariello N, Finazzi-Agro A, Maccarrone M. J Immunol. 2006; 177(8): 4971-80. Candidate HIV-1 Tat vaccine development: from basic science to clinical trials. Ensoli B, Fiorelli V, Ensoli F, Cafaro A, Titti F, Buttò S, Monini P, Magnani M, Caputo A, Garaci E. AIDS. 2006;;20(18):2245-61. Antiviral and immunomodulatory properties of new pro-glutathione (GSH) molecules. Fraternale A, Paoletti MF, Casabianca A, Oiry J, Clayette P, Vogel JU, Cinatl J Jr, Palamara AT, Sgarbanti R, Garaci E, Millo E, Benatti U, Magnani M. Curr Med Chem. 2006; 13(15):1749-55. Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance. Romani L, Bistoni F, Perruccio K, Montagnoli C, Gaziano R, Bozza S, Bonifazi P, Bistoni G, Rasi G, Velardi A, Fallarino F, Garaci E, Puccetti P. Blood. 2006; 108(7):2265-74. Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences. De Chiara G, Marcocci ME, Torcia M, Lucibello M, Rosini P, Bonini P, Higashimoto Y, Damonte G, Armirotti A, Amodei S, Palamara AT, Russo T, Garaci E, Cozzolino F. J Biol Chem. 2006; 281(30):21353-61. Rhinoviruses promote internalisation of Staphylococcus aureus into non-fully permissive cultured pneumocytes. Passariello C, Schippa S, Conti C, Russo P, Poggiali F, Garaci E, Palamara AT. Microbes Infect. 2006;8(3):758-66. A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy. Sinibaldi-Vallebona P, Lavia P, Garaci E, Spadafora C. Genes Chromosomes Cancer. 2006; 45(1):1-10. A cytoplasmic PML mutant inhibits p53 function. Bellodi C, Kindle K, Bernassola F, Cossarizza A, Dinsdale D, Melino G, Heery D, Salomoni P. Cell Cycle. 2006; 5(22):2688-92. p63 is upstream of IKK alpha in epidermal development. Candi E, Terrinoni A, Rufini A, Chikh A, Lena AM, Suzuki Y, Sayan BS, Knight RA, Melino G. J Cell Sci. 2006; 119(Pt 22):4617-22. TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones. Hooper C, Tavassoli M, Chapple JP, Uwanogho D, Goodyear R, Melino G, Lovestone S, Killick R. J Neurochem. 2006; 99(3):989-99. New p63 targets in keratinocytes identified by a genome-wide approach. Viganò MA, Lamartine J, Testoni B, Merico D, Alotto D, Castagnoli C, Robert A, Candi E, Melino G, Gidrol X, Mantovani R. EMBO J. 2006; 25(21):5105-16. FLASH is an essential component of Cajal bodies. Barcaroli D, Dinsdale D, Neale MH, Bongiorno-Borbone L, Ranalli M, Munarriz E, Sayan AE, McWilliam JM, Smith TM, Fava E, Knight RA, Melino G, De Laurenzi V. Proc Natl Acad Sci U S A. 2006 ; 103(40):14802-7. FLASH is required for histone transcription and S-phase progression. Barcaroli D, Bongiorno-Borbone L, Terrinoni A, Hofmann TG, Rossi M, Knight RA, Matera AG, Melino G, De Laurenzi V. Proc Natl Acad Sci U S A. 2006; 103(40):14808-12. "Tissue" transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes. Mastroberardino PG, Farrace MG, Viti I, Pavone F, Fimia GM, Melino G, Rodolfo C, Piacentini M. Biochim Biophys Acta. 2006; 1757(9-10):1357-65. p63 and p73, members of the p53 gene family, transactivate PKCdelta. Ponassi R, Terrinoni A, Chikh A, Rufini A, Lena AM, Sayan BS, Melino G, Candi E. Biochem Pharmacol. 2006; 72(11):1417-22. Degradation of p63 by Itch. Melino G, Knight RA, Cesareni G. Cell Cycle. 2006; 5(16):1735-9. The E3 ubiquitin ligase Itch controls the protein stability of p63. Rossi M, Aqeilan RI, Neale M, Candi E, Salomoni P, Knight RA, Croce CM, Melino G. Proc Natl Acad Sci U S A. 2006; 103(34):12753-8. NMR structure of the p63 SAM domain and dynamical properties of G534V and T537P pathological mutants, identified in the AEC syndrome. Cicero DO, Falconi M, Candi E, Mele S, Cadot B, Di Venere A, Rufini S, Melino G, Desideri A. Cell Biochem Biophys. 2006; 44(3):475-89. Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice. Candi E, Rufini A, Terrinoni A, Dinsdale D, Ranalli M, Paradisi A, De Laurenzi V, Spagnoli LG, Catani MV, Ramadan S, Knight RA, Melino G. Cell Death Differ. 2006; 13(6):1037-47. TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism. Hooper C, Killick R, Tavassoli M, Melino G, Lovestone S. Neurosci Lett. 2006; 401(1-2):30-4. Cytoplasmic function of mutant promyelocytic leukemia (PML) and PML-retinoic acid receptor-alpha. Bellodi C, Kindle K, Bernassola F, Dinsdale D, Cossarizza A, Melino G, Heery D, Salomoni P. J Biol Chem. 2006; 281(20):14465-73. p53 is cleaved by caspases generating fragments localizing to mitochondria. Sayan BS, Sayan AE, Knight RA, Melino G, Cohen GM. J Biol Chem. 2006; 281(19):13566-73. Tissue transglutaminase (TG2) protects cardiomyocytes against ischemia/reperfusion injury by regulating ATP synthesis. Szondy Z, Mastroberardino PG, Váradi J, Farrace MG, Nagy N, Bak I, Viti I, Wieckowski MR, Melino G, Rizzuto R, Tósaki A, Fesus L, Piacentini M. Cell Death Differ. 2006; 13(10):1827-9. Matrix changes induced by transglutaminase 2 lead to inhibition of angiogenesis and tumor growth. Jones RA, Kotsakis P, Johnson TS, Chau DY, Ali S, Melino G, Griffin M. Cell Death Differ. 2006; 13(9):1442-53. Alpha-linolenic acid-enriched diet prevents myocardial damage and expands longevity in cardiomyopathic hamsters. Fiaccavento R, Carotenuto F, Minieri M, Masuelli L, Vecchini A, Bei R, Modesti A, Binaglia L, Fusco A, Bertoli A, Forte G, Carosella L, Di Nardo P. Am J Pathol. 2006; 169(6):1913-24. Immunity to extracellular matrix antigens is associated with ultrastructural alterations of the stroma and stratified epithelium basement membrane in the skin of Hashimotos thyroiditis patients. Bei R, Mentuccia D, Trono P, Trono P, Masuelli L, Cereda V, Palumbo C, Marzocchella L, Mrozek MA, Pallotta P, Di Lella G, Modesti M, Cerilli M, Frajese GV, Frajese G, Zambruno G, Modesti A. Int J Immunopathol Pharmacol. 2006; 19(3):661-74. Extremely low frequency electromagnetic field exposure promotes differentiation of pituitary corticotrope-derived AtT20 D16V cells. Lisi A, Ledda M, Rosola E, Pozzi D, D'Emilia E, Giuliani L, Foletti A, Modesti A, Morris SJ, Grimaldi S. Bioelectromagnetics. 2006;27(8):641-51. Overexpression of ErbB2 and ErbB3 receptors in Schwann cells of patients with CharcotMarie-tooth disease type 1A. Massa R, Palumbo C, Cavallaro T, Panico MB, Bei R, Terracciano C, Rizzuto N, Bernardi G, Modesti A. Muscle Nerve. 2006; 33(3):342-9. Does residual virus replication during successful HAART lead to HIV-1 genetic evolution? Aquaro S, Svicher V, Perno CF. J HIV Ther. 2006; 11(4):84-8. Novel drug resistance mutations in HIV: recognition and clinical relevance. Perno CF, Svicher V, Ceccherini-Silberstein F. AIDS Rev. 2006;8(4):179-90. Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak. de Oliveira T, Pybus OG, Rambaut A, Salemi M, Cassol S, Ciccozzi M, Rezza G, Gattinara GC, D'Arrigo R, Amicosante M, Perrin L, Colizzi V, Perno CF; Benghazi Study Group. Nature. 2006; 444(7121):836-7. Respiratory viruses and influenza-like illness: a survey in the area of Rome, winter 20042005. Rezza G, Valdarchi C, Puzelli S, Ciotti M, Farchi F, Fabiani C, Calzoletti L, Donatelli I, Perno CF. Euro Surveill. 2006; 11(10):251-3. Administration of fludarabine-loaded autologous red blood cells in simian immunodeficiency virus-infected sooty mangabeys depletes pSTAT-1-expressing macrophages and delays the rebound of viremia after suspension of antiretroviral therapy. Cervasi B, Paiardini M, Serafini S, Fraternale A, Menotta M, Engram J, Lawson B, Staprans SI, Piedimonte G, Perno CF, Silvestri G, Magnani M. J Virol. 2006; 80(21):10335-45. Drug-class-wide resistance to antiretrovirals in HIV-infected patients failing therapy: prevalence, risk factors and virological outcome. Tozzi V, Zaccarelli M, Bonfigli S, Lorenzini P, Liuzzi G, Trotta MP, Forbici F, Gori C, Bertoli A, Bellagamba R, Narciso P, Perno CF, Antinori A; Collaborative Group for Clinical Use of HIV Genotype Resistance Test. Antivir Ther. 2006;11(5):553-60. Safety of nevirapine-containing antiretroviral triple therapy regimens to prevent vertical transmission in an African cohort of HIV-1-infected pregnant women. Marazzi MC, Germano P, Liotta G, Guidotti G, Loureiro S, da Cruz Gomes A, Valls Blazquez MC, Narciso P, Perno CF, Mancinelli S, Palombi L. HIV Med. 2006; 7(5):338-44. Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirs. Montaner LJ, Crowe SM, Aquaro S, Perno CF, Stevenson M, Collman RG. J Leukoc Biol. 2006; 80(5):961-4. Comparative analysis of T-cell turnover and homeostatic parameters in HIV-infected patients with discordant immune-virological responses to HAART. Marchetti G, Gori A, Casabianca A, Magnani M, Franzetti F, Clerici M, Perno CF, Monforte A, Galli M, Meroni L. AIDS. 2006; 20(13):1727-36. Mechanisms underlying activity of antiretroviral drugs in HIV-1-infected macrophages: new therapeutic strategies. Aquaro S, Svicher V, Schols D, Pollicita M, Antinori A, Balzarini J, Perno CF. J Leukoc Biol. 2006; 80(5):1103-10. Specific mutations in HIV-1 gp41 are associated with immunological success in HIV-1infected patients receiving enfuvirtide treatment. Aquaro S, D'Arrigo R, Svicher V, Perri GD, Caputo SL, Visco-Comandini U, Santoro M, Bertoli A, Mazzotta F, Bonora S, Tozzi V, Bellagamba R, Zaccarelli M, Narciso P, Antinori A, Perno CF. J Antimicrob Chemother. 2006; 58(4):714-22. Temporal characterization of drug resistance associated mutations in HIV-1 protease and reverse transcriptase in patients failing antiretroviral therapy. Santoro MM, Svicher V, Gori C, Zaccarelli M, Tozzi V, Forbici F, D'Arrigo R, Trotta MP, Bellocchi MC, Visco-Comandini U, Cenci A, Bertoli A, Narciso P, Antinori A, Perno CF, Ceccherini-Silberstein F. New Microbiol. 2006; 29(2):89-100. Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors. Svicher V, Sing T, Santoro MM, Forbici F, Rodríguez-Barrios F, Bertoli A, Beerenwinkel N, Bellocchi MC, Gago F, d'Arminio Monforte A, Antinori A, Lengauer T, CeccheriniSilberstein F, Perno CF. J Virol. 2006; 80(14):7186-98. Therapeutic strategies towards HIV-1 infection in macrophages. Perno CF, Svicher V, Schols D, Pollicita M, Balzarini J, Aquaro S. Antiviral Res. 2006; 71(2-3):293-300. p63 protein is essential for the embryonic development of vibrissae and teeth. Rufini A, Weil M, McKeon F, Barlattani A, Melino G, Candi E. Biochem Biophys Res Commun. 2006; 340(3):737-41. Highly active antiretroviral therapy reduces the age-associated risk of dementia in a cohort of older HIV-1-infected patients. Larussa D, Lorenzini P, Cingolani A, Bossolasco S, Grisetti S, Bongiovanni M, Moretti F, Uccella I, Zannoni P, Foresti S, Mazzarello G, Arcidiacono MI, Pedale R, Ammassari A, Tozzi V, Perno CF, Monforte AD, Cinque P, Antinori A; Italian Registry Investigative Neuro AIDS (IRINA). AIDS Res Hum Retroviruses. 2006; 22(5):386-92. Antiviral efficacy and genotypic resistance patterns of combination therapy with stavudine/tenofovir in highly active antiretroviral therapy experienced patients. Antinori A, Trotta MP, Nasta P, Bini T, Bonora S, Castagna A, Zaccarelli M, Quirino T, Landonio S, Merli S, Tozzi V, Di Perri G, Andreoni M, Perno CF, Carosi G. Antivir Ther. 2006; 11(2):233-43. Key questions in antiretroviral therapy: Italian Consensus Workshop (2005). Carosi G, Torti C, Andreoni M, Angarano G, Antinori A, Bonora S, Borderi M, Castagna A, Castelli F, Cauda R, Chiodo F, D'arminio-Monforte A, De Luca A, Di Perri G, Dianzani F, Filice G, Galli M, Lazzarin A, Maggiolo F, Maserati R, Mazzotta F, Moroni M, Perno CF, Vullo V. J Antimicrob Chemother. 2006; 57(6):1055-64. A killer mimotope with therapeutic activity against AIDS-related opportunistic microorganisms inhibits ex-vivo HIV-1 replication. Casoli C, Pilotti E, Perno CF, Balestra E, Polverini E, Cassone A, Conti S, Magliani W, Polonelli L. AIDS. 2006; 20(7):975-80. Improving adherence to highly active anti-retroviral therapy in Africa: the DREAM programme in Mozambique. Marazzi MC, Bartolo M, Emberti Gialloreti L, Germano P, Guidotti G, Liotta G, Magnano San Lio M, Mancinelli S, Modolo MA, Narciso P, Perno CF, Scarcella P, Tintisona G, Palombi L. Health Educ Res. 2006; 21(1):34-42. Adsorption of streptavidin onto single-walled carbon nanotubes: application in fluorescent supramolecular nanoassemblies. Bottini M, Cerignoli F, Tautz L, Rosato N, Bergamaschi A, Mustelin T. J Nanosci Nanotechnol. 2006; 6(12):3693-8. Physico-chemical properties of molten dimer ascorbate oxidase. Nicolai E, Di Venere A, Rosato N, Rossi A, Finazzi Agro' A, Mei G. FEBS J. 2006; 273(22):5194-204. The interaction of the polyphenylacetylene surface with biological environments studied by XPS, RAIRS and biological tests. Iucci G, Rossi L, Rosato N, Savini I, Duranti G, Polzonetti G. J Mater Sci Mater Med. 2006; 17(9):779-87. Full-length single-walled carbon nanotubes decorated with streptavidin-conjugated quantum dots as multivalent intracellular fluorescent nanoprobes. Bottini M, Cerignoli F, Dawson MI, Magrini A, Rosato N, Mustelin T. Biomacromolecules. 2006; 7(8):2259-63. Dispersion of pristine single-walled carbon nanotubes in water by a thiolated organosilane: application in supramolecular nanoassemblies. Bottini M, Magrini A, Rosato N, Bergamaschi A, Mustelin T. J Phys Chem B. 2006; 110(28):13685-8. Synthesis and characterization of supramolecular nanostructures of carbon nanotubes and ruthenium-complex Luminophores. Bottini M, Magrini A, Di Venere A, Bellucci S, Dawson MI, Rosato N, Bergamaschi A, Mustelin T. J Nanosci Nanotechnol. 2006; 6(5):1381-6. Long-lived C. elegans mitochondrial mutants as a model for human mitochondrialassociated diseases. Ventura N, Rea SL, Testi R. Exp Gerontol. 2006 ;41(10):974-91. 5-aminosalicylic acid enhances anchorage-independent colorectal cancer cell death. Fina D, Franchi L, Caruso R, Peluso I, Naccari GC, Bellinvia S, Testi R, Pallone F, Monteleone G. Eur J Cancer. 2006; 42(15):2609-16. C. elegans as a model for Friedreich Ataxia. Ventura N, Rea SL, Handerson ST, Condò I, Testi R, Johnson TE. FASEB J. 2006;20(7):1029-30. c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization. di Bari MG, Ciuffini L, Mingardi M, Testi R, Soddu S, Barilà D. EMBO Rep. 2006 Jul;7(7):727-33. Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression. Cursi S, Rufini A, Stagni V, Condò I, Matafora V, Bachi A, Bonifazi AP, Coppola L, SupertiFurga G, Testi R, Barilà D. EMBO J. 2006 ;25(9):1895-905. A pool of extramitochondrial frataxin that promotes cell survival. Condò I, Ventura N, Malisan F, Tomassini B, Testi R. J Biol Chem. 2006; 281(24):16750-6. 9-O-acetyl GD3 protects tumor cells from apoptosis. Kniep B, Kniep E, Ozkucur N, Barz S, Bachmann M, Malisan F, Testi R, Rieber EP. Int J Cancer. 2006; 119(1):67-73. Ceramide catabolism critically controls survival of human dendritic cells. Franchi L, Malisan F, Tomassini B, Testi R. J Leukoc Biol. 2006; 79(1):166-72.