Higher task HB2.25.1 Lesson reference: B2.25 The importance of Mendel’s work The importance of Mendel’s work Learning objectives: Know that other scientists rediscovered Mendel’s work and linked his ‘inherited factors’ with chromosomes and genes. Understand that there are different forms of genes, called alleles. Be able to interpret genetic diagrams of monohybrid inheritance. Suggested time: 30 minutes Name: ________________________________ Date: ______________________ Read the following passage and then answer the questions. Gregor Mendel carried out many plant breeding experiments and worked out some laws of heredity. He worked in the garden of his monastery and carried out breeding experiments with pea plants, Pisum sativum. He understood the structure of flowers and that he could remove the anthers of some of the pea flowers before they were mature. This emasculated the flowers, that is, removed their male parts. He could then take pollen from another pea flower and, using a small brush or a feather, place it on the stigma, the female part of a pea flower. Pea plants were particularly useful because they have the following characteristics: There are many distinct varieties of them, with distinct phenotypes. These different varieties belong to the same species and they can be interbred to produce fertile offspring. The flowers normally self-pollinate but can be crossed, as described above. The plants are easy to grow. They have a one-year life cycle so Mendel could collect data relating to many generations. One type of pea plant has flowers all along the stems. This is called axialflowering. Another type of pea plant has flowers only at the ends of stems. This is called terminal-flowering. Other plant breeders had carried out experiments similar to the ones Mendel did, but Mendel was the first to count the different types of offspring and collect numerical data. © Oxford University Press 2011 This document may have been altered from the original. 236 Mendel crossed true-breeding, axial-flowered plants with true-breeding terminalflowered plants. He collected and grew the seeds. All the F1 generation produced plants with axial flowers. He allowed these plants to self-pollinate, and therefore self-fertilise, and collected and grew their seeds. In the F2 generation, there were 858 plants. 657 of them were axial-flowered. A Which characteristic is dominant – axial flowering or terminal flowering? _________________________________________________________________ B In the F2 generation, how many of the offspring have terminal flowers? _________________________________________________________________ C How did Mendel make sure that none of the true-breeding pea parents could self-pollinate? _________________________________________________________________ _________________________________________________________________ D How did Mendel cross pollinate the two types of pea plant? _________________________________________________________________ _________________________________________________________________ E Draw genetic diagrams, using Punnett squares where necessary, to explain the results described above. Show the phenotypes and genotypes of the parents and offspring. Indicate whether individuals are homozygous or heterozygous. © Oxford University Press 2011 This document may have been altered from the original. 237 F As Mendel worked in a monastery garden, where food plants were grown, it may have been luck that he worked with pea plants. What characteristics of pea plants made them very useful for his breeding experiments? _________________________________________________________________ _________________________________________________________________ _________________________________________________________________ _________________________________________________________________ _________________________________________________________________ G Pea plants have 14 chromosomes in each of their body cells. How many chromosomes are there in i a pea male gamete, ii a pea female gamete? i _________________________ ii __________________________ H What type of cell division is used to make pea gametes? _________________________________________________________________ I Although Mendel’s work, which was published in 1866, was not recognised for its great importance at the time, Mendel is now revered amongst biologists and geneticists. Biologists describe characteristics that are determined by a single gene that has two or more alleles as Mendelian. Their inheritance pattern is also described as Mendelian. Some human traits that show simple Mendelian inheritance include ear lobe shape, tongue-rolling, sickle cell disease, cystic fibrosis, and Huntington disease. There are many other traits, such as arthritis, which involve many genes, so they do not show such a simple inheritance pattern. Which type of inheritance pattern could a genetic counsellor most easily explain to a couple expecting a baby? _________________________________________________________________ _________________________________________________________________ © Oxford University Press 2011 This document may have been altered from the original. 238 J In the USA, between 1904 and 1925, a biologist called Thomas Hunt Morgan carried out many genetics experiments. He put forward the idea that genes and chromosomes contain the inheritable material that determines an organism’s characteristics and development. Along with three other biologists, he rediscovered Mendel’s work and realised its significance. He also realised that understanding how genes and chromosomes work gave the support to Darwin’s theory of natural selection needed to explain the phenomenon of evolution. Which one of the following statements do you think is untrue? 1 Mutations cause changes to an organism’s genetic material – genes or chromosomes. 2 Mutations can be passed on to offspring. 3 Some mutations are useful and make an organism better adapted to its environment so it can out-compete other organisms of its species. 4 Evolution is a fact as new species have arisen since life began on Earth. One theory that can explain how this happened is the theory of natural selection, put forward by Charles Darwin. This is the most widely accepted theory as there is a lot of scientific evidence to support it. 5 Scientists cannot be sure that genes and chromosomes are the hereditary material of living organisms. _________________________________________________________________ © Oxford University Press 2011 This document may have been altered from the original. 239