Description of the RERF DS86 Mortality and
Average Organ Transmission Factor Data Files
25 June 1992
This disk contains four files:
CMDS86.R11 -
Life Span Study mortality data for the
period 1950
through 1985.
DS86TF.DAT transmission factors
city- and age-at-exposure-specific
which can be used to compute organ dose
estimates
CMDDS86.DOC -
a copy of this text in ASCII format
CMDDS86.5P1 -
a copy of this text in Word Perfect 5.1
CMDDS86.SCR -
an AMFIT command script used to compute
format
selected
summary statistics and fit some sample
models similar
to those used in LSS Report 11 and BEIR V
CMDDS86.LOG -
the output produced by the CMDDS86.SCR
script
The CMDS86.R11 file contains data on mortality among survivors of
the atomic
bombings of Hiroshima and Nagasaki during the period from October 1, 1950
through
December 31, 1985. The population consists of all members of the
Radiation Effects Research
Foundation (RERF) Life Span Study (LSS) cohort with complete follow-up
for whom DS86 dose
estimates were available in December, 1987. This population is identical
to that used for the
analyses discussed by Preston and Pierce (RERF TR 9-87 and Rad. Res.
114:437-66, 1987) and
in Life Span Study Report 11, Part 1 (RERF TR 12-87 and Rad. Res.
118:502-24, 1989) and
Part 2 (RERF TR 5-88 and Rad. Res. 121:120-41, 1990). These data were
also used in analyses
carried out for the BEIR V report (NAS 1990).
If these data are used as the basis for analyses in any publication
including working
papers or technical reports, a statement of acknowledgement must be
included in the
manuscript.
This statement should read:
This report makes use of data obtained from the Radiation
Effects Research Foundation (RERF) in Hiroshima, Japan.
RERF is a private foundation funded equally by the Japanese
Ministry of Health and Welfare and the U.S. Department of
Energy through the U.S. National Academy of Sciences. The
conclusions in this report are those of the authors and do
not
necessarily reflect the scientific judgement of RERF or its
funding agencies.
Please send a copy of any reprints which make use of these data to:
Administration and Support Section
Publication and Documentation Center
Radiation Effects Research Foundation
5-2 Hijiyama Koen
Minami-ku
Hiroshima Shi 732 JAPAN
The files on this disk are similar to those used in the BEIR V
analyses, but differ
somewhat from the Report 11 data sets. In particular, for the sitespecific analyses in LSS
Report 11 dose-categories were defined in terms of the appropriate
individual organ dose
estimates (i.e.- a separate data set was created for each tumor type).
Also, the data sets used
for the Report 11 analyses were based upon a less detailed stratification
on age-at-exposure
than is used here (the number of records in each Report 11 data set was
about 1600). The
main data set differs from the BEIR V data set in that it includes
information on additional
cancer death categories considered in LSS Report 11 and on specific noncancer causes of death.
The DS86 dose estimates differ slightly from those in the original BEIR V
data set because of
minor changes to DS86 made after the data were given to the committee.
The eight non-cancer
causes included here are the same causes considered in LSS Report 11 part
3 (Shimizu et al
RERF TR 2-91 and Red. Res. 130, 249-66, 1992).
The data in the main file summarize the mortality experience of the
subcohort for the
period from October 1, 1950 through December 31, 1985 for 75,991 members
of the LSS-E85
cohort for whom DS86 dose estimates could be computed in December 1987.
Members of the
cohort not included in this tabulation include 26,517 people who were not
in the cities at the
time of the bomb, 2,384 survivors for whom dose estimates could not be
computed because of
inadequate information on shielding, and 15,237 survivors who had T65DR
dose estimates, but
for whom DS86 estimates could not be computed.
Each record in CMDS86.R11 contains data for a single cell in a crosstabulation over city, sex,
age-at-exposure, total DS86 kerma, and calendar time. For each cell the
data are:
a)
integer indices for city, sex, age-at-exposure, DS86 total
kerma, and calendar
time.
b)
the total number of person-years in the cell
c)
the number of people first-at-risk, i.e. entering follow-up,
in the cell
d)
the total number of deaths from any cause in the cell
e)
person-year weighted mean values for the gamma, neutron, and
total kerma (in
mGy)
f)
person-year weighted mean values for time-since- and age-atexposure (attained
age can be computed as the sum of these two values)
f)
categories
counts of the numbers of deaths in each of 32 non-exclusive
All fields are separated by at least one blank so the file can
easily be read by any
program capable of reading blank delimited ASCII files. The following
FORTRAN formats can
also be used:
(3i3,3x,2i3,f12.2,2f6.0,5f10.2,32f5.0)
or
(3f3.0,3x,2f3.0,f12.2,2f6.0,5f10.2,32f5.0)
The following pages contain additional details on the format of the
data files.
Format of LSS Mortality File
CMDDS86.R11
File Name
#Records
Record Length
#Variables/Record
CMDS86.R11
3399
200
31
File Format:
IBM PC-DOS 3.1
3.5-inch 1.44 MB, or 5.25-inch 1.2 MB
File Size
(Bytes)
686,599
Study Population:DS86 subcohort as defined in RERF Life Span Study Report
11 Parts 1 to 3 and RERF Technical Reports 9-87
Creation Date:
4 December 1987
Revision History:17 December 1991
25 June 1992
Added first at risk count and Noncancer Mortality data
Added Additional sites reordered cases
counts
Cross-classification variables are items 1-5.
Summary variables are items 7-32.
Output
Name
Description
1) City
I3
Cols.
1-3
1 = Hiroshima
2 = Nagasaki
2) Sex
I3
4-6
1 = Male
2 = Female
3) Age at Exposure
I3
(in years)
1 = 0-4
2 = 5-9
3 = 10-14
4 = 15-19
5 = 20-24
6 = 25-29
7 = 30-34
8 = 35-39
9 = 40-44
10 = 45-49
11 = 50-54
7-9
Format
12 = 55-59
13 = 60+
Name
Description
Cols.
4) DS86 Total Kerma (in mGy)
(kerma values take into account shielding
by structures and terrain)
1
2
3
4
5
6
7
8
9
10
=
=
=
=
=
=
=
=
=
=
DS86 Category
Interpretation
(in Gy)
0
0.005 - 0.05
0.06 - 0.09
0.10 - 0.19
0.20 - 0.49
0.50 - 0.99
1.00 - 1.99
2.00 - 2.99
3.00 - 3.99
4.00 - 6.00
Output
Format
13-15
I3
Definition
(in mGy)
0 4
5 54
55 94
95 - 194
195 - 494
495 - 994
995 - 1994
1995 - 2994
2995 - 3994
3995 - 6000
Note: When referring to DS86 dose categories, please use the
labels which are specified above in Gy. As a standard, RERF
creates dose categories by rounding to the nearest 10 mGy.
5) Calendar
1 =
2 =
3 =
4 =
5 =
6 =
7 =
Time
1 Oct
1 Jan
1 Jan
1 Jan
1 Jan
1 Jan
1 Jan
16-18
1950
1956
1961
1966
1971
1976
1981
to
to
to
to
to
to
to
31
31
31
31
31
31
31
Dec
Dec
Dec
Dec
Dec
Dec
Dec
1955
1960
1965
1970
1975
1980
1985
6) Person-years at risk
F12.2
19-30
7) Number entering study
F6.0
37-42
8) Number of deaths
F6.0
31-36
9) Kerma:
F10.2
43-52
mean total gamma component (mGy)
(shielding of surrounding structures or terrain taken into account)
10) Kerma:
F10.2
mean total neutron component (mGy)
53-62
(shielding of surrounding structures or terrain taken into account)
I3
Name
Description
11) Kerma:
F10.2
Cols.
mean total kerma (mGy)
Output
Format
63-72
(shielding of surrounding structures or terrain taken into account)
Note: Before mean total gamma and mean total neutron components
were calculated, total kerma estimates above 6 Gy were truncated
to 6 Gy; gamma and neutron components were adjusted so that: a)
their sum was 6 Gy, and b) the ratio of gamma ray to neutron
kerma was equal to the average value of this ratio for survivors
in the same city whose total kerma estimate was between 4 and 6
Gy.
12) Mean years since exposure
F10.2
73-82
13) Mean age-at-exposure (in years)
F10.2
83-92
Note: Means in 9) to 13) above are person-year weighted,
cell-specific averages over the people at risk in the cell.
Number of cancer deaths for:
14) Leukemia
F5.0
15) All cancers except leukemia
F5.0
93-97
98-102
16) Lip, oral cavity, and pharynx
F5.0
103-107
17) Digestive organs and peritoneum
F5.0
(includes esophagus, stomach, small intestine, colon,
rectum, liver, gallbladder, and pancreas)
108-112
18) Esophagus
F5.0
113-117
19) Stomach
F5.0
118-122
20) Large intestine, except rectum
F5.0
123-127
21) Rectum
F5.0
128-132
22) Liver and intrahepatic bile ducts
F5.0
133-137
23) Gall bladder and extrahepatic bile ducts
F5.0
138-142
24) Pancreas
F5.0
143-147
25) Respiratory system and intrathoracic organs
148-152
F5.0
(includes nasal cavities, middle ear, accessory sinuses,
larynx, trachea, bronchus, lung, pleura, thymus, heart,
and mediastinum)
26) Trachea, bronchus, and lung
F5.0
153-157
27) Female breast
F5.0
158-162
28) Cervix uteri and uterus
F5.0
163-167
29) Cervix uteri
F5.0
168-172
30) Ovary and other uterine adnexa
F5.0
173-177
31) Prostate
F5.0
178-182
32) Bladder, kidney, and other or unspecified
F5.0
urinary
183-187
33) Kidney and ureter
F5.0
188-192
34) Skin (including melanomas)
F5.0
193-197
35) Skeleton
F5.0
198-202
36) Malignant lymphoma
F5.0
203-207
37) Multiple myeloma
F5.0
208-212
38) Non-cancer disease total
213-217
F5.0
(except diseases of the blood and blood-forming organs)
39) Infectious diseases
F5.0
218-222
40) Diseases of the circulatory system
F5.0
223-227
41) Cerebrovascular diseases (Stroke)
F5.0
228-232
42) Heart disease
F5.0
233-237
43) Diseases of the respiratory system
F5.0
238-242
44) Diseases of the digestive system
F5.0
243-247
45) Other diseases
F5.0
248-252
Format for Body Transmission Factor File
DS86TF.DAT
File Name
#Records
DS86TF.DAT
Record Length
90
File Format:
#Variables/Record
30
6
File Size
(Bytes)
2977
IBM PC-DOS 3.1
3.5-inch 1.44 MB, or 5.25-inch 1.2 MB
Study Population: Members of the DS86 subcohort as defined in RERF Life
Span Study Report 11 and RERF Technical Report 9-87 for whom direct DS86
estimates could be computed and who were between 1000-1600 meters from
the
hypocenter in Hiroshima or 1000-2000 meters from the hypocenter in
Nagasaki.
Creation Date:
2 December 1987
Cross-classification variables are items 1-3.
Summary variables are items 4-6.
For each cell in the table, mean gamma ray and mean neutron body
transmission factors are computed for each of the fifteen organs
incorporated into the DS86 system. The table is cross-classified by city
and age as well. The age groups chosen reflect the use of three
different
phantoms in the DS86 system; choice of the appropriate phantom was based
upon age of the individual at the time of exposure.
Output
Name
1) Organ
01
02
03
04
05
06
07
08
09
10
11
12
13
14
15
Description
=
=
=
=
=
=
=
=
=
=
=
=
=
=
=
Skeleton
Marrow
Urinary bladder
Brain
Breast
Eye lens
Large intestine
Liver
Lung
Ovary
Pancreas
Stomach
Testes
Thyroid
Uterus
Cols.
Format
1-2
I2
Cols.
4
Output
Format
I1
3) Age at Exposure
1 = Infant (0-2 years)
2 = Child (3-11 years)
3 = Adult (12+ years)
6
I1
4) Number of Cases
9-12
I4
Name
2) City
Description
1 = Hiroshima
2 = Nagasaki
5) Mean neutron body transmission factor
F5.3
14-18
6) Mean gamma body transmission factor
F5.3
22-26
Disease Groupings and Corresponding ICD Codes:
LSS Mortality File CMDDS86.R11
7th
8th
9th
Cause(s) of Death
Rev.
Rev.
Rev.
-------------------------------------------------------------------------Leukemia
204
204-207
204-208
-------------------------------------------------------------------------ll cancers
140-203
140-203
140-203
except leukemia
205
208-209
-------------------------------------------------------------------------Lip, oral cavity,
140-148
140-149
140-149
and pharynx
-------------------------------------------------------------------------Digestive Organs
150-155
150-159
150.0-155.1
and peritoneum
157-159
156.0-159.9
(includes esophagus,
stomach, small
intestine, colon,
rectum, liver,
gallbladder, and
pancreas)
-------------------------------------------------------------------------Esophagus
150
150
150
-------------------------------------------------------------------------Stomach
151
151
151
-------------------------------------------------------------------------Large intestine,
153
153
153
except rectum
-------------------------------------------------------------------------Rectum
154
154
154
-------------------------------------------------------------------------Liver and Intrahepatic 155.0,155.8
155
155.0,155.1
Bile Ducts
-------------------------------------------------------------------------Gall bladder and
155.1
156
156
extrahepatic bile duct
-------------------------------------------------------------------------Pancreas
157
157
157
-------------------------------------------------------------------------Respiratory system
160-164
160-163
160-165
and Intrathoracic
Organs
------------------------------------------------------------------------Trachea, bronchus,
162,163
162
162
and lung
------------------------------------------------------------------------Female breast
170 (a)
174 (a)
174
------------------------------------------------------------------------Cervix uteri and uterus 171-174
180-182
179-182
------------------------------------------------------------------------Cervix uteri
171
180
180
------------------------------------------------------------------------Ovary and other
175
183
183
uterine adnexa
------------------------------------------------------------------------Prostate
177
185
185
------------------------------------------------------------------------Bladder, kidney, and
180,181
188,189
188,189
other or unspecified
urinary organs
------------------------------------------------------------------------Kidney and Ureter
180
189.0,189.1
189.0-189.2
189.2
189.4,189.8
189.9
------------------------------------------------------------------------------------------------------------------------------------------------Skin (including
190-191
172-173
172-173
melanomas)
------------------------------------------------------------------------Skeleton
196
170
170
------------------------------------------------------------------------Malignant lymphoma
200-202
200-202
200-202
------------------------------------------------------------------------Multiple myeloma
203
203
203
------------------------------------------------------------------------Noncancer except
001-799 except
000-799 except
001-799 except
diseases of the blood
140-239
140-239
140-239
and blood-forming
290-299
280-289
280-289
organs
------------------------------------------------------------------------Infectious diseases
001-138
000-136
001-139
511.9
------------------------------------------------------------------------Diseases of the
330-334
430-438
430-438
circulatory system
400-468
390-429
390-429
440-458
440-459
------------------------------------------------------------------------Cerebrovascular
330-334
430-438
430-438
diseases (Stroke)
------------------------------------------------------------------------Heart disease
400-468
390-429
390-429
440-458
440-459
------------------------------------------------------------------------Diseases of the
470-529
460-519
460-510
respiratory system
511.0,511.1,511.8
512-519
------------------------------------------------------------------------Diseases of the
530-587
520-577
520-579
digestive system
------------------------------------------------------------------------Other diseases
(Noncancer diseases codes except for diseases of
the blood and blood-forming organs, and excluding
those
above categories)
------------------------------------------------------------------------(a) Females only