CURRICULUM VITAE Holly Howard Hobart, Ph. D. January 2006 Address: University of Nevada School of Medicine Molecular Cytogenetics Laboratory 1707 W. Charleston, Suite 110 B Las Vegas, NV 89102 Phone: FAX: Email: (702) 671-5055 (702) 671-0193 [email protected] EDUCATION 1991 – 1993 Indiana University Medical School, Indianapolis, Indiana Department of Medical and Molecular Genetics Postdoctoral Fellowship in Human Cytogenetics Concentration: Molecular Cytogenetics August 1991 University of Arizona, Ph.D., Tucson, Arizona Concentration: Cytogenetics, Genetics, Ornithology and Evolutionary Biology 1984 University of Arizona, M.S., Tucson, Arizona, Program: Ecology and Evolutionary Biology 1971 – 1981 Texas A&M University, College Station, Texas Department of Wildlife and Fisheries Science Master’s Program Project: Feeding Ecology of Roseate Spoonbills 1970 Rice University, B.A., Houston, Texas Major: Economics BOARD CERTIFICATION 2003, 2005 1993 8 March 2016 Renewal of American Board of Medical Genetics Certification Diplomate, American Board of Medical Genetics Curriculum Vitae Holly H Hobart, Ph.D. Page 2 of 5 PROFESSIONAL EXPERIENCE 1 April 2001 - Present Research Associate Professor Laboratory Director, Molecular Cytogenetics Laboratory Department of Pediatrics University of Nevada School of Medicine November 2000 – 31 March 2001 Laboratory Director, Locum Tenens Cytogenetics Laboratory Children’s Hospital of Eastern Ontario Ottawa, Ontario, Canada November 1993 – November 1999 Laboratory Director, Palo Verde Laboratory Tempe, Arizona 1988 – 1990 Bench Technician Molecular Biology Laboratory of Jerry Johnson Department of Molecular Biology University of Wyoming, Laramie, Wyoming 1989-1990 Lecturer- Introductory Biology Department of Zoology University of Wyoming, Laramie, Wyoming AFFILIATIONS 1993 – 1999 Fellow, American College of Medical Genetics American Society of Human Genetics Association of Genetics Technologists American Association for the Advancement of Science American Ornithologists’ Union Cooper Ornithological Society AWARDS AND GRANTS 1991-1993 NIH Postdoctoral Training Fellowship Department of Medical and Molecular Genetics Indiana University Medical School, Indianapolis, Indiana 1986-1988 Doctoral Dissertation Improvement Grant National Science Foundation 1987 James Silliman Memorial Fund University of Arizona Curriculum Vitae Holly H Hobart, Ph.D. Page 3 of 5 AWARDS AND GRANTS - continued 1984 The Chapman Fund American Museum of Natural History 1984 Research Award, American Ornithologists’ Union 1984 Summer Support Award Graduate College, University of Arizona 1984-1985 James Silliman Memorial Fund University of Arizona 1982 Graduate Student Program Development Fund Grant Graduate College, University of Arizona PUBLICATIONS Bilateral Semilunar Valve Disease In A Child With Partial Deletion Of The Williams-Beuren Syndrome Region Is Associated With Elastin Haploinsufficiency. Robert B. Hinton, Jr. M.D., Gail H. Deutsch M.D., Jeffrey M. Pearl M.D., Holly H. Hobart Ph.D., Colleen A. Morris M.D., D. Woodrow Benson M.D., Ph.D., in Press. The Journal of Heart Valve Disease. Chloride channel genes and long QT syndrome. Kendra W Kimberley, Fiona Britton, Colleen A Morris, Holly H Hobart. in prep. BAC-FISH refutes evidence of an 8p22-8p23.1 inversion or duplication in 7 patients with Kabuki syndrome. Kendra W Kimberley, Colleen A Morris and Holly H Hobart. BMC Med Genet. 2006 May 18;7(1):46 [Epub ahead of print] Armstrong L, Allanson JE, Weaver DD, Bevan CJ, Hobart HH. Unrelated patients with a rearrangement of chromosome 2 causing duplication of 2p23 and deletion of 2q37. Am J Med Genet A. Apr 30;134(3):299-304, 2005. Morris CA, Mervis CB, Hobart HH, Gregg RG, Bertrand J, Ensing GJ, Sommer A, Moore CA, Hopkin RJ, Spallone PA, Keating MT, Osborne L, Kimberley KW, Stock AD: GTF2I hemizygosity implicated in mental retardation in Williams syndrome: genotype-phenotype analysis of five families with deletions in the Williams syndrome region. Am J Med Genet. 123A:45-59, 2003. Stock AD, Spallone PA, Dennis TR, Netski D, Morris CA, Mervis CB, Hobart HH: Heat shock protein 27 gene: chromosomal and molecular location and relationship to Williams syndrome. Am J Med Genet. 120A:320-5, 2003. Priest JH, Brothman AR, Christine B, Flejter WL, Haag MM, Henry GP, Hobart HH, Lowery MC, McConnell TS, McGavran L, Peakman DC, Richkind KE, Spector EB: Assessment of clinical cytogenetic laboratories: A five-year experience in the Mountain States Regional Genetic Services Network (MRGSN). Applied Cytogenetics, 23:7, 1997. Curriculum Vitae Holly H Hobart, Ph.D. Page 4 of 5 PUBLICATIONS, continued Meyne J, Baker RJ, Hobart HH, Hsu TC, Ryder OA, Ward OG, Wiley JE, Wurster-Hill DH, Yates TL, Moyzis RK: Distribution of non-telomeric sites of the telomere repeat sequence (TTAGGG)n in vertebrate chromosomes. Chromosoma, 99:3-10, 1990. Yu Q-X, Hobart HH: Chromosome banding pattern homologies of the Common Moorhen (Gallinula chloropus) and the domestic Chicken (Gallus domesticus). Acta Zoologica Sinica, 36:194-200, 1990. Hobart HH, Gunn SJ, Bickham JW: Karyotypes of six species of North American blackbirds (Icteridae: Passeriformes). Auk, 99:514-518, 1982. Hobart HH, DeKeyzer D: A nesting record for Mississippi Kites in Ft. Bend County, Texas. Bull Tex Ornith Soc, 12:50-52, 1979. PRESENTATIONS Hobart HH, Gregg RG, Mervis CB, Robinson BF, Kimberley KW, Rios CM, Morris CA. Heterozygotes for the microinversion of the Williams-Beuren syndrome region have an increased risk for affected offspring. Presented at the Annual Meeting of the American Society of Human Genetics, Toronto, Canada, October 2004. Kimberley KW, Britton FC, Hume JR, Hobart HH, Morris CA. A new polymorphism in chloride channel gene 2. Presented at the Annual Meeting of the American Society of Human Genetics, Toronto, Canada, October 2004. Rios CM, Morris CA, Gregg RG, Cambron K, Kimberley KW, Mervis CB, Robinson BF, Signorelli D, Hobart HH. Research Studies in Williams-Beuren syndrome. Presented at the annual meeting of the Association of Genetics Technologists, Anaheim, CA, June 2004. Hobart HH, Gregg RG, Mervis CB, Robinson BF, Kimberley KW, Rios CM, Morris CA. Frequency of the inversion encompassing the Williams-Beuren syndorme region in parents and in the general population. Presented at the Annual Meeting of the American College of Medical Genetics, Orlando, FL March 2004. Claydon MA, Ross K, Hart G, Hobart HH: Bloody amnios: A solution? Poster presentation at Association of Genetics Technologists Annual Meeting, June, 1999. Orlando, Florida. Priest JH, Adams WR, Sanford-Hanna J, Hobart HH, Saxe DF, Sanders T, McGavran L, Perszyk AA, Spector EB, Stone JF: The nature of recurrent triploidy in humans. Poster presentation at the annual meeting of the American Society of Human Genetics, October, 1995. Minneapolis, Minnesota. Babini S, Sheppard LC, Hobart HH: A tale of two chromosomes: Przewalski’s horse and karyotypic evolution in Equidae. Paper presented at the 33rd annual American Cytogenetics Conference, April, 1995. San Diego, California. Curriculum Vitae Holly H Hobart, Ph.D. Page 5 of 5 Hobart HH: Rates of karyotypic evolution in some groups of birds. Paper presented at the 33rd annual American Cytogenetics Conference, April, 1995. San Diego, California. PRESENTATIONS – Continued Hobart HH, Zhang A, Weaver DD, Vance GH, Palmer CG: Frequent occurrence of duplications among de novo chromosome rearrangements. Poster presented at the annual meeting of the American Society of Human Genetics, October, 1993. Hobart HH, Palmer CG: Evaluation of a strategy for directed in situ hybridization for identification of de novo rearrangements. Paper presented at 31st Annual American Cytogenetics Conference, March 28-31, 1993. Port Ludlow, Washington. Hobart HH, Yu Q-X: A comparative karyology of some chickadees (Paridae), Verdin (Auriparus flaviceps), and Bushtit (Psaltriparus minimus). Paper presented at 31st Annual American Cytogenetics Conference, March 28-31, 1993. Port Ludlow, Washington. Hobart HH: A case of congenital leukemia. Paper presented at the annual Ohio Valley Regional Cytogenetics Meeting, May, 1992. Lexington, Kentucky. Hobart HH: Comparative karyology of five genera of Parulinae. Poster presented at the meeting of the American Ornithologists’ Union, August, 1987. San Francisco, California. Hobart HH: Chromosomal variation in passerine birds. Paper presented at the 24th Annual Somatic Cell Genetics Conference, January 12-15, 1986. Key West, Florida. Hobart HH, Stock AD: Chromosomal banding homologies of North American doves and pigeons. Paper presented at the meeting of the American Ornithologists’ Union, Mississippi State University, Mississippi, 1986. Stock AD, Hobart HH: Chromosomal banding pattern homologies in North American doves and pigeons (Columbiformes). Paper presented at the 23rd Annual Somatic Cell Genetics Conference, January 20-23, 1985. San Diego, California. Hobart HH, Groschupf K: Chromosomal variation in Aimophila and relatives. Poster presented at the meeting of the American Ornithologists’ Union, October, 1985. Tempe, Arizona. Hobart HH: Karyotypes of some Arizona birds. Paper presented at the Spring 1984 meeting of the Arizona-Nevada Academy of Sciences meeting. Tucson, Arizona.