2008-02-08 BEL – ME2306 Atlas Antibodies Question formulation, purpose and method Alexander Grankvist Kasper Karlsson Martin Lagerblad Pontus Sundqvist BACKGROUND A great quantity of information has emerged from the Human Proteome Resource project (HPR). This information contains great value both for medical studies, as well as a contribution to the market supplying biomedical technology. Atlas Antibodies AB today holds the intellectual property rights to biomarkers discovered within the HPR. In addition, Atlas Antibodies holds the right to commersialize the monospecific antibodies developed by HPR. Atlas Antibodies started their sales of antibodies the fall of 2006. Today they are at the breaking point of starting to outlicense potential cancer biomarkers and intend to analyze this market. PROBLEM Our ambition, while conducting this research, is to analyze and investigate the future market for the biomarkers that Atlas Antibodies will be providing. This problem is said to be an open question alignment (Eriksson, Widersheim-Paul, 2006). This implies that we want to propose a first view of the market, our first analyze might lead to a more profound investigations following up. The main problem is constructed of a series of sub problems, for which we intend to seek answers: What does the future cancer diagnostic market look like? What is the market size for cancer diagnostic products focusing on Antibody based products? What type of deals has been made in the out licensing of biomarkers, how can we value these deals and what kind of deal structure is most common? Who are the market leaders in cancer diagnostics? PURPOSE Our purpose with this study is to give a broad investigation and quantification of the market of cancer diagnostics based on biomarkers. The focus of this market analysis will be based on the market for the products that may be developed against the pipeline of potential cancer biomarkes identified and validated by Atlas Antibodies. The study will be based on the information retrieved while interviewing and conducting research in the field of cancer diagnostic product in general, and specifically cancer biomarkers. A secondary purpose of this study is to educate our self in the field of analyzing pharmaceutical markets METHODS The bulk of the report will be based on information retrieved with the help of qualitative methods. This qualitatively obtained information will consist of interviews with leading academic researches and industry experts as well with members of the medical profession. In addition, information about the cancer diagnostic market will be obtained from industry reports and from annual reports from large companies in the field. The information about different types of licensing deals and payment structures will be mainly obtained from public information (newspaper articles and annual reports). The interviews will be (if possible) conducted in personal if the person to be interviewed is in the Stockholm area, in other cases by telephone. Questions will be prepared beforehand but the aim of the interviews is not that the interviewee is to answer all of 2008-02-08 Alexander Grankvist BEL – ME2306 Kasper Karlsson Atlas Antibodies Martin Lagerblad Question formulation, purpose and method Pontus Sundqvist them. They are just to serve as guidance for the interview. The interviews will (when allowed) be taped. This description of methods used will be expanded and clarifyed as the project goes on. THEORETICAL FRAMEWORK The theoretical framework will be applyed on the information retrieved and will be used to make conlusions and serve as guidance for answering the questions stipulated in the report. We have decided to use SWOT ananlysis, PEST analysis and Porters Five Forces analysis, which we cosider to be good tools. By combining these we believe that we will be able to deliver a rich market analysis. SWOT analysis One of the most used strategic analysis models is called the SWOT analysis. SWOT stands for: Strengths, Weaknesses, Opportunities and Threats. The analysis can be divided into two parts, one internal and one external. The internal part consists of analysing the companies own Strengths and Weaknesses. The external part is an evaluation of the Opportunities and threats present in the external environment that the company is, or considers being, active in. Altogether these perspectives give a good picture of the company’s current situation and the possibility of reaching its strategic goals. PEST analysis The environment of a company can be divided in internal and external environment. The external environment can be divided in a micro, e.g. external customers, agents and distributors, suppliers, competitors, etc, and a macro-level. PEST analysis is a tool to analyse the macro-environment. It includes the poltical, economical, sociocultural and technological factors. It gives a broad overview of which factors. PEST factor are usually out of the grasp for companies, and can be translated to Threats and Opportunities in a SWOT analysis. Porters Five Forces Porters Five Forces model is a useful tool to understand how attractive a market is to be in. The Five Forces are: Threat of new entry Buyer Power Supplier Power Threat of Substitution Competitive Rivalry The model describes under what conditions the different forces are likely to be high and what the implications usually are. An overall high pressure from these five areas will give lower profitability. Eriksson, L & Widersheim-Paul, F, 2006, Att utreda och forska, Liber, Malmö