Name: __________________________________
Apple Genomics Crossword
DIRECTIONS:
Using the clues on the other side of this worksheet and the list of vocabulary
words from the Apple Genomics website, fill in the crossword below. As an
added challenge, you may try identifying the vocabulary word that goes with
each clue before looking at the crossword puzzle.
Across
2. The portion of a plant that contains seeds.
4. One of four nucleic acids; complements guanine.
5. A discrete unit of hereditary information consisting of a specific nucleotide sequence in DNA.
9. A small ring of DNA separate from the chromosome(s), found in prokaryotes and yeast.
10. An organic acid containing a carboxyl (-COOH) group and an amino (-NH2) group.
12. A large set of cloned DNA molecules spotted onto a solid matrix (such as a microscope slide) for use in
probing a biological sample to determine gene expression, marker pattern or nucleotide sequence of DNA or
RNA.
13. A structure within the nucleus of a eukaryotic cell where ribosomal RNA is made and assembled with
proteins to make ribosomal subunits.
17. An enzyme that is essential for DNA replication and that catalyzes the covalent bonding of adjacent DNA
nucleotides; used in genetic engineering to paste a specific piece of into a vector.
19. A cooperative unit of many similar cells that perform a specific function within a multi-cellular organism.
20. A protein that serves as a biological catalyst, changing the rate of a chemical reaction without itself being
changed into a different molecule in the process.
Down
1. A discipline that uses knowledge of hereditary biochemistry to alter the genetic makeup of living things.
3. To form base pairs between complementary regions of two strands of DNA that were not originally paired.
6. In eukaryotes, a non-expressed (non-coding) portion of a gene that is excised from RNA.
7. The synthesis of a polypeptide using the genetic information encoded in an mRNA molecule.
8. Enzyme that catalyzes the synthesis of nucleic acids on preexisting nucleic acid templates, assembling RNA
from ribonucleotides or DNA from deoxyribonucleotides.
11. An apparatus consisting essentially of a compartment spun about a central axis to separate colloidal particles
suspended in a liquid.
14. A cell organelle consisting of RNA and protein organized into two subunits and functioning as the site of
protein synthesis in the cytoplasm.
15. A disease-causing organism.
16. A piece of DNA, usually a bacterial plasmid or a viral genome, that is used to move genes from one cell to
another.
18. Single-celled prokaryotes with a single chromosome, multiple plasmids, and no cellular organelles.
Apple Genomics Crossword KEY
Across
2. Fruit
4. Cytosine
5. Gene
9. Plasmid
10. Amino
12. Microarray
13. Nucleolus
17. Ligase
19. Tissue
20. Enzyme
Down
1. Biotechnology
3. Hybridize
6. Intron
7. Translation
8. Polymerase
11. Centrifuge
14. Ribosome
15. Pathogen
16. Vector
18. Bacteria