Fall 2004 - Penn Medicine - University of Pennsylvania

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University of Pennsylvania Health System

Department of Ophthalmology Scheie Eye Institute

T

HE

S

CHEIE

L

OOKING

G

LASS

Fall, 2004 Volume 5, Number 2

EYE

ON

EDUCATION

A M

ESSAGE

FROM THE

C

HAIR

INSIDE

THIS ISSUE:

Medical Student

Education

Resident Education

2-3

4-9

Fellowships 10-12

Post Doc &

Graduate Students 13-15

16-17 K12 Award

The 130th

Anniversary 18-19

Classes &

Visiting Professors 20-21

Ophthalmology

Review Course 22

Faculty

Lectures & Seminars

23

24 www.penneye.com

In previous issues of the Scheie Looking Glass, we have described the breadth and depth of our department’s clinical and research programs to highlight how we treat patients today and how our research may lead to better treatments tomorrow.

In this issue we portray our commitment to passing knowledge to the next generation of ophthalmologists and vision scientists.

Undergraduates and medical students, residents and fellows, graduate and postdoctoral students, research assistants and faculty – all teach and learn from one another.

A secret to our success in education is our enthusiasm for solving problems in ophthalmology and vision science and the thrill of giving our patients the benefit of discovery.

The opportunities to learn and make new discoveries about the gift of sight are limited only by our motivation and imagination. Penn Ophthalmology provides the rest.

2 • VOLUME 5, NUMBER 2

M

EDICAL

S

TUDENT

E

DUCATION

MEDICAL STUDENTS GET

A FIRST GLIMPSE OF THE EYE

The eye is one of the most accessible organs of the body and can reveal early signs of systemic disease long before a patient experiences symptoms. It is surprising to discover that Penn is one of the few medical schools that requires a course in clinical ophthalmology. Several

Scheie faculty, in collaboration with ophthalmology faculty at other medical schools, are trying to remedy that situation. Prithvi Sankar, M.D.

, a member of the Glaucoma Service, serves as Director of Medical Student Education for Penn Ophthalmology.

Penn is one of the few medical schools that requires a course in clinical ophthalmology.

At Penn, ophthalmology is introduced in the first year of medical school during the course on brain and behavior. After attending a lecture on the anatomy and function of the visual system, students proceed to the laboratory to dissect a cow eye. Faculty mentors supervise this activity.

During the second year, students in groups of ten are scheduled for a oneweek clinical clerkship. This clerkship introduces students to common eye problems, major causes of vision loss in the U.S. and in the world, and major unsolved problems in ophthalmology and vision science. A bonus is that students are exposed to our faculty, providing an interaction that often stimulates an interest in ophthalmology and eye research. The clerkship includes lectures, reading assignments, discussion of interesting cases, and participation in clinics and surgery with both faculty and residents.

In the third year, the department offers a one-month clinical elective during which students attend conferences, participate in clinics, observe in the operating room and meet with faculty several times a week to discuss special topics such as glaucoma, macular degeneration, cataracts, and diabetic retinopathy. This rotation allows for the acquisition of clinical skills such as measuring visual function, using special equipment, and examining the retina with an ophthalmoscope. In addition, students may work on short projects.

In the fourth year, a student can choose to spend from three months to a full year to pursue a research project that is often continued after completion of medical school if the student selects ophthalmology as a career. Three Penn

Medicine graduates from the Class of

2004 - Gena Heidary, Naureen

Mirza and Stacy Pineles , chose to follow this career path and describe their experiences at Scheie.

Prithvi Sankar, M.D., lectures to first-year Penn Medical

Students (first row, left to right) Danielle Darrah, James

Feinstein, Leisha Nolen, Laura Sheiman, Taral Patel,

(second row left to right) Jeremy Brauer

and Rebecca Nerenberg.

STACY PINELES

My ophthalmology experience at

Scheie consisted of a one-week introductory clerkship, a one-month elective which included rotations with many faculty and one-month of neuro-ophthalmology. The neuroophthalmology experience led to a four-month research project with

Nicholas J. Volpe, M.D.

Dr. Volpe and I created a fully automated, combined static and kinetic perimeter test to examine neuro-ophthalmic and glaucoma patients who had visual field defects. We also studied patients with functional visual loss. Our results were reported at the North

American Neuro-Ophthalmology

Society (NANOS) and Association for

Research in Vision and Ophthalmology (ARVO) meetings, and will appear as a brief report in the American Journal of Ophthalmology. We also are preparing a full-length manuscript that will provide more details about our results.

Besides helping me to complete this research project, Dr. Volpe was a generous advisor during my residency application process and helped me to choose programs that best met my needs and career plans. Drs. Fine and

Volpe, and all of the faculty and residents at Scheie, have created a truly nurturing environment for students interested in ophthalmology. After a one-year internship at Harbor-UCLA

Hospital, I will begin residency at the

Jules Stein Eye Institute at UCLA in July

2005.

GENA HEIDARY

Ophthalmology offered me an ideal mix of surgery and clinically driven research. Armed with a Ph.D. in Neuroscience and some expertise in both fly and human genetics, I anticipate focusing my career in ophthalmic genetics. My interests led me to the laboratory of Terri L. Young, M.D.

, a pediatric ophthalmologist and ophthalmic geneticist. Dr. Young’s lab identifies genes that may contribute to hereditary forms of severe nearsightedness or high myopia.

My project, performed in collaboration with Gui-shuang Ying, Ph.D.

, and Maureen G. Maguire, Ph.D.

, both at Scheie’s Center for Preventive Ophthalmology and Biostatistics, investigated the relationship between high myopia and astigmatism.

In severely myopic patients, we found a high prevalence of astigmatism, a relationship that had not been described previously. I presented the results at this year’s annual meeting of the Association for Research in Vision and Ophthalmology.

After completing a transitional internship at UPHS Presbyterian Medical Center, I will begin my residency in ophthalmology at the Massachusetts Eye and Ear Infirmary in July

2005.

THE SCHEIE LOOKING GLASS • 3

NAUREEN MIRZA

During my fourth year of medical school, I worked in the laboratory of

Michael J. Tolentino, M.D.

, whose research focuses on developing novel treatments for age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity. My project was to engineer ocular cells to produce a therapeutic protein and to control where and when the protein is produced. We constructed a virus that could commandeer ocular cells to produce a measurable gene product.

When fully developed, this system could be used to control delivery and to dose therapeutic molecules with a laser. While the majority of my work involved cell culture, a future direction will be to test the system in animals.

My laboratory experience convinced me that new therapies for devastating ocular diseases will be possible only through continued scientific research. I hope to be a part of such innovative medicine.

I will be a transitional intern for one year at Albert Einstein Medical Center in Philadelphia and will begin my residency at Scheie in July

2005.

4 • VOLUME 5, NUMBER 2

R

ESIDENT

E

DUCATION

SCHEIE’S OPHTHALMOLOGY RESIDENCY

Why do more than 400 senior medical students apply for Scheie’s five residency slots each year, making Scheie one of the most sought-after residencies in the country? Since the structure and curriculum of residency programs in the

U.S. are fairly standard, the people in the program make the difference. Students apply to Scheie because our faculty approach teaching with gusto.

Scheie’s program provides breadth and depth in comprehensive ophthalmology, retina and vitreous, glaucoma, neuro-ophthalmology, cornea and external diseases, oculoplastic, orbital and cosmetic eye surgery, pediatric ophthalmology and low vision services.

Our four main clinical facilities (Scheie Eye

Institute, Hospital of the University of

Pennsylvania (HUP), Children’s Hospital of

Philadelphia (CHOP) and the Philadelphia

Veterans’ Administration Medical Center

(VAMC)) offer a diversity of practice environments. Classroom instruction and practice surgery on animal eyes help residents develop confidence in their

Third year resident Linda Rose, M.D., Ph.D., shown performing surgery with

Stephen Orlin, M.D., says, “I value the quality of human contact which is a great backup to learning. There is such great diversity and contrast in faculty styles, yet everyone puts themselves out to help me learn.”

Second year resident B. Michael Walker, M.D., performs an eye exam with visiting medical student Allen Chiang from NYU.

THE SCHEIE LOOKING GLASS • 5

PROGRAM KEEPS THE FUTURE IN SIGHT

newly acquired skills. When a resident is inspired to focus on one particular aspect of ophthalmology, the opportunities for pursuing an exciting research project are numerous. In 2003, the Scheie residency received a full five-year accreditation, the best possible designation, by the

Accreditation Council of Graduate Medical

Education’s Residency Review Committee for Ophthalmology.

First year residents at Scheie learn to perform eye examinations, use ocular instruments and lenses, manage emergencies and perform microsurgery.

They rotate for ten weeks each on the cornea/glaucoma, retina, VAMC, HUP and pathology/oculoplastics services and share call duty with a senior resident and an attending physician for off-hour emergencies. Residents also may begin their first four-week elective to work on clinical or laboratory research projects.

Second year residents spend ten weeks each in pediatric ophthalmology at

CHOP, neuro-ophthalmology, retina/ vitreous, cornea/glaucoma and the VAMC.

Charles Nichols, M.D., Deputy Chief of Ophthalmology at HUP and third year resident

Jason Hsu, M.D., examine patients at HUP.

By the end of the second year, residents have been exposed to the full spectrum of comprehensive ophthalmology and its

David Kozart, M.D., Chief of the Comprehensive Ophthalmology Service and second year resident Newman Sund, M.D., Ph.D.

subspecialties and have performed both intra- and extra-ocular surgery with supervision. Most residents present

Continued on page 6

6 • VOLUME 5, NUMBER 2

Scheie’s Ophthalmology Residency Program Keeps The Future In Sight (Continued)

Students apply to

Scheie because our

results from first year research projects at scientific and professional meetings.

faculty approach

Third year residents focus on honing their surgical skills and

teaching with gusto.

managing post-operative patients.

They also have the unique opportunity to design a ten-week elective to satisfy their interest in a subspecialty, laboratory or international experience. Third year resident Wai Wong,

M.D., Ph.D.

, chose Scheie because “I enjoy basic science and

Scheie has a great research reputation and is strong in my areas of interest - retina and neuro-ophthalmology. The attending physicians treat us like colleagues and give us a nice balance of advice and the benefit of their experience.”

After three years, Scheie graduates are fully trained and ready to practice general ophthalmology or begin subspecialty fellowship training. In recent years most residents have chosen fellowships to prepare either for careers in academic ophthalmology or for private practice in a subspecialty.

Ophthalmologists in training may apply for support from the

Jenny Hall, M.D., second year resident, practices cutting and suturing cow eyes in the wet lab, which she says, “is a great way to get used to working with my hands and the tiny tools under the microscope.”

Thomas Heed

Ophthalmic Foundation which provides modest stipends on a

When a resident is inspired to focus on one particular aspect of

competitive basis. The

Heed Ophthalmic

Foundation awards are among the most

ophthalmology, the opportunities for pursuing

prestigious awarded to young

an exciting research project are numerous.

ophthalmologists who are planning a career in academic ophthalmology. Over the past three years, two applicants who have completed residencies at the Scheie Eye Institute finished first in the competition, thereby garnering the Society of Heed

Ophthalmic Fellows distinction. A third applicant received the only two year fellowship awarded by the Heed Foundation.

Our faculty and staff are proud of their accomplishments.

Third year resident Shane Kim, M.D., and

Michael Sulewski, M.D., at the Veterans Administration

Medical Center in front of the Korean War Memorial.

SCHEIE

Welcomes

New

Residents

THE SCHEIE LOOKING GLASS • 7

CATHERINE CUKRAS, M.D., PH.D.

A graduate of Princeton University, Cathy attended Washington

University School of Medicine in St. Louis, where she also earned a

Ph.D. in Molecular and Cellular Biology, studying phospholipid regulation of potassium channels. Cathy spent last year as an intern in the Presbyterian Transitional Program. She is an accomplished triathlete and flutist.

Stuart Fine, M.D. and

Catherine Cukras, M.D., Ph.D.

review retina photographs prior to examining a patient.

CATHERINE HWANG, M.D.

Cathy hails from Atlanta, GA and was graduated from Emory

University. She completed the Transitional Program at UPMC-

Presbyterian upon graduating from Penn Medical School. Cathy is an expert clarinetist, having performed with the Emory Wind Ensemble, the Atlanta-Emory Orchestra and the Atlanta Olympic Band.

JASON SKALET, M.D.

Jason, a graduate of Amherst College, attended Penn Medical School and worked in the lab of Eric Pierce, M.D., Ph.D. studying mutations in the RP1 gene and their association with retinitis pigmentosa. Prior to completing the Presbyterian Transitional Program, Jason traveled to

Japan to study ophthalmology and Japanese language and culture as part of the Nagoya University

Program for Academic

Exchange.

MADHURA TAMHANKAR, M.D.

Third year resident William

Katowitz, M.D., demonstrates how to use a gonioscope to

Catherine

Hwang, M.D.

Madhura was graduated from the University of Bombay, India where she also completed a residency in ophthalmology. She did research at

Wills Eye Hospital for two years before completing an internship in surgery at Yale University and a fellowship in Neuro-ophthalmology at

Penn/Scheie. Madhura enjoys river rafting with her husband and two children. Rumor has it that her culinary skills are superb.

Second year resident Wayne

Wu, M.D., Ph.D., and Jason Skalet,

M.D. review a patient’s chart.

ROBERT WONG, M.D.

A graduate of Duke University, Bob attended Penn Medical School and completed the transitional year program at Crozer-Chester Medical

Center. During his final year of medical school, Bob worked in the lab of Dr. Joshua Dunaief investigating mechanisms underlying age-related macular degeneration. Bob is an accomplished jazz musician and world traveler, having journeyed to

Hong Kong, Nepal and Peru.

Madhura Tamhankar,

M.D. administers drops to one of her patients.

Robert Wong, M.D.

(right) performs a slit lamp examination supervised by

Paul Tapino, M.D.

8 • VOLUME 5, NUMBER 2

GRADUATING

RESIDENTS

Leonard Feiner, M.D., Ph.D.

, just began a two-year fellowship in vitreoretinal surgery at Barnes

Retina Institute, Washington

University, St. Louis, MO.

Len received a two year fellowship award from the Heed Ophthalmic

Foundation.

Michael Tracy, M.D.

, is performing a cornea fellowship at Bascom Palmer Eye Institute at the University of Miami.

Three residents from the Class of 2004,

Gabrielle Bonhomme, M.D.

,

Damon Chandler, M.D.

, and

Leila Khazaeni, M.D.

, chose to remain at Penn for their fellowships.

Please read about them in the fellowship article on page 10____.

Residency Review

Committee Chooses

Scheie Resident

Scheie’s leaders in education are not limited to its faculty and staff.

Gil Binenbaum, M.D.

, was selected to serve as the sole resident member of the

Residency Review Committee for

Ophthalmology (RRC), the group responsible for residency program accreditation in the United States.

Operating under the auspices of the

Accreditation Council for Graduate

Medical Education, the RRC is composed of ten members, (9 of the 10 are ophthalmologists) three each appointed by the American Academy of

Ophthalmology, the American Board of

Ophthalmology, and the American

Medical Association, and one current resident in ophthalmology. The committee establishes academic standards for all aspects of residency education and reviews each individual residency every two to five years to ensure compliance with those standards.

As resident member of the RRC,

Binenbaum will serve a two-year term and be a full-voting member of the committee. This appointment is a careerdefining opportunity for Binenbaum who is interested in medical education. He received his undergraduate degree from the Wharton School at Penn and had a successful career as a foreign exchange trader before returning to the University of Pennsylvania for medical school. At

Penn Med, he became active in curricular reform and began to set his sights on a career in academic ophthalmology. He plans eventually to become a residency program director, a goal towards which his work on the RRC should provide valuable experience.

Gil appreciates,

“the approachable, family-like tone set by Chair, Stuart

Fine; Residency

Director, Nicholas

Volpe’s design of the rotations; and their response to residents’ concerns.”

THE SCHEIE LOOKING GLASS • 9

LEADERSHIP

Nicholas J. Volpe, M.D.,

Residency Program Director , is largely responsible for the well-rounded format of the residency. Volpe’s interest in ophthalmic education began during his own residency and fellowship years at the Massachusetts Eye and Ear

Infirmary. He realized that he derived enormous satisfaction from interactions with residents in the clinic, operating room and classroom and by collaborating with them on projects. He also was struck by the fact that

“ophthalmic education often was left to chance.” Consequently, he decided early in his career that improving ophthalmic education would be an integral part of his professional future.

Volpe’s commitment to ophthalmic education extends to the national level.

He has led the surgical arm of the

American Board of Ophthalmology’s task force to develop methodologies for teaching and evaluating surgical competency. Along with other program directors, he organized and taught courses and symposia with the goal of improving all aspects of residency education. During the past year, he served as chair of the residency program directors division of the

Association of the University Professors of Ophthalmology (AUPO), and recently was named as the recipient of the prestigious Bradley R. Straatsma Award for Excellence in Resident Education.

Volpe attributes much of his success to the unwavering support he receives from department Chair Stuart Fine,

“who has allowed him to devote the time, effort and resources worthy of this important endeavor.”

Paul J. Tapino, M.D.

, was recently appointed as Deputy Residency

Program Director . In his role as

“COO” of the residency, Tapino is responsible for organizing lectures, clinical rotations, and attending schedules, orienting new residents, and teaching the basics of eye examinations.

Tapino also runs the inpatient consult service with the residents, teaches the residents in the clinic, operating room and classroom, and intervenes whenever problems arise.

Education Coordinator,

Jenny Bartelle orchestrates the dayto-day activities which run the gamut from reviewing residency applications, scheduling interviews, verifying credentials, creating and assembling materials for interviews, helping to organize the curriculum, providing documentation for medical student, residency and continuing medical education courses, and lending the occasional shoulder to cry on.

Institute Director Stuart L.

Fine, M.D.

is committed to providing the support needed for the best possible residency experience. Fine,

Volpe, Tapino and Bartelle meet with the resident group monthly to obtain feedback and to discuss potential improvements.

Scheie Education Leadership from left to right:

Paul Tapino, M.D., Prithvi Sankar, M.D.,

Nicholas Volpe, M.D., Jenny Bartelle and Stuart Fine, M.D.

10 • VOLUME 5, NUMBER 2

F

ELLOWSHIPS

Welcome

to the

New

Fellows

HINA AHMED, M.D., GLAUCOMA FELLOW

Hina was graduated from Dartmouth College. She attended Wright State

University School of Medicine and completed her residency in ophthalmology at

Case Western Reserve University. Hina looks forward to the clinical, surgical and teaching challenges that await her. We welcome her back East!

GABRIELLE BONHOMME, M.D., NEURO-OPHTHALMOLOGY FELLOW

Gabrielle, a Washington, D.C. native, is no stranger to the Penn/Scheie community. She was graduated from Penn Medical School and completed the residency program at Scheie in June 2004. In her free time, Gabrielle enjoys running, playing the piano and spending time with her family.

SUBSPECIALTY

FELLOWSHIPS

Ophthalmologists who want to subspecialize in a particular area must undergo one to two years of additional training. Penn offers fellowships in glaucoma, neuro-ophthalmology, oculo-plastic surgery, pediatric ophthalmology, medical retina, and vitreoretinal diseases and surgery. Each fellowship provides indepth clinical and research experience in the fellow’s chosen area. Fellows interact closely with clinical faculty, vision scientists, residents, and medical students. They attend both general conferences and subspecialty conferences and typically engage in clinical and/or basic research during the course of the fellowship.

DAMON CHANDLER, M.D., OCULOPLASTICS FELLOW

Damon spent 8 years at Duke as an undergraduate and medical student followed by a General Surgery internship at Massachusetts General Hospital.

He too is a recent graduate of the Scheie residency program and will be the first

Oculoplastics fellow working with Dr. Roberta Gausas. Art history, classical music, and racquetball keep Damon busy when not at Scheie.

LEILA KHAZAENI, M.D., PEDIATRIC OPHTHALMOLOGY FELLOW

Leila, another of the 2004 Scheie residency graduates, received her medical degree from University of Michigan where she also completed her internship. She is an avid marathon runner and completed the NY Marathon this year. Keep an eye out for her along the Kelly and West River Drives!

Damon Chandler, M.D.

and Roberta Gausas, M.D.

prepare to do surgery.

Our department’s fellowship programs offer strong clinical, surgical, and research training. The fellows gain exposure from working in several hospitals and are exposed to many clinical and research faculty.

The continuum of education from medical students to residents to fellows is one of the great strengths of the Scheie Eye Institute.

MELANIE MCCARTY, M.D., OCULOPLASTICS FELLOW

Melanie was graduated from University of Alabama School of Medicine. She completed her internship at Baptist Hospital Systems in Birmingham and residency at University of Tennessee Health Science Center. She enjoys running, eating and lots of shopping.

Hina Ahmed, M.D., responds to a message from a patient.

Gabrielle Bonhomme, M.D. and

Nicholas Volpe, M.D. review a CAT scan.

Continuing

Fellows

THE SCHEIE LOOKING GLASS • 11

George Mayo, M.D. and

Alexander Brucker, M.D. review a fluorescein angiogram.

Goodbye

to the Graduating Fellows

STEFANIE DAVIDSON, M.D.

Stefanie completed her training in pediatric ophthalmology and has joined the faculty at CHOP.

Carolyn Glazer-Hockstein, M.D.

with Joshua Dunaief, M.D., Ph.D.

HEATHER (FOGT) DEALY, M.D.

Heather joined the

Brandywine Eye

Center in

Wilmington, DE after completion of a glaucoma fellowship at Scheie.

CAROLYN GLAZER-HOCKSTEIN, M.D., MEDICAL RETINA

Carolyn completed her residency at Scheie. As the current medical retina fellow, she works closely with the retina faculty in the clinic, learning the spectrum of retinal pathology. She also has completed coursework in medical epidemiology.

According to Glazer-Hockstein, “the medical retina fellowship at Scheie is different because the fellow examines patients with all the retina faculty, not just medical retina.”

GEORGE MAYO, M.D.

, VITREORETINAL SURGERY

Geroge, a Penn medical graduate and lieutenant commander in the United States

Naval Reserve, completed a residency in San Antonio, Texas prior to becoming the vitreo-retinal surgical fellow. He participates actively in the busy operating room and the clinics at Scheie. He also helps to run the VA retina clinical and surgical services under the supervision of Robert Stoltz, M.D., Ph.D.

Melanie McCarty, M.D. and

Jim Katowitz, M.D.

FEMIDA KHERANI, M.D.

Femida returned home to her native Canada after completing her training in oculoplastics and is joining a group practice in Calgary,

Alberta.

Leila Khazaeni, M.D. (right) and Monte Mills, M.D.

KENNETH SHINDLER, M.D., PH.D.

Kenneth joined the

Scheie neuroophththalmology faculty as a clinicianscientist following the completion of a oneyear neuroophthalmology fellowship.

12 • VOLUME 5, NUMBER 2

THE SCHEIE EYE INSTITUTE

FELLOWSHIP PROGRAMS

GLAUCOMA OCULOPLASTICS

• 1 year

• Preceptors:

Jody R. Piltz-Seymour, M.D.

Eydie G. Miller-Ellis, M.D.

Prithvi S. Sankar, M.D.

• Clinical Research

Ocular Hypertension

Treatment Study

(OHTS)

NEURO-

OPHTHALMOLOGY

Collaborative Initial

Glaucoma Treatment

Study (CIGTS)

Memantine trial

Corneal thickness in juvenile glaucoma

Long-term visual fields survival in advanced glaucoma

• 2003-2004 Fellow:

Heather Dealy, M.D.

• 2004-2005 Fellow:

Hina Ahmed, M.D.

• 1 year: fellows must have completed residency in either ophthalmology or neurology

• Preceptors:

Nicholas J. Volpe, M.D.

Steven L. Galetta, M.D.

Dina Jacobs, M.D.

Grant T. Liu, M.D.

Laura Balcer, M.D.

Kenneth S. Shindler,

M.D., Ph.D.

• Clinical Research

Optic neuritis

Visual fields

Computerized

Goldmann perimetry

Adult strabismus surgery

Pupillometry

Clinical trials in MS

• 2003-2004 Fellow:

Kenneth S. Shindler,

M.D., Ph.D.

• 2004-2005 Fellow:

Gabriel Bonhomme,

M.D.

• www.upno.org

• 2 year ASOPRS approved fellowship

• Preceptor:

James A. Katowitz, M.D.

• Principal venues CHOP,

HUP, VAMC, outside practices

• Clinical Research

Orbital volumetric studies

Fetal surgery and wound healing

Comparison of various synthetic materials in ptosis repair

Orbital and socket expansion with hydrogel in congenital microphthalmia

Genetic relationships in congental microphthalmia

• 2003-2004 Fellow:

Femida Kherani, M.D.

• 2004-2005 Fellow:

Melanie McCarty, M.D.

• 1 year fellowship

• Preceptor Roberta E.

Gausas, M.D.

• Principal venues SEI,

HUP, VAMC, outside practices

PENN

offers fellowships in glaucoma neuro-ophthalmology oculoplastic surgery pediatric ophthalmology medical retina

• 2004-2005 Fellow:

Damon Chandler, M.D.

• Both fellowships include extensive rotations at

HUP and CHOP in

Plastic Surgery, ENT,

Maxillo-facial Surgery,

Trauma, Dermatology,

Neurosurgery, and

Neuroradiology

vitreoretinal diseases and surgery.

PEDIATRICS

• 1 year

• Intend to offer 2 positions in 2005-2006

• Preceptors:

Monte D. Mills, M.D.

Graham E. Quinn, M.D.

Brian J. Forbes, M.D.

Eric A. Pierce, M.D., Ph.D.

Terri L. Young, M.D.

Stefanie Davidson, M.D.

• Clinical Research

Prevention of progressive myopia

Ophthalmic genetics

Multi-center clinical trials

Vision impairment in preschoolers

Strabismus

Amblyopia therapy

Electrophysiology

Retinopathy of prematurity

• 2003-2004 Fellow:

Stefanie Davidson, M.D.

• 2004-2005 Fellow:

Leila Khazaeni, M.D.

Fellows interact closely with clinical faculty, vision scientists, residents, and medical students.

RETINA

• Medical Retina -

1 year full-time,

2 years part-†time

• Medical Retina and†

Vitreoretinal Surgery -

2 years

• Preceptors:

Alexander J. Brucker, M.D.

Joshua L. Dunaief, M.D.

Stuart L. Fine, M.D.

Juan E. Grunwald, M.D.

Leonid E. Lerner, M.D., Ph.D.

Albert M. Maguire, M.D.

Robert A. Stoltz, M.D, Ph.D.

• Clinical Research

• Multi-center clinical trials in diabetic retinopathy and

AMD

• Pathogenesis of AMD

• 2003-2005

Medical Retina Fellow:

Carolyn Glazer-Hockstein, M.D.

• 2003-2005 Medical and

†Vitreoretinal Surgery Fellow:

George Mayo, M.D.

THE SCHEIE LOOKING GLASS • 13

P

OST

D

OC

& G

RADUATE

S

TUDENTS

SCHEIE’S RESEARCH LABORATORIES ARE HOTBEDS

OF LEARNING FOR SCIENTISTS AT EVERY LEVEL

Discovering and developing treatments and cures for devastating eye diseases requires years of painstaking research. Budding young scientists carry out much of this work while furthering their education. For the post doctoral, graduate and undergraduate students working with the Penn Ophthalmology vision scientists, learning is exciting and fun.

It’s not your typical day in the laboratory of Jean Bennett, M.D., Ph.D.

,

Professor of Ophthalmology and a Senior

Scientist in our department’s F.M. Kirby

Center for Molecular Ophthalmology .

Post doctoral fellow and now Research

Assistant Professor, Nadine Dejneka, Ph.D.

, called Bennett with an emergency. A mother mouse that had just given birth to a litter of lysosomal enzyme-deficient mice, died and the babies would not survive without her. But Bennett knew the trick – get another nursing mother mouse to urinate on the surviving litter, and she would accept them as her own.

In the highly complex world of vision research, sharing information at every level is the key to success. Dejneka joined the Bennett lab six years ago as a post doc and was appointed as Research

Assistant Professor in July 2004. Dejneka,

Enrico Surace, D.V.M.

and colleagues were the first to show that in utero gene therapy could be used therapeutically to treat an inherited retinal disorder in mice.

Dejneka designs her own experiments and has published numerous papers on gene therapy. Her work is focusing on using adeno-associated virus to permanently modify mutations in retinal genes. According to Dr. Bennett, “Nadine has superb technical and presentation skills and is an incredible teacher.”

Tonia Rex, Ph.D.

, came to the

F.M. Kirby Center three years ago as a post doc on an NIH training grant in gene therapy to work in the Bennett laboratory. A.k.a. “T. Rex,” Bennett describes her as a “dynamo” because she loves science and her enthusiasm is contagious. Her project, gene therapy for

Stargardt’s Disease, allows her to use her broad knowledge to quantify proteins in retinal cells, deliver corrective genes to mouse models, work with viral vectors, and test the efficacy of therapies. Her special talent is immunohistochemical techniques, particularly in dealing with problem tissue samples. Rex also has given seminars at the Penn and Jefferson campuses. She collaborates with Scheie scientists Edward Pugh, Ph.D. and

Samuel Jacobson, M.D., Ph.D.

Her goal is to combine teaching with research in an academic career. She devotes

Saturday mornings to teaching disadvantaged kids in North Philadelphia.

Jeannette Bennicelli, Ph.D.

, a molecular biologist working at Penn since

1978, is interested in defining the mechanisms underlying retinal degenerative diseases, in particular, focusing on the role of an EFEMP1 gene mutation in Malattia Levantinese and

Doyne Honeycomb Retinal Dystrophy.

Although these inherited diseases are rare, they have phenotypic features in common with Age-Related Macular

Degeneration (AMD), the leading cause of severe and irreversible vision loss in the

United States. Elucidation of the pathogenic mechanism involving mutated

EFEMP1 may give insight into the cause of

AMD. Bennicelli plans to apply for an NIH grant in February to continue her studies of EFEMP1.

After more than 20 years of cancer research, Bennicelli’s move to Bennett’s lab two years ago was a huge career change. “I enjoy applying my skill set to an entirely new set of questions and problems. The extensive resources available in the F.M.

Kirby Center have allowed me to apply the latest technologies to my research.

I also enjoy the opportunities afforded by the Center to interact with colleagues and to teach and mentor post

Continued on next page

14 • VOLUME 5, NUMBER 2 docs and students in the lab.”

When not in the lab, Bennicelli usually can be found riding or hanging out at

Chamounix Equestrian Center with her daughter Dana. She is a Board member at

Chamounix and a volunteer of the Work to Ride program that serves disadvantaged youth from Southwest

Philadelphia.

Nick Keiser, B.A.

, is a fourth-year graduate student and Ph.D. candidate, originally from upstate New York. He is working on the cellular and biochemical basis of inherited retinal disease and specifically on the cause of choroideremia.

His goal is to develop reagents to treat this disease and test them in an animal model. He plays the trombone in his spare time.

Daniel C. Chung, D.O.

, completed a pediatric ophthalmology fellowship in

2003 at the Cleveland Clinic and has been in the Bennett laboratory for 10 months.

He works on establishing non-viral methods of gene transfer into mouse retinal structures for future use in possible gene therapy studies, assists in maintaining the animal colonies, and performs subretinal injections on mice and other surgical techniques as needed by his colleagues in the lab. As a trained pediatric ophthalmologist with an interest in gene therapy, his ultimate goal is to become a clinician-scientist. He says, “I enjoy the concept of finding possible therapies for eye diseases that currently have no treatment, through gene manipulation techniques. Dr. Bennett promotes an atmosphere in which I am most productive.” Outside the lab, he spends most of his time with his three children, all under age 6. He loves, but rarely has time for, outdoor and wildlife photography.

Hal Schwartzstein , an undergraduate at Penn working at the F.M.

Kirby Center for the past year, assists the research scientists with their experiments.† This fall he will perform an experiment which consists of studying the progression of retinal degeneration in a new mouse model as part of an independent study class for his biology major.† He plans to attend medical

In the highly complex world of vision research, sharing information at every level is

school in 2006 with the ultimate goal of specializing

the key to success.

in ophthalmology. He says, “ The F.M.

Kirby Center allows me to apply my coursework to relevant experiments and to pursue my interest in ophthalmology.”

Outside of the lab, he participates in student government as the Senior Class

Vice President of Corporate Sponsorship, enjoys intramural sports and is an active member of the Phi Kappa Psi fraternity.

Vivian Simkins Lasko

Retinal Vascular Research Lab

Tatyana Metelitsina, M.D.

, completed her ophthalmology residency at The Filatov Research Eye Institute in

Odessa, Ukraine and came to the

U.S. in 2000 to pursue her interest in eye research. She is working as a post doctoral fellow under

Juan E. Grunwald, M.D.

, in the

Vivian Simkins Lasko Retinal

Vascular Research

Laboratory at Scheie.

Metelitsina and Grunwald have been working on a five-year project funded by the NIH to study choroidal blood flow in patients with AMD. The goal is to learn how choroidal blood flow in patients with AMD differs from blood flow in healthy eyes and how it changes with time and different interventions. Other studies in the pipeline are looking at ways to improve choroidal blood flow with pharmacological agents. Metelitsina

Tatyana Metelitsina and Juan Grunwald.

contemplated a career as a ballerina, but is happy she chose ophthalmology and would like to take care of patients someday.

THE SCHEIE LOOKING GLASS • 15

Pierce

Lab

Qin Liu, M.D., Ph.D.

, came to the U.S.

6 years ago from Beijing where she practiced ophthalmology and earned her

Ph.D. in molecular biology. She has been conducting research with Eric Pierce,

M.D., Ph.D.

, at the F.M. Kirby Center for Molecular Ophthalmology for

5 years. Her project is to identify functions of the RP1 protein and to understand how mutations in the RP1 protein cause vision loss. One way of identifying

“You find one thing and keep going and you open a new door

functions of the RP1 protein is to find candidate

to a new discovery.”

– Qin Liu, M.D., Ph.D.

proteins whose functions are already known and that interact with RP1 and then to deduce RP1’s function from them using a technique called co-immunoprecipitation.

Liu characterizes her job at the F.M.

Kirby Center as “fun,” and says, “You find one thing and keep going and you open a new door to a new discovery.”

Liu spends her spare time with her 13year old daughter. She was recently promoted to Research Associate and plans to continue in research, although sometimes when doing surgery on animals, she misses taking care of people.

Bertrand Deramaudt, Ph.D.

, hails from Strasbourg, France and has been at the F.M. Kirby Center since November

2001. Deramaudt’s research focuses on pre-RNA processing factor 8 protein

(PRPF8), which is expressed in every tissue in the body. A mutation in the gene makes the protein abnormal and can lead to a form of retinitis pigmentosa, but no harm elsewhere in the body. Deramaudt is designing several versions of a mouse model with the almost identical PRPF8 protein found in humans. In the “knockin” version, the gene mimics the disease in people; in the “knock-out” version, the gene is missing. The goal is to understand how the protein functions. Deramaudt spends his free time with his wife, who is expecting their second child, and his 5year old son.

Sara Achenbach, B.A.

, is a third year graduate student on the Pierce team. Her project, tied closely with that of Qin Liu, is to identify proteins that interact with RP1.

Achenbach uses a yeast-2 hybrid, has identified several candidate proteins and is confirming their identity in animal models. Achenbach loves teaching and wants, “to convey the excitement of biology to young people.” Outside the lab, she teaches aerobics and enjoys crocheting and swimming.

John Graziotto, B.S.

, is a fourth-year graduate student working on identifying the function and creating mouse models for the PRPF3 protein in similar fashion to

Bertrand Deramaudt’s work on PRPF8.

PRPF3’s normal function is required for

RNA splicing; Graziotto wants to know how the protein causes disease when mutated. He hopes to start a laboratory someday to conduct research on neurological diseases such as Alzheimer’s

“The most pleasurable and unique thing about working in a lab is having the chance to reason through problems with intelligent people.”

– Anna Bracewell and Parkinson’s. He works long hours, but when not working, enjoys playing the piano and going out with friends.

Anna Bracewell was graduated from

Penn with a B.A. in music theory and composition, but decided to change course and attend medical school. She takes science classes in the evenings and works the rest of the time on Eric Pierce’s projects as “Eric’s hands in the lab.” She values the collaboration at the

F.M. Kirby Center ; “The most pleasurable and unique thing about working in a lab is having the chance to reason through problems with intelligent people.” Not surprisingly, she spends her spare time as a musician: singing and playing the violin and piano.

Anna Bracewell, Eric Pierce, Sara Achenbach, John Graziotto,

Qin Liu and Bertrand Deramaudt

16 • VOLUME 5, NUMBER 2

New

NEI Award

Prepares

Clinician Scientists

to be

LEADERS

of the

FUTURE

In May 2004, the National Eye Institute awarded one of three prestigious K-12 Awards to support the Penn Vision Clinical Scientist Program.

Created in recognition of the fact that clinical and patient-oriented research should be conducted by a multidisciplinary research team, the NEI and

Penn Ophthalmology are committed to preparing young investigators to conduct research using this approach.

In May 2004, the National Eye Institute (NEI) awarded one of three prestigious K-12 Awards (technically called the

Institutional Mentored Clinical Scientist Development

Awards) to support the Penn Vision Clinical Scientist

Program (VCSP). Both the K-12 Award and the Penn VCSP were created in recognition of the fact that clinical and patient-oriented research have become increasingly more complex and often require a systems approach conducted by a multidisciplinary research team. The NEI and Penn

Ophthalmology are committed to preparing young investigators to conduct research using this approach.

The K-12 is different from other NEI training awards in that it grants Penn the freedom to choose individual recipients, subject to final NEI approval.

The Penn VCSP will be anchored in the Department of

Ophthalmology. Maureen G. Maguire, Ph.D.

, the

Carolyn Jones Professor of Ophthalmology and the

Director of the Center for Preventive Ophthalmology and

Biostatistics, is the principal investigator. Laura J. Balcer,

M.D., Jean Bennett, M.D., Ph.D., Stuart L. Fine, M.D.,

Graham E. Quinn, M.D., and Edward N. Pugh, Ph.D.

, serve on the Advisory Committee. These and other established investigators will serve as mentors to guide the choices that the VCSP physician-scientists make in their educational programs and research projects. Mentors also

Maureen G.

Maguire, Ph.D., the Carolyn Jones

Professor of

Ophthalmology and the Director of the Center for

Preventive

Ophthalmology and Biostatistics, is the principal investigator.

THE SCHEIE LOOKING GLASS • 17 advise mentees on activities necessary for professional development, collaboration among investigators, and development of long-term research programs. Lead mentors, either from the rich pool of talent within the department or from other Penn departments that have close ties to vision science, will be matched to each participant by area of interest. The Advisory

Committee will meet periodically with the VCSP participant and his/her mentor to discuss progress and to set goals and priorities.

The VCSP will take advantage of established educational programs within the university, the concentration of strong clinical and patient-oriented research programs currently ongoing within the Department of Ophthalmology, and the breadth of expertise available through Penn’s interdisciplinary institutes and centers. After completion of the VCSP, physician-scientists will be prepared to identify and prioritize important questions in their field, formulate a comprehensive approach to address the questions, and lead the efforts of a research team to provide answers.

Candidates selected for the

VCSP will have access to formal educational programs and applied research experience in a wide array of areas such as clinical epidemiology, singlecenter and multi-center clinical trials, health services research, bioethics, genetics, molecular biology, and neuroscience. Each year, one or two recently trained clinicians will be selected for participation in the VCSP.

Established investigators in clinical and patient-oriented research will serve as mentors to guide the choices made by VCSP participants in educational programs and research projects, as well as advise them on activities necessary for professional development, collaboration among investigators, and developing successful research programs.

All training programs incorporate the following common features:

• A didactic program of instruction

• Participation in journal clubs, lab meetings, and seminar series

• Development of a plan of research activities that provides a variety of experiences and an increasing amount of responsibility and independence

• Development of oral presentation and writing skills and other professional skills

• Regular review of the candidate’s plans and activities with evaluation and feedback provided to the participant

With our department’s commitment to recruit exceptionally well trained clinicians who are also prepared to conduct scientific research

(patient-oriented or laboratory),

Penn’s VCSP goes a long way towards maintaining our position as one of the outstanding eye institutes in the world. During each of the next

2 years, the department would like at least one of its K12 awardees to be focused on epidemiology or clinical research in the clinical disciplines of cornea, glaucoma, pediatric ophthalmology, or ocular oncology.

First

VCSP

Participant

The first VCSP participant is Andras

Komaromy, Dr.med.vet., Ph.D.

Although at first glance, the choice of a veterinarian may seem odd for a Clinician Scientist award, a quick look at Komaromy’s past training and research experience, as well as his research goals, shows that he is exactly the sort of person for whom the VCSP was designed. His strong interest in comparative ophthalmology and vision science began while a veterinary student in Switzerland. He completed a residency and Ph.D. program in comparative ophthalmology (pathogenesis of glaucoma in animal models) at the

University of Florida where he simultaneously developed a strong interest in retinal biology and electrodiagnostics that led him to a fellowship with Gus Aguirre, V.M.D.

, a veterinary ophthalmologist at the Penn School of Veterinary Medicine. Komaromy believes that animal models of inherited retinal diseases are an important link in understanding disease in man.

During the next 5 years, he will be refining his knowledge of retinal cell and molecular biology and of the fine points of electrophysiologic testing under the guidance of lead mentor

Aguirre and co-mentors Jean Bennett, M.D.,

Ph.D

and Samuel G. Jacobson, M.D., Ph.D.

18 • VOLUME 5, NUMBER 2

The

130th

Anniversary

MEETING

SCHEIE HONORS ALUMNI

AT 130TH ANNIVERSARY

MEETING

The annual alumni meeting was held in the Scheie Auditorium on May 21 and May 22. The featured guest speakers were Donald L. Budenz,

M.D., Associate Professor of

Ophthalmology at Bascom Palmer Eye

Institute and Daniel F. Martin, M.D.,

Professor of Ophthalmology at Emory

University. On Friday evening, May 21 a dinner dance was held at the Four

Seasons in honor of alumni from the classes of 1954, 1964, 1974, 1984 and

1994. Stuart L. Fine, M.D.

introduced and listed the many accomplishments of each honoree and presented them with a “Philadelphia,

Then and Now” book to commemorate the occasion. The faculty and staff were thrilled to meet many returning alumni and to hear directly what they have been doing since completing residency. We look forward to even greater alumni participation at the

2005 alumni meeting which will be held on May 20 and 21, 2005, with the evening event on May 20, 2005, again at the Four Seasons Philadelphia.

Harvey

Brown was instrumental in getting the class of 1974 to attend.

Lawrence Handler

Class of 1974 with their spouses are clockwise from front: Elliott and Jane Yolles, Harvey and Roanna Brown, Kay-Lee and Lai-Sung Eric Leung, Bonnie Kay, Carl Lindquist, Mike Kay and Julie Lindquist.

Thomas John

Douglas Young

THE SCHEIE LOOKING GLASS • 19

List of Alumni/ae Honorees

1954

Melvin G. Alper, M.D.

Anthony M. Spirito, M.D.

1964

Milton M. Connell, M.D.

Dugald H. Munro, M.D.

Herbert J. Nevyas, M.D.

Bernard Schneider, M.D.

1974

Harvey Allen Brown, M.D.

Smith F. Hogsett, M.D.

Michael L. Kay, M.D.

Lai-Sung Eric Leung, M.D.

Carl W. Lindquist, M.D.

Elliott A. Yolles, M.D.

1984

Kenneth V. Cahill, M.D., F.A.C.S.

Thomas John, M.D.

Randolph L. Johnston, M.D.

Jane G. Schweitzer, M.D.

Jerry C. Weinberg, M.D.

Allan E. Wulc, M.D., F.A.C.S.

1994

David W. Day, M.D.

Alyson L. Hall, M.D.

Lawrence F. Handler, M.D.

Neil S. Kalin, M.D.

Eileen R. Lilley, M.D.

Joseph D. Napolitano, M.D.

Dean P. Ouano, M.D.

Bruce Robert Saran, M.D.

Douglas A. Young, M.D.

The

130th

Anniversary

MEETING

Bruce Saran,

Eileen Lilley with husband

Robert Epstein, and Neil and

Joanie Kalin

20 • VOLUME 5, NUMBER 2

L

ECTURES

& S

EMINARS

CLASSES ARE ALWAYS IN SESSION AT SCHEIE

These educational forums provide an opportunity for the ophthalmologists intraining as well as the faculty to exchange ideas, share research findings and educate each other concerning state-of-the-art knowledge in vision research and clinical ophthalmology.

The Visiting

Professor Program

Visiting professor Susan B. Bressler, M.D. with

Robert Stoltz, M.D., Ph.D. and Carolyn Glazer-Hockstein, M.D.

A wealth of lectures, research seminars, conferences, visiting professorships and continuing medical educational (CME) courses remains an integral component of Scheie’s educational mission. These activities include: brings 10-15 distinguished clinicians and scientists for oneand-a-half days each year. The visit begins early Wednesday evening when the visiting professor is the guest of honor at a small dinner gathering attended by several faculty and house staff. On Thursday morning, the visiting professor participates in Ophthalmology

• A daily lecture and weekly conference series for residents and medical students (see calendar below)

• Weekly research meetings and journal clubs in each of the ophthalmic subspecialties

• A visiting professor series

• An ophthalmic heritage lecture series

Grand Rounds before delivering the first formal presentation. After the morning lecture, our guest visits with selected faculty and is escorted to a number of our special resource centers.

A noon seminar provides a relaxed forum for discussion between the visiting professor, clinical faculty, vision scientists

• Three commemorative lectures

• CME courses highlighted by our twoday annual alumni meeting in May.

and house staff. After lunch, the visiting professor may spend time with the

Department Chair and additional faculty.

Monday Tuesday Wednesday Thursday Friday

Clinical

Pathology

Conferences

As scheduled

Neuro-

Ophthalmology

7-8:00 (1st)

Basic Science

Lectures

7-10:00

Fluorescein

Angiography

Conference

7-8:00

Retina

Conference

7:30-8:30

(1st, 2nd and

5th)

Glaucoma

Conference

(3rd)

7-8:00

Retina

Journal Club

(4th)

7-8:00

Grand

Rounds

7-7:45

Visiting

Professor

Series

7:45-8:30

Cornea

Conference

7-8:00

(1st)

First-year students meet with Deputy

Rsidency twice per month

As Scheduled

The Visiting Professor Program has been successful, not only in bringing outstanding speakers to the department, but also in educating distinguished ophthalmologists and vision scientists about our department, residency, and research activities. Our expectation is for the visiting professor not only to leave a mark upon our Institution and staff but also to serve as an ambassador for our department wherever he or she may travel.

The Ophthalmic Heritage Lecture

Series focuses on how eye diseases and treatment have affected art, politics and society historically. The inauguration of this lecture series in 2003 acknowledges the Cogan Ophthalmic History Society, a national organization of some 50 ophthalmologists who meet annually to review our treasured ophthalmic history.

The series was inaugurated so that our house staff and faculty could better appreciate the major contributions made by giants in ophthalmology and vision science.

Commemorative lectureships honor faculty who have made outstanding contributions to Penn ophthalmology. The

Francis Heed Adler Lecture is named for the fourth department chair who served from 1935-1960. Dr. Adler was a secretary of the American Board of Ophthalmology, a noted physiologist and author, and a recognized national leader in organized ophthalmology. The Jeffrey Berger

Memorial Lecture was named for an exceptionally talented young physicianscientist whose untimely passing in 2001 left an enormous void in the department.

Dr. Berger was a member of the Retina

Service and the Director of the Computer

Vision Laboratory. The Louis Karp

Memorial Lecture acknowledges contributions made by a busy clinical practitioner who (despite his role as Chief of Ophthalmology at the Pennsylvania

Hospital), came weekly to Scheie to deliver a one-hour lecture to the residents on the ophthalmic pathology service. Each year a recognized expert in ophthalmic pathology is invited to deliver this lecture.

Three or four times a year, the department sponsors a weekend

THE SCHEIE LOOKING GLASS • 21 continuing medical education course in a particular subspecialty. The course is taught by invited guest speakers and by Scheie faculty and staff.

Traditionally the weekend begins on Friday afternoon, when the visiting professor presents interesting cases to the residents. On Friday evening, there is typically a social function. Saturday morning features a clinically oriented conference followed by a discussion of interesting cases. These CME courses provide an opportunity for members of the department and the surrounding ophthalmic community to discuss current information about patient care and relevant clinical research.

The highlight of the academic year is the Annual Meeting in May that includes a two-day continuing medical education course. Invited guest speakers as well as medical students, residents, faculty and alumni present topics on their current clinical and research interests.

During the two-day course, one evening is devoted to a social function (typically with dinner and dancing) at one of the premier Philadelphia hotels during which time alumni returning for a special anniversary are honored. Friends of the

Scheie Eye Institute, donors to the department’s programs, the University of

Pennsylvania Health System leaders, and

Chairs from other Penn Med departments are invited to attend this celebratory event.

This year in March of 2005 the department will inaugurate the Penn

Ophthalmology Review Course, a comprehensive review of ophthalmology for residents and for ophthalmologists around the country who may be preparing to take the American Board of

Ophthalmology written qualifying examination. The course will be taught in part by Penn Ophthalmology faculty and in part by five distinguished professors from outstanding programs across the country. Nicholas J. Volpe is the course director. For further information, contact Jenny Bartelle at 215-662-8069 or jenny.bartelle@uphs.upenn.edu.

VISITING

PROFESSORS

Sander

Dubovy,

M.D.

, gave the 2004

Louis Karp

Lecture.

Visiting professor

Elias I.

Traboulsi, M.D.

Thomas A.

Weingeist,

Ph.D., M.D., gave the 2004

Francis Heed

Adler Lecture.

Joel S. Schuman, M.D.

, the featured speaker at the Glaucoma CME in

February 2004, is shown with

Prithvi Sankar, M.D. and

Jody Piltz-Seymour, M.D.

William S. Tasman, M.D.

,

(pictured in photo above to the left) presented an

Ophthalmic Heritage lecture titled Eye

Disorders and How

They Affect History and the Arts and showed a painting, “A Self

Portrait,” by Edvard

Munch as seen through the eyes of the artist who suffered from macular degeneration.

22 • VOLUME 5, NUMBER 2

Penn Ophthalmology

Review Course

March 8-12, 2005

Hyatt Regency Philadelphia at Penn’s Landing

Course Director:

NICHOLAS J. VOLPE, M.D.

ONCOLOGY

David H. Abramson, M.D., FACS

Memorial Sloan-Kettering

Cancer Center

Cornell/Weill Medical College

OCULOPLASTICS/ORBIT

Roberta E. Gausas, M.D.

Scheie Eye Institute at Penn

OPTICS/REFRACTION

David G. Hunter, M.D., Ph.D.

Harvard/Children’s Hospital

Boston

RETINA

Alexander J. Brucker, M.D.

Joshua L. Dunaief, M.D., Ph.D.

Stuart L. Fine, M.D.

Leonid E. Lerner, M.D., Ph.D.

Albert M. Maguire, M.D.

Robert A. Stoltz, M.D., Ph.D.

Scheie Eye Institute at Penn

RETINAL DEGENERATION

Samuel G. Jacobson, M.D., Ph.D.

Scheie Eye Institute at Penn

For further information, or to request a brochure, contact Jenny Bartelle

215-662-8069 or

COMPREHENSIVE

OPHTHALMOLOGY

Mina Massaro-Giordano, M.D.

Scheie Eye Institute at Penn jenny.bartelle@uphs.upenn.edu

GLAUCOMA

Eydie G. Miller-Ellis, M.D.

Prithvi S. Sankar, M.D.

Scheie Eye Institute at Penn Check our Website www.penneye.com

Click on “Education” then “CME Courses”

CATARACT/CORNEA

Stephen E. Orlin, M.D.

Scheie Eye Institute at Penn

N

N

E

P

O

PH

THALMO

Retina

Oconology

LO

Glaucoma

Catarct/Cornea

Oculoplastics/Orbit

IE

V

Y

G

R

E

SE

Optics/Refraction

Retinal Degeneration

Comprehensive Ophthalmology

Pediatrics/Strabismus

Refractive Surgery

Neuro-Ophthalmology

UR

Pathology

Uveitis

CO

W

PEDIATRIC

OPHTHALMOLOGY/

STRABISMUS

Michael X. Repka, M.D.

Wilmer Institute at Johns

Hopkins

REFRACTIVE SURGERY

Michael E. Sulewski, M.D.

Scheie Eye Institute at Penn

UVEITIS

Russell N. Van Gelder, M.D., Ph.D.

Washington University School of

Medicine

NEURO-OPHTHALMOLOGY

Nicholas J. Volpe, M.D.

Scheie Eye Institute at Penn

PATHOLOGY

Myron Yanoff, M.D.

Drexel University

University of Pennsylvania Health System

THE SCHEIE LOOKING GLASS • 23

U

NIVERSITY OF

P

ENNSYLVANIA

D

EPARTMENT OF

O

PHTHALMOLOGY

www.penneye.com

PUBLICATIONS

COMMITTEE

STUART L. FINE, M.D.

Chairman, Director and Editor

NICHOLAS J. VOLPE, M.D.

Vice Chair Clinical Practice

Residency Program Director

CHERYL ATKINS-LUBINSKI

Vice Chair and

Chief Operating Officer

JENNY BARTELLE

Coordinator, Educational Activities

MEG MACFARLANE

Manager, Administrative Services

MAUREEN G. MAGUIRE, Ph.D.

Professor of Ophthalmology

FRANCIS J. MANNING, M.D.

President of the Alumni

Association

ANN SACKS

Director of Development and

Alumni Relations

Photography by

Bill Nyberg and Jim Berger

L

ECTURES AND

S

EMINARS

O

CTOBER

2004

TO

J

UNE

2005

Visiting Professor Lectures are on Thursdays:

7:45-8:30 AM • Scheie Eye Institute Auditorium-Lower Level

Noon-1:00 PM • Thayer Conference Room, SEI 5th Floor

OCTOBER 7, 2004

C. P. Wilkinson, M.D.

Greater Baltimore Medical Center

JANUARY 6, 2005

Samuel G. Jacobson, M.D., Ph.D.

Scheie Eye Institute/

University of Pennsylvania

MARCH 8-12, 2005

Penn Ophthalmology

Review Course

Hyatt Regency Philadelphia at

Penn’s Landing OCTOBER 14, 2004

Jeffrey Berger

Memorial Lecture

Donald Zack, M.D., Ph.D.

Johns Hopkins University

JANUARY 13, 2005

Tomas S. Aleman, M.D.

Scheie Eye Institute/

University of Pennsylvania

MARCH 31, 2005

Stuart Seiff, M.D.

University of California, San Francisco

NOVEMBER 11, 2004

Juan E. Grunwald, M.D.

Scheie Eye Institute/

University of Pennsylvania

JANUARY 20, 2005

Stuart J. McKinnon, M.D., Ph.D.

University of Texas

APRIL 14, 2005

Joshua L. Dunaief, M.D., Ph.D.

Scheie Eye Institute/

University of Pennsylvania

NOVEMBER 18, 2004

Louis Karp Memorial Lecture

W. Richard Green, M.D.

Johns Hopkins University

NOVEMBER 20, 2004

Neuro-ophthalmology of

Optic Neuritis & Multiple

Sclerosis

8:00 am - 12:00 noon

JANUARY 22, 2005

Jamie Brandt, M.D.

University of California, Davis

FEBRUARY 3, 2005

Barrett Haik, M.D.

University of Tennessee, Memphis

FEBRUARY 10, 2005

Eydie Miller-Ellis, M.D.

Scheie Eye Institute/

University of Pennsylvania

FEBRUARY 12, 2005

Francis Heed Adler Lecture

Dan B. Jones, M.D.

Cullen Eye Institute/

Baylor College of Medicine

8:00 am - 12:00 noon

APRIL 21, 2005

Creig S. Hoyt, M.D.

University of California, San Francisco

MAY 12, 2005

Albert S. Jun, M.D., Ph.D.

Johns Hopkins University

MAY 20-21, 2005

131st Anniversary Meeting

Honoring Alumni from 1955, 1965,

1975, 1985, 1995 DECEMBER 2, 2004

Jonathan C. Horton, M.D., Ph.D.

University of California,

San Francisco

DECEMBER 9, 2004

Artur V. Cideciyan, Ph.D.

Scheie Eye Institute/

University of Pennsylvania

JUNE 2, 2005

Brian J. Forbes, M.D., Ph.D.

Scheie Eye Institute/

University of Pennsylvania

Children’s Hospital of Philadelphia

FEBRUARY 17, 2005

Terri Young, M.D.

Scheie Eye Institute/

University of Pennsylvania

Children’s Hospital of Philadelphia

JUNE 9, 2005

R. Doyle Stulting, M.D., Ph.D.

Emory University DECEMBER 16, 2004

David W. Parke, II, M.D.

Dean McGee Eye Institute/

University of Oklahoma

For more information, please contact

Marilyn Katz at 215-662-8657 or email katzm@uphs.upenn.edu

NON PROFIT

ORGANIZATION

U.S. POSTAGE

P A I D

PERMIT NO. 2563

PHILA. PA 19104 Department of Ophthalmology

Scheie Eye Institute

Comments, suggestions?

Please write, fax or e-mail to:

Ann Sacks

Scheie Eye Institute

51 North 39th Street

Philadelphia, PA 19104

Phone: 215-662-8774

Fax: 215-662-1721

Email: ann.sacks@uphs.upenn.edu

To remove name from mailing list, call above number.

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