The Journal of Arthroplasty Vol. 14 No. 3 1999 In Vivo D e t e r m i n a t i o n of Condylar Lift-off a n d S c r e w - H o m e in a M o b i l e - B e a r i n g Total K n e e A r t h r o p l a s t y James B. S t i e h l , M D , * D o u g l a s A. D e n n i s , MD, t Richard a n d H a l S. C r a n e , D. K o m i s t e k , PhD,-~ MDt Abstract: Twenty subjects implanted with the low-contact stress (LCS) cruciatesacrificing, mobile-bearing total knee arthroplasty underwent dynamic videofluoroscopy during in vivo weight-bearing conditions using a 3-dimensional computer-aided design (CAD) interactive modeling method. Ninety percent of the subjects demonstrated significant lift-off during stance phase of gait. Condylar lift-off was present at both the medial and the lateral condyles. The maximal medial lift-off was 2.12 mm, whereas the greatest lateral lift-off was 3.53 ram. The maximal positive screw-home was 9.6 °, whereas the maximal negative or reverse screw-home was 6.2 ° . The average screw-home rotation was positive 0.5 ° . In 50% of patients, medial condylar translation was unexpectedly greater than lateral condylar motion. Condylar lift-off and screw-home motion are significant kinematic functions in this rotationally unconstrained total condylar knee arthroplasty. Key words: total knee arthroplasty, kinematics, condylar lift-off, screw-home rotation. In total k n e e arthroplasty (TKA), k n o w l e d g e of k i n e m a t i c function is necessary if the in vivo weightbearing forces a n d shear stresses applied to the bearing surfaces are to be determined. Posterior cruciate-retaining designs t e n d to h a v e lower conformity to allow greater rotational freedom, believed to be necessary for n o r m a l function a n d to lower stresses at the i m p l a n t - b o n e interface. Posterior cruciate-sacrificing implants h a v e higher conformity, w h i c h increases i m p l a n t stability a n d i m p r o v e s w e a r characteristics. F r o m a r e v i e w of the literature, w e could find no clear a d v a n t a g e of one t e c h n i q u e or implant, a l t h o u g h certain posterior cruciate-retaining designs h a v e s h o w n a dis- turbing incidence of osteolysis not recognized with older posterior cruciate-sacrificing total condylar designs [1-5]. Blunn et al. [6] d e m o n s t r a t e d p a t t e r n w e a r a n d peripheral w e a r in designs with polyethylene delamination, k n o w n to result f r o m the m o s t severe wear. The potential for femoral-tibial separation or condylar lift-off during weight-bearing has b e e n postulated by several authors. Dennis eta]. [7] w e r e able to d e m o n s t r a t e condylar lift-off in b o t h posterior c r u c i a t e - r e t a i n i n g a n d p o s t e r i o r c r u c i a t e sacrificing designs using in vivo d y n a m i c videofluoroscopy. Nilsson et al. [8] h a v e also s h o w n this p h e n o m e n o n using stereoradiography. The clinical implication of this finding is that edge loading at the peripheral surface of the tibia] plateau m a y be deleterious, particularly if a Jlat-on-flat condylar design is used [9,10]. In vivo rotational m o v e m e n t in TKA has b e e n investigated using several methods, including roentgen s t e r e o p h o t o g r a m m e t r y , videofluoroscopy, a n d electromagnetic orthotic fixtures [8,11,I2]. These From the *Midwest Orthopaedic Biomechanical Laboratory, St. Luke's Hospital, Milwaukee, Wisconsin; and ~-Rose Musculoskeletal Research Laboratory, Rose Medical Center, Denver, Colorado. Submitted March 15, 1998; accepted September 1 l, 1998. Reprint requests: James B. StiehI, MD, 2015 E. Newport, #703, Milwaukee, WI 53211. Copyright © 1999 by Churchill Livingstone® 0883-5403/99/1403-0006510.00/0 293 294 The Journal of Arthroplasty Vol, 14 No. 3 April 1999 studies have typically s h o w n screw-home or external rotation of the tibia in extension with internal rotation as the angle of flexion increases. Alterations from the rotation of the n o r m a l knee m a y be related to anterior cruciate deficiency, prosthetic geometry, and differences in surgical technique in individual patients. Knowledge of rotational m o v e m e n t is an important consideration for understanding polyethylene wear patterns, in which exaggerated sliding motion m a y produce detrimental delamination wear. Dynamic videofluoroscopy has emerged as a valuable scientific tool for investigating in vivo kinematic performance of TKA. Our initial experience with the technique allowed the determination of 1-point contact in the sagittal plane, such as the lateral femoral condyle with the tibial plateau {13]. More recently, we have used 3-dimensional model fitting to determine kinematic relationships accurately. With this method, determination of both medial and lateral condylar position as well as condylar lift-off and s c r e w - h o m e rotation can be m e a s u r e d in gait [ 14]. The purpose of this paper is to use in vivo fluoroscopy with an interactive model-fitting technique to examine coronal and transverse plane m o t i o n in a mobile-bearing TKA during gait. The results are compared with our prior experience with fixed bearing designs and with information on n o r m a l knees from literature review. The low-contact stress (LCS) rotating platform prosthesis (Depuy, Inc, Warsaw, IN) is a posterior cruciate-sacrificing implant that was designed to have u n c o n s t r a i n e d rotational f r e e d o m and conforming coronal plane articulation that allowed condylar lift-off. Materials and Methods Before inclusion in this study, each patient reviewed and signed an investigation review b o a r d approved consent form. We p e r f o r m e d dynamic fluoroscopy u n d e r weight-bearing conditions in 20 patients with a c e m e n t e d posterior cruciate-sacrificing LCS mobile-bearing (rotating platform) TKA (Deputy, Warsaw, IN). The patients were chosen on the basis of an excellent clinical result (>90/90) using the Knee Society scoring system. The time from surgery to analysis was a m i n i m u m of 12 m o n t h s in all cases. The resultant femoral-tibial alignment was n o r m a l in all (range, 5o-7 °) with excellent stability in extension. Each patient u n d e r w e n t 2-dimensional videofluoroscopy using a VJ Works fluoroscopy unit (VF Works, Palm Harbor, FL), which produces images at a rate of 30 Hz. The technique required the patient to take 1 step while walking on an elevated platform. The radiology technician t h e n followed the knee joint by attempting to keep the lateral side of the knee centered on the x-ray machine's fluoroscopic image at all times. This was done to simulate the walking gait cycle from heel-strike to toe-off. Video Analysis We have evolved our video analysis to an interactive model-fitting technique. This m e t h o d fits 3-dimensional computer-aided design (CAD) solid models of the femoral and tibial implants onto the 2-dimensional fluoroscopic silhouette images. The fluoroscopic images had b e e n stored on videotapes for subsequent redigitization using a frame grabber. The videos were t h e n analyzed on a c o m p u t e r workstation using the interactive c o m p u t e r algorithm (Fig. 1). The femoral and tibial c o m p o n e n t s of the best-fit overlay were rotated into the precise sagittal plane to measure anteroposterior contact of the medial and lateral condyles and screw-home rotation, which is a function of these points. Four distinct positions of the sagittal plane fluoroscopy images were analyzed during the n o r m a l gait cycle including i) at heel-strike, ii) at 33% of stance phase, iii) at 66% of stance phase, and 4) at toe-off. These positions were confirmed using a second video camera to determine the exact frame of heel-strike and toe-off and calculating 33 % and 66 % of the weight-bearing gait cycle. The overlay model was t h e n rotated into the frontal plane to measure the distance from the femoral condyle to the tibial plateau to determine femoral-tibial lift-off. M e a s u r e m e n t of condylar liftoff is done by comparing the difference of the medial and lateral condylar distances to the tibial baseplate. It is assumed that the condyles are in a similar plane of tibial contact, and there should be little difference in plastic thickness. Rotation was d e t e r m i n e d from an arbitrary reference line that was perpendicular to the sagittaltibial plane. Medial and lateral condylar translation at each point in the gait cycle were used to calculate rotation. Determination of the specific medial and lateral condyle has b e e n easy for several reasons. First, the leg involved is k n o w n , and therefore medial and lateral overlay prosthetic condyles are k n o w n . Second, most implants are asymmetric, and condylar shapes become obvious. Third, for symmetric implants, the lateral condyle is always closer to the x-ray tube and is larger. For the anteroposterior reference, a positive reference is d e n o t e d as anterior and a negative posterior to the sagittal plane midline of the tibial prosthesis. Normal or positive s c r e w - h o m e m o t i o n was defined as tibial internal rotation in relation to the distal f e m u r with increasing flexion [15]. Femoral-tibial Condylar Liftoff and Screw Home in Mobile-Bearing TKA Fig. 1. Interactive 3-dimensional CAD modeling showing (A) CAD model overlay superimposed on 2-dimensional videofluoroscopy frame. (B) Example of sagittal view of solid model. (C) Example of coronal view of solid model. (D) Coronal view demonstrating condylar lift-off. A • Stiehl et al. 295 B C contact of the medial a n d lateral condyles could h a v e 3 patterns of translation to cause this motion: i) Lateral condyle m o v e s m o r e posterior t h a n the medial; ii) lateral condyle m o v e s posterior, w h e r e a s the medial condyle m o v e s anterior; a n d iii) lateral condyle m o v e s less anterior t h a n the medial condyle. Reverse or negative s c r e w - h o m e was defined as tibial external rotation in relation to the f e m u r w i t h increasing flexion. Femoral-tibial contact of the medial a n d lateral condyles could h a v e 3 patterns of translation to cause the motion: i) medial condyle m o v e s m o r e posterior t h a n the lateral; ii) medial condyle m o v e s posterior, w h e r e a s the lateral m o v e s anterior; a n d iii) medial condyle m o v e s less anterior t h a n the lateral condyle. Error Analysis An error analysis was p e r f o r m e d to d e t e r m i n e the reproducibility a n d accuracy of m e a s u r e m e n t of o u r technique. This analysis was done b y fluoroscoping i m p l a n t c o m p o n e n t s m o u n t e d on a 6 ° of f r e e d o m apparatus. Accurate positioning of the c o m p o n e n t s was achieved using rotational a n d translational stages w i t h a n accuracy of 15 arc seconds a n d 0.01 m m . The c o m p o n e n t s w e r e set in an initial position, t h e n rotated and translated to k n o w n values. Fluoroscopic images of the c o m p o n e n t s w e r e created at each setting. The 3-dimensional model-fitting process was p e r f o r m e d for each setting of the rotational D a n d translational stages to d e t e r m i n e the relative pose of the c o m p o n e n t s . A second d y n a m i c test was p e r f o r m e d to d e t e r m i n e the effect of motion. The c o m p o n e n t s w e r e pulled t h r o u g h the fluoroscopic scene at a variable speed b e t w e e n 0.5 a n d 1.0 feet per second. The translational and rotational 3-dim e n s i o n a l model-fitting technique was accurate to 0.5 m m and 0.5 ° [14]. A threshold of 0.75 m m and 0.75 ° (50% safety factor) was used to account for u n k n o w n variables. Results Condylar Lift-off Significant condylar lift-off was seen in 90% of subjects at heel-strike a n d 66% of subjects at stance phase a n d toe-off. In 50% of TKAs, we f o u n d b o t h medial and lateral lift-off, w h e r e a s only 15% s h o w e d nonsignificant lift-off (<0.75 m m ) . The greatest medial lift-off was 2.12 m m , w h e r e a s the greatest lateral was 3.53 m m (Table 1). Screw-Home Rotation Seven of 20 patients d e m o n s t r a t e d positive screwh o m e rotation w i t h tibial internal rotation o n flexion. In 5 subjects, the overall rotation was m i n i m a l or insignificant ( < 0.75). Eight patients s h o w e d negative s c r e w - h o m e w i t h tibial external rotation on 296 The Journal of ArthroplastyVol. 14 No. 3April 1999 flexion. Six patients demonstrated greater t h a n 5 ° rotation with the maximal positive s c r e w - h o m e of 9.6 °, whereas the maximal negative s c r e w - h o m e was negative 6.2 ° . The average s c r e w - h o m e for the group was a positive 0.5 °. We could not find a relationship b e t w e e n condylar lift-off and a specific pattern of s c r e w - h o m e because condylar lik-off was seen with all screw-home possibilities (Table 2; Fig. 2). Normal s c r e w - h o m e with medial condylar pivot and the medial condyle moving less posterior t h a n the lateral condyle with gait was seen in only 2 patients. Five patients demonstrated abnormal positive screw-home, with the medial condyle m o v i n g more anterior t h a n the lateral in 4 and the medial condyle m o v i n g anterior, whereas the lateral condyle m o v e d posterior in 1 (Table 3). Reverse s c r e w - h o m e was seen in 13 patients. In 5 subjects, the medial condyle translated m o r e posterior t h a n the lateral. For 3 knees, the medial condyle translated posterior, whereas the lateral m o v e d anterior. In 5 cases, the medial condyle translated less anterior t h a n the lateral. Table 2. Screw-Home Results During 0%, 33%, 66%, and 100% Stance Phase of Gait Cycle* Subject 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Average 0%-33% 33%-66% 66%-100% 0%-100% 2.46 -4.59 -2.92 9.37 4.04 1.04 -1.42 - 1.69 -1.01 0.57 -0.12 -2.72 0.10 0.27 7.22 4.75 -1.60 0.19 --0.96 --0.93 0.29 -2.22 -9.I4 -1.48 1.04 - 1.11 -0.26 1.73 0.21 -2.29 0.14 --2.03 2.33 -2.13 --2.48 3.14 0.91 --1.47 5.45 0.62 - 5.78 1.19 5.90 1.57 0.00 1.78 -0.94 -4.83 0.22 1.60 -0.78 4.39 3.90 4.93 -1.56 1.66 0.14 -0.04 -5.70 0.49 - 3.03 -5.62 -6.16 9.45 5.08 1.72 -2.62 -4.79 -1.03 -0.12 -0.76 -0.35 6.33 3.07 3.18 9.55 -0.55 -1.32 - 1.21 -0.81 0.60 - 0.44 0.34 0.50 *Positive = tibia i n t e r n a l r o t a t i o n ; n e g a t i v e = tibia e x t e r n a l rotation. Discussion Dynamic fluoroscopy has p r o v e d to be invaluable for investigating kinematic performance of TKA. Using c o m p u t e r vector analysis, we have previously identified abnormal anteroposterior translation, loss Table 1. Lift-Off Results* % of Gait Subject 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Average 0% 33 % 66% 100% 0.81 0.53 0.48 0.81 0.21 -1.41 1.60 -1.31 0.00 0.00 0.91 --0.47 1.01 0.42 1.78 0.66 0.00 1.56 0.40 -I.15 -1.93 0.54 -0.25 0.00 -1.50 2.29 -1.34 0.44 -0.42 -0.13 1.70 - 1.89 --0.22 0.02 -2.05 -0.06 1.19 -0.55 1.59 1.87 1.60 -1.35 -0.09 0.80 -0.55 -1.07 1.08 0.52 1.39 0.09 0.00 0.47 1.19 1.19 -0.43 0.47 -0.46 0.00 0.45 0.00 1.42 -0.16 0.65 2.06 0.19 1.60 1.15 -0.09 1.10 0.85 -0.27 2.12 -1.87 -1.87 -0.54 -0.25 -0.04 -1.70 -3.53 0.89 0.78 1.00 0.63 1.05 *Negative = medial condyle; positive = lateral condyle. of posterior femoral rollback, and lateral condylar lift-off in posterior cruciate-retaining TKAs [13]. Evolution of our technique led to an inverse perspective m e t h o d that required developing a library of CAD implant models that could be m a t c h e d to each isolated femoral and tibial implant on the video frame [14]. More recently, we have used an interactive modeling system that allows us to manipulate the 3-dimensional CAD model implant precisely onto the video 2-dimensional image. This m e t h o d does not require precise sagittal plane positioning of the patient's knee because the video image can accurately be superimposed e v e n with some degree of malrotation. The reason for this is that the complex g e o m e t r y of the implant image allows for only 1 finite position of the CAD model in space. The fluoroscopic image can t h e n be extracted leaving the CAD image from which kinematic calculations are possible. We have b e e n able to demonstrate that condylar lift-off occurs in all TKAs that we evaluated regardless of surgical technique, including posterior cruciate retention, sacrifice, or substitution. Most of the mobile-bearing TKAs of this study showed both medial and lateral condylar lilt-off using a posterior cruciate-sacrificing technique. The largest a m o u n t of lift-off was identified in the lateral compartment. Dennis et al. [7] evaluated posterior cruciatesubstituting TKAs, finding that medial condylar lift-off occurred about equal to lateral lift-off. In Condylar Liftoff and Screw Home in Mobile-Bearing TKA • Stiehl et al. 297 14 Subject 1 12 ¢ Subject 2 10 Subject 3 8 Subject 4 Subject 5 F i g . 2. Five r a n d o m l y s e l e c t e d patients demonstrating diverse 4 2 d i s t r i b u t i o n of r o t a t i o n . 0 -2 / -4 / -6 Heel-strike 33%Stance 66%Stance Toe-off % of Stance Phase posterior cruciate-retaining TKAs, condylar lift-off was predominantly lateral. Using a different method, roentgenographic stereophotogrammetry, Nilsson et al. [8] were also able to demonstrate this p h e n o m enon, w h i c h they defined as tibial rotation (abduction/adduction) about the sagittal axis. In their study, the LCS mensical-bearing implant revealed a m e a n of 3 ° adduction at 50 ° flexion, similar to normal knees. The fact that condylar lift-off occurs is not surprising considering the adduction and abduction m o m e n t s that have b e e n hypothesized with gait {16]. Condylar lift-off becomes a significant issue for TKA design w h e n one considers peripheral edge loading that is likely with fiat-on-fiat total condylar designs [9,10]. Wasielewski et al. [17] and Blunn et al. [6] f o u n d peripheral wear and pattern wear with severe polyethylene delamination in these designs. Because abnormal medial c o m p a r t m e n t anteroposterior translation is c o m p o u n d e d with lateral condylar lift-off, the posterior medial wear patterns identi- Table 3. Screw-Home Mechanism Internal Tibial Rotation + + + Type Normal Reverse Reverse Normal Normal Reverse Condylar M o t i o n Med Med Med Med Med Med Post < Lat Post Post > Lat Post Post:Lat Ant Ant:Lat Post Ant:Lat Ant Ant < Lat Ant Med, medial; Post, posterior; Lat, lateral; Ant, anterior. No. Patients 2 5 3 1 4 5 fled in those studies are expected. The coronal geometry of the LCS rotating platform implant used in this study is Conforming in the coronal plane to allow for congruity with lift-off. Retrievals of this implant have revealed minimal wear of the polyethylene surface after e x t e n d e d clinical use [ 18]. High rotational constraint in TKA has been recognized as a p r e d o m i n a n t cause of failure in early hinge designs. Rotational m o v e m e n t of the normal knee was studied by LaFortune et al. [19] using high-speed p h o t o g r a p h y and implanted Steinman pins as skeletal markers in n o r m a l walking volunteers. Internal rotation at heel-strike and toe-off m e a s u r e d slightly less than 5 °, whereas external rotation increased to 9 ° during swing phase. Screwhome m o v e m e n t has been described as relative external rotation of the tibia in relation to the f e m u r near full extension [20]. Early investigators postulated that abnormalities of knee function are related to disturbance of this mechanism. K a r r h o l m et al. [21] demonstrated significant alterations in rota~ tion with anterior cruciate-deficient knees finding a m o r e externally rotated tibia in extension followed by decreased internal rotation in flexion. Nilsson et al. [8] reported similar findings with several different posterior cruciate-retaining TKAs, noting less terminal screw-home or terminal external tibial rotation, again relating to the m o r e externally rotated tibia in extension and decreased internal rotation in flexion. Nilsson et al. [9] investigated the LCS meniscalbearing total knee implant, finding that initial extension started with a more externally rotated tibia t h a n n o r m a l and had minimal internal rotation 298 The Journal ofArthroplasty Vol. 14 No. 3April 1999 (mean, 0.5 °) during flexion. Using the LCS rotating platform implant, w h i c h sacrifices the posterior cruciate ligament, our study f o u n d similar overall internal rotation (mean, 0.5 ° ) during flexion, but our patients d e m o n s t r a t e d m u c h greater variability with rotation. For example, only 7 of our patients d e m o n s t r a t e d internal tibial rotation with flexion. Of that group, only 2 patients had n o r m a l screwh o m e with lateral femoral tibial contact m o v i n g m o r e posterior t h a n medial contact on flexion. The other 5 had significant anterior sliding of the medial condyle to cause internal rotation. Reverse screwh o m e was seen in 13 of our patients, in w h o m there was actually tibial external rotation in flexion. This reverse s c r e w - h o m e resulted from exaggerated lateral condylar anterior translation in flexion or medial condylar posterior translation that exceeded lateral translation. Two patients in our study d e m o n strated greater t h a n 9 ° of tibial internal rotation with gait. Other authors have been able to demonstrate significant tibial rotation of u n c o n s t r a i n e d TKAs. E1 Nahass et al. [11] evaluated the kinematic condylar posterior cruciate-retaining TKA using electrogoniometers, finding that tibial external rotation on extension varied from 4.4 ° to 11.3% Markovich et al. [121 used in vivo videofluoroscopy to evaluate weight-bearing step-up activity finding 8 ° of tibial external rotation from flexion to extension. This rotation occurred from posterior translation of the medial femoral condyle in extension (average, 6.3 mm), whereas lateral condylar translation was limited. We have s h o w n that significant rotation and condylar lift-off were present in a cohort of successfully performed TKAs. The results of our study suggest that a complex rotational m o t i o n m a y exist in m a n y with regard to femoral-tibial contact of the condyles in TKA. Transverse plane rotations and lift-off for each individual patient were highly variable, reflecting the inability to restore perfectly the n o r m a l kinematics of the joint. We believe that these kinematic abnormalities, w h e n exaggerated, can be related to some of the current problems of TKA, such as peripheral pattern and posterior medial condylar wear. Further studies are necessary to investigate the complex relationship of biomechanical and biomaterial p e r f o r m a n c e in TKA. These data suggest that designs such as the LCS mobilebearing platform, w h i c h a c c o m m o d a t e significant rotation and lift-off while maintaining high articular surface congruity, m a y importantly diminish contract surface stresses. This m a y represent an optimal solution to these unresolved kinematic derangements. References 1. 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LaFortune MA, Cavanagh PR, Sommer HJ, Kalenak • Stiehl et al. 299 A: Three-dimensional kinematics of the h u m a n knee during walking. J Biomech 25:347, 1992 20. Hallen LG, Kindahl O: The "screw-home" m o v e m e n t in the knee joint. Acta Orthop Scand 37:97, 1966 21. Karrholm J, Selvik G, Elmlqvist LG, Hansson LI: Active knee motion after cruciate ligament rupture: stereoradiography. Acta Orthop Scand 59:158, 1988